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PDB: 3278 件

4DYM
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Crystal structure of the ACVR1 kinase domain in complex with the imidazo[1,2-b]pyridazine inhibitor K00135
分子名称: 1-(3-{6-[(CYCLOPROPYLMETHYL)AMINO]IMIDAZO[1,2-B]PYRIDAZIN-3-YL}PHENYL)ETHANONE, Activin receptor type-1, GLYCEROL, ...
著者Chaikuad, A, Sanvitale, C, Cooper, C, Canning, P, Mahajan, P, Daga, N, Petrie, K, Alfano, I, Gileadi, O, Fedorov, O, Krojer, T, Filippakopoulos, P, Muniz, J.R.C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC)
登録日2012-02-29
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Crystal structure of the ACVR1 kinase domain in complex with the imidazo[1,2-b]pyridazine inhibitor K00135
To be Published
3TJ1
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Crystal Structure of RNA Polymerase I Transcription Initiation Factor Rrn3
分子名称: RNA polymerase I-specific transcription initiation factor RRN3
著者Blattner, C, Jennebach, S, Herzog, F, Mayer, A, Cheung, A.C.M, Witte, G, Lorenzen, K, Hopfner, K.-P, Heck, A.J.R, Aebersold, R, Cramer, P.
登録日2011-08-23
公開日2011-09-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth.
Genes Dev., 25, 2011
3U23
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Atomic resolution crystal structure of the 2nd SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide from human RIN3
分子名称: 1,2-ETHANEDIOL, CD2-associated protein, Ras and Rab interactor 3
著者Simister, P.C, Rouka, E, Janning, M, Muniz, J.R.C, Kirsch, K.H, Knapp, S, von Delft, F, Filippakopoulos, P, Arrowsmith, C.H, Krojer, T, Edwards, A.M, Weigelt, J, Bountra, C, Feller, S.M, Structural Genomics Consortium (SGC)
登録日2011-09-30
公開日2011-12-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3).
J.Biol.Chem., 290, 2015
3VMR
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Crystal structure of Staphylococcus aureus membrane-bound transglycosylase in complex with moenomycin
分子名称: MOENOMYCIN, Monofunctional glycosyltransferase
著者Huang, C.Y, Shih, H.W, Lin, L.Y, Tien, Y.W, Cheng, T.J.R, Cheng, W.C, Wong, C.H, Ma, C.
登録日2011-12-15
公開日2012-04-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.688 Å)
主引用文献Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism
Proc.Natl.Acad.Sci.USA, 109, 2012
3VRF
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The crystal structure of hemoglobin from woolly mammoth in the carbonmonoxy forms
分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, ...
著者Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H.
登録日2012-04-09
公開日2012-11-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structures of haemoglobin from woolly mammoth in liganded and unliganded states.
Acta Crystallogr.,Sect.D, 68, 2012
3VMS
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Crystal structure of Staphylococcus aureus membrane-bound transglycosylase in complex with NBD-Lipid II
分子名称: Monofunctional glycosyltransferase
著者Huang, C.Y, Shih, H.W, Lin, L.Y, Tien, Y.W, Cheng, T.J.R, Cheng, W.C, Wong, C.H, Ma, C.
登録日2011-12-15
公開日2012-04-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.202 Å)
主引用文献Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism
Proc.Natl.Acad.Sci.USA, 109, 2012
3VUS
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Escherichia coli PgaB N-terminal domain
分子名称: ACETATE ION, MERCURY (II) ION, Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase, ...
著者Nishiyama, T, Noguchi, H, Yoshida, H, Park, S.-Y, Tame, J.R.H.
登録日2012-07-05
公開日2012-11-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The structure of the deacetylase domain of Escherichia coli PgaB, an enzyme required for biofilm formation: a circularly permuted member of the carbohydrate esterase 4 family
Acta Crystallogr.,Sect.D, 69, 2013
3WWF
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Crystal structure of the computationally designed Pizza2-SR protein
分子名称: pizza2sr-pb protein
著者Voet, A.R.D, Noguchi, H, Addy, C, Simoncini, D, Terada, D, Unzai, S, Park, S.Y, Zhang, K.Y.J, Tame, J.R.H.
登録日2014-06-17
公開日2014-10-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Computational design of a self-assembling symmetrical beta-propeller protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
3WW9
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Crystal structure of the computationally designed Pizza6 protein
分子名称: GLYCEROL, SULFATE ION, pizza6 protein
著者Voet, A.R.D, Noguchi, H, Addy, C, Simoncini, D, Terada, D, Unzai, S, Park, S.Y, Zhang, K.Y.J, Tame, J.R.H.
登録日2014-06-17
公開日2014-10-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Computational design of a self-assembling symmetrical beta-propeller protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
3WBA
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Rice Os3BGlu6 E178Q with Covalent Glucosyl Moiety from p-nitrophenyl glucopyranoside.
分子名称: Beta-glucosidase 6, GLYCEROL, alpha-D-glucopyranose
著者Sansenya, S, Hua, Y, Cairns, J.R.K.
登録日2013-05-14
公開日2013-09-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Enzymatic and structural characterization of hydrolysis of gibberellin A4 glucosyl ester by a rice beta-d-glucosidase
Arch.Biochem.Biophys., 537, 2013
3WBE
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Rice Os3BGlu6 Beta-Glucosidase E178Q mutant in a covalent complex with Glc from GA4GE.
分子名称: Beta-glucosidase 6, GLYCEROL, alpha-D-glucopyranose
著者Sansenya, S, Hua, Y, Cairns, J.R.K.
登録日2013-05-14
公開日2013-09-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Enzymatic and structural characterization of hydrolysis of gibberellin A4 glucosyl ester by a rice beta-d-glucosidase
Arch.Biochem.Biophys., 537, 2013
3WMU
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The structure of an anti-cancer lectin mytilec apo-form from the mussel Mytilus galloprovincialis
分子名称: GLYCEROL, Lectin
著者Terada, D, Kawai, F, Noguchi, H, Unzai, S, Park, S.-Y, Ozeki, Y, Tame, J.R.H.
登録日2013-11-27
公開日2014-12-03
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Crystal structure of MytiLec, a galactose-binding lectin from the mussel Mytilus galloprovincialis with cytotoxicity against certain cancer cell types
Sci Rep, 6, 2016
3WW7
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Crystal structure of the computationally designed Pizza2 protein
分子名称: GLYCEROL, Pizza2 protein
著者Voet, A.R.D, Noguchi, H, Addy, C, Simoncini, D, Terada, D, Unzai, S, Park, S.Y, Zhang, K.Y.J, Tame, J.R.H.
登録日2014-06-17
公開日2014-10-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.697 Å)
主引用文献Computational design of a self-assembling symmetrical beta-propeller protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
3WW8
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Crystal structure of the computationally designed Pizza3 protein
分子名称: GLYCEROL, Pizza3 protein, SULFATE ION
著者Voet, A.R.D, Noguchi, H, Addy, C, Simoncini, D, Terada, D, Unzai, S, Park, S.Y, Zhang, K.Y.J, Tame, J.R.H.
登録日2014-06-17
公開日2014-10-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.402 Å)
主引用文献Computational design of a self-assembling symmetrical beta-propeller protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
3ZRS
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X-ray crystal structure of a KirBac potassium channel highlights a mechanism of channel opening at the bundle-crossing gate.
分子名称: ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10, CHLORIDE ION, POTASSIUM ION
著者Bavro, V.N, De Zorzi, R, Schmidt, M.R, Muniz, J.R.C, Zubcevic, L, Sansom, M.S.P, Venien-Bryan, C, Tucker, S.J.
登録日2011-06-17
公開日2012-01-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structure of a Kirbac Potassium Channel with an Open Bundle Crossing Indicates a Mechanism of Channel Gating
Nat.Struct.Mol.Biol., 19, 2012
3X1W
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Ras-related protein Rap1B with GDP
分子名称: CADMIUM ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Noguchi, H, Ikegami, T, Akashi, S, Park, S.Y, Tame, J.R.H, Unzai, S.
登録日2014-12-02
公開日2015-06-03
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The structure and conformational switching of Rap1B
Biochem.Biophys.Res.Commun., 462, 2015
3X1Y
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Ras-related protein Rap1B(L9V) with GppNHp
分子名称: CADMIUM ION, GLYCEROL, MAGNESIUM ION, ...
著者Noguchi, H, Ikegami, T, Park, S.Y, Tame, J.R.H, Unzai, S.
登録日2014-12-02
公開日2015-06-03
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.168 Å)
主引用文献The structure and conformational switching of Rap1B
Biochem.Biophys.Res.Commun., 462, 2015
3X1X
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Ras-related protein Rap1B with GppNHp
分子名称: CADMIUM ION, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Noguchi, H, Ikegami, T, Park, S.Y, Tame, J.R.H, Unzai, S.
登録日2014-12-02
公開日2015-06-03
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献The structure and conformational switching of Rap1B
Biochem.Biophys.Res.Commun., 462, 2015
3X1Z
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Ras-related protein Rap1B(T65A) with GppNHp
分子名称: GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Noguchi, H, Ikegami, T, Park, S.Y, Tame, J.R.H, Unzai, S.
登録日2014-12-02
公開日2015-06-03
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献The structure and conformational switching of Rap1B
Biochem.Biophys.Res.Commun., 462, 2015
3ZW5
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Crystal structure of the human Glyoxalase domain-containing protein 5
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYOXALASE DOMAIN-CONTAINING PROTEIN 5, ...
著者Muniz, J.R.C, Kiyani, W, Froese, S, Vollmar, M, von Delft, F, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Yue, W.W.
登録日2011-07-28
公開日2011-08-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of the Human Glyoxalase Domain-Containing Protein 5
To be Published
3VMQ
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Crystal structure of Staphylococcus aureus membrane-bound transglycosylase: Apoenzyme
分子名称: MAGNESIUM ION, Monofunctional glycosyltransferase
著者Huang, C.Y, Shih, H.W, Lin, L.Y, Tien, Y.W, Cheng, T.J.R, Cheng, W.C, Wong, C.H, Ma, C.
登録日2011-12-15
公開日2012-04-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.518 Å)
主引用文献Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism
Proc.Natl.Acad.Sci.USA, 109, 2012
3VMT
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Crystal structure of Staphylococcus aureus membrane-bound transglycosylase in complex with a Lipid II analog
分子名称: MAGNESIUM ION, Monofunctional glycosyltransferase, [(2R,3R,4R,5S,6R)-4-[(2R)-1-[[(2S)-1-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxidanylidene-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethylamino]-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-propan-2-yl]oxy-3-acetamido-5-[(2S,3R,4R,5R,6R)-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl]oxy-6-(hydroxymethyl)oxan-2-yl] [oxidanyl(3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,14,18,22,26,30,34,38,42-undecaenoxy)phosphoryl] hydrogen phosphate
著者Huang, C.Y, Shih, H.W, Lin, L.Y, Tien, Y.W, Cheng, T.J.R, Cheng, W.C, Wong, C.H, Ma, C.
登録日2011-12-15
公開日2012-04-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.299 Å)
主引用文献Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism
Proc.Natl.Acad.Sci.USA, 109, 2012
3VRE
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The crystal structure of hemoglobin from woolly mammoth in the deoxy form
分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, PROTOPORPHYRIN IX CONTAINING FE
著者Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H.
登録日2012-04-09
公開日2012-11-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of haemoglobin from woolly mammoth in liganded and unliganded states.
Acta Crystallogr.,Sect.D, 68, 2012
3VRG
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The crystal structure of hemoglobin from woolly mammoth in the met form
分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H.
登録日2012-04-09
公開日2012-11-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structures of haemoglobin from woolly mammoth in liganded and unliganded states.
Acta Crystallogr.,Sect.D, 68, 2012
3ZTG
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Solution structure of the RING finger-like domain of Retinoblastoma Binding Protein-6 (RBBP6)
分子名称: E3 UBIQUITIN-PROTEIN LIGASE RBBP6, ZINC ION
著者Kappo, M.A, Ab, E, Atkinson, R.A, Faro, A, Muleya, V, Mulaudzi, T, Poole, J.O, McKenzie, J.M, Pugh, D.J.R.
登録日2011-07-07
公開日2011-12-07
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Solution Structure of the Ring Finger-Like Domain of Retinoblastoma Binding Protein-6 (Rbbp6) Suggests It Functions as a U-Box
J.Biol.Chem., 287, 2012

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