2XIO
| Structure of putative deoxyribonuclease TATDN1 isoform a | Descriptor: | 1,2-ETHANEDIOL, NICKEL (II) ION, PUTATIVE DEOXYRIBONUCLEASE TATDN1, ... | Authors: | Muniz, J.R.C, Cocking, R, Puranik, S, Krojer, T, Raynor, J, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Yue, W.W, Kavanagh, K.L, Oppermann, U. | Deposit date: | 2010-06-30 | Release date: | 2010-07-14 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | Structure of Putative Deoxyribonuclease Tatdn1 Isoform A To be Published
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2XDG
| Crystal structure of the extracellular domain of human growth hormone releasing hormone receptor. | Descriptor: | 1,2-ETHANEDIOL, GROWTH HORMONE-RELEASING HORMONE RECEPTOR, MAGNESIUM ION | Authors: | Pike, A.C.W, Quigley, A, Barr, A.J, Burgess Brown, N, Shrestha, L, Yang, J, Chaikuad, A, Vollmar, M, Muniz, J.R.C, von Delft, F, Edwards, A, Arrowsmith, C.H, Weigelt, J, Bountra, C, Carpenter, E.P. | Deposit date: | 2010-04-30 | Release date: | 2010-06-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structure of the Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor. To be Published
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3A3F
| Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae,complexed with novel beta-lactam (FMZ) | Descriptor: | (2R,4S)-5,5-dimethyl-2-[(1R)-2-oxo-1-({(2R)-2-[(2-oxoimidazolidin-1-yl)amino]-2-phenylacetyl}amino)ethyl]-1,3-thiazolidine-4-carboxylic acid, Penicillin-binding protein 4 | Authors: | Kawai, F, Roper, D.I, Park, S.-Y, Tame, J.R.H. | Deposit date: | 2009-06-12 | Release date: | 2009-12-22 | Last modified: | 2013-11-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of penicillin-binding proteins 4 and 5 from Haemophilus influenzae J.Mol.Biol., 396, 2010
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3A3I
| Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae, complexed with ampicillin (AIX) | Descriptor: | (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Penicillin-binding protein 4 | Authors: | Kawai, F, Roper, D.I, Park, S.-Y, Tame, J.R.H. | Deposit date: | 2009-06-12 | Release date: | 2009-12-22 | Last modified: | 2013-11-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of penicillin-binding proteins 4 and 5 from Haemophilus influenzae J.Mol.Biol., 396, 2010
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301D
| CAPTURING THE STRUCTURE OF A CATALYTIC RNA INTERMEDIATE: RNA HAMMERHEAD RIBOZYME, MG(II)-SOAKED | Descriptor: | MAGNESIUM ION, RNA HAMMERHEAD RIBOZYME | Authors: | Scott, W.G, Murray, J.B, Arnold, J.R.P, Stoddard, B.L, Klug, A. | Deposit date: | 1996-12-14 | Release date: | 1997-01-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme. Science, 274, 1996
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2XYN
| HUMAN ABL2 IN COMPLEX WITH AURORA KINASE INHIBITOR VX-680 | Descriptor: | CHLORIDE ION, CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE, SODIUM ION, ... | Authors: | Salah, E, Ugochukwu, E, Elkins, J.M, Barr, A.J, Shrestha, B, Savitsky, P, Mahajan, P, Muniz, J.R.C, Yue, W.W, Chaikuad, A, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2010-11-18 | Release date: | 2010-12-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Crystal Structures of Abl-Related Gene (Abl2) in Complex with Imatinib, Tozasertib (Vx-680), and a Type I Inhibitor of the Triazole Carbothioamide Class. J.Med.Chem., 54, 2011
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2XWC
| Crystal structure of the DNA binding domain of human TP73 refined at 1.8 A resolution | Descriptor: | GLYCEROL, TRIS(HYDROXYETHYL)AMINOMETHANE, TUMOUR PROTEIN P73, ... | Authors: | Canning, P, Zhang, Y, Vollmar, M, Krojer, T, Ugochukwu, E, Muniz, J.R.C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N. | Deposit date: | 2010-11-03 | Release date: | 2010-11-17 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structural Basis for Aspp2 Recognition by the Tumor Suppressor P73. J.Mol.Biol., 423, 2012
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2XD7
| Crystal structure of the macro domain of human core histone H2A | Descriptor: | CORE HISTONE MACRO-H2A.2 | Authors: | Vollmar, M, Phillips, C, Carpenter, E.P, Muniz, J.R.C, Krojer, T, Ugochukwu, E, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Gileadi, O. | Deposit date: | 2010-04-29 | Release date: | 2010-05-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Crystal Structure of the Macro Domain of Human Core Histone H2A To be Published
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2X64
| GLUTATHIONE-S-TRANSFERASE FROM XYLELLA FASTIDIOSA | Descriptor: | CHLORIDE ION, GLUTATHIONE, GLUTATHIONE-S-TRANSFERASE | Authors: | Muniz, J.R.C, Rodrigues, N.C, Bleicher, L, Travensolo, R.F, Garcia, W. | Deposit date: | 2010-02-14 | Release date: | 2010-03-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and Biophysical Characterization of the Recombinant Glutathione-S-Transferase from Xylella To be Published
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2WWW
| Crystal Structure of Methylmalonic Acidemia Type A Protein | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL, ... | Authors: | Muniz, J.R.C, Gileadi, C, Froese, D.S, Yue, W.W, Pike, A.C.W, von Delft, F, Kochan, G, Sethi, R, Chaikuad, A, Pilka, E, Picaud, S, Phillips, C, Guo, K, Krysztofinska, E, Bray, J, Burgess-Brown, N, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Gravel, R.A, Kavanagh, K.L, Oppermann, U. | Deposit date: | 2009-10-30 | Release date: | 2009-11-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Structures of the Human Gtpase Mmaa and Vitamin B12-Dependent Methylmalonyl-Coa Mutase and Insight Into Their Complex Formation. J.Biol.Chem., 285, 2010
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2WZK
| Structure of the Cul5 N-terminal domain at 2.05A resolution. | Descriptor: | 1,2-ETHANEDIOL, CULLIN-5 | Authors: | Muniz, J.R.C, Ayinampudi, V, Zhang, Y, Babon, J.J, Chaikuad, A, Krojer, T, Pike, A.C.W, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Bullock, A.N. | Deposit date: | 2009-11-30 | Release date: | 2009-12-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Molecular Architecture of the Ankyrin Socs Box Family of Cul5-Dependent E3 Ubiquitin Ligases J.Mol.Biol., 425, 2013
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2XDV
| Crystal Structure of the Catalytic Domain of FLJ14393 | Descriptor: | 1,2-ETHANEDIOL, CADMIUM ION, MANGANESE (II) ION, ... | Authors: | Krojer, T, Muniz, J.R.C, Ng, S.S, Pilka, E, Guo, K, Pike, A.C.W, Filippakopoulos, P, Knapp, S, Kavanagh, K.L, Gileadi, O, Bunkoczi, G, Yue, W.W, Niesen, F, Sobott, F, Fedorov, O, Savitsky, P, Kochan, G, Daniel, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Oppermann, U. | Deposit date: | 2010-05-07 | Release date: | 2010-05-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature, 510, 2014
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2XIK
| Structure of Human YSK1 (Yeast Sps1-Ste20-related Kinase 1) | Descriptor: | 1,2-ETHANEDIOL, 5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, SERINE/THREONINE PROTEIN KINASE 25 | Authors: | Muniz, J.R.C, Rellos, P, Ugochukwu, E, Vollmar, M, Allerston, C, Chaikuad, A, Savitsky, P, Berridge, G, Brenner, B, Elkins, J.M, Daga, N, Gileadi, O, Mahajan, P, Shrestha, B, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S. | Deposit date: | 2010-06-30 | Release date: | 2010-07-14 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structure of Human Ysk1 (Yeast Sps1-Ste20-Related Kinase 1) To be Published
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3A3J
| Crystal structures of penicillin binding protein 5 from Haemophilus influenzae | Descriptor: | PBP5, SULFATE ION | Authors: | Kawai, F, Roper, D.I, Park, S.-Y, Tame, J.R.H. | Deposit date: | 2009-06-12 | Release date: | 2009-12-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structures of penicillin-binding proteins 4 and 5 from Haemophilus influenzae J.Mol.Biol., 396, 2010
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3A3D
| Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae | Descriptor: | GLYCEROL, Penicillin-binding protein 4 | Authors: | Kawai, F, Roper, D.I, Park, S.-Y, Tame, J.R.H. | Deposit date: | 2009-06-12 | Release date: | 2009-12-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structures of penicillin-binding proteins 4 and 5 from Haemophilus influenzae J.Mol.Biol., 396, 2010
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2ZP9
| The Nature of the TRAP:Anti-TRAP complex | Descriptor: | TRYPTOPHAN, Transcription attenuation protein mtrB, Tryptophan RNA-binding attenuator protein-inhibitory protein, ... | Authors: | Watanabe, M, Heddle, J.G, Unzai, S, Akashi, S, Park, S.Y, Tame, J.R.H. | Deposit date: | 2008-07-08 | Release date: | 2009-02-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The nature of the TRAP-Anti-TRAP complex. Proc.Natl.Acad.Sci.USA, 106, 2009
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2ZD0
| Crystal structures and thermostability of mutant TRAP3 A5 (ENGINEERED TRAP) | Descriptor: | TRYPTOPHAN, Transcription attenuation protein mtrB | Authors: | Watanabe, M, Mishima, Y, Yamashita, I, Park, S.Y, Tame, J.R.H, Heddle, J.G. | Deposit date: | 2007-11-15 | Release date: | 2008-04-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Intersubunit linker length as a modifier of protein stability: crystal structures and thermostability of mutant TRAP. Protein Sci., 17, 2008
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2ZP8
| The Nature of the TRAP:Anti-TRAP complex | Descriptor: | TRYPTOPHAN, Transcription attenuation protein mtrB, Tryptophan RNA-binding attenuator protein-inhibitory protein, ... | Authors: | Watanabe, M, Heddle, J.G, Unzai, S, Akashi, S, Park, S.Y, Tame, J.R.H. | Deposit date: | 2008-07-08 | Release date: | 2009-02-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The nature of the TRAP-Anti-TRAP complex. Proc.Natl.Acad.Sci.USA, 106, 2009
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2ZCZ
| Crystal structures and thermostability of mutant TRAP3 A7 (ENGINEERED TRAP) | Descriptor: | TRYPTOPHAN, Transcription attenuation protein mtrB | Authors: | Watanabe, M, Mishima, Y, Yamashita, I, Park, S.Y, Tame, J.R.H, Heddle, J.G. | Deposit date: | 2007-11-15 | Release date: | 2008-04-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Intersubunit linker length as a modifier of protein stability: crystal structures and thermostability of mutant TRAP. Protein Sci., 17, 2008
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2YL2
| Crystal structure of human acetyl-CoA carboxylase 1, biotin carboxylase (BC) domain | Descriptor: | ACETYL-COA CARBOXYLASE 1 | Authors: | Muniz, J.R.C, Froese, D.S, Krysztofinska, E, Vollmar, M, Beltrami, A, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Yue, W.W, Oppermann, U. | Deposit date: | 2011-05-31 | Release date: | 2011-06-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of Human Acetyl-Coa Carboxylase 1, Biotin Carboxylase (Bc) Domain To be Published
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2YDX
| Crystal structure of human S-adenosylmethionine synthetase 2, beta subunit | Descriptor: | 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE, CALCIUM ION, METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA, ... | Authors: | Muniz, J.R.C, Shafqat, N, Pike, A.C.W, Yue, W.W, Vollmar, M, Papagriogriou, V, Roos, A, Gileadi, O, von Delft, F, Kavanagh, K.L, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Oppermann, U. | Deposit date: | 2011-03-25 | Release date: | 2011-04-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Insight Into S-Adenosylmethionine Biosynthesis from the Crystal Structures of the Human Methionine Adenosyltransferase Catalytic and Regulatory Subunits. Biochem.J., 452, 2013
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3AEH
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3AK5
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300D
| CAPTURING THE STRUCTURE OF A CATALYTIC RNA INTERMEDIATE: RNA HAMMERHEAD RIBOZYME, MN(II)-SOAKED | Descriptor: | MANGANESE (II) ION, RNA HAMMERHEAD RIBOZYME | Authors: | Scott, W.G, Murray, J.B, Arnold, J.R.P, Stoddard, B.L, Klug, A. | Deposit date: | 1996-12-14 | Release date: | 1997-01-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme. Science, 274, 1996
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3A3E
| Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae, complexed with novel beta-lactam (CMV) | Descriptor: | (2R,4S)-2-[(1R)-1-({(2R)-2-[(4-ethyl-2,3-dioxopiperazin-1-yl)amino]-2-phenylacetyl}amino)-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Penicillin-binding protein 4 | Authors: | Kawai, F, Roper, D.I, Park, S.-Y, Tame, J.R.H. | Deposit date: | 2009-06-12 | Release date: | 2009-12-22 | Last modified: | 2013-11-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of penicillin-binding proteins 4 and 5 from Haemophilus influenzae J.Mol.Biol., 396, 2010
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