7MH0
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![BU of 7mh0 by Molmil](/molmil-images/mine/7mh0) | Human CTPS1 bound to CTP | 分子名称: | CTP synthase 1, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION | 著者 | Lynch, E.M, Kollman, J.M. | 登録日 | 2021-04-14 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
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7MIU
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![BU of 7miu by Molmil](/molmil-images/mine/7miu) | Mouse CTPS2 bound to inhibitor R80 | 分子名称: | CTP synthase 2, GLUTAMINE, MAGNESIUM ION, ... | 著者 | Lynch, E.M, Dimattia, M.A, Kollman, J.M. | 登録日 | 2021-04-17 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
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7MIH
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![BU of 7mih by Molmil](/molmil-images/mine/7mih) | Human CTPS2 bound to inhibitor R80 | 分子名称: | CTP synthase 2, GLUTAMINE, MAGNESIUM ION, ... | 著者 | Lynch, E.M, Dimattia, M.A, Kollman, J.M. | 登録日 | 2021-04-16 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
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7MON
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![BU of 7mon by Molmil](/molmil-images/mine/7mon) | Structure of human RIPK3-MLKL complex | 分子名称: | Mixed lineage kinase domain-like protein, N-[4-({2-[(cyclopropanecarbonyl)amino]pyridin-4-yl}oxy)-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 3 | 著者 | Meng, Y, Davies, K.A, Czabotar, P.E, Murphy, J.M. | 登録日 | 2021-05-03 | 公開日 | 2021-11-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis. Nat Commun, 12, 2021
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6DDA
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![BU of 6dda by Molmil](/molmil-images/mine/6dda) | Nurr1 Covalently Modified by a Dopamine Metabolite | 分子名称: | 5-hydroxy-1,2-dihydro-6H-indol-6-one, BROMIDE ION, Nuclear receptor subfamily 4 group A member 2, ... | 著者 | Bruning, J.M, Wang, Y, Otrabella, F, Boxue, T, Liu, H, Bhattacharya, P, Guo, S, Holton, J.M, Fletterick, R.J, Jacobson, M.P, England, P.M. | 登録日 | 2018-05-09 | 公開日 | 2019-03-20 | 最終更新日 | 2019-11-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite. Cell Chem Biol, 26, 2019
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2CBP
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![BU of 2cbp by Molmil](/molmil-images/mine/2cbp) | |
7NFR
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![BU of 7nfr by Molmil](/molmil-images/mine/7nfr) | Fujian capmidlink domain in complex with Nb8194 | 分子名称: | GLYCEROL, NB8194, Polymerase basic protein 2, ... | 著者 | Keown, J.R, Grimes, J.M, Fodor, E. | 登録日 | 2021-02-07 | 公開日 | 2021-12-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NHX
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![BU of 7nhx by Molmil](/molmil-images/mine/7nhx) | 1918 H1N1 Viral influenza polymerase heterotrimer - full transcriptase (Class1) | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-11 | 公開日 | 2021-12-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NIS
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![BU of 7nis by Molmil](/molmil-images/mine/7nis) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8192 core | 分子名称: | Nanobody8192 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-13 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (5.96 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NK6
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![BU of 7nk6 by Molmil](/molmil-images/mine/7nk6) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8204 | 分子名称: | Nb8204, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-17 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (6.72 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NK1
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![BU of 7nk1 by Molmil](/molmil-images/mine/7nk1) | 1918 Influenza virus polymerase heterotirmer in complex with vRNA promoters and Nb8201 | 分子名称: | Nanobody8201, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-17 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (4.22 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NKI
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![BU of 7nki by Molmil](/molmil-images/mine/7nki) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8209 core | 分子名称: | Nb8209, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-18 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (4.67 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NJ7
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![BU of 7nj7 by Molmil](/molmil-images/mine/7nj7) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8200 core | 分子名称: | Nb8200 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-16 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (4.82 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NKA
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![BU of 7nka by Molmil](/molmil-images/mine/7nka) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8206 | 分子名称: | NB8206, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-17 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (4.07 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NKR
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![BU of 7nkr by Molmil](/molmil-images/mine/7nkr) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8210 | 分子名称: | Nb8210, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-18 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NFQ
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![BU of 7nfq by Molmil](/molmil-images/mine/7nfq) | Fujian capmidlink domain in complex with Nb8193 | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Nb8193, ... | 著者 | Keown, J.R, Grimes, J.M, Fodor, E. | 登録日 | 2021-02-07 | 公開日 | 2021-12-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NHA
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![BU of 7nha by Molmil](/molmil-images/mine/7nha) | 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease and priming loop ordered (Class2a) | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-10 | 公開日 | 2021-12-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NIK
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![BU of 7nik by Molmil](/molmil-images/mine/7nik) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8189 core | 分子名称: | Nanobody8189 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-12 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NI0
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![BU of 7ni0 by Molmil](/molmil-images/mine/7ni0) | 1918 H1N1 Viral influenza polymerase heterotrimer - Replicase (class 3) | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-11 | 公開日 | 2021-12-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NJ5
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![BU of 7nj5 by Molmil](/molmil-images/mine/7nj5) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8199 core | 分子名称: | Nb8199 Core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-16 | 公開日 | 2021-12-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.63 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NKC
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![BU of 7nkc by Molmil](/molmil-images/mine/7nkc) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8207 | 分子名称: | Nb8207, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-17 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (4.46 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NIR
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![BU of 7nir by Molmil](/molmil-images/mine/7nir) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8191 core | 分子名称: | Nanobody8191 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-13 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NK2
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![BU of 7nk2 by Molmil](/molmil-images/mine/7nk2) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8202 core | 分子名称: | Nanobody8202, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-17 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (4.84 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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2YOI
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![BU of 2yoi by Molmil](/molmil-images/mine/2yoi) | Crystal Structure of Ancestral Thioredoxin Relative to Last Eukaryotes Common Ancestor (LECA) from the Precambrian Period | 分子名称: | ACETATE ION, CHLORIDE ION, LECA THIOREDOXIN, ... | 著者 | Gavira, J.A, Ingles-Prieto, A, Ibarra-Molero, B, Sanchez-Ruiz, J.M. | 登録日 | 2012-10-24 | 公開日 | 2013-08-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Conservation of protein structure over four billion years. Structure, 21, 2013
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7NFT
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![BU of 7nft by Molmil](/molmil-images/mine/7nft) | |