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PDB: 5587 件

1HXS
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CRYSTAL STRUCTURE OF MAHONEY STRAIN OF POLIOVIRUS AT 2.2A RESOLUTION
分子名称: GENOME POLYPROTEIN, COAT PROTEIN VP1, COAT PROTEIN VP2, ...
著者Miller, S.T, Hogle, J.M, Filman, D.J.
登録日2001-01-16
公開日2002-01-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Ab initio phasing of high-symmetry macromolecular complexes: successful phasing of authentic poliovirus data to 3.0 A resolution.
J.Mol.Biol., 307, 2001
5EZT
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Peracetylated Bovine Carbonic Anhydrase II
分子名称: Carbonic anhydrase 2, ZINC ION
著者Whitesides, G.M, Kang, K, Choi, J.-M, Fox, J.M.
登録日2015-11-26
公開日2016-07-20
最終更新日2016-07-27
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Acetylation of Surface Lysine Groups of a Protein Alters the Organization and Composition of Its Crystal Contacts.
J.Phys.Chem.B, 120, 2016
5DS3
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Crystal structure of constitutively active PARP-1
分子名称: 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one, PENTAETHYLENE GLYCOL, Poly [ADP-ribose] polymerase 1, ...
著者Langelier, M.F, Pascal, J.M.
登録日2015-09-16
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain.
Mol.Cell, 60, 2015
5DSY
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Crystal structure of constitutively active PARP-2
分子名称: 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide, Poly [ADP-ribose] polymerase 2
著者Riccio, A.A, Pascal, J.M.
登録日2015-09-17
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain.
Mol.Cell, 60, 2015
7OI2
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SaFtsz complexed with GDP (NaCl purification)
分子名称: 1,2-ETHANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ...
著者Fernandez-Tornero, C, Ruiz, F.M, Andreu Morales, J.M.
登録日2021-05-11
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
4JCJ
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Crystal structure of Isl1 LIM domains with Ldb1 LIM-interaction domain
分子名称: Insulin gene enhancer protein ISL-1,LIM domain-binding protein 1, ZINC ION
著者Gadd, M.S, Jacques, D.A, Guss, J.M, Matthews, J.M.
登録日2013-02-21
公開日2013-06-19
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra- and intermolecular interactions.
J.Biol.Chem., 288, 2013
6PCY
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BU of 6pcy by Molmil
CRYSTAL STRUCTURE ANALYSES OF REDUCED (CUI) POPLAR PLASTOCYANIN AT SIX PH VALUES
分子名称: COPPER (II) ION, PLASTOCYANIN
著者Guss, J.M, Freeman, H.C.
登録日1986-09-02
公開日1987-01-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure analyses of reduced (CuI) poplar plastocyanin at six pH values.
J.Mol.Biol., 192, 1986
2BF3
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Crystal structure of a toluene 4-monooxygenase catalytic effector protein variant missing ten N-terminal residues (delta-N10 T4moD)
分子名称: HEPTANE-1,2,3-TRIOL, TOLUENE-4-MONOOXYGENASE SYSTEM PROTEIN D
著者Lountos, G.T, Mitchell, K.H, Studts, J.M, Fox, B.G, Orville, A.M.
登録日2004-12-03
公開日2005-05-19
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal Structures and Functional Studies of T4Mod, the Toluene 4-Monooxygenase Catalytic Effector Protein
Biochemistry, 44, 2005
2BF5
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Crystal structure of a toluene 4-monooxygenase catalytic effector protein variant missing four N-terminal residues (delta-N4 T4moD)
分子名称: TOLUENE-4-MONOOXYGENASE SYSTEM PROTEIN D
著者Lountos, G.T, Mitchell, K.H, Studts, J.M, Fox, B.G, Orville, A.M.
登録日2004-12-03
公開日2005-05-19
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Crystal Structures and Functional Studies of T4Mod, the Toluene 4-Monooxygenase Catalytic Effector Protein
Biochemistry, 44, 2005
2BF2
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Crystal structure of native toluene-4-monooxygenase catalytic effector protein, T4moD
分子名称: TOLUENE-4-MONOOXYGENASE SYSTEM PROTEIN D
著者Lountos, G.T, Mitchell, K.H, Studts, J.M, Fox, B.G, Orville, A.M.
登録日2004-12-03
公開日2005-05-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures and Functional Studies of T4Mod, the Toluene 4-Monooxygenase Catalytic Effector Protein
Biochemistry, 44, 2005
6PTL
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Structure of the self-association domain of the chromatin looping factor LDB1
分子名称: LIM domain-binding protein 1
著者Macindoe, I, Silva, A, Guss, J.M, Mackay, J.P, Matthews, J.M.
登録日2019-07-16
公開日2020-07-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the self-association domain of the chromatin looping factor LDB1
To Be Published
4YHF
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Bruton's tyrosine kinase in complex with a t-butyl cyanoacrylamide inhibitor
分子名称: (2S)-2-({(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}carbonyl)-4,4-dimethylpentanenitrile, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Paavilainen, V.O, McFarland, J.M, Taunton, J.
登録日2015-02-27
公開日2015-05-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Prolonged and tunable residence time using reversible covalent kinase inhibitors.
Nat.Chem.Biol., 11, 2015
4YNQ
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TREX1-dsDNA complex
分子名称: DNA (24-MER), DNA (5'-D(P*GP*TP*GP*CP*TP*GP*AP*CP*GP*TP*CP*AP*GP*CP*AP*CP*GP*AP*CP*G)-3'), MAGNESIUM ION, ...
著者Fye, J.M, Harvey, S, Perrino, F.W, Hollis, T.
登録日2015-03-10
公開日2015-05-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease.
Proc.Natl.Acad.Sci.USA, 112, 2015
8FOZ
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Human IMPDH2 mutant - L245P, treated with ATP, IMP, and NAD+; filament assembly interface reconstruction
分子名称: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者O'Neill, A.G, Kollman, J.M.
登録日2023-01-03
公開日2023-04-19
最終更新日2023-08-09
実験手法ELECTRON MICROSCOPY (2 Å)
主引用文献Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
8FUZ
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BU of 8fuz by Molmil
Human IMPDH2 mutant - L245P, treated with GTP, ATP, IMP, and NAD+; filament assembly interface reconstruction
分子名称: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者O'Neill, A.G, Kollman, J.M.
登録日2023-01-18
公開日2023-04-19
最終更新日2023-08-09
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
6IC4
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Cryo-EM structure of the A. baumannii MLA complex at 8.7 A resolution
分子名称: ABC transporter ATP-binding protein, ABC transporter permease, Toluene tolerance efflux transporter (ABC superfamily, ...
著者Bergeron, J.R, Kollman, J.M.
登録日2018-12-02
公開日2019-01-23
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (8.7 Å)
主引用文献The Acinetobacter baumannii Mla system and glycerophospholipid transport to the outer membrane.
Elife, 8, 2019
6I2D
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Crystal Structure of the Protein-Kinase A catalytic subunit from Cricetulus Griseus in complex with compounds RKp182 and RKp117
分子名称: UPF0418 protein FAM164A, [2-[(4-isoquinolin-5-ylsulfonyl-1,4-diazepan-1-yl)methyl]phenyl]boronic acid, cAMP-dependent protein kinase catalytic subunit alpha
著者Mueller, J.M, Heine, A, Klebe, G.
登録日2018-11-01
公開日2019-05-15
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage
Acs Omega, 2019
6I7M
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Influenza A nucleoprotein docked into 3D helical structure of the wild type ribonucleoprotein complex obtained using cryoEM. Conformation 4.
分子名称: Nucleoprotein
著者Coloma, R, Arranz, R, de la Rosa-Trevin, J.M, Sorzano, C.O.S, Carlero, D, Ortin, J, Martin-Benito, J.
登録日2018-11-16
公開日2020-02-12
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Structural insights into influenza A virus ribonucleoproteins reveal a processive helical track as transcription mechanism.
Nat Microbiol, 5, 2020
6I2A
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Crystal Structure of the Protein-Kinase A catalytic subunit from Cricetulus Griseus in complex with compounds RKp153 and Fasudil
分子名称: 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE, UPF0418 protein FAM164A, beta-D-ribopyranose, ...
著者Mueller, J.M, Heine, A, Klebe, G.
登録日2018-11-01
公開日2019-05-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage
Acs Omega, 2019
6IA2
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Crystal structure of a self-complementary RNA duplex recognized by Com
分子名称: CHLORIDE ION, RNA (5'-R(*AP*GP*AP*GP*AP*AP*CP*CP*CP*GP*GP*AP*GP*UP*UP*CP*CP*CP*U)-3'), SULFATE ION
著者Nowacka, M, Fernandes, H, Kiliszek, A, Bernat, A, Lach, G, Bujnicki, J.M.
登録日2018-11-26
公開日2019-03-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Specific interaction of zinc finger protein Com with RNA and the crystal structure of a self-complementary RNA duplex recognized by Com.
Plos One, 14, 2019
2VXY
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The structure of FTsZ from Bacillus subtilis at 1.7A resolution
分子名称: CELL DIVISION PROTEIN FTSZ, CITRIC ACID, POTASSIUM ION
著者Barynin, V.V, Baker, P.J, Rice, D.W, Sedelnikova, S.E, Haydon, D.J, Stokes, N.R, Ure, R, Galbraith, G, Bennett, J.M, Brown, D.R, Heal, J.R, Sheridan, J.M, Aiwale, S.T, Chauhan, P.K, Srivastava, A, Taneja, A, Collins, I, Errington, J, Czaplewski, L.G.
登録日2008-07-15
公開日2008-09-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献An Inhibitor of Ftsz with Potent and Selective Anti-Staphylococcal Activity.
Science, 321, 2008
6I7B
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BU of 6i7b by Molmil
Influenza A nucleoprotein docked into 3D helical structure of the wild type ribonucleoprotein complex obtained using cryoEM. Conformation 3.
分子名称: Nucleoprotein
著者Coloma, R, Arranz, R, de la Rosa-Trevin, J.M, Sorzano, C.O.S, Carlero, D, Ortin, J, Martin-Benito, J.
登録日2018-11-16
公開日2020-02-19
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Structural insights into influenza A virus ribonucleoproteins reveal a processive helical track as transcription mechanism.
Nat Microbiol, 5, 2020
8JJW
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Crystal structure of QG-hNTAQ1 C28S
分子名称: MAGNESIUM ION, Protein N-terminal glutamine amidohydrolase
著者Kang, J.M, Han, B.W.
登録日2023-05-31
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural study for substrate recognition of human N-terminal glutamine amidohydrolase 1 in the arginine N-degron pathway.
Protein Sci., 33, 2024
8JJY
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Crystal structure of QN-hNTAQ1 C28S
分子名称: Protein N-terminal glutamine amidohydrolase
著者Kang, J.M, Han, B.W.
登録日2023-05-31
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structural study for substrate recognition of human N-terminal glutamine amidohydrolase 1 in the arginine N-degron pathway.
Protein Sci., 33, 2024
8JK2
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Crystal structure of QF-hNTAQ1 C28S
分子名称: Protein N-terminal glutamine amidohydrolase
著者Kang, J.M, Han, B.W.
登録日2023-05-31
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.742 Å)
主引用文献Structural study for substrate recognition of human N-terminal glutamine amidohydrolase 1 in the arginine N-degron pathway.
Protein Sci., 33, 2024

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