1L8Q
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4CS8
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![BU of 4cs8 by Molmil](/molmil-images/mine/4cs8) | Crystal structure of the asymmetric human metapneumovirus M2-1 tetramer, form 2 | 分子名称: | M2-1, ZINC ION | 著者 | Leyrat, C, Renner, M, Harlos, K, Grimes, J.M. | 登録日 | 2014-03-05 | 公開日 | 2014-05-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Drastic Changes in Conformational Dynamics of the Antiterminator M2-1 Regulate Transcription Efficiency in Pneumovirinae. Elife, 3, 2014
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2FO0
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![BU of 2fo0 by Molmil](/molmil-images/mine/2fo0) | Organization of the SH3-SH2 Unit in Active and Inactive Forms of the c-Abl Tyrosine Kinase | 分子名称: | 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, GLYCEROL, MYRISTIC ACID, ... | 著者 | Nagar, B, Hantschel, O, Seeliger, M, Davies, J.M, Weis, W.I, Superti-Furga, G, Kuriyan, J. | 登録日 | 2006-01-12 | 公開日 | 2006-03-21 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase. Mol.Cell, 21, 2006
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3MJM
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![BU of 3mjm by Molmil](/molmil-images/mine/3mjm) | His257Ala mutant of dihydroorotase from E. coli | 分子名称: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | 著者 | Ernberg, K.E, Guss, J.M, Lee, M, Maher, M.J. | 登録日 | 2010-04-13 | 公開日 | 2011-03-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | His257Ala mutant of dihydroorotase from E. coli To be Published
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1PV4
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4CI6
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![BU of 4ci6 by Molmil](/molmil-images/mine/4ci6) | Mechanisms of crippling actin-dependent phagocytosis by YopO | 分子名称: | ACTIN, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | 著者 | Lee, W.L, Grimes, J.M, Robinson, R.C. | 登録日 | 2013-12-06 | 公開日 | 2015-01-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.651 Å) | 主引用文献 | Yersinia Effector Yopo Uses Actin as Bait to Phosphorylate Proteins that Regulate Actin Polymerization. Nat.Struct.Mol.Biol., 22, 2015
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1PVO
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4CS7
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![BU of 4cs7 by Molmil](/molmil-images/mine/4cs7) | Crystal structure of the asymmetric human metapneumovirus M2-1 tetramer, form 1 | 分子名称: | M2-1, ZINC ION | 著者 | Leyrat, C, Renner, M, Harlos, K, Grimes, J.M. | 登録日 | 2014-03-05 | 公開日 | 2014-05-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Drastic Changes in Conformational Dynamics of the Antiterminator M2-1 Regulate Transcription Efficiency in Pneumovirinae. Elife, 3, 2014
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3FZV
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![BU of 3fzv by Molmil](/molmil-images/mine/3fzv) | Crystal structure of PA01 protein, putative LysR family transcriptional regulator from Pseudomonas aeruginosa | 分子名称: | Probable transcriptional regulator, SULFATE ION | 著者 | Knapik, A.A, Tkaczuk, K.L, Chruszcz, M, Wang, S, Zimmerman, M.D, Cymborowski, M, Skarina, T, Kagan, O, Savchenko, A, Edwards, A.M, Joachimiak, A, Bujnicki, J.M, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2009-01-26 | 公開日 | 2009-03-10 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Crystal structure of PA01 protein, putative LysR family transcriptional regulator from Pseudomonas aeruginosa To be Published
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3DBI
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![BU of 3dbi by Molmil](/molmil-images/mine/3dbi) | CRYSTAL STRUCTURE OF SUGAR-BINDING TRANSCRIPTIONAL REGULATOR (LACI FAMILY) FROM ESCHERICHIA COLI COMPLEXED WITH PHOSPHATE | 分子名称: | GLYCEROL, PHOSPHATE ION, SUGAR-BINDING TRANSCRIPTIONAL REGULATOR, ... | 著者 | Patskovsky, Y, Ozyurt, S, Freeman, J, Wu, B, Maletic, M, Koss, J, Wasserman, S.R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2008-06-01 | 公開日 | 2008-07-01 | 最終更新日 | 2021-02-03 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal Structure of Sugar-Binding Transcriptional Regulator (LacI Family) from Escherichia Coli Complexed with Phosphate. To be Published
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2FQQ
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![BU of 2fqq by Molmil](/molmil-images/mine/2fqq) | Crystal structure of human caspase-1 (Cys285->Ala, Cys362->Ala, Cys364->Ala, Cys397->Ala) in complex with 1-methyl-3-trifluoromethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid (2-mercapto-ethyl)-amide | 分子名称: | 1-METHYL-3-TRIFLUOROMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)-AMIDE, Caspase-1 | 著者 | Scheer, J.M, Wells, J.A, Romanowski, M.J. | 登録日 | 2006-01-18 | 公開日 | 2006-05-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | A common allosteric site and mechanism in caspases Proc.Natl.Acad.Sci.USA, 103, 2006
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3M2M
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3DGP
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![BU of 3dgp by Molmil](/molmil-images/mine/3dgp) | Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2 | 分子名称: | RNA polymerase II transcription factor B subunit 2, RNA polymerase II transcription factor B subunit 5 | 著者 | Kainov, D.E, Cavarelli, J, Egly, J.M, Poterszman, A. | 登録日 | 2008-06-14 | 公開日 | 2008-08-19 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for group A trichothiodystrophy Nat.Struct.Mol.Biol., 15, 2008
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3FXG
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![BU of 3fxg by Molmil](/molmil-images/mine/3fxg) | Crystal structure of rhamnonate dehydratase from Gibberella zeae complexed with Mg | 分子名称: | MAGNESIUM ION, Rhamnonate dehydratase | 著者 | Fedorov, A.A, Fedorov, E.V, Sauder, J.M, Burley, S.K, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2009-01-20 | 公開日 | 2009-02-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of rhamnonate dehydratase from Gibberella zeae complexed with Mg To be Published
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1S0Z
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![BU of 1s0z by Molmil](/molmil-images/mine/1s0z) | Crystal structure of the VDR LBD complexed to seocalcitol. | 分子名称: | SEOCALCITOL, Vitamin D3 receptor | 著者 | Tocchini-Valentini, G, Rochel, N, Wurtz, J.M, Moras, D. | 登録日 | 2004-01-05 | 公開日 | 2004-04-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification. J.Med.Chem., 47, 2004
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4CS9
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![BU of 4cs9 by Molmil](/molmil-images/mine/4cs9) | Crystal structure of the asymmetric human metapneumovirus M2-1 tetramer bound to adenosine monophosphate | 分子名称: | ADENOSINE MONOPHOSPHATE, M2-1, ZINC ION | 著者 | Leyrat, C, Renner, M, Harlos, K, Grimes, J.M. | 登録日 | 2014-03-05 | 公開日 | 2014-05-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Drastic Changes in Conformational Dynamics of the Antiterminator M2-1 Regulate Transcription Efficiency in Pneumovirinae. Elife, 3, 2014
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1S1Q
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![BU of 1s1q by Molmil](/molmil-images/mine/1s1q) | TSG101(UEV) domain in complex with Ubiquitin | 分子名称: | ACETIC ACID, COPPER (II) ION, SULFATE ION, ... | 著者 | Sundquist, W.I, Schubert, H.L, Kelly, B.N, Hill, G.C, Holton, J.M, Hill, C.P. | 登録日 | 2004-01-07 | 公開日 | 2004-05-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Ubiquitin recognition by the human TSG101 protein Mol.Cell, 13, 2004
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1MM3
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![BU of 1mm3 by Molmil](/molmil-images/mine/1mm3) | Solution structure of the 2nd PHD domain from Mi2b with C-terminal loop replaced by corresponding loop from WSTF | 分子名称: | Mi2-beta(Chromodomain helicase-DNA-binding protein 4) and transcription factor WSTF, ZINC ION | 著者 | Kwan, A.H.Y, Gell, D.A, Verger, A, Crossley, M, Matthews, J.M, Mackay, J.P. | 登録日 | 2002-09-02 | 公開日 | 2003-07-22 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Engineering a Protein Scaffold from a PHD Finger structure, 11, 2003
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4BIJ
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![BU of 4bij by Molmil](/molmil-images/mine/4bij) | Threading model of T7 large terminase | 分子名称: | DNA MATURASE B | 著者 | Dauden, M.I, Martin-Benito, J, Sanchez-Ferrero, J.C, Pulido-Cid, M, Valpuesta, J.M, Carrascosa, J.L. | 登録日 | 2013-04-10 | 公開日 | 2013-05-08 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (16 Å) | 主引用文献 | Large Terminase Conformational Change Induced by Connector Binding in Bacteriophage T7 J.Biol.Chem., 288, 2013
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3K4H
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![BU of 3k4h by Molmil](/molmil-images/mine/3k4h) | CRYSTAL STRUCTURE OF putative transcriptional regulator LacI from Bacillus cereus subsp. cytotoxis NVH 391-98 | 分子名称: | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, putative transcriptional regulator | 著者 | Malashkevich, V.N, Toro, R, Morano, C, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2009-10-05 | 公開日 | 2009-11-10 | 最終更新日 | 2021-02-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | CRYSTAL STRUCTURE OF putative transcriptional regulator LacI from Bacillus cereus subsp. cytotoxis NVH 391-98 To be Published
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1S83
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![BU of 1s83 by Molmil](/molmil-images/mine/1s83) | PORCINE TRYPSIN COMPLEXED WITH 4-AMINO PROPANOL | 分子名称: | 4-HYDROXYBUTAN-1-AMINIUM, CALCIUM ION, MAGNESIUM ION, ... | 著者 | Transue, T.R, Krahn, J.M, Gabel, S.A, DeRose, E.F, London, R.E. | 登録日 | 2004-01-30 | 公開日 | 2004-03-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | X-ray and NMR characterization of covalent complexes of trypsin, borate, and alcohols. Biochemistry, 43, 2004
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3HVD
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![BU of 3hvd by Molmil](/molmil-images/mine/3hvd) | The Protective Antigen Component of Anthrax Toxin Forms Functional Octameric Complexes | 分子名称: | CALCIUM ION, Protective antigen | 著者 | Kintzer, A.F, Dong, K.C, Berger, J.M, Krantz, B.A. | 登録日 | 2009-06-15 | 公開日 | 2009-08-25 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.209 Å) | 主引用文献 | The protective antigen component of anthrax toxin forms functional octameric complexes. J.Mol.Biol., 392, 2009
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3HY9
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![BU of 3hy9 by Molmil](/molmil-images/mine/3hy9) | Crystal Structure of the Catalytic Domain of ADAMTS-5 in Complex with an Amino-2-indanol compound | 分子名称: | (3R)-N~2~-(cyclopropylmethyl)-N~1~-hydroxy-3-(3-hydroxybenzyl)-N~4~-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-L-aspartamide, CALCIUM ION, Catalytic Domain of ADAMTS-5, ... | 著者 | Shieh, H.-S, Williams, J.M, Caspers, N, Mathis, K.J, Tortorella, M.D, Tomasselli, A. | 登録日 | 2009-06-22 | 公開日 | 2009-07-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Structural and inhibition analysis reveals the mechanism of selectivity of a series of aggrecanase inhibitors J.Biol.Chem., 284, 2009
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8ETR
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![BU of 8etr by Molmil](/molmil-images/mine/8etr) | CryoEM Structure of NLRP3 NACHT domain in complex with G2394 | 分子名称: | (6S,8R)-N-[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl]-6-(methylamino)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-sulfonamide, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Murray, J.M, Johnson, M.C. | 登録日 | 2022-10-17 | 公開日 | 2022-11-02 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Overcoming Preclinical Safety Obstacles to Discover ( S )- N -((1,2,3,5,6,7-Hexahydro- s -indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5 H -pyrazolo[5,1- b ][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor. J.Med.Chem., 65, 2022
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1M0I
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![BU of 1m0i by Molmil](/molmil-images/mine/1m0i) | Crystal Structure of Bacteriophage T7 Endonuclease I with a Wild-Type Active Site | 分子名称: | SULFATE ION, endodeoxyribonuclease I | 著者 | Hadden, J.M, Declais, A.C, Phillips, S.E, Lilley, D.M. | 登録日 | 2002-06-13 | 公開日 | 2002-12-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Metal ions bound at the active site of the junction-resolving enzyme T7 endonuclease I Embo J., 21, 2002
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