4M0A
 
 | | Human DNA Polymerase Mu post-catalytic complex | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA-directed DNA/RNA polymerase mu, ... | | 著者 | Moon, A.F, Pryor, J.M, Ramsden, D.A, Kunkel, T.A, Bebenek, K, Pedersen, L.C. | | 登録日 | 2013-08-01 | | 公開日 | 2014-02-05 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Sustained active site rigidity during synthesis by human DNA polymerase mu.
Nat.Struct.Mol.Biol., 21, 2014
|
|
4M21
 | | Crystal Structure of small molecule acrylamide 11 covalently bound to K-Ras G12C | | 分子名称: | 1-(4-{[(4,5-dichloro-2-methoxyphenyl)amino]acetyl}piperazin-1-yl)propan-1-one, GUANOSINE-5'-DIPHOSPHATE, K-Ras GTPase | | 著者 | Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M. | | 登録日 | 2013-08-05 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
|
|
2B3V
 | | Spermine spermidine acetyltransferase in complex with acetylcoa, K26R mutant | | 分子名称: | ACETYL COENZYME *A, Diamine acetyltransferase 1 | | 著者 | Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2005-09-21 | | 公開日 | 2006-01-17 | | 最終更新日 | 2021-02-03 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target.
Proc.Natl.Acad.Sci.USA, 103, 2006
|
|
2B3U
 | | Human Spermine spermidine acetyltransferase K26R mutant | | 分子名称: | Diamine acetyltransferase 1, SULFATE ION | | 著者 | Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2005-09-21 | | 公開日 | 2006-01-17 | | 最終更新日 | 2021-02-03 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target.
Proc.Natl.Acad.Sci.USA, 103, 2006
|
|
2B4B
 | | SSAT+COA+BE-3-3-3, K26R mutant | | 分子名称: | COENZYME A, Diamine acetyltransferase 1, N-ETHYL-N-[3-(PROPYLAMINO)PROPYL]PROPANE-1,3-DIAMINE | | 著者 | Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2005-09-23 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-05-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target
Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
2B6F
 | | Solution structure of human sulfiredoxin (SRX) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Sulfiredoxin | | 著者 | Gruschus, J.M, Lee, D.-Y, Ferretti, J.A, Rhee, S.G. | | 登録日 | 2005-10-01 | | 公開日 | 2006-09-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mutagenesis and Modeling of the Peroxiredoxin (Prx) Complex with the NMR Structure of ATP-Bound Human Sulfiredoxin Implicate Aspartate 187 of Prx I as the Catalytic Residue in ATP Hydrolysis
Biochemistry, 45, 2006
|
|
2B8Q
 | | X-ray structure of Acanthamoeba ployphaga mimivirus nucleoside diphosphate kinase complexed with TDP | | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, Probable nucleoside diphosphate kinase, ... | | 著者 | Jeudy, S, Claverie, J.M, Abergel, C. | | 登録日 | 2005-10-10 | | 公開日 | 2005-11-15 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Dissecting the unique nucleotide specificity of mimivirus nucleoside diphosphate kinase.
J.Virol., 83, 2009
|
|
1CLP
 | | CRYSTAL STRUCTURE OF A CALCIUM-INDEPENDENT PHOSPHOLIPASELIKE MYOTOXIC PROTEIN FROM BOTHROPS ASPER VENOM | | 分子名称: | MYOTOXIN II | | 著者 | Arni, R.K, Ward, R.J, Gutierrez, J.M, Tulinsky, A. | | 登録日 | 1994-09-12 | | 公開日 | 1994-11-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of a calcium-independent phospholipase-like myotoxic protein from Bothrops asper venom.
Acta Crystallogr.,Sect.D, 51, 1995
|
|
1K07
 | | Native FEZ-1 metallo-beta-lactamase from Legionella gormanii | | 分子名称: | ACETATE ION, FEZ-1 beta-lactamase, GLYCEROL, ... | | 著者 | Garcia-Saez, I, Mercuri, P.S, Kahn, R, Papamicael, C, Frere, J.M, Galleni, M, Dideberg, O. | | 登録日 | 2001-09-18 | | 公開日 | 2003-01-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Three-dimensional Structure of FEZ-1, a Monomeric Subclass B3 Metallo-[beta]-lactamase from Fluoribacter gormanii, in Native Form and in Complex with -Captopril
J.MOL.BIOL., 325, 2003
|
|
3VBE
 | |
2BBS
 | | Human deltaF508 NBD1 with three solubilizing mutations | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | | 著者 | Lewis, H.A, Kearins, M.C, Conners, K, Zhao, X, Lu, F, Sauder, J.M, Emtage, S. | | 登録日 | 2005-10-17 | | 公開日 | 2005-11-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure and dynamics of NBD1 from CFTR characterized using crystallography and hydrogen/deuterium exchange mass spectrometry.
J.Mol.Biol., 396, 2010
|
|
4LYF
 | | Crystal Structure of small molecule vinylsulfonamide 8 covalently bound to K-Ras G12C | | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, N-{1-[N-(4,5-dichloro-2-hydroxyphenyl)glycyl]piperidin-4-yl}ethanesulfonamide | | 著者 | Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M. | | 登録日 | 2013-07-31 | | 公開日 | 2013-11-27 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.568 Å) | | 主引用文献 | K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
|
|
1JVP
 | |
3VJF
 | | Crystal structure of de novo 4-helix bundle protein WA20 | | 分子名称: | POTASSIUM ION, WA20 | | 著者 | Arai, R, Kimura, A, Kobayashi, N, Matsuo, K, Sato, T, Wang, A.F, Platt, J.M, Bradley, L.H, Hecht, M.H. | | 登録日 | 2011-10-18 | | 公開日 | 2012-03-28 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Domain-swapped dimeric structure of a stable and functional de novo four-helix bundle protein, WA20
J.Phys.Chem.B, 116, 2012
|
|
1K2B
 | | Combining Mutations in HIV-1 Protease to Understand Mechanisms of Resistance | | 分子名称: | N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide, PROTEASE RETROPEPSIN | | 著者 | Mahalingam, B, Boross, P, Wang, Y.-F, Louis, J.M, Fischer, C, Tozser, J, W Harrison, R, Weber, I.T. | | 登録日 | 2001-09-26 | | 公開日 | 2002-07-10 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Combining mutations in HIV-1 protease to understand mechanisms of resistance.
Proteins, 48, 2002
|
|
4M1W
 | | Crystal Structure of small molecule vinylsulfonamide covalently bound to K-Ras G12C | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, K-Ras GTPase, MAGNESIUM ION, ... | | 著者 | Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M. | | 登録日 | 2013-08-04 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
|
|
2CFK
 | | AGAO in complex with wc5 (Ru-wire inhibitor, 5-carbon linker) | | 分子名称: | COPPER (II) ION, GLYCEROL, PHENYLETHYLAMINE OXIDASE, ... | | 著者 | Langley, D.B, Duff, A.P, Freeman, H.C, Guss, J.M, Juda, G.A, Dooley, D.M, Contakes, S.M, Halpern-Manners, N.W, Dunn, A.R, Gray, H.B. | | 登録日 | 2006-02-21 | | 公開日 | 2007-05-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Enantiomer-specific binding of ruthenium(II) molecular wires by the amine oxidase of Arthrobacter globiformis.
J. Am. Chem. Soc., 130, 2008
|
|
1JRQ
 | | X-ray Structure Analysis of the Role of the Conserved Tyrosine-369 in Active Site of E. coli Amine Oxidase | | 分子名称: | CALCIUM ION, COPPER (II) ION, Copper amine oxidase | | 著者 | Murray, J.M, Kurtis, C.R, Tambarajah, W, Saysell, C.G, Wilmot, C.M, Parsons, M.R, Phillips, S.E.V, Knowles, P.F, McPherson, M.J. | | 登録日 | 2001-08-14 | | 公開日 | 2001-11-21 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Conserved tyrosine-369 in the active site of Escherichia coli copper amine oxidase is not essential.
Biochemistry, 40, 2001
|
|
1K4F
 | | CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 AT 1.6 A RESOLUTION | | 分子名称: | Beta-lactamase PSE-2, SULFATE ION | | 著者 | Kerff, F, Fonze, E, Bouillene, F, Frere, J.M, Charlier, P. | | 登録日 | 2001-10-08 | | 公開日 | 2001-10-31 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of the class D beta-lactamase OXA-2
To be Published
|
|
1K64
 | | NMR Structue of alpha-conotoxin EI | | 分子名称: | alpha-conotoxin EI | | 著者 | Park, K.H, Suk, J.E, Jacobsen, R, Gray, W.R, McIntosh, J.M, Han, K.H. | | 登録日 | 2001-10-15 | | 公開日 | 2003-09-09 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution conformation of alpha-conotoxin EI, a neuromuscular toxin specific for the alpha 1/delta subunit interface of torpedo nicotinic acetylcholine receptor
J.BIOL.CHEM., 276, 2001
|
|
1FSL
 | | FERRIC SOYBEAN LEGHEMOGLOBIN COMPLEXED WITH NICOTINATE | | 分子名称: | LEGHEMOGLOBIN A, NICOTINIC ACID, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Ellis, P.J, Guss, J.M, Freeman, H.C. | | 登録日 | 1995-12-12 | | 公開日 | 1996-06-26 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of ferric soybean leghemoglobin a nicotinate at 2.3 A resolution.
Acta Crystallogr.,Sect.D, 53, 1997
|
|
1KAC
 | | KNOB DOMAIN FROM ADENOVIRUS SEROTYPE 12 IN COMPLEX WITH DOMAIN 1 OF ITS CELLULAR RECEPTOR CAR | | 分子名称: | PROTEIN (COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR), PROTEIN (FIBER KNOB PROTEIN) | | 著者 | Bewley, M.C, Springer, K, Zhang, Y.B, Freimuth, P, Flanagan, J.M. | | 登録日 | 1999-05-05 | | 公開日 | 1999-11-24 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural analysis of the mechanism of adenovirus binding to its human cellular receptor, CAR.
Science, 286, 1999
|
|
1TZQ
 | | Crystal structure of the equinatoxin II 8-69 double cysteine mutant | | 分子名称: | Equinatoxin II | | 著者 | Kristan, K, Podlesek, Z, Hojnik, V, Gutirrez-Aguirre, I, Guncar, G, Turk, D.A, Gonzalez-Maas, J.M, Lakey, J.H, Anderluh, G. | | 登録日 | 2004-07-11 | | 公開日 | 2004-09-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Pore formation by equinatoxin, a eukaryotic pore-forming toxin, requires a flexible N-terminal region and a stable beta-sandwich
J.Biol.Chem., 279, 2004
|
|
1K6S
 | | STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 IN COMPLEX WITH A PHENYLBORONIC ACID | | 分子名称: | 4-IODO-ACETAMIDO PHENYLBORONIC ACID, Beta-lactamase PSE-2, CALCIUM ION, ... | | 著者 | Kerff, F, Fonze, E, Sauvage, E, Frere, J.M, Charlier, P. | | 登録日 | 2001-10-17 | | 公開日 | 2003-06-24 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | CRYSTAL STRUCTURE OF CLASS D BETA-LACTAMASE OXA-10 IN COMPLEX WITH DIFFERENT SUBSTRATES AND ONE INHIBITOR.
To be Published
|
|
1K6R
 | | STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 IN COMPLEX WITH MOXALACTAM | | 分子名称: | (2R)-2-((R)-CARBOXY{[CARBOXY(4-HYDROXYPHENYL)ACETYL]AMINO}METHOXYMETHYL)-5-METHYLENE-5,6-DIHYDRO-2H-1,3-OXAZINE-4-CARBO XYLIC ACID, Beta-lactamase PSE-2 | | 著者 | Kerff, F, Fonze, E, Sauvage, E, Frere, J.M, Charlier, P. | | 登録日 | 2001-10-17 | | 公開日 | 2003-06-24 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | CRYSTAL STRUCTURE OF CLASS D BETA-LACTAMASE OXA-10 IN COMPLEX WITH DIFFERENT SUBSTRATES AND ONE INHIBITOR.
To be Published
|
|
