3E7W
 
 | | Crystal structure of DLTA: Implications for the reaction mechanism of non-ribosomal peptide synthetase (NRPS) adenylation domains | | 分子名称: | ADENOSINE MONOPHOSPHATE, D-alanine--poly(phosphoribitol) ligase subunit 1, PHOSPHATE ION | | 著者 | Yonus, H, Neumann, P, Zimmermann, S, May, J.J, Marahiel, M.A, Stubbs, M.T. | | 登録日 | 2008-08-19 | | 公開日 | 2008-09-09 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Crystal structure of DltA. Implications for the reaction mechanism of non-ribosomal peptide synthetase adenylation domains
J.Biol.Chem., 283, 2008
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7M0I
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1O0B
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7MTB
 | | Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab6 | | 分子名称: | Fab6 heavy chain, Fab6 light chain, RETINAL, ... | | 著者 | Chen, Q, Chen, C.-L, Tesmer, J.J.G. | | 登録日 | 2021-05-13 | | 公開日 | 2021-07-07 | | 最終更新日 | 2021-08-25 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
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7MT8
 | | Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin | | 分子名称: | RETINAL, Rhodopsin, Rhodopsin kinase GRK1, ... | | 著者 | Chen, Q, Chen, C.-L, Tesmer, J.J.G. | | 登録日 | 2021-05-13 | | 公開日 | 2021-07-07 | | 最終更新日 | 2021-08-25 | | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | | 主引用文献 | Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
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7MTA
 | | Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab1 | | 分子名称: | Fab1 Heavy chain, Fab1 Light chain, RETINAL, ... | | 著者 | Chen, Q, Chen, C.-L, Tesmer, J.J.G. | | 登録日 | 2021-05-13 | | 公開日 | 2021-07-07 | | 最終更新日 | 2021-08-25 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
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7MT9
 | | Rhodopsin kinase (GRK1) in complex with rhodopsin | | 分子名称: | RETINAL, Rhodopsin, Rhodopsin kinase GRK1, ... | | 著者 | Chen, Q, Chen, C.-L, Tesmer, J.J.G. | | 登録日 | 2021-05-13 | | 公開日 | 2021-07-07 | | 最終更新日 | 2021-08-25 | | 実験手法 | ELECTRON MICROSCOPY (7 Å) | | 主引用文献 | Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
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7JVE
 | | Crystal structure of Salmonella enterica Typhimurium BcfH | | 分子名称: | 1,2-ETHANEDIOL, DsbA family protein, MAGNESIUM ION, ... | | 著者 | Subedi, P, Heras, B, Hor, L, Paxman, J.J. | | 登録日 | 2020-08-21 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Salmonella enterica BcfH Is a Trimeric Thioredoxin-Like Bifunctional Enzyme with Both Thiol Oxidase and Disulfide Isomerase Activities.
Antioxid.Redox Signal., 35, 2021
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3E2S
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7ARE
 | | DNA origami pointer object v2 | | 分子名称: | SCAFFOLD STRAND, STAPLE STRAND | | 著者 | Thomas, M, Feigl, E, Kohler, F, Kube, M, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H. | | 登録日 | 2020-10-24 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | | 主引用文献 | Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
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3C9C
 | | Structural Basis of Histone H4 Recognition by p55 | | 分子名称: | CADMIUM ION, Chromatin assembly factor 1 p55 subunit, Histone H4, ... | | 著者 | Song, J.J, Garlick, J.D, Kingston, R.E. | | 登録日 | 2008-02-15 | | 公開日 | 2008-05-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis of histone H4 recognition by p55.
Genes Dev., 22, 2008
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4Z8B
 | | crystal structure of a DGL mutant - H51G H131N | | 分子名称: | 5-bromo-4-chloro-1H-indol-3-yl alpha-D-mannopyranoside, CALCIUM ION, GLYCEROL, ... | | 著者 | Zamora-Caballero, S, Perez, A, Sanz, L, Bravo, J, Calvete, J.J. | | 登録日 | 2015-04-08 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.951 Å) | | 主引用文献 | Quaternary structure of Dioclea grandiflora lectin assessed by equilibrium sedimentation and crystallographic analysis of recombinant mutants.
Febs Lett., 589, 2015
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1F12
 | | L-3-HYDROXYACYL-COA DEHYDROGENASE COMPLEXED WITH 3-HYDROXYBUTYRYL-COA | | 分子名称: | 3-HYDROXYBUTANOYL-COENZYME A, L-3-HYDROXYACYL-COA DEHYDROGENASE | | 著者 | Barycki, J.J, O'Brien, L.K, Strauss, A.W, Banaszak, L.J. | | 登録日 | 2000-05-18 | | 公開日 | 2000-09-27 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Sequestration of the active site by interdomain shifting. Crystallographic and spectroscopic evidence for distinct conformations of L-3-hydroxyacyl-CoA dehydrogenase.
J.Biol.Chem., 275, 2000
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7ART
 | | 48 helix bundle DNA origami brick | | 分子名称: | SCAFFOLD STRAND, STAPLE STRAND | | 著者 | Feigl, E, Kube, M, Kohler, F, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H. | | 登録日 | 2020-10-26 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (10 Å) | | 主引用文献 | Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
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7VDT
 | | The motor-nucleosome module of human chromatin remodeling PBAF-nucleosome complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (207-MER), ... | | 著者 | Chen, Z.C, Chen, K.J, Yuan, J.J. | | 登録日 | 2021-09-07 | | 公開日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structure of human chromatin-remodelling PBAF complex bound to a nucleosome.
Nature, 605, 2022
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7AS5
 | | 126 helix bundle DNA nanostructure | | 分子名称: | SCAFFOLD STRAND, STAPLE STRAND | | 著者 | Kube, M, Kohler, F, Feigl, E, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H. | | 登録日 | 2020-10-27 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (9.8 Å) | | 主引用文献 | Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
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7VDV
 | | The overall structure of human chromatin remodeling PBAF-nucleosome complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, AT-rich interactive domain-containing protein 2,AT-rich interactive domain-containing protein 2, Actin, ... | | 著者 | Chen, Z.C, Chen, K.J, Yuan, J.J. | | 登録日 | 2021-09-07 | | 公開日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of human chromatin-remodelling PBAF complex bound to a nucleosome.
Nature, 605, 2022
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2XP2
 | | Structure of the Human Anaplastic Lymphoma Kinase in Complex with Crizotinib (PF-02341066) | | 分子名称: | 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine, TYROSINE-PROTEIN KINASE RECEPTOR | | 著者 | McTigue, M, Deng, Y, Liu, W, Brooun, A, Timofeevski, S, Marrone, T, Cui, J.J. | | 登録日 | 2010-08-24 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure Based Drug Design of Crizotinib (Pf-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal-Epithelial Transition Factor (C-met) Kinase and Anaplastic Lymphoma Kinase (Alk).
J.Med.Chem, 54, 2011
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2XM8
 | | Co-crystal structure of a small molecule inhibitor bound to the kinase domain of Chk2 | | 分子名称: | 2-{4-[(3S)-PYRROLIDIN-3-YLAMINO]QUINAZOLIN-2-YL}PHENOL, SERINE/THREONINE-PROTEIN KINASE CHK2 | | 著者 | Caldwell, J.J, Welsh, E.J, Matijssen, C, Anderson, V.E, Antoni, L, Boxall, K, Urban, F, Hayes, A, Raynaud, F.I, Rigoreau, L.J, Raynham, T, Aherne, G.W, Pearl, L.H, Oliver, A.W, Garrett, M.D, Collins, I. | | 登録日 | 2010-07-26 | | 公開日 | 2011-01-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structure-Based Design of Potent and Selective 2-(Quinazolin-2-Yl)Phenol Inhibitors of Checkpoint Kinase 2.
J.Med.Chem., 54, 2011
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2WTC
 | | CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR | | 分子名称: | 4-[2-AMINO-5-(4-HYDROXY-3-METHOXYPHENYL)PYRIDIN-3-YL]BENZAMIDE, NITRATE ION, SERINE/THREONINE-PROTEIN KINASE CHK2 | | 著者 | Hilton, S, Naud, S, Caldwell, J.J, Boxall, K, Burns, S, Anderson, V.E, Antoni, L, Allen, C.E, Pearl, L.H, Oliver, A.W, Aherne, G.W, Garrett, M.D, Collins, I. | | 登録日 | 2009-09-15 | | 公開日 | 2009-12-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Identification and Characterisation of 2-Aminopyridine Inhibitors of Checkpoint Kinase 2
Bioorg.Med.Chem., 18, 2010
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7ARV
 | | TwistTower_native-twist | | 分子名称: | SCAFFOLD STRAND, STAPLE STRAND | | 著者 | Kube, M, Kohler, F, Feigl, E, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H. | | 登録日 | 2020-10-26 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | | 主引用文献 | Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
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4ZCU
 | | Structure of calcium-bound regulatory domain of the human ATP-Mg/Pi carrier in the P2 form | | 分子名称: | CALCIUM ION, Calcium-binding mitochondrial carrier protein SCaMC-1, GLYCEROL, ... | | 著者 | Harborne, S.P.D, Ruprecht, J.J, Kunji, E.R.S. | | 登録日 | 2015-04-16 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Calcium-induced conformational changes in the regulatory domain of the human mitochondrial ATP-Mg/Pi carrier.
Biochim.Biophys.Acta, 1847, 2015
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7AS7
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7L0R
 | | Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, without AHD | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G. | | 登録日 | 2020-12-12 | | 公開日 | 2021-01-06 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
Nat.Struct.Mol.Biol., 28, 2021
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7ARY
 | | Twist-Tower_twist-corrected-variant | | 分子名称: | SCAFFOLD STRAND, STAPLE STRAND | | 著者 | Kube, M, Kohler, F, Feigl, E, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H. | | 登録日 | 2020-10-26 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (8.5 Å) | | 主引用文献 | Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
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