2RMG
 
 | | Human Urocortin 2 | | 分子名称: | Urocortin-2 | | 著者 | Grace, C.R.R, Perrin, M.H, Cantle, J.P, Vale, W.W, Rivier, J.E, Riek, R. | | 登録日 | 2007-10-16 | | 公開日 | 2008-01-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Common and divergent structural features of a series of corticotropin releasing factor-related peptides
J.Am.Chem.Soc., 129, 2007
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7AT1
 | | CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ASPARTATE CARBAMOYLTRANSFERASE (R STATE), CATALYTIC CHAIN, ... | | 著者 | Gouaux, J.E, Stevens, R.C, Lipscomb, W.N. | | 登録日 | 1989-09-22 | | 公開日 | 1990-10-15 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structures of aspartate carbamoyltransferase ligated with phosphonoacetamide, malonate, and CTP or ATP at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
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7AJI
 | | bovine ATP synthase dimer state3:state2 | | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ATP synthase F(0) complex subunit B1, mitochondrial, ... | | 著者 | Spikes, T.E, Montgomery, M.G, Walker, J.E. | | 登録日 | 2020-09-29 | | 公開日 | 2021-02-03 | | 最終更新日 | 2021-02-24 | | 実験手法 | ELECTRON MICROSCOPY (11.4 Å) | | 主引用文献 | Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7AJE
 | | bovine ATP synthase dimer state2:state1 | | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ATP synthase F(0) complex subunit B1, mitochondrial, ... | | 著者 | Spikes, T.E, Montgomery, M.G, Walker, J.E. | | 登録日 | 2020-09-29 | | 公開日 | 2021-02-03 | | 最終更新日 | 2021-02-24 | | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | | 主引用文献 | Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7AHL
 | | ALPHA-HEMOLYSIN FROM STAPHYLOCOCCUS AUREUS | | 分子名称: | ALPHA-HEMOLYSIN | | 著者 | Song, L, Hobaugh, M, Shustak, C, Cheley, S, Bayley, H, Gouaux, J.E. | | 登録日 | 1996-12-02 | | 公開日 | 1998-01-14 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore.
Science, 274, 1996
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7AJG
 | | bovine ATP synthase dimer state2:state3 | | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ATP synthase F(0) complex subunit B1, mitochondrial, ... | | 著者 | Spikes, T.E, Montgomery, M.G, Walker, J.E. | | 登録日 | 2020-09-29 | | 公開日 | 2021-02-03 | | 最終更新日 | 2021-02-24 | | 実験手法 | ELECTRON MICROSCOPY (10.7 Å) | | 主引用文献 | Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes.
Proc.Natl.Acad.Sci.USA, 118, 2021
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2RM9
 | | Astressin2B | | 分子名称: | Astressin2B | | 著者 | Grace, C.R.R, Perrin, M.H, Cantle, J.P, Vale, W.W, Rivier, J.E, Riek, R. | | 登録日 | 2007-10-16 | | 公開日 | 2008-01-01 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Common and divergent structural features of a series of corticotropin releasing factor-related peptides
J.Am.Chem.Soc., 129, 2007
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2RME
 | | Stressin | | 分子名称: | Stressin | | 著者 | Grace, C.R.R, Perrin, M.H, Cantle, J.P, Vale, W.W, Rivier, J.E, Riek, R. | | 登録日 | 2007-10-16 | | 公開日 | 2008-01-01 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Common and divergent structural features of a series of corticotropin releasing factor-related peptides
J.Am.Chem.Soc., 129, 2007
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2RMD
 | | Astressin-B | | 分子名称: | ASTRESSIN-B | | 著者 | Grace, C.R.R, Perrin, M.H, Cantle, J.P, Vale, W.W, Rivier, J.E, Riek, R. | | 登録日 | 2007-10-16 | | 公開日 | 2008-01-01 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Common and divergent structural features of a series of corticotropin releasing factor-related peptides
J.Am.Chem.Soc., 129, 2007
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7AJF
 | | bovine ATP synthase dimer state2:state2 | | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ATP synthase F(0) complex subunit B1, mitochondrial, ... | | 著者 | Spikes, T.E, Montgomery, M.G, Walker, J.E. | | 登録日 | 2020-09-29 | | 公開日 | 2021-02-03 | | 最終更新日 | 2021-02-24 | | 実験手法 | ELECTRON MICROSCOPY (8.45 Å) | | 主引用文献 | Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes.
Proc.Natl.Acad.Sci.USA, 118, 2021
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2RMH
 | | Human Urocortin 3 | | 分子名称: | Urocortin-3 | | 著者 | Grace, C.R.R, Perrin, M.H, Cantle, J.P, Vale, W.W, Rivier, J.E, Riek, R. | | 登録日 | 2007-10-16 | | 公開日 | 2008-01-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Common and divergent structural features of a series of corticotropin releasing factor-related peptides
J.Am.Chem.Soc., 129, 2007
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5IN9
 | | Crystal structure of Grp94 bound to methyl 3-chloro-2-(2-(1-((5-chlorofuran-2-yl)methyl)-1H-imidazol-2-yl)ethyl)-4,6-dihydroxybenzoate, an inhibitor based on the BnIm and Radamide scaffolds. | | 分子名称: | Endoplasmin, GLYCEROL, TRIETHYLENE GLYCOL, ... | | 著者 | Lieberman, R.L, Huard, D.J.E, Kizziah, J.L. | | 登録日 | 2016-03-07 | | 公開日 | 2016-05-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Development of Glucose Regulated Protein 94-Selective Inhibitors Based on the BnIm and Radamide Scaffold.
J.Med.Chem., 59, 2016
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2UZR
 | | A transforming mutation in the pleckstrin homology domain of AKT1 in cancer (AKT1-PH_E17K) | | 分子名称: | RAC-alpha serine/threonine-protein kinase | | 著者 | Carpten, J.D, Faber, A.L, Horn, C, Donoho, G.P, Briggs, S.L, Robbins, C.M, Hostetter, G, Boguslawski, S, Moses, T.Y, Savage, S, Uhlik, M, Lin, A, Du, J, Qian, Y.W, Zeckner, D.J, Tucker-Kellogg, G, Touchman, J, Patel, K, Mousses, S, Bittner, M, Schevitz, R, Lai, M.H, Blanchard, K.L, Thomas, J.E. | | 登録日 | 2007-05-01 | | 公開日 | 2007-07-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
Nature, 448, 2007
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7ANM
 | | Nudaurelia capensis omega virus capsid: virus-like particles expressed in Nicotiana benthamiana | | 分子名称: | p70 | | 著者 | Castells-Graells, R, Ribeiro, J.R.S, Domitrovic, T, Hesketh, E.L, Scarff, C.A, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P. | | 登録日 | 2020-10-12 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | | 主引用文献 | Plant-expressed virus-like particles reveal the intricate maturation process of a eukaryotic virus.
Commun Biol, 4, 2021
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7ATA
 | | Nudaurelia capensis omega virus procapsid: virus-like particles expressed in Nicotiana benthamiana | | 分子名称: | p70 | | 著者 | Castells-Graells, R, Ribeiro, J.R.S, Domitrovic, T, Hesketh, E.L, Scarff, C.A, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P. | | 登録日 | 2020-10-29 | | 公開日 | 2021-08-25 | | 実験手法 | ELECTRON MICROSCOPY (6.63 Å) | | 主引用文献 | Plant-expressed virus-like particles reveal the intricate maturation process of a eukaryotic virus.
Commun Biol, 4, 2021
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1GNR
 | | X-RAY CRYSTAL STRUCTURE ANALYSIS OF THE CATALYTIC DOMAIN OF THE ONCOGENE PRODUCT P21H-RAS COMPLEXED WITH CAGED GTP AND MANT DGPPNHP | | 分子名称: | C-H-RAS P21 PROTEIN, GUANOSINE 5'-TRIPHOSPHATE P3-[1-(2-NITROPHENYL)ETHYL ESTER], MAGNESIUM ION | | 著者 | Scheidig, A, Franken, S.M, Corrie, J.E.T, Reid, G.P, Wittinghofer, A, Pai, E.F, Goody, R.S. | | 登録日 | 1995-05-11 | | 公開日 | 1995-07-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | X-ray crystal structure analysis of the catalytic domain of the oncogene product p21H-ras complexed with caged GTP and mant dGppNHp.
J.Mol.Biol., 253, 1995
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2VRG
 | | Structure of human MCFD2 | | 分子名称: | CALCIUM ION, MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 | | 著者 | Guy, J.E, Wigren, E, Svard, M, Hard, T, Lindqvist, Y. | | 登録日 | 2008-04-04 | | 公開日 | 2008-07-15 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | New insights into multiple coagulation factor deficiency from the solution structure of human MCFD2.
J. Mol. Biol., 381, 2008
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2W1F
 | | Structure determination of Aurora Kinase in complex with inhibitor | | 分子名称: | N-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDE, SERINE/THREONINE-PROTEIN KINASE 6 | | 著者 | Howard, S, Berdini, V, Boulstridge, J.A, Carr, M.G, Cross, D.M, Curry, J, Devine, L.A, Early, T.R, Fazal, L, Gill, A.L, Heathcote, M, Maman, S, Matthews, J.E, McMenamin, R.L, Navarro, E.F, O'Brien, M.A, O'Reilly, M, Rees, D.C, Reule, M, Tisi, D, Williams, G, Vinkovic, M, Wyatt, P.G. | | 登録日 | 2008-10-17 | | 公開日 | 2009-01-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Fragment-Based Discovery of the Pyrazol-4-Yl Urea (at9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity.
J.Med.Chem., 52, 2009
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2W1G
 | | Structure determination of Aurora Kinase in complex with inhibitor | | 分子名称: | 2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-6-(MORPHOLIN-4-IUM-4-YLMETHYL)-1H-3,1-BENZIMIDAZOL-3-IUM, SERINE/THREONINE-PROTEIN KINASE 6 | | 著者 | Howard, S, Berdini, V, Boulstridge, J.A, Carr, M.G, Cross, D.M, Curry, J, Devine, L.A, Early, T.R, Fazal, L, Gill, A.L, Heathcote, M, Maman, S, Matthews, J.E, McMenamin, R.L, Navarro, E.F, O'Brien, M.A, O'Reilly, M, Rees, D.C, Reule, M, Tisi, D, Williams, G, Vinkovic, M, Wyatt, P.G. | | 登録日 | 2008-10-17 | | 公開日 | 2009-01-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Fragment-Based Discovery of the Pyrazol-4-Yl Urea (at9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity.
J.Med.Chem., 52, 2009
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2W1C
 | | Structure determination of Aurora Kinase in complex with inhibitor | | 分子名称: | 4-{[2-(4-{[(4-FLUOROPHENYL)CARBONYL]AMINO}-1H-PYRAZOL-3-YL)-1H-BENZIMIDAZOL-6-YL]METHYL}MORPHOLIN-4-IUM, SERINE/THREONINE-PROTEIN KINASE 6 | | 著者 | Howard, S, Berdini, V, Boulstridge, J.A, Carr, M.G, Cross, D.M, Curry, J, Devine, L.A, Early, T.R, Fazal, L, Gill, A.L, Heathcote, M, Maman, S, Matthews, J.E, McMenamin, R.L, Navarro, E.F, O'Brien, M.A, O'Reilly, M, Rees, D.C, Reule, M, Tisi, D, Williams, G, Vinkovic, M, Wyatt, P.G. | | 登録日 | 2008-10-17 | | 公開日 | 2009-01-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | | 主引用文献 | Fragment-Based Discovery of the Pyrazol-4-Yl Urea (at9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity.
J.Med.Chem., 52, 2009
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8FRR
 | | Wild-type myocilin olfactomedin domain | | 分子名称: | CALCIUM ION, GLYCEROL, Myocilin, ... | | 著者 | Ma, M.T, Lieberman, R.L, Huard, D.J.E. | | 登録日 | 2023-01-08 | | 公開日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | | 主引用文献 | Competition between inside-out unfolding and pathogenic aggregation in an amyloid-forming beta-propeller.
Nat Commun, 15, 2024
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2VIN
 | | Fragment-Based Discovery of Mexiletine Derivatives as Orally Bioavailable Inhibitors of Urokinase-Type Plasminogen Activator | | 分子名称: | (2R)-1-(2,6-dimethylphenoxy)propan-2-amine, ACETATE ION, SULFATE ION, ... | | 著者 | Frederickson, M, Callaghan, O, Chessari, G, Congreve, M, Cowan, S.R, Matthews, J.E, McMenamin, R, Smith, D, Vinkovic, M, Wallis, N.G. | | 登録日 | 2007-12-05 | | 公開日 | 2008-01-22 | | 最終更新日 | 2017-07-05 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Fragment-Based Discovery of Mexiletine Derivatives as Orally Bioavailable Inhibitors of Urokinase-Type Plasminogen Activator
J.Med.Chem., 51, 2008
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2VIX
 | | Methylated Shigella flexneri MxiC | | 分子名称: | ACETATE ION, GLYCEROL, PROTEIN MXIC | | 著者 | Deane, J.E, Roversi, P, King, C, Johnson, S, Lea, S.M. | | 登録日 | 2007-12-05 | | 公開日 | 2008-03-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structures of the Shigella Flexneri Type 3 Secretion System Protein Mxic Reveal Conformational Variability Amongst Homologues.
J.Mol.Biol., 377, 2008
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2W46
 | | CBM35 from Cellvibrio japonicus Abf62 | | 分子名称: | CALCIUM ION, ESTERASE D, SODIUM ION | | 著者 | Montainer, C, Lammerts van Bueren, A, Dumon, C, Flint, J.E, Correia, M.A, Prates, J.A, Firbank, S.J, Lewis, R.J, Grondin, G.G, Ghinet, M.G, Gloster, T.M, Herve, C, Knox, J.P, Talbot, B.G, Turkenburg, J.P, Kerovuo, J, Brzezinski, R, Fontes, C.M.G.A, Davies, G.J, Boraston, A.B, Gilbert, H.J. | | 登録日 | 2008-11-21 | | 公開日 | 2009-01-27 | | 最終更新日 | 2017-06-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Evidence that Family 35 Carbohydrate Binding Modules Display Conserved Specificity But Divergent Function.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2WAA
 | | Structure of a family two carbohydrate esterase from Cellvibrio japonicus | | 分子名称: | ACETATE ION, GLYCEROL, XYLAN ESTERASE, ... | | 著者 | Montainer, C, Money, V.A, Pires, V.M.R, Flint, J.E, Pinheiro, B.A, Goyal, A, Prates, J.A.M, Izumi, A, Stalbrand, H, Kolenova, K, Topakas, E, Dodson, E.J, Bolam, D.N, Davies, G.J, Fontes, C.M.G.A, Gilbert, H.J. | | 登録日 | 2009-02-04 | | 公開日 | 2009-03-24 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions.
Plos Biol., 7, 2009
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