4CJN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4cjn by Molmil](/molmil-images/mine/4cjn) | Crystal structure of PBP2a from MRSA in complex with quinazolinone ligand | Descriptor: | (E)-3-(2-(4-cyanostyryl)-4-oxoquinazolin-3(4H)-yl)benzoic acid, CADMIUM ION, CHLORIDE ION, ... | Authors: | Bouley, R, Otero, L.H, Rojas-Altuve, A, Hermoso, J.A. | Deposit date: | 2013-12-21 | Release date: | 2015-02-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.947 Å) | Cite: | Discovery of Antibiotic (E)-3-(3-Carboxyphenyl)-2-(4-Cyanostyryl)Quinazolin-4(3H)-One. J.Am.Chem.Soc., 137, 2015
|
|
6GNT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gnt by Molmil](/molmil-images/mine/6gnt) | Crystal Structure of Leishmania major N-Myristoyltransferase (NMT) With Bound Myristoyl-CoA and a Quionlinyl aryl sulphonamide ligand | Descriptor: | 4-[4-(1-methylpiperidin-4-yl)butyl]-~{N}-(6-pyrrolidin-1-ylquinolin-5-yl)benzenesulfonamide, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase, ... | Authors: | Robinson, D.A, Harrison, J.R, Brand, S, Smith, V.C, Thompson, S, Smith, A, Davies, K, Mok, N.Y, Torrie, L.S, Collie, I, Hallyburton, I, Norval, S, Simeons, F.R.C, Stojanovski, L, Frearson, J.A, Brenk, R, Wyatt, P.G, Gilbert, I.H, Read, K.D. | Deposit date: | 2018-05-31 | Release date: | 2018-09-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors. J. Med. Chem., 61, 2018
|
|
3PFR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pfr by Molmil](/molmil-images/mine/3pfr) | Crystal structure of D-Glucarate dehydratase related protein from Actinobacillus Succinogenes complexed with D-Glucarate | Descriptor: | D-GLUCARATE, MAGNESIUM ION, Mandelate racemase/muconate lactonizing protein | Authors: | Fedorov, A.A, Fedorov, E.V, Mills-Groninger, F, Ghasempur, S, Gerlt, J.A, Almo, S.C. | Deposit date: | 2010-10-29 | Release date: | 2011-11-02 | Method: | X-RAY DIFFRACTION (1.899 Å) | Cite: | Crystal structure of D-Glucarate dehydratase related protein from Actinobacillus Succinogenes complexed with D-Glucarate To be Published
|
|
6DB8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6db8 by Molmil](/molmil-images/mine/6db8) | Structural basis for promiscuous binding and activation of fluorogenic dyes by DIR2s RNA aptamer | Descriptor: | 2-[(Z)-(3-methyl-1,3-benzoxazol-2(3H)-ylidene)methyl]-3-(3-sulfopropyl)-1,3-benzothiazol-3-ium, Fab-Heavy chain, Fab-Light chain, ... | Authors: | Shao, Y, Shelke, S.A, Laski, A, Piccirilli, J.A. | Deposit date: | 2018-05-02 | Release date: | 2018-11-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.86541343 Å) | Cite: | Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif. Nat Commun, 9, 2018
|
|
6D9G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6d9g by Molmil](/molmil-images/mine/6d9g) | |
6DB9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6db9 by Molmil](/molmil-images/mine/6db9) | Structural basis for promiscuous binding and activation of fluorogenic dyes by DIR2s RNA aptamer | Descriptor: | Fab-Heavy-Chain, Fab-Light-Chain, MAGNESIUM ION, ... | Authors: | Shao, Y, Shelke, S.A, Laski, A, Piccirilli, J.A. | Deposit date: | 2018-05-02 | Release date: | 2018-11-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.025 Å) | Cite: | Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif. Nat Commun, 9, 2018
|
|
3Q4D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3q4d by Molmil](/molmil-images/mine/3q4d) | Crystal structure of dipeptide epimerase from Cytophaga hutchinsonii complexed with Mg and dipeptide D-Ala-L-Ala | Descriptor: | ALANINE, D-ALANINE, MAGNESIUM ION, ... | Authors: | Lukk, T, Gerlt, J.A, Nair, S.K. | Deposit date: | 2010-12-23 | Release date: | 2011-02-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
2XME
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xme by Molmil](/molmil-images/mine/2xme) | The X-ray structure of CTP:inositol-1-phosphate cytidylyltransferase from Archaeoglobus fulgidus | Descriptor: | CTP-INOSITOL-1-PHOSPHATE CYTIDYLYLTRANSFERASE, GLYCEROL | Authors: | Brito, J.A, Borges, N, Vonrhein, C, Santos, H, Archer, M. | Deposit date: | 2010-07-27 | Release date: | 2011-05-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Crystal Structure of Archaeoglobus Fulgidus Ctp:Inositol-1-Phosphate Cytidylyltransferase, a Key Enzyme for Di-Myo-Inositol-Phosphate Synthesis in (Hyper)Thermophiles. J.Bacteriol., 193, 2011
|
|
3PND
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pnd by Molmil](/molmil-images/mine/3pnd) | FAD binding by ApbE protein from Salmonella enterica: a new class of FAD binding proteins | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, Thiamine biosynthesis lipoprotein ApbE | Authors: | Boyd, J.M, Endrizzi, J.A, Hamilton, T.L, Christopherson, M.R, Mulder, D.W, Downs, D.M, Peters, J.W. | Deposit date: | 2010-11-18 | Release date: | 2011-01-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | FAD binding by ApbE protein from Salmonella enterica: a new class of FAD-binding proteins. J.Bacteriol., 193, 2011
|
|
1QLW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qlw by Molmil](/molmil-images/mine/1qlw) | |
2XMH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xmh by Molmil](/molmil-images/mine/2xmh) | The X-ray structure of CTP:inositol-1-phosphate cytidylyltransferase from Archaeoglobus fulgidus | Descriptor: | CITRATE ANION, CTP-INOSITOL-1-PHOSPHATE CYTIDYLYLTRANSFERASE | Authors: | Brito, J.A, Borges, N, Vonrhein, C, Santos, H, Archer, M. | Deposit date: | 2010-07-27 | Release date: | 2011-05-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of Archaeoglobus fulgidus CTP:inositol-1-phosphate cytidylyltransferase, a key enzyme for di-myo-inositol-phosphate synthesis in (hyper)thermophiles. J. Bacteriol., 193, 2011
|
|
3PQZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pqz by Molmil](/molmil-images/mine/3pqz) | Grb7 SH2 with peptide | Descriptor: | Growth factor receptor-bound protein 7, cyclic peptide | Authors: | Wilce, J.A. | Deposit date: | 2010-11-29 | Release date: | 2011-07-20 | Last modified: | 2011-09-21 | Method: | X-RAY DIFFRACTION (2.413 Å) | Cite: | Structural basis of binding by cyclic nonphosphorylated Peptide antagonists of grb7 implicated in breast cancer progression J.Mol.Biol., 412, 2011
|
|
3PSX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3psx by Molmil](/molmil-images/mine/3psx) | Crystal structure of the KT2 mutant of cytochrome P450 BM3 | Descriptor: | Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Yang, W, Whitehouse, C.J.C, Yorke, J.A, Bell, S.G, Zhou, W, Bartlam, M, Wong, L.L, Rao, Z. | Deposit date: | 2010-12-02 | Release date: | 2011-12-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure, electronic properties and catalytic behaviour of an activity-enhancing CYP102A1 (P450(BM3)) variant Dalton Trans, 40, 2011
|
|
3PT8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pt8 by Molmil](/molmil-images/mine/3pt8) | Structure of HbII-III-CN from Lucina pectinata at pH 5.0 | Descriptor: | CYANIDE ION, FORMIC ACID, GLYCEROL, ... | Authors: | Gavira, J.A, Ruiz-Martinez, C.R, Nieves-Marrero, C.A, Estremera-Andujar, R.A, Lopez-Garriga, J, Garcia-Ruiz, J.M. | Deposit date: | 2010-12-02 | Release date: | 2011-12-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.762 Å) | Cite: | New Crystallographic Structure of HbII-III-Oxy and CN forms from Lucina pectinata. To be Published
|
|
1ISB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1isb by Molmil](/molmil-images/mine/1isb) | STRUCTURE-FUNCTION IN E. COLI IRON SUPEROXIDE DISMUTASE: COMPARISONS WITH THE MANGANESE ENZYME FROM T. THERMOPHILUS | Descriptor: | FE (III) ION, IRON(III) SUPEROXIDE DISMUTASE | Authors: | Lah, M.S, Dixon, M, Pattridge, K.A, Stallings, W.C, Fee, J.A, Ludwig, M.L. | Deposit date: | 1994-07-12 | Release date: | 1994-09-30 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure-function in Escherichia coli iron superoxide dismutase: comparisons with the manganese enzyme from Thermus thermophilus. Biochemistry, 34, 1995
|
|
1Q80
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1q80 by Molmil](/molmil-images/mine/1q80) | Solution structure and dynamics of Nereis sarcoplasmic calcium binding protein | Descriptor: | Sarcoplasmic calcium-binding protein | Authors: | Rabah, G, Popescu, R, Cox, J.A, Engelborghs, Y, Craescu, C.T. | Deposit date: | 2003-08-20 | Release date: | 2004-09-21 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure and internal dynamics of NSCP, a compact calcium-binding protein. Febs J., 272, 2005
|
|
1OU4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ou4 by Molmil](/molmil-images/mine/1ou4) | Native PNP +Talo | Descriptor: | 6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase | Authors: | Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J. | Deposit date: | 2003-03-24 | Release date: | 2004-02-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system. Chem.Biol., 10, 2003
|
|
2AD5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ad5 by Molmil](/molmil-images/mine/2ad5) | Mechanisms of feedback regulation and drug resistance of CTP synthetases: structure of the E. coli CTPS/CTP complex at 2.8-Angstrom resolution. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, ... | Authors: | Endrizzi, J.A, Kim, H, Anderson, P.M, Baldwin, E.P. | Deposit date: | 2005-07-19 | Release date: | 2005-11-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mechanisms of Product Feedback Regulation and Drug Resistance in Cytidine Triphosphate Synthetases from the Structure of a CTP-Inhibited Complex(,). Biochemistry, 44, 2005
|
|
250D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 250d by Molmil](/molmil-images/mine/250d) | STRUCTURAL COMPARISON BETWEEN THE D(CTAG) SEQUENCE IN OLIGONUCLEOTIDES AND TRP AND MET REPRESSOR-OPERATOR COMPLEXES | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*CP*G)-3') | Authors: | Urpi, L, Tereshko, V, Malinina, L, Huynh-Dinh, T, Subirana, J.A. | Deposit date: | 1996-02-22 | Release date: | 1996-04-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Structural comparison between the d(CTAG) sequence in oligonucleotides and trp and met repressor-operator complexes. Nat.Struct.Biol., 3, 1996
|
|
3QJV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qjv by Molmil](/molmil-images/mine/3qjv) | The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus | Descriptor: | CARBON MONOXIDE, COPPER (I) ION, Cytochrome c oxidase polypeptide 2A, ... | Authors: | Liu, B, Zhang, Y, Sage, J.T, Doukov, T, Chen, Y, Stout, C.D, Fee, J.A. | Deposit date: | 2011-01-30 | Release date: | 2012-01-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural changes that occur upon photolysis of the Fe(II)(a3)-CO complex in the cytochrome ba(3)-oxidase of Thermus thermophilus: A combined X-ray crystallographic and infrared spectral study demonstrates CO binding to Cu(B). Biochim.Biophys.Acta, 1817, 2012
|
|
1OV6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ov6 by Molmil](/molmil-images/mine/1ov6) | M64V PNP + ALLO | Descriptor: | 9-(6-DEOXY-BETA-D-ALLOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase | Authors: | Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, P.W, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J. | Deposit date: | 2003-03-25 | Release date: | 2004-02-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system. Chem.Biol., 10, 2003
|
|
3QJR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qjr by Molmil](/molmil-images/mine/3qjr) | The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus | Descriptor: | CARBON MONOXIDE, COPPER (I) ION, Cytochrome c oxidase polypeptide 2A, ... | Authors: | Liu, B, Zhang, Y, Sage, J.T, Doukov, T, Chen, Y, Stout, C.D, Fee, J.A. | Deposit date: | 2011-01-30 | Release date: | 2012-01-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural changes that occur upon photolysis of the Fe(II)(a3)-CO complex in the cytochrome ba(3)-oxidase of Thermus thermophilus: A combined X-ray crystallographic and infrared spectral study demonstrates CO binding to Cu(B). Biochim.Biophys.Acta, 1817, 2012
|
|
3QJS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qjs by Molmil](/molmil-images/mine/3qjs) | The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus | Descriptor: | CARBON MONOXIDE, COPPER (I) ION, Cytochrome c oxidase polypeptide 2A, ... | Authors: | Liu, B, Zhang, Y, Sage, J.T, Doukov, T, Chen, Y, Stout, C.D, Fee, J.A. | Deposit date: | 2011-01-30 | Release date: | 2012-01-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural changes that occur upon photolysis of the Fe(II)(a3)-CO complex in the cytochrome ba(3)-oxidase of Thermus thermophilus: A combined X-ray crystallographic and infrared spectral study demonstrates CO binding to Cu(B). Biochim.Biophys.Acta, 1817, 2012
|
|
1QHB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qhb by Molmil](/molmil-images/mine/1qhb) | VANADIUM BROMOPEROXIDASE FROM RED ALGA CORALLINA OFFICINALIS | Descriptor: | CALCIUM ION, HALOPEROXIDASE, PHOSPHATE ION | Authors: | Isupov, M.N, Dalby, A.R, Brindley, A.A, Littlechild, J.A. | Deposit date: | 1999-05-11 | Release date: | 2000-07-05 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of dodecameric vanadium-dependent bromoperoxidase from the red algae Corallina officinalis. J.Mol.Biol., 299, 2000
|
|
3QJQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qjq by Molmil](/molmil-images/mine/3qjq) | The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus | Descriptor: | CARBON MONOXIDE, COPPER (I) ION, Cytochrome c oxidase polypeptide 2A, ... | Authors: | Liu, B, Zhang, Y, Sage, J.T, Doukov, T, Chen, Y, Stout, C.D, Fee, J.A. | Deposit date: | 2011-01-30 | Release date: | 2012-01-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural changes that occur upon photolysis of the Fe(II)(a3)-CO complex in the cytochrome ba(3)-oxidase of Thermus thermophilus: A combined X-ray crystallographic and infrared spectral study demonstrates CO binding to Cu(B). Biochim.Biophys.Acta, 1817, 2012
|
|