2J8A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2j8a by Molmil](/molmil-images/mine/2j8a) | X-ray structure of the N-terminus RRM domain of Set1 | Descriptor: | HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-4 SPECIFIC | Authors: | Tresaugues, L, Dehe, P.M, Guerois, R, Rodriguez-Gil, A, Varlet, I, Salah, P, Pamblanco, M, Luciano, P, Quevillon-Cheruel, S, Sollier, J, Leulliot, N, Couprie, J, Tordera, V, Zinn-Justin, S, Chavez, S, Van Tilbeurgh, H, Geli, V. | Deposit date: | 2006-10-24 | Release date: | 2007-03-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | X-Ray Structure of the N-Terminus Rrm Domain of Set1 To be Published
|
|
1S9J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s9j by Molmil](/molmil-images/mine/1s9j) | X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a complex with ligand and MgATP | Descriptor: | 5-BROMO-N-(2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-[(2-FLUORO-4-IODOPHENYL)AMINO]BENZAMIDE, ADENOSINE-5'-TRIPHOSPHATE, Dual specificity mitogen-activated protein kinase kinase 1, ... | Authors: | Ohren, J.F, Chen, H, Pavlovsky, A, Whitehead, C, Yan, C, McConnell, P, Delaney, A, Dudley, D.T, Sebolt-Leopold, J, Hasemann, C.A. | Deposit date: | 2004-02-04 | Release date: | 2004-11-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition. Nat.Struct.Mol.Biol., 11, 2004
|
|
4OE1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oe1 by Molmil](/molmil-images/mine/4oe1) | Crystal structure of the pentatricopeptide repeat protein PPR10 (C256S/C430S/C449S) in complex with an 18-nt PSAJ rna element | Descriptor: | Chloroplast pentatricopeptide repeat protein 10, PHOSPHATE ION, psaJ RNA | Authors: | Li, Q, Yan, C, Wu, J, Yin, P, Yan, N. | Deposit date: | 2014-01-11 | Release date: | 2014-09-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Examination of the dimerization states of the single-stranded RNA recognition protein pentatricopeptide repeat 10 (PPR10). J.Biol.Chem., 289, 2014
|
|
8GXX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gxx by Molmil](/molmil-images/mine/8gxx) | 3 nucleotide-bound V1EG of V/A-ATPase from Thermus thermophilus. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Nakanishi, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | Deposit date: | 2022-09-21 | Release date: | 2023-01-25 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding. J.Biol.Chem., 299, 2023
|
|
7NBN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nbn by Molmil](/molmil-images/mine/7nbn) | Allostery through DNA drives phenotype switching | Descriptor: | AddAB promoter | Authors: | Rosenblum, G, Elad, N, Rozenberg, H, Wiggers, F, Jungwirth, J, Hofmann, H. | Deposit date: | 2021-01-27 | Release date: | 2021-04-07 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Allostery through DNA drives phenotype switching. Nat Commun, 12, 2021
|
|
8GXU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gxu by Molmil](/molmil-images/mine/8gxu) | 1 ATP-bound V1EG of V/A-ATPase from Thermus thermophilus | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, SULFATE ION, V-type ATP synthase alpha chain, ... | Authors: | Nakanishi, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | Deposit date: | 2022-09-21 | Release date: | 2023-01-25 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding. J.Biol.Chem., 299, 2023
|
|
8GXY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gxy by Molmil](/molmil-images/mine/8gxy) | 2 sulfate-bound V1EG of V/A-ATPase from Thermus thermophilus. | Descriptor: | SULFATE ION, V-type ATP synthase alpha chain, V-type ATP synthase beta chain, ... | Authors: | Nakanishi, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | Deposit date: | 2022-09-21 | Release date: | 2023-01-25 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding. J.Biol.Chem., 299, 2023
|
|
7NEZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nez by Molmil](/molmil-images/mine/7nez) | Structure of topotecan-bound ABCG2 | Descriptor: | (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, ... | Authors: | Kowal, J, Locher, K, Ni, D, Stahlberg, H. | Deposit date: | 2021-02-05 | Release date: | 2021-04-21 | Last modified: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2. J.Mol.Biol., 433, 2021
|
|
5ZT0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zt0 by Molmil](/molmil-images/mine/5zt0) | |
4O98
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o98 by Molmil](/molmil-images/mine/4o98) | Crystal structure of Pseudomonas oleovorans PoOPH mutant H250I/I263W | Descriptor: | ZINC ION, organophosphorus hydrolase | Authors: | Luo, X.J, Kong, X.D, Zhao, J, Chen, Q, Zhou, J.H, Xu, J.H. | Deposit date: | 2014-01-02 | Release date: | 2014-12-03 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.251 Å) | Cite: | Switching a newly discovered lactonase into an efficient and thermostable phosphotriesterase by simple double mutations His250Ile/Ile263Trp Biotechnol.Bioeng., 111, 2014
|
|
7NFD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nfd by Molmil](/molmil-images/mine/7nfd) | Structure of mitoxantrone-bound ABCG2 | Descriptor: | 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, ... | Authors: | Kowal, J, Locher, K, Ni, D, Stahlberg, H. | Deposit date: | 2021-02-06 | Release date: | 2021-04-21 | Last modified: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2. J.Mol.Biol., 433, 2021
|
|
8GXZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gxz by Molmil](/molmil-images/mine/8gxz) | 1 sulfate and 1 ATP bound V1EG of V/A-ATPase from Thermus thermophilus. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SULFATE ION, ... | Authors: | Nakanishi, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | Deposit date: | 2022-09-21 | Release date: | 2023-01-25 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding. J.Biol.Chem., 299, 2023
|
|
8GXW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gxw by Molmil](/molmil-images/mine/8gxw) | 2 ATP-bound V1EG of V/A-ATPase from Thermus thermophilus | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SULFATE ION, ... | Authors: | Nakanishi, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | Deposit date: | 2022-09-21 | Release date: | 2023-01-25 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding. J.Biol.Chem., 299, 2023
|
|
4CMD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4cmd by Molmil](/molmil-images/mine/4cmd) | The (R)-selective transaminase from Nectria haematococca | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Sayer, C, Isupov, M, Martinez-Torres, R.J, Richter, N, Hailes, H.C, Ward, J, Littlechild, J. | Deposit date: | 2014-01-16 | Release date: | 2014-03-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | The Substrate Specificity, Enantioselectivity and Structure of the (R)-Selective Amine:Pyruvate Transaminase from Nectria Haematococca. FEBS J., 281, 2014
|
|
7NEQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7neq by Molmil](/molmil-images/mine/7neq) | Structure of tariquidar-bound ABCG2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... | Authors: | Kowal, J, Locher, K. | Deposit date: | 2021-02-04 | Release date: | 2021-04-21 | Last modified: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2. J.Mol.Biol., 433, 2021
|
|
5ZWX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zwx by Molmil](/molmil-images/mine/5zwx) | |
2LVF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lvf by Molmil](/molmil-images/mine/2lvf) | Solution structure of the Brazil Nut 2S albumin Ber e 1 | Descriptor: | 2S albumin | Authors: | Rundqvist, L, Tengel, T, Zdunek, J, Schleucher, J, Alcocer, M.J, Larsson, G. | Deposit date: | 2012-07-04 | Release date: | 2012-10-17 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution structure, copper binding and backbone dynamics of recombinant Ber e 1-the major allergen from Brazil nut. Plos One, 7, 2012
|
|
1E99
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1e99 by Molmil](/molmil-images/mine/1e99) | Human thymidylate kinase complexed with AZTMP and ADP | Descriptor: | 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reinstein, J, Goody, R.S, Konrad, M, Schlichting, I. | Deposit date: | 2000-10-10 | Release date: | 2001-10-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
|
|
1E9F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1e9f by Molmil](/molmil-images/mine/1e9f) | Mutant human thymidylate kinase complexed with TMP and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, THYMIDINE-5'-PHOSPHATE, ... | Authors: | Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reinstein, J, Goody, R.S, Konrad, M, Schlichting, I. | Deposit date: | 2000-10-11 | Release date: | 2001-10-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
|
|
1E98
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1e98 by Molmil](/molmil-images/mine/1e98) | Wild type human thymidylate kinase complexed with AZTMP and ADP | Descriptor: | 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reintein, J, Goody, R.S, Konrad, M, Schlichting, I. | Deposit date: | 2000-10-10 | Release date: | 2001-10-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
|
|
7NL5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nl5 by Molmil](/molmil-images/mine/7nl5) | Structure of the catalytic domain of the Bacillus circulans alpha-1,6 Mannanase in complex with an alpha-1,6-alpha-manno-cyclophellitol trisaccharide inhibitor | Descriptor: | (1R,2R,3R,4S,5R)-4-(hydroxymethyl)cyclohexane-1,2,3,5-tetrol, (1R,6S)-5beta-(Hydroxymethyl)-7-oxabicyclo[4.1.0]heptane-2beta,3beta,4alpha-triol, Alpha-1,6-mannanase, ... | Authors: | Schroeder, S, Offen, W.A, Males, A, Jin, Y, De Boer, C, Enotarpi, J, Marino, L, van der Marel, G.A, Florea, B.I, Codee, J.D.C, Overkleeft, H.S, Davies, G.J. | Deposit date: | 2021-02-22 | Release date: | 2021-04-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Development of Non-Hydrolysable Oligosaccharide Activity-Based Inactivators for Endoglycanases: A Case Study on alpha-1,6 Mannanases. Chemistry, 27, 2021
|
|
1E9B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1e9b by Molmil](/molmil-images/mine/1e9b) | Human thymidylate kinase complexed with AZTMP and APPNP | Descriptor: | 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reintein, J, Goody, R.S, Konrad, M, Schlichting, I. | Deposit date: | 2000-10-10 | Release date: | 2001-10-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
|
|
1SPW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1spw by Molmil](/molmil-images/mine/1spw) | Solution Structure of a Loop Truncated Mutant from D. gigas Rubredoxin, NMR | Descriptor: | Rubredoxin | Authors: | Pais, T.M, Lamosa, P, dos Santos, W, LeGall, J, Turner, D.L, Santos, H. | Deposit date: | 2004-03-17 | Release date: | 2005-03-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural determinants of protein stabilization by solutes: the importance of the hairpin loop in rubredoxins FEBS J., 272, 2005
|
|
4D25
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4d25 by Molmil](/molmil-images/mine/4d25) | Crystal structure of the Bombyx mori Vasa helicase (E339Q) in complex with RNA and AMPPNP | Descriptor: | 5'-R(*UP*GP*AP*CP*AP*UP)-3', BMVLG PROTEIN, GLYCEROL, ... | Authors: | Spinelli, P, Pillai, R.S, Kadlec, J, Cusack, S. | Deposit date: | 2014-05-07 | Release date: | 2014-06-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | RNA Clamping by Vasa Assembles a Pirna Amplifier Complex on Transposon Transcripts. Cell(Cambridge,Mass.), 157, 2014
|
|
4D4S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4d4s by Molmil](/molmil-images/mine/4d4s) | Focal Adhesion Kinase catalytic domain | Descriptor: | 2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE, DIMETHYL SULFOXIDE, FOCAL ADHESION KINASE 1, ... | Authors: | Le Coq, J, Lin, A, Lietha, D. | Deposit date: | 2014-10-31 | Release date: | 2015-02-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Allosteric Regulation of Focal Adhesion Kinase by Pip2 and ATP. Biophys.J., 108, 2015
|
|