6I0D
 
 | | Respiratory complex I from Thermus thermophilus with bound Decyl-Ubiquinone | | 分子名称: | 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A. | | 登録日 | 2018-10-25 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Key role of quinone in the mechanism of respiratory complex I.
Nat Commun, 11, 2020
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6HBK
 | | Echovirus 18 Open particle without one pentamer | | 分子名称: | Echovirus 18 capsid protein 1, Echovirus 18 capsid protein 2, Echovirus 18 capsid protein 3 | | 著者 | Buchta, D, Fuzik, T, Hrebik, D, Levdansky, Y, Moravcova, J, Plevka, P. | | 登録日 | 2018-08-10 | | 公開日 | 2019-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Enterovirus particles expel capsid pentamers to enable genome release.
Nat Commun, 10, 2019
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6HCE
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5JQ7
 | | Crystal structure of Ebola glycoprotein in complex with toremifene | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, Envelope glycoprotein 1,Envelope glycoprotein 1,Envelope glycoprotein 1, ... | | 著者 | Zhao, Y, Ren, J, Stuart, D.I. | | 登録日 | 2016-05-04 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Toremifene interacts with and destabilizes the Ebola virus glycoprotein.
Nature, 535, 2016
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1HT2
 | | Nucleotide-Dependent Conformational Changes in a Protease-Associated ATPase HslU | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, HEAT SHOCK LOCUS HSLU, HEAT SHOCK LOCUS HSLV | | 著者 | Wang, J, Song, J.J, Seong, I.S, Franklin, M.C, Kamtekar, S, Eom, S.H, Chung, C.H. | | 登録日 | 2000-12-27 | | 公開日 | 2001-11-14 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Nucleotide-dependent conformational changes in a protease-associated ATPase HsIU.
Structure, 9, 2001
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2LKH
 | | WSA minor conformation | | 分子名称: | Acetylcholine receptor | | 著者 | Xu, Y, Mowrey, D, Cui, T, Perez-Aguilar, J, Saven, J.G, Eckenhoff, R, Tang, P. | | 登録日 | 2011-10-11 | | 公開日 | 2012-01-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure and dynamics of a designed water-soluble transmembrane domain of nicotinic acetylcholine receptor.
Biochim.Biophys.Acta, 1818, 2011
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6I8D
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1DCU
 | | REDOX SIGNALING IN THE CHLOROPLAST: STRUCTURE OF OXIDIZED PEA FRUCTOSE-1,6-BISPHOSPHATE PHOSPHATASE | | 分子名称: | FRUCTOSE-1,6-BISPHOSPHATASE | | 著者 | Chiadmi, M, Navaza, A, Miginiac-Maslow, M, Jacquot, J.P, Cherfils, J. | | 登録日 | 1999-11-05 | | 公開日 | 1999-12-03 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Redox signalling in the chloroplast: structure of oxidized pea fructose-1,6-bisphosphate phosphatase.
EMBO J., 18, 1999
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2QV0
 | | Crystal structure of the response regulatory domain of protein mrkE from Klebsiella pneumoniae | | 分子名称: | Protein mrkE | | 著者 | Bonanno, J.B, Freeman, J, Bain, K.T, Iizuka, I, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2007-08-07 | | 公開日 | 2007-08-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of the response regulatory domain of protein mrkE from Klebsiella pneumoniae.
To be Published
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2QWR
 | | Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-394aa)R171C and bovine Auxilin (810-910aa)D876C in the AMPPNP intact form | | 分子名称: | ACETIC ACID, GLYCEROL, Heat shock cognate 71 kDa protein, ... | | 著者 | Jiang, J, Maes, E.G, Wang, L, Taylor, A.B, Hinck, A.P, Lafer, E.M, Sousa, R. | | 登録日 | 2007-08-10 | | 公開日 | 2007-12-18 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structural basis of J cochaperone binding and regulation of Hsp70.
Mol.Cell, 28, 2007
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6I80
 | | Crystal Structure of the second bromodomain of BRD2 in complex with RT53 | | 分子名称: | 1,2-ETHANEDIOL, 2-[(4~{S})-6-(4-chlorophenyl)-8-methoxy-1-methyl-4~{H}-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-1-[4-(dimethylamino)piperidin-1-yl]ethanone, Bromodomain-containing protein 2 | | 著者 | Picaud, S, Traquete, R, Bernardes, G.J.L, Newman, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Filippakopoulos, P, Structural Genomics Consortium (SGC) | | 登録日 | 2018-11-19 | | 公開日 | 2019-11-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | | 主引用文献 | Crystal Structure of the second bromodomain of BRD2 in complex with RT53
To Be Published
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6IDI
 | | Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 8.0. | | 分子名称: | Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ... | | 著者 | Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M. | | 登録日 | 2018-09-10 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (12 Å) | | 主引用文献 | Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody.
Structure, 27, 2019
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2QVS
 | | Crystal Structure of Type IIa Holoenzyme of cAMP-dependent Protein Kinase | | 分子名称: | cAMP-dependent protein kinase type II-alpha regulatory subunit, cAMP-dependent protein kinase, alpha-catalytic subunit | | 著者 | Wu, J, Brown, S.H.J, von Daake, S, Taylor, S.S. | | 登録日 | 2007-08-08 | | 公開日 | 2007-10-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | PKA type IIalpha holoenzyme reveals a combinatorial strategy for isoform diversity.
Science, 318, 2007
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6IDV
 | | Peptide Asparaginyl Ligases from Viola yedoensis | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | El Sahili, A, Hu, S, Lescar, J. | | 登録日 | 2018-09-11 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural determinants for peptide-bond formation by asparaginyl ligases.
Proc.Natl.Acad.Sci.USA, 116, 2019
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5K9S
 | | Importin-alpha in complex with HNF1-beta peptide | | 分子名称: | HNF1 beta A splice variant 2, Importin subunit alpha-1 | | 著者 | Wiedmann, M.M, Aibara, S, Spring, D.R, Stewart, M, Brenton, J. | | 登録日 | 2016-06-01 | | 公開日 | 2016-11-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Importin-alpha in complex with HNF1-beta peptide
To Be Published
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2QWO
 | | Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-394aa)R171C and bovine Auxilin (810-910aa)D876C in the ADP*Pi form #1 | | 分子名称: | ACETIC ACID, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | | 著者 | Jiang, J, Maes, E.G, Wang, L, Taylor, A.B, Hinck, A.P, Lafer, E.M, Sousa, R. | | 登録日 | 2007-08-10 | | 公開日 | 2007-12-18 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis of J cochaperone binding and regulation of Hsp70.
Mol.Cell, 28, 2007
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2LRD
 | | The solution structure of the monomeric Acanthaporin | | 分子名称: | Acanthaporin | | 著者 | Michalek, M, Soennichsen, F.D, Wechselberger, R, Dingley, A.J, Wienk, H, Simanski, M, Herbst, R, Lorenzen, I, Marciano-Cabral, F, Gelhaus, C, Groetzinger, J, Leippe, M. | | 登録日 | 2012-03-28 | | 公開日 | 2012-05-02 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and function of a unique pore-forming protein from a pathogenic acanthamoeba.
Nat.Chem.Biol., 9, 2013
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5KBT
 | | Cryo-EM structure of GluA2-1xSTZ complex at 6.4 Angstrom resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | | 著者 | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | | 登録日 | 2016-06-03 | | 公開日 | 2016-07-13 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (6.4 Å) | | 主引用文献 | Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy.
Science, 353, 2016
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6I1O
 | | Fab fragment of an antibody selective for wild-type alpha-1-antitrypsin | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FAB 2H2 heavy chain, FAB 2H2 light chain, ... | | 著者 | Laffranchi, M, Elliston, E.L.K, Miranda, E, Perez, J, Fra, A, Lomas, D.A, Irving, J.A. | | 登録日 | 2018-10-29 | | 公開日 | 2019-11-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin.
JCI Insight, 5, 2020
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6IDK
 | | Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 5.0 (Class I particle) | | 分子名称: | Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ... | | 著者 | Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M. | | 登録日 | 2018-09-10 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (25 Å) | | 主引用文献 | Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody.
Structure, 27, 2019
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6IES
 | | Onion lachrymatory factor synthase (LFS) containing (E)-2-propen 1-ol (crotyl alcohol) | | 分子名称: | (2E)-but-2-en-1-ol, Lachrymatory-factor synthase | | 著者 | Sato, Y, Arakawa, T, Takabe, J, Masamura, N, Tsuge, N, Imai, S, Fushinobu, S. | | 登録日 | 2018-09-17 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Dissecting the Stereocontrolled Conversion of Short-Lived Sulfenic Acid by Lachrymatory Factor Synthase.
Acs Catalysis, 10, 2020
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2QE7
 | | Crystal structure of the f1-atpase from the thermoalkaliphilic bacterium bacillus sp. ta2.a1 | | 分子名称: | ATP synthase subunit alpha, ATP synthase subunit beta, ATP synthase subunit epsilon, ... | | 著者 | Stocker, A, Keis, S, Vonck, J, Cook, G.M, Dimroth, P. | | 登録日 | 2007-06-25 | | 公開日 | 2007-08-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | | 主引用文献 | The Structural Basis for Unidirectional Rotation of Thermoalkaliphilic F(1)-ATPase.
Structure, 15, 2007
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5KE0
 | | Discovery of 1-1H-Pyrazolo 4,3-c pyridine-6-yl urea Inhibitors of Extracellular Signal Regulated Kinase ERK for the Treatment of Cancers | | 分子名称: | 1-[3-(2-methylpyridin-4-yl)-1~{H}-pyrazolo[4,3-c]pyridin-6-yl]-3-(phenylmethyl)urea, Mitogen-activated protein kinase 1, SULFATE ION | | 著者 | Hruza, A, Lim, J. | | 登録日 | 2016-06-09 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Discovery of 1-(1H-Pyrazolo[4,3-c]pyridin-6-yl)urea Inhibitors of Extracellular Signal-Regulated Kinase (ERK) for the Treatment of Cancers.
J.Med.Chem., 59, 2016
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2R28
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2QGG
 | | X-Ray structure of the protein Q6F7I0 from Acinetobacter calcoaceticus AmMS 248. Northeast Structural Genomics Consortium target AsR73. | | 分子名称: | 16S rRNA-processing protein rimM, POTASSIUM ION, UNKNOWN LIGAND | | 著者 | Kuzin, A.P, Su, M, Jayaraman, S, Wang, D, Janjua, H, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2007-06-28 | | 公開日 | 2007-07-17 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-Ray structure of the protein Q6F7I0 from Acinetobacter calcoaceticus AmMS 248.
To be Published
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