3AI8
| Cathepsin B in complex with the nitroxoline | 分子名称: | 5-nitroquinolin-8-ol, Cathepsin B | 著者 | Renko, M, Mirkovic, B, Gobec, S, Kos, J, Turk, D. | 登録日 | 2010-05-11 | 公開日 | 2011-05-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Novel mechanism of cathepsin B inhibition by antibiotic nitroxoline and related compounds Chemmedchem, 6, 2011
|
|
6MYY
| Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 3 Fabs bound, sharpened map | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ... | 著者 | Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D. | 登録日 | 2018-11-02 | 公開日 | 2018-11-14 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core. Elife, 7, 2018
|
|
2BB6
| Structure of Cobalamin-complexed Bovine Transcobalamin in Monoclinic Crystal Form | 分子名称: | CHLORIDE ION, COBALAMIN, Transcobalamin II | 著者 | Wuerges, J, Garau, G, Geremia, S, Fedosov, S.N, Petersen, T.E, Randaccio, L. | 登録日 | 2005-10-17 | 公開日 | 2006-04-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for mammalian vitamin B12 transport by transcobalamin. Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
3AKN
| |
1N6G
| The structure of immature Dengue-2 prM particles | 分子名称: | major envelope protein E | 著者 | Zhang, Y, Corver, J, Chipman, P.R, Zhang, W, Pletnev, S.V, Sedlak, D, Baker, T.S, Strauss, J.H, Kuhn, R.J, Rossmann, M.G. | 登録日 | 2002-11-10 | 公開日 | 2003-06-03 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (16 Å) | 主引用文献 | Structures of Immature flavivirus particles EMBO J., 22, 2003
|
|
2AGL
| Crystal structure of the phenylhydrazine adduct of aromatic amine dehydrogenase from Alcaligenes faecalis | 分子名称: | 1-PHENYLHYDRAZINE, Aromatic amine dehydrogenase | 著者 | Masgrau, L, Roujeinikova, A, Johannissen, L.O, Hothi, P, Basran, J, Ranaghan, K.E, Mulholland, A.J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. | 登録日 | 2005-07-27 | 公開日 | 2006-04-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Atomic description of an enzyme reaction dominated by proton tunneling Science, 312, 2006
|
|
3ALM
| Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, mutant C294A | 分子名称: | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL | 著者 | Kobayashi, J, Yoshida, H, Yoshikane, Y, Kamitori, S, Yagi, T. | 登録日 | 2010-08-04 | 公開日 | 2011-08-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase To be Published
|
|
2AGY
| Crystal structure of the Schiff base intermediate in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with tryptamine. Monoclinic form | 分子名称: | 2-(1H-INDOL-3-YL)ETHANIMINE, Aromatic amine dehydrogenase | 著者 | Masgrau, L, Roujeinikova, A, Johannissen, L.O, Hothi, P, Basran, J, Ranaghan, K.E, Mulholland, A.J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. | 登録日 | 2005-07-27 | 公開日 | 2006-04-25 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Atomic description of an enzyme reaction dominated by proton tunneling Science, 312, 2006
|
|
6NWO
| Structures of the transcriptional regulator BgaR, a lactose sensor. | 分子名称: | CHLORIDE ION, GLYCEROL, Transcriptional regulator BgaR, ... | 著者 | Peat, T.S, Newman, J. | 登録日 | 2019-02-06 | 公開日 | 2019-07-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Structures of the transcriptional regulator BgaR, a lactose sensor. Acta Crystallogr D Struct Biol, 75, 2019
|
|
6NX3
| |
1JQ4
| [2Fe-2S] Domain of Methane Monooxygenase Reductase from Methylococcus capsulatus (Bath) | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, METHANE MONOOXYGENASE COMPONENT C | 著者 | Mueller, J, Lugovskoy, A.A, Wagner, G, Lippard, S.J. | 登録日 | 2001-08-03 | 公開日 | 2002-01-09 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of the [2Fe-2S] ferredoxin domain from soluble methane monooxygenase reductase and interaction with its hydroxylase. Biochemistry, 41, 2002
|
|
2AI8
| E.coli Polypeptide Deformylase complexed with SB-485343 | 分子名称: | NICKEL (II) ION, Peptide deformylase, [HYDROXY(3-PHENYLPROPYL)AMINO]METHANOL | 著者 | Smith, K.J, Petit, C.M, Aubart, K, Smyth, M, McManus, E, Jones, J, Fosberry, A, Lewis, C, Lonetto, M, Christensen, S.B. | 登録日 | 2005-07-29 | 公開日 | 2005-09-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Variation and inhibitor binding in polypeptide deformylase from four different bacterial species. Protein Sci., 12, 2003
|
|
6NXI
| Flavin Transferase ApbE from Vibrio cholerae | 分子名称: | 1,2-ETHANEDIOL, FAD:protein FMN transferase, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Osipiuk, J, Fang, X, Chakravarthy, S, Juarez, O, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-02-08 | 公開日 | 2019-03-13 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Conserved residue His-257 ofVibrio choleraeflavin transferase ApbE plays a critical role in substrate binding and catalysis. J.Biol.Chem., 294, 2019
|
|
2ALE
| Crystal structure of yeast RNA splicing factor Snu13p | 分子名称: | MAGNESIUM ION, NHP2/L7aE family protein YEL026W | 著者 | Dobbyn, H.C, McEwan, P.A, Bella, J, O'Keefe, R.T. | 登録日 | 2005-08-05 | 公開日 | 2006-10-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Analysis of pre-mRNA and pre-rRNA processing factor Snu13p structure and mutants. Biochem.Biophys.Res.Commun., 360, 2007
|
|
5TEU
| Brucella periplasmic binding protein YehZ | 分子名称: | ACETATE ION, L(+)-TARTARIC ACID, SULFATE ION, ... | 著者 | Herrou, J, Crosson, S. | 登録日 | 2016-09-22 | 公開日 | 2017-01-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Conserved ABC Transport System Regulated by the General Stress Response Pathways of Alpha- and Gammaproteobacteria. J. Bacteriol., 199, 2017
|
|
1N78
| Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with tRNA(Glu) and glutamol-AMP. | 分子名称: | GLUTAMOL-AMP, Glutamyl-tRNA synthetase, MAGNESIUM ION, ... | 著者 | Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-11-13 | 公開日 | 2003-02-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding EMBO J., 22, 2003
|
|
3ATI
| Crystal structure of trypsin complexed with (3-methoxyphenyl)methanamine | 分子名称: | 1-(3-methoxyphenyl)methanamine, CALCIUM ION, Cationic trypsin, ... | 著者 | Yamane, J, Yao, M, Tanaka, I. | 登録日 | 2011-01-05 | 公開日 | 2011-08-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | In-crystal affinity ranking of fragment hit compounds reveals a relationship with their inhibitory activities J.Appl.Crystallogr., 44, 2011
|
|
1G0V
| THE STRUCTURE OF PROTEINASE A COMPLEXED WITH A IA3 MUTANT, MVV | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEASE A INHIBITOR 3, PROTEINASE A, ... | 著者 | Phylip, L.H, Lees, W, Brownsey, B.G, Bur, D, Dunn, B.M, Winther, J, Gustchina, A, Li, M, Copeland, T, Wlodawer, A, Kay, J. | 登録日 | 2000-10-09 | 公開日 | 2001-04-21 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The potency and specificity of the interaction between the IA3 inhibitor and its target aspartic proteinase from Saccharomyces cerevisiae. J.Biol.Chem., 276, 2001
|
|
6NHJ
| Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development | 分子名称: | Major capsid protein, Minor capsid protein, Small capsomere-interacting protein, ... | 著者 | Liu, W, Dai, X.H, Jih, J, Chan, K, Trang, P, Yu, X.K, Balogun, R, Mei, Y, Liu, F.Y, Zhou, Z.H. | 登録日 | 2018-12-22 | 公開日 | 2019-03-06 | 最終更新日 | 2019-11-27 | 実験手法 | ELECTRON MICROSCOPY (5 Å) | 主引用文献 | Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development. PLoS Pathog., 15, 2019
|
|
1NA4
| The structure of immature Yellow Fever virus particle | 分子名称: | major envelope protein E | 著者 | Zhang, Y, Corver, J, Chipman, P.R, Lenches, E, Zhang, W, Pletnev, S.V, Sedlak, D, Baker, T.S, Strauss, J.H, Kuhn, R.J, Rossmann, M.G. | 登録日 | 2002-11-26 | 公開日 | 2003-12-09 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY | 主引用文献 | Structures of immature flavivirus particles EMBO J., 22, 2003
|
|
2ATP
| Crystal structure of a CD8ab heterodimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 beta chain, ... | 著者 | Chang, H.C, Tan, K, Ouyang, J, Parisini, E, Liu, J.H, Le, Y, Wang, X, Reinherz, E.L, Wang, J.H. | 登録日 | 2005-08-25 | 公開日 | 2005-12-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and Mutational Analyses of a CD8alphabeta Heterodimer and Comparison with the CD8alphaalpha Homodimer. Immunity, 23, 2005
|
|
3AR3
| Calcium pump crystal structure with bound ADP and TG | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ... | 著者 | Toyoshima, C, Yonekura, S, Tsueda, J, Iwasawa, S. | 登録日 | 2010-11-24 | 公開日 | 2011-02-02 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Trinitrophenyl derivatives bind differently from parent adenine nucleotides to Ca2+-ATPase in the absence of Ca2+ Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
4KPU
| Electron transferring flavoprotein of Acidaminococcus fermentans: Towards a mechanism of flavin-based electron bifurcation | 分子名称: | CHLORIDE ION, Electron transfer flavoprotein alpha subunit, Electron transfer flavoprotein alpha/beta-subunit, ... | 著者 | Mowafy, A.M, Chowdhury, N.P, Demmer, J, Upadhyay, V, Kolzer, S, Jayamani, E, Kahnt, J, Demmer, U, Ermler, U, Buckel, W. | 登録日 | 2013-05-14 | 公開日 | 2014-01-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Studies on the Mechanism of Electron Bifurcation Catalyzed by Electron Transferring Flavoprotein (Etf) and Butyryl-CoA Dehydrogenase (Bcd) of Acidaminococcus fermentans. J.Biol.Chem., 289, 2014
|
|
2AVM
| Kinetics, stability, and structural changes in high resolution crystal structures of HIV-1 protease with drug resistant mutations L24I, I50V, AND G73S | 分子名称: | ACETIC ACID, GLYCEROL, HIV-1 protease, ... | 著者 | Liu, F, Boross, P.I, Wang, Y.F, Tozser, J, Louis, J.M, Harrison, R.W, Weber, I.T. | 登録日 | 2005-08-30 | 公開日 | 2006-01-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S. J.Mol.Biol., 354, 2005
|
|
5TKC
| Crystal structure of FBP aldolase from Toxoplasma gondii, ternary complex | 分子名称: | 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-bisphosphate aldolase, GLYCERALDEHYDE-3-PHOSPHATE, ... | 著者 | Heron, P.W, Sygusch, J. | 登録日 | 2016-10-06 | 公開日 | 2017-10-04 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (1.779 Å) | 主引用文献 | Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases. J. Biol. Chem., 292, 2017
|
|