4X3Z
 
 | | Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, in complex with XMP and NAD | | 分子名称: | GLYCEROL, Inosine-5'-monophosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Osipiuk, J, MALTSEVA, N, KIM, Y, Mulligan, R, MAKOWSKA-GRZYSKA, M, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2014-12-02 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, in complex with XMP and NAD
to be published
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1N5U
 | | X-RAY STUDY OF HUMAN SERUM ALBUMIN COMPLEXED WITH HEME | | 分子名称: | MYRISTIC ACID, PROTOPORPHYRIN IX CONTAINING FE, SERUM ALBUMIN | | 著者 | Wardell, M, Wang, Z, Ho, J.X, Robert, J, Ruker, F, Ruble, J, Carter, D.C. | | 登録日 | 2002-11-07 | | 公開日 | 2003-06-24 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Atomic Structure of Human Methemalbumin at 1.9 A
Biochem.Biophys.Res.Commun., 291, 2002
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4X6B
 | | BK6 TCR apo structure | | 分子名称: | TCR alpha, TCR beta | | 著者 | Birkinshaw, R.W, Rossjohn, J. | | 登録日 | 2014-12-07 | | 公開日 | 2015-01-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | alpha beta T cell antigen receptor recognition of CD1a presenting self lipid ligands.
Nat.Immunol., 16, 2015
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4X6I
 | | Development of N-(Functionalized benzoyl)-homocycloleucyl-glycinonitriles as Potent Cathepsin K Inhibitors. | | 分子名称: | 2-amino-4-bromo-N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}benzamide, Cathepsin K, SULFATE ION | | 著者 | Borisek, J, Mohar, B, Vizovisek, M, Sosnowski, P, Turk, D, Turk, B, Novic, M. | | 登録日 | 2014-12-08 | | 公開日 | 2015-09-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Development of N-(Functionalized benzoyl)-homocycloleucyl-glycinonitriles as Potent Cathepsin K Inhibitors.
J.Med.Chem., 58, 2015
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1UYN
 | | Translocator domain of autotransporter NalP from Neisseria meningitidis | | 分子名称: | NALP, PENTAETHYLENE GLYCOL MONODECYL ETHER, SULFATE ION | | 著者 | Oomen, C.J, Van Ulsen, P, Van Gelder, P, Feijen, M, Tommassen, J, Gros, P. | | 登録日 | 2004-03-02 | | 公開日 | 2004-03-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of the Translocator Domain of a Bacterial Autotransporter
Embo J., 23, 2004
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1HAI
 | | THE ISOMORPHOUS STRUCTURES OF PRETHROMBIN2, HIRUGEN-AND PPACK-THROMBIN: CHANGES ACCOMPANYING ACTIVATION AND EXOSITE BINDING TO THROMBIN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ... | | 著者 | Tulinsky, A, Vijayalakshmi, J. | | 登録日 | 1994-06-27 | | 公開日 | 1994-12-20 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin.
Protein Sci., 3, 1994
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4WM8
 | | Crystal Structure of Human Enterovirus D68 | | 分子名称: | DECANOIC ACID, VP1, VP2, ... | | 著者 | Liu, Y, Sheng, J, Fokine, A, Meng, G, Long, F, Kuhn, R.J, Rossmann, M.G. | | 登録日 | 2014-10-08 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Virus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children.
Science, 347, 2015
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8EYZ
 | | Engineered glutamine binding protein bound to GLN and a cobaloxime ligand | | 分子名称: | AZIDOBIS (DIMETHYLGLYOXIMATO) PYRIDINECOBALT, Amino acid ABC transporter substrate-binding protein, GLUTAMINE, ... | | 著者 | Bridwell-Rabb, J, Boggs, D.G, Olshansky, L, Fatima, S, Thompson, P. | | 登録日 | 2022-10-29 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Engineering a Conformationally Switchable Artificial Metalloprotein.
J.Am.Chem.Soc., 144, 2022
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1CON
 | | THE REFINED STRUCTURE OF CADMIUM SUBSTITUTED CONCANAVALIN A AT 2.0 ANGSTROMS RESOLUTION | | 分子名称: | CADMIUM ION, CALCIUM ION, CONCANAVALIN A | | 著者 | Naismith, J.H, Habash, J, Harrop, S.J, Helliwell, J.R, Hunter, W.N, Kalb(Gilboa), A.J, Yariv, J, Wan, T.C.M, Weisgerber, S. | | 登録日 | 1993-03-16 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Refined structure of cadmium-substituted concanavalin A at 2.0 A resolution.
Acta Crystallogr.,Sect.D, 49, 1993
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5T5H
 | | Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit | | 分子名称: | 40S ribosomal protein L14, 5.8S rRNA, 5S rRNA, ... | | 著者 | Liu, Z, Gutierrez-Vargas, C, Wei, J, Grassucci, R.A, Ramesh, M, Espina, N, Sun, M, Tutuncuoglu, B, Madison-Antenucci, S, Woolford Jr, J.L, Tong, L, Frank, J. | | 登録日 | 2016-08-31 | | 公開日 | 2016-10-12 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | | 主引用文献 | Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit.
Proc.Natl.Acad.Sci.USA, 113, 2016
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8EVC
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8EV8
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4C3D
 | | HRSV M2-1, P422 crystal form | | 分子名称: | CADMIUM ION, MATRIX M2-1 | | 著者 | Tanner, S.J, Ariza, A, Richard, C.A, Wu, W, Trincao, J, Hiscox, J.A, Carroll, M.W, Silman, N.J, Eleouet, J.F, Edwards, T.A, Barr, J.N. | | 登録日 | 2013-08-22 | | 公開日 | 2014-01-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Crystal Structure of the Essential Transcription Antiterminator M2-1 Protein of Human Respiratory Syncytial Virus and Implications of its Phosphorylation.
Proc.Natl.Acad.Sci.USA, 111, 2014
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1TDE
 | | CRYSTAL STRUCTURE OF ESCHERICHIA COLI THIOREDOXIN REDUCTASE REFINED AT 2 ANGSTROM RESOLUTION: IMPLICATIONS FOR A LARGE CONFORMATIONAL CHANGE DURING CATALYSIS | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, THIOREDOXIN REDUCTASE | | 著者 | Waksman, G, Krishna, T.S.R, Williams Junior, C.H, Kuriyan, J. | | 登録日 | 1994-01-14 | | 公開日 | 1994-11-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of Escherichia coli thioredoxin reductase refined at 2 A resolution. Implications for a large conformational change during catalysis.
J.Mol.Biol., 236, 1994
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1TGT
 | | ON THE DISORDERED ACTIVATION DOMAIN IN TRYPSINOGEN. CHEMICAL LABELLING AND LOW-TEMPERATURE CRYSTALLOGRAPHY | | 分子名称: | CALCIUM ION, METHANOL, TRYPSINOGEN | | 著者 | Walter, J, Steigemann, W, Singh, T.P, Bartunik, H, Bode, W, Huber, R. | | 登録日 | 1981-10-26 | | 公開日 | 1982-03-04 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography
Acta Crystallogr.,Sect.B, 38, 1982
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4KCG
 | | Human dCK C4S-S74E mutant in complex with UDP and the DI-39 inhibitor | | 分子名称: | Deoxycytidine kinase, N-{2-[5-(4-{[(4,6-diaminopyrimidin-2-yl)sulfanyl]methyl}-5-propyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]ethyl}methanesulfonamide, URIDINE-5'-DIPHOSPHATE | | 著者 | Nomme, J, Lavie, A. | | 登録日 | 2013-04-24 | | 公開日 | 2014-03-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication.
J.Exp.Med., 211, 2014
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8EVP
 | | Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), Structure I | | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | | 著者 | Zhao, Y, Rai, J, Li, H. | | 登録日 | 2022-10-20 | | 公開日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (2.38 Å) | | 主引用文献 | Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
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8EUB
 | | Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure I | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S0-A, ... | | 著者 | Zhao, Y, Rai, J, Li, H. | | 登録日 | 2022-10-18 | | 公開日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (2.52 Å) | | 主引用文献 | Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
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8EVQ
 | | Hypopseudouridylated Ribosome bound with TSV IRES, eEF2, GDP, and sordarin, Structure I | | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | | 著者 | Zhao, Y, Rai, J, Li, H. | | 登録日 | 2022-10-20 | | 公開日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | | 主引用文献 | Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
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4Y7N
 | | The Structure Insight into 5-Carboxycytosine Recognition by RNA Polymerase II during Transcription Elongation. | | 分子名称: | DNA (29-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Wang, L, Chong, J, Wang, D. | | 登録日 | 2015-02-15 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.
Nature, 523, 2015
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8EVR
 | | Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2, GDP, and sordarin, Structure II | | 分子名称: | (1S,3S,3aR,4S,4aR,7R,7aR,8aS)-8a-{[(6-deoxy-4-O-methyl-alpha-D-altropyranosyl)oxy]methyl}-4-formyl-7-methyl-3-(propan-2-yl)decahydro-1,4-methano-s-indacene-3a(1H)-carboxylate, 18S rRNA, 25S rRNA, ... | | 著者 | Zhao, Y, Rai, J, Li, H. | | 登録日 | 2022-10-20 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-11-01 | | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | | 主引用文献 | Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
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4C3B
 | | HRSV M2-1, P21 crystal form | | 分子名称: | MATRIX PROTEIN 2-1, ZINC ION | | 著者 | Tanner, S.J, Ariza, A, Richard, C.A, Wu, W, Trincao, J, Hiscox, J.A, Carroll, M.W, Silman, N.J, Eleouet, J.F, Edwards, T.A, Barr, J.N. | | 登録日 | 2013-08-22 | | 公開日 | 2014-01-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Crystal Structure of the Essential Transcription Antiterminator M2-1 Protein of Human Respiratory Syncytial Virus and Implications of its Phosphorylation.
Proc.Natl.Acad.Sci.USA, 111, 2014
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8EO5
 | | Crystal structure of the class A beta-lactamase precursor LRA-5 from an Alaskan soil metagenome at 1.8 Angstrom resolution | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, LRA-5 | | 著者 | Power, P, D'Amico Gonzalez, G, Centron, D, Gutkind, G, Handelsman, J, Klinke, S. | | 登録日 | 2022-10-02 | | 公開日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Playing beta-Lactamase Evolution: Metagenomic Class A beta-Lactamase LRA-5 is an Inactive Enzyme Capable of Rendering an Active beta-Lactamase by Introduction of Y69Q and V166E Substitutions
to be published
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4YAS
 | | HYDROXYNITRILE LYASE COMPLEXED WITH CHLORALHYDRATE | | 分子名称: | PROTEIN (HYDROXYNITRILE LYASE), SULFATE ION, TRI-CHLORO-ACETALDEHYDE | | 著者 | Zuegg, J, Wagner, U.G, Gugganig, M, Kratky, C. | | 登録日 | 1999-03-15 | | 公開日 | 1999-10-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three-dimensional structures of enzyme-substrate complexes of the hydroxynitrile lyase from Hevea brasiliensis.
Protein Sci., 8, 1999
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4YBV
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