1HAI
THE ISOMORPHOUS STRUCTURES OF PRETHROMBIN2, HIRUGEN-AND PPACK-THROMBIN: CHANGES ACCOMPANYING ACTIVATION AND EXOSITE BINDING TO THROMBIN
Summary for 1HAI
Entry DOI | 10.2210/pdb1hai/pdb |
Related PRD ID | PRD_000020 |
Descriptor | ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... (5 entities in total) |
Functional Keywords | serine proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 34551.95 |
Authors | Tulinsky, A.,Vijayalakshmi, J. (deposition date: 1994-06-27, release date: 1994-12-20, Last modification date: 2020-07-29) |
Primary citation | Vijayalakshmi, J.,Padmanabhan, K.P.,Mann, K.G.,Tulinsky, A. The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin. Protein Sci., 3:2254-2271, 1994 Cited by PubMed: 7756983PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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