7XVI
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7XVK
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2FQI
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![BU of 2fqi by Molmil](/molmil-images/mine/2fqi) | dual binding modes of a novel series of DHODH inhibitors | 分子名称: | 2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID, ACETATE ION, Dihydroorotate dehydrogenase, ... | 著者 | Baumgartner, R, Leban, J. | 登録日 | 2006-01-18 | 公開日 | 2007-01-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Dual binding mode of a novel series of DHODH inhibitors. J.Med.Chem., 49, 2006
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7XW5
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![BU of 7xw5 by Molmil](/molmil-images/mine/7xw5) | TSHR-thyroid stimulating hormone-Gs-ML109 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, Glycoprotein hormones alpha chain, ... | 著者 | Duan, J, Xu, P, Luan, X, Ji, Y, Yuan, Q, He, X, Ye, J, Cheng, X, Jiang, H, Zhang, S, Jiang, Y, Xu, H.E. | 登録日 | 2022-05-26 | 公開日 | 2022-08-24 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | Hormone- and antibody-mediated activation of the thyrotropin receptor. Nature, 609, 2022
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3UJS
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![BU of 3ujs by Molmil](/molmil-images/mine/3ujs) | Asymmetric complex of human neuron specific enolase-6-PGA/PEP | 分子名称: | (2R)-2-(phosphonooxy)propanoic acid, (2R)-3-oxo-2-(phosphonooxy)propanoic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L. | 登録日 | 2011-11-08 | 公開日 | 2012-08-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity. J.Inorg.Biochem., 111, 2012
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8RUF
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![BU of 8ruf by Molmil](/molmil-images/mine/8ruf) | Crystal structure of Rhizobium etli L-asparaginase ReAV D187A mutant | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | 著者 | Pokrywka, K, Grzechowiak, M, Sliwiak, J, Worsztynowicz, P, Loch, J.I, Ruszkowski, M, Gilski, M, Jaskolski, M. | 登録日 | 2024-01-30 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Probing the active site of Class 3 L-asparaginase by mutagenesis. I. Tinkering with the zinc coordination site of ReAV. Front Chem, 12, 2024
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8RUD
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![BU of 8rud by Molmil](/molmil-images/mine/8rud) | Crystal structure of Rhizobium etli L-asparaginase ReAV K138A mutant | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Pokrywka, K, Grzechowiak, M, Sliwiak, J, Worsztynowicz, P, Loch, J.I, Ruszkowski, M, Gilski, M, Jaskolski, M. | 登録日 | 2024-01-30 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Probing the active site of Class 3 L-asparaginase by mutagenesis. I. Tinkering with the zinc coordination site of ReAV. Front Chem, 12, 2024
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8RUG
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![BU of 8rug by Molmil](/molmil-images/mine/8rug) | Crystal structure of Rhizobium etli L-asparaginase ReAV C189A mutant | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Pokrywka, K, Grzechowiak, M, Sliwiak, J, Worsztynowicz, P, Loch, J.I, Ruszkowski, M, Gilski, M, Jaskolski, M. | 登録日 | 2024-01-30 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Probing the active site of Class 3 L-asparaginase by mutagenesis. I. Tinkering with the zinc coordination site of ReAV. Front Chem, 12, 2024
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8RUE
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![BU of 8rue by Molmil](/molmil-images/mine/8rue) | Crystal structure of Rhizobium etli L-asparaginase ReAV H139A mutant | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | 著者 | Pokrywka, K, Grzechowiak, M, Sliwiak, J, Worsztynowicz, P, Loch, J.I, Ruszkowski, M, Gilski, M, Jaskolski, M. | 登録日 | 2024-01-30 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Probing the active site of Class 3 L-asparaginase by mutagenesis. I. Tinkering with the zinc coordination site of ReAV. Front Chem, 12, 2024
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8RUA
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![BU of 8rua by Molmil](/molmil-images/mine/8rua) | Crystal structure of Rhizobium etli L-asparaginase ReAV C135A mutant | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | 著者 | Pokrywka, K, Grzechowiak, M, Sliwiak, J, Worsztynowicz, P, Loch, J.I, Ruszkowski, M, Gilski, M, Jaskolski, M. | 登録日 | 2024-01-30 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Probing the active site of Class 3 L-asparaginase by mutagenesis. I. Tinkering with the zinc coordination site of ReAV. Front Chem, 12, 2024
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2G98
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![BU of 2g98 by Molmil](/molmil-images/mine/2g98) | human gamma-D-crystallin | 分子名称: | Gamma crystallin D | 著者 | Kmoch, S, Brynda, J, Awsav, B, Bezouska, K, Novak, P, Rezacova, P. | 登録日 | 2006-03-06 | 公開日 | 2006-05-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Link between a novel human gamma-D-crystallin allele and a unique cataract phenotype explained by protein crystallography. Hum.Mol.Genet., 12, 2000
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3UJE
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![BU of 3uje by Molmil](/molmil-images/mine/3uje) | Asymmetric complex of human neuron specific enolase-3-PGA/PEP | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-PHOSPHOGLYCERIC ACID, Gamma-enolase, ... | 著者 | Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L. | 登録日 | 2011-11-07 | 公開日 | 2012-08-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity. J.Inorg.Biochem., 111, 2012
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7XW6
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![BU of 7xw6 by Molmil](/molmil-images/mine/7xw6) | TSHR-Gs-M22 antibody-ML109 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Duan, J, Xu, P, Luan, X, Ji, Y, Yuan, Q, He, X, Ye, J, Cheng, X, Jiang, H, Zhang, S, Jiang, Y, Xu, H.E. | 登録日 | 2022-05-26 | 公開日 | 2022-08-17 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | 主引用文献 | Hormone- and antibody-mediated activation of the thyrotropin receptor. Nature, 609, 2022
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3UCC
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![BU of 3ucc by Molmil](/molmil-images/mine/3ucc) | Asymmetric complex of human neuron specific enolase-1-PGA/PEP | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-PHOSPHOGLYCERIC ACID, Gamma-enolase, ... | 著者 | Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L. | 登録日 | 2011-10-26 | 公開日 | 2012-08-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity. J.Inorg.Biochem., 111, 2012
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8RW3
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![BU of 8rw3 by Molmil](/molmil-images/mine/8rw3) | Crystal Structure of Agd31B, alpha-transglucosylase, complexed with a non-covalent 1,2- Cyclophellitol aziridine | 分子名称: | (1~{S},2~{R},3~{R},4~{R},6~{S})-4-(hydroxymethyl)-7-azabicyclo[4.1.0]heptane-2,3-diol, 1,2-ETHANEDIOL, OXALATE ION, ... | 著者 | Moran, E, Davies, G, Ofamn, T, Heming, J, Nin-Hill, A, Kullmer, F, Steneker, R, Klein, A, Bennett, M, Ruijgrok, G, Kok, K, Aerts, J, Van der Marel, G, Rovira, C, Artola, M, Codee, J, Overkleeft, H. | 登録日 | 2024-02-02 | 公開日 | 2024-05-15 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Conformational and Electronic Variations in 1,2- and 1,5a-Cyclophellitols and their Impact on Retaining alpha-Glucosidase Inhibition. Chemistry, 30, 2024
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5D1Y
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![BU of 5d1y by Molmil](/molmil-images/mine/5d1y) | Low resolution crystal structure of human ribonucleotide reductase alpha6 hexamer in complex with dATP | 分子名称: | Ribonucleoside-diphosphate reductase large subunit | 著者 | Ando, N, Li, H, Brignole, E.J, Thompson, S, McLaughlin, M.I, Page, J, Asturias, F, Stubbe, J, Drennan, C.L. | 登録日 | 2015-08-04 | 公開日 | 2016-01-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (9.005 Å) | 主引用文献 | Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer. Biochemistry, 55, 2016
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3UJF
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![BU of 3ujf by Molmil](/molmil-images/mine/3ujf) | Asymmetric complex of human neuron specific enolase-4-PGA/PEP | 分子名称: | 2-PHOSPHOGLYCERIC ACID, Gamma-enolase, MAGNESIUM ION, ... | 著者 | Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L. | 登録日 | 2011-11-07 | 公開日 | 2012-08-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity. J.Inorg.Biochem., 111, 2012
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8RZ6
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![BU of 8rz6 by Molmil](/molmil-images/mine/8rz6) | SeMet derivative structure of the condensation domain TomBC from the Tomaymycin non-ribosomal peptide synthetase | 分子名称: | FORMIC ACID, GLYCEROL, POTASSIUM ION, ... | 著者 | Karanth, M, Schmelz, S, Kirkpatrick, J, Krausze, J, Scrima, A, Carlomagno, T. | 登録日 | 2024-02-12 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain. Sci Adv, 10, 2024
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2G3R
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![BU of 2g3r by Molmil](/molmil-images/mine/2g3r) | Crystal Structure of 53BP1 tandem tudor domains at 1.2 A resolution | 分子名称: | SULFATE ION, Tumor suppressor p53-binding protein 1 | 著者 | Lee, J, Botuyan, M.V, Thompson, J.R, Mer, G. | 登録日 | 2006-02-20 | 公開日 | 2007-01-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair. Cell(Cambridge,Mass.), 127, 2006
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3UJR
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![BU of 3ujr by Molmil](/molmil-images/mine/3ujr) | Asymmetric complex of human neuron specific enolase-5-PGA/PEP | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-PHOSPHOGLYCERIC ACID, Gamma-enolase, ... | 著者 | Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L. | 登録日 | 2011-11-08 | 公開日 | 2012-08-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity. J.Inorg.Biochem., 111, 2012
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7YGV
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![BU of 7ygv by Molmil](/molmil-images/mine/7ygv) | Crystal structure of the Ca2+-bound EFhd1/Swiprosin-2 | 分子名称: | CALCIUM ION, EF-hand domain-containing protein D1, GLYCEROL, ... | 著者 | Mun, S.A, Park, J, Kang, J.Y, Park, T, Jin, M, Ynag, J, Eom, S.H. | 登録日 | 2022-07-12 | 公開日 | 2023-03-15 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2. Iucrj, 10, 2023
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5DR7
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2G2K
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![BU of 2g2k by Molmil](/molmil-images/mine/2g2k) | NMR structure of an N-terminal fragment of the eukaryotic initiation factor 5 (eIF5) | 分子名称: | Eukaryotic translation initiation factor 5 | 著者 | Conte, M.R, Kelly, G, Babon, J, Sanfelice, D, Smerdon, S.J, Proud, C.G. | 登録日 | 2006-02-16 | 公開日 | 2006-06-13 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the eukaryotic initiation factor (eIF) 5 reveals a fold common to several translation factors Biochemistry, 45, 2006
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5E7Q
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![BU of 5e7q by Molmil](/molmil-images/mine/5e7q) | Acyl-CoA synthetase PtmA2 from Streptomyces platensis | 分子名称: | GLYCEROL, SULFATE ION, acyl-CoA synthetase | 著者 | Osipiuk, J, Cuff, M.E, Hatzos-Skintges, C, Endres, M, Babnigg, G, Rudolf, J, Ma, M, Chang, C.Y, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2015-10-12 | 公開日 | 2015-10-21 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme. Nat. Chem. Biol., 14, 2018
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8YIE
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![BU of 8yie by Molmil](/molmil-images/mine/8yie) | Crystal structure of GH13_30 alpha-glucosidase CmmB in complex with acarbose | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Alpha-glucosidase | 著者 | Saburi, W, Tagami, T, Yu, J, Ose, T, Yao, M, Mori, H. | 登録日 | 2024-02-29 | 公開日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Molecular mechanism for the substrate specificity of Arthrobacter globiformis M6 alpha-glucosidase CmmB, belonging to glycoside hydrolase family 13 subfamily 30 Food Biosci, 61, 2024
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