5E7Q

Acyl-CoA synthetase PtmA2 from Streptomyces platensis

Summary for 5E7Q

• Entry DOI: 10.2210/pdb5e7q/pdb
• Descriptor: acyl-CoA synthetase, SULFATE ION, GLYCEROL, ... (4 entities in total)
• Functional Keywords: acyl-coa synthetase, ptma2, structural genomics, apc109894, midwest center for structural genomics, mcsg, enzyme discovery for natural product biosynthesis, natpro, psi-biology, transferase
• Biological source: Streptomyces platensis subsp. rosaceus
• Total number of polymer chains: 2
• Total formula weight: 116718.67

Authors

Osipiuk, J.,Cuff, M.E.,Hatzos-Skintges, C.,Endres, M.,Babnigg, G.,Rudolf, J.,Ma, M.,Chang, C.Y.,Shen, B.,Phillips Jr., G.N.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG),Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2015-10-12, release date: 2015-10-21, Last modification date: 2019-12-25)

• Primary citation: Wang, N.,Rudolf, J.D.,Dong, L.B.,Osipiuk, J.,Hatzos-Skintges, C.,Endres, M.,Chang, C.Y.,Babnigg, G.,Joachimiak, A.,Phillips, G.N.,Shen, B.; Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme.; Nat. Chem. Biol., 14:730-737, 2018; PubMed: 29867143; DOI: 10.1038/s41589-018-0061-0

Experimental method

X-RAY DIFFRACTION (2.23 Å)