5K7O
 
 | | MicroED structure of lysozyme at 1.8 A resolution | | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | | 登録日 | 2016-05-26 | | 公開日 | 2017-04-05 | | 最終更新日 | 2018-08-22 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.8 Å) | | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
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1W97
 | | cyto-EpsL: the cytoplasmic domain of EpsL, an inner membrane component of the type II secretion system of Vibrio cholerae | | 分子名称: | TYPE II SECRETION SYSTEM PROTEIN L | | 著者 | Abendroth, J, Bagdasarian, M, Sansdkvist, M, Hol, W.G.J. | | 登録日 | 2004-10-06 | | 公開日 | 2004-11-30 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The Structure of the Cytoplasmic Domain of Epsl, an Inner Membrane Component of the Type II Secretion System of Vibrio Cholerae: An Unusual Member of the Actin-Like ATPase Superfamily
J.Mol.Biol., 344, 2004
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1VZE
 | | L. CASEI THYMIDYLATE SYNTHASE MUTANT E60Q TERNARY COMPLEX WITH DUMP AND CB3717 | | 分子名称: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | | 著者 | Birdsall, D.L, Finer-Moore, J, Stroud, R.M. | | 登録日 | 1996-09-18 | | 公開日 | 1997-03-12 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The separate effects of E60Q in Lactobacillus casei thymidylate synthase delineate between mechanisms for formation of intermediates in catalysis.
Protein Eng., 11, 1998
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1VZD
 | | L. CASEI THYMIDYLATE SYNTHASE MUTANT E60Q TERNARY COMPLEX WITH FDUMP AND CB3717 | | 分子名称: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | | 著者 | Birdsall, D.L, Finer-Moore, J, Stroud, R.M. | | 登録日 | 1996-09-18 | | 公開日 | 1997-03-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The separate effects of E60Q in Lactobacillus casei thymidylate synthase delineate between mechanisms for formation of intermediates in catalysis.
Protein Eng., 11, 1998
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1VZC
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1VZA
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1VPC
 | | C-TERMINAL DOMAIN (52-96) OF THE HIV-1 REGULATORY PROTEIN VPR, NMR, 1 STRUCTURE | | 分子名称: | VPR PROTEIN | | 著者 | Schueler, W, De Rocquigny, H, Baudat, Y, Sire, J, Roques, B.P. | | 登録日 | 1998-02-20 | | 公開日 | 1999-03-23 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of the (52-96) C-terminal domain of the HIV-1 regulatory protein Vpr: molecular insights into its biological functions.
J.Mol.Biol., 285, 1999
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4FMK
 | | Crystal structure of mouse nectin-2 extracellular fragment D1-D2 | | 分子名称: | CADMIUM ION, Poliovirus receptor-related protein 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Harrison, O.J, Brasch, J, Shapiro, L. | | 登録日 | 2012-06-17 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Nectin ectodomain structures reveal a canonical adhesive interface.
Nat.Struct.Mol.Biol., 19, 2012
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1W50
 | | Apo Structure of BACE (Beta Secretase) | | 分子名称: | BETA-SECRETASE 1, IODIDE ION | | 著者 | Patel, S, Vuillard, L, Cleasby, A, Murray, C.W, Yon, J. | | 登録日 | 2004-08-04 | | 公開日 | 2004-09-23 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Apo and Inhibitor Complex Structures of Bace (Beta-Secretase)
J.Mol.Biol., 343, 2004
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5K7N
 | | MicroED structure of tau VQIVYK peptide at 1.1 A resolution | | 分子名称: | VQIVYK | | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | | 登録日 | 2016-05-26 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.1 Å) | | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
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5K7S
 | | MicroED structure of proteinase K at 1.6 A resolution | | 分子名称: | CALCIUM ION, Proteinase K | | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | | 登録日 | 2016-05-26 | | 公開日 | 2017-04-05 | | 最終更新日 | 2018-08-22 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.6 Å) | | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
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4FPR
 | | Structure of a fungal protein | | 分子名称: | Avirulence Effector AvrLm4-7 | | 著者 | Blondeau, K, Blaise, F, Graille, M, Linglin, J, Ollivier, B, Labarde, A, Doizy, A, Daverdin, G, Balesdent, M.H, Rouxel, T, van Tilbeurgh, H, Fudal, I. | | 登録日 | 2012-06-22 | | 公開日 | 2013-12-11 | | 最終更新日 | 2022-08-03 | | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | | 主引用文献 | Crystal structure of the effector AvrLm4-7 of Leptosphaeria maculans reveals insights into its translocation into plant cells and recognition by resistance proteins.
Plant J., 83, 2015
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4W2E
 | | Crystal structure of Elongation Factor 4 (EF4/LepA) bound to the Thermus thermophilus 70S ribosome | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Gagnon, M.G, Lin, J, Steitz, T.A. | | 登録日 | 2014-06-04 | | 公開日 | 2014-10-01 | | 最終更新日 | 2023-07-26 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome.
Science, 345, 2014
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5KE4
 | | Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 6 nicotinic acetylcholine receptor in complex with 2-((5-(3,7-Diazabicyclo[3.3.1]nonan-3-yl)pyridin-3-yl)oxy)- N,N-dimethylethanamine (BPC) | | 分子名称: | 2-((5-(3,7-Diazabicyclo[3.3.1]nonan-3-yl)pyridin-3-yl)oxy)-N,N-dimethylethanamine, Soluble acetylcholine receptor | | 著者 | Bobango, J, Wu, J, Talley, I.T, Ralston, R, Sankaran, B, Talley, T.T. | | 登録日 | 2016-06-09 | | 公開日 | 2016-07-06 | | 実験手法 | X-RAY DIFFRACTION (2.554 Å) | | 主引用文献 | Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 6 nicotinic acetylcholine receptor in complex with 2-((5-(3,7-Diazabicyclo[3.3.1]nonan-3-yl)pyridin-3-yl)oxy)-
N,N-dimethylethanamine (BPC)
To Be Published
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6KI3
 | | The crystal structure of AsfvAP:dF commplex | | 分子名称: | DNA (5'-D(*CP*CP*TP*CP*GP*TP*CP*GP*GP*GP*GP*AP*CP*GP*CP*TP*G)-3'), DNA (5'-D(*GP*CP*AP*GP*CP*GP*TP*CP*C)-3'), DNA (5'-D(P*(3DR)P*CP*GP*AP*CP*GP*AP*G)-3'), ... | | 著者 | Chen, Y, Gan, J. | | 登録日 | 2019-07-17 | | 公開日 | 2020-05-27 | | 実験手法 | X-RAY DIFFRACTION (2.354 Å) | | 主引用文献 | A unique DNA-binding mode of African swine fever virus AP endonuclease.
Cell Discov, 6, 2020
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4W5S
 | | Tankyrase in complex with compound | | 分子名称: | 8-(hydroxymethyl)-2-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]quinazolin-4(3H)-one, GLYCEROL, Tankyrase-1, ... | | 著者 | Johannes, J, Kazmirski, S.L, Boriack-Sjodin, P.A, Howard, T. | | 登録日 | 2014-08-18 | | 公開日 | 2015-05-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Pyrimidinone nicotinamide mimetics as selective tankyrase and wnt pathway inhibitors suitable for in vivo pharmacology.
Acs Med.Chem.Lett., 6, 2015
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4FFG
 | | Crystal Structure of Levan Fructotransferase from Arthrobacter ureafaciens in complex with DFA-IV | | 分子名称: | (1R,4R,5S,6S,7R,10R,11S,12S)-1,7-bis(hydroxymethyl)-2,8,13,14-tetraoxatricyclo[8.2.1.1~4,7~]tetradecane-5,6,11,12-tetrol, Levan fructotransferase, beta-D-fructofuranose-(2-6)-beta-D-fructofuranose | | 著者 | Park, J, Rhee, S. | | 登録日 | 2012-06-01 | | 公開日 | 2012-07-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and functional basis for substrate specificity and catalysis of levan fructotransferase.
J.Biol.Chem., 287, 2012
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1W1U
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1W51
 | | BACE (Beta Secretase) in complex with a nanomolar non-peptidic inhibitor | | 分子名称: | 3-[({(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}AMINO)(HYDROXY)METHYL]-N,N-DIPROPYLBENZAMIDE, BETA-SECRETASE 1, IODIDE ION | | 著者 | Patel, S, Vuillard, L, Cleasby, A, Murray, C.W, Yon, J. | | 登録日 | 2004-08-04 | | 公開日 | 2004-09-23 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Apo and Inhibitor Complex Structures of Bace (Beta-Secretase)
J.Mol.Biol., 343, 2004
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1W3W
 | | The 2.1 Angstroem resolution structure of annexin A8 | | 分子名称: | ANNEXIN A8, CALCIUM ION | | 著者 | Rety, S, Sopkova-De Oliveira Santos, J, Renouard, M, Lewit-Bentley, A. | | 登録日 | 2004-07-20 | | 公開日 | 2005-01-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | The Crystal Structure of Annexin A8 is Similar to that of Annexin A3
J.Mol.Biol., 345, 2005
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4FJV
 | | Crystal Structure of Human Otubain2 and Ubiquitin Complex | | 分子名称: | ETHANAMINE, GLYCEROL, Polyubiquitin-C, ... | | 著者 | Altun, M, Walter, T.S, Kramer, H.B, Iphofer, A, David, Y, Komsany, A, Ternette, N, Nicholson, B, Navon, A, Stuart, D.I, Ren, J, Kessler, B.M. | | 登録日 | 2012-06-12 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.047 Å) | | 主引用文献 | The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages.
Plos One, 10, 2015
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4FOM
 | | Crystal structure of human nectin-3 full ectodomain (D1-D3) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Poliovirus receptor-related protein 3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Harrison, O.J, Jin, X, Brasch, J, Shapiro, L. | | 登録日 | 2012-06-20 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.93 Å) | | 主引用文献 | Nectin ectodomain structures reveal a canonical adhesive interface.
Nat.Struct.Mol.Biol., 19, 2012
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4FQP
 | | Crystal structure of human Nectin-like 5 full ectodomain (D1-D3) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Poliovirus receptor, ... | | 著者 | Harrison, O.J, Jin, X, Brasch, J, Shapiro, L. | | 登録日 | 2012-06-25 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Nectin ectodomain structures reveal a canonical adhesive interface.
Nat.Struct.Mol.Biol., 19, 2012
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4FFF
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4V7E
 | | Model of the small subunit RNA based on a 5.5 A cryo-EM map of Triticum aestivum translating 80S ribosome | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S10E, ... | | 著者 | Barrio-Garcia, C, Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R. | | 登録日 | 2013-11-22 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-02-01 | | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | | 主引用文献 | Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion.
Nature, 506, 2014
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