3FMP
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![BU of 3fmp by Molmil](/molmil-images/mine/3fmp) | Crystal structure of the nucleoporin Nup214 in complex with the DEAD-box helicase Ddx19 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DDX19B, Nuclear pore complex protein Nup214 | 著者 | Napetschnig, J, Debler, E.W, Blobel, G, Hoelz, A. | 登録日 | 2008-12-22 | 公開日 | 2009-05-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | Structural and functional analysis of the interaction between the nucleoporin Nup214 and the DEAD-box helicase Ddx19. Proc.Natl.Acad.Sci.USA, 106, 2009
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6BZ2
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![BU of 6bz2 by Molmil](/molmil-images/mine/6bz2) | Crystal structure of wild-type HIV-1 protease with a novel HIV-1 inhibitor GRL-14213A of 6-5-5-ring fused crown-like tetrahydropyranofuran as the P2-ligand, a cyclopropylaminobenzothiazole as the P2'-ligand and 3,5-difluorophenylmethyl as the P1-ligand | 分子名称: | (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]carbamate, ACETATE ION, CHLORIDE ION, ... | 著者 | Wang, Y.-F, Agniswamy, J, Weber, I.T. | 登録日 | 2017-12-22 | 公開日 | 2018-02-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Design of Highly Potent, Dual-Acting and Central-Nervous-System-Penetrating HIV-1 Protease Inhibitors with Excellent Potency against Multidrug-Resistant HIV-1 Variants. ChemMedChem, 13, 2018
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3FNJ
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![BU of 3fnj by Molmil](/molmil-images/mine/3fnj) | Crystal structure of the full-length lp_1913 protein from Lactobacillus plantarum, Northeast Structural Genomics Consortium Target LpR140 | 分子名称: | protein lp_1913 | 著者 | Seetharaman, J, Chen, Y, Forouhar, F, Sahdev, S, Janjua, H, Xiao, R, Ciccosanti, C, Foote, E.L, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-12-25 | 公開日 | 2009-01-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of the full-length lp_1913 protein from Lactobacillus plantarum, Northeast Structural Genomics Consortium Target LpR140 To be Published
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6GAY
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3FEQ
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![BU of 3feq by Molmil](/molmil-images/mine/3feq) | Crystal structure of uncharacterized protein eah89906 | 分子名称: | PUTATIVE AMIDOHYDROLASE, ZINC ION | 著者 | Patskovsky, Y, Bonanno, J, Romero, R, Freeman, J, Lau, C, Smith, D, Bain, K, Wasserman, S.R, Raushel, F, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2008-11-30 | 公開日 | 2008-12-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Functional identification and structure determination of two novel prolidases from cog1228 in the amidohydrolase superfamily . Biochemistry, 49, 2010
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6BW6
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![BU of 6bw6 by Molmil](/molmil-images/mine/6bw6) | Human GPT (DPAGT1) H129 variant in complex with tunicamycin | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Tunicamycin, UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase | 著者 | Yoo, J, Kuk, A.C.Y, Mashalidis, E.H, Lee, S.-Y. | 登録日 | 2017-12-14 | 公開日 | 2018-02-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation. Nat. Struct. Mol. Biol., 25, 2018
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6GB3
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3FH6
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![BU of 3fh6 by Molmil](/molmil-images/mine/3fh6) | Crystal structure of the resting state maltose transporter from E. coli | 分子名称: | Maltose transport system permease protein malF, Maltose transport system permease protein malG, Maltose/maltodextrin import ATP-binding protein malK | 著者 | Khare, D, Oldham, M.L, Orelle, C, Davidson, A.L, Chen, J. | 登録日 | 2008-12-08 | 公開日 | 2009-03-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | 主引用文献 | Alternating access in maltose transporter mediated by rigid-body rotations. Mol.Cell, 33, 2009
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3F4D
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![BU of 3f4d by Molmil](/molmil-images/mine/3f4d) | Crystal structure of organophosphorus hydrolase from Geobacillus stearothermophilus strain 10 | 分子名称: | COBALT (II) ION, Organophosphorus hydrolase | 著者 | Hawwa, R, Aikens, J, Turner, R.J, Santarsiero, B, Mesecar, A. | 登録日 | 2008-10-31 | 公開日 | 2009-08-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Structural basis for thermostability revealed through the identification and characterization of a highly thermostable phosphotriesterase-like lactonase from Geobacillus stearothermophilus. Arch.Biochem.Biophys., 488, 2009
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6BXB
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![BU of 6bxb by Molmil](/molmil-images/mine/6bxb) | Crystal structure of an extended b3 integrin P33 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Chimera protein of Integrin beta-3 and Integrin alpha-L, ... | 著者 | Zhou, D, Zhu, J. | 登録日 | 2017-12-18 | 公開日 | 2018-08-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structure of an extended beta3integrin. Blood, 132, 2018
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3F6M
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![BU of 3f6m by Molmil](/molmil-images/mine/3f6m) | Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF from Yersinia pestis | 分子名称: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 著者 | Kim, Y, Maltseva, N, Stam, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2008-11-06 | 公開日 | 2008-11-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | 主引用文献 | Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF from Yersinia pestis To be Published
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6BY7
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![BU of 6by7 by Molmil](/molmil-images/mine/6by7) | Folding DNA into a lipid-conjugated nano-barrel for controlled reconstitution of membrane proteins | 分子名称: | DNA (26-MER), DNA (27-MER), DNA (29-MER), ... | 著者 | Dong, Y, Chen, S, Zhang, S, Sodroski, J, Yang, Z, Liu, D, Mao, Y. | 登録日 | 2017-12-20 | 公開日 | 2018-02-28 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | 主引用文献 | Folding DNA into a Lipid-Conjugated Nanobarrel for Controlled Reconstitution of Membrane Proteins. Angew. Chem. Int. Ed. Engl., 57, 2018
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3FJD
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3FJJ
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6C5R
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![BU of 6c5r by Molmil](/molmil-images/mine/6c5r) | Crystal structure of the soluble domain of the mitochondrial calcium uniporter | 分子名称: | calcium uniporter | 著者 | Fan, C, Fan, M, Fastman, N, Zhang, J, Feng, L. | 登録日 | 2018-01-16 | 公開日 | 2018-07-11 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.09608316 Å) | 主引用文献 | X-ray and cryo-EM structures of the mitochondrial calcium uniporter. Nature, 559, 2018
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3FLE
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![BU of 3fle by Molmil](/molmil-images/mine/3fle) | SE_1780 protein of unknown function from Staphylococcus epidermidis. | 分子名称: | SE_1780 protein | 著者 | Osipiuk, J, Hatzos, C, Clancy, S, Kim, Y, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2008-12-18 | 公開日 | 2009-01-13 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.009 Å) | 主引用文献 | X-ray crystal structure of SE_1780 protein of unknown function from Staphylococcus epidermidis. To be Published
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6G0D
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6G0F
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![BU of 6g0f by Molmil](/molmil-images/mine/6g0f) | BRD4 (BD1) in complex with docking-derived ligand | 分子名称: | (4~{R})-4-(5-bromanyl-2-fluoranyl-phenyl)-5,6,7-trimethoxy-3,4-dihydro-1~{H}-quinolin-2-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4 | 著者 | Pretzel, J, Humbeck, L. | 登録日 | 2018-03-18 | 公開日 | 2020-01-08 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.618 Å) | 主引用文献 | Discovery of an Unexpected Similarity in Ligand Binding Between BRD4 and PPARgamma Chemrxiv, 2019
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6FNE
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![BU of 6fne by Molmil](/molmil-images/mine/6fne) | Structure of human Brag2 (Sec7-PH domains) with the inhibitor Bragsin bound to the PH domain | 分子名称: | (2~{S})-6-methyl-5-nitro-2-(trifluoromethyl)-2,3-dihydrochromen-4-one, IQ motif and SEC7 domain-containing protein 1, NONAETHYLENE GLYCOL | 著者 | Nawrotek, A, Zeghouf, M, Cherfils, J. | 登録日 | 2018-02-03 | 公開日 | 2019-03-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling. Nat.Chem.Biol., 15, 2019
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6C1Y
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![BU of 6c1y by Molmil](/molmil-images/mine/6c1y) | mbd of human mecp2 in complex with methylated DNA | 分子名称: | 12-mer DNA, Methyl-CpG-binding protein 2, UNKNOWN ATOM OR ION | 著者 | Liu, K, Bian, C, Tempel, W, Wernimont, A.K, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2018-01-05 | 公開日 | 2018-02-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain. Biochim Biophys Acta Gene Regul Mech, 1862, 2019
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3FFO
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![BU of 3ffo by Molmil](/molmil-images/mine/3ffo) | F17b-G lectin domain with bound GlcNAc(beta1-2)man | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose, Adhesin, ... | 著者 | Buts, L, De Boer, A, Olsson, J.D.M, Jonckheere, W, De Kerpel, M, De Genst, E, Guerardel, Y, Willaert, R, Wyns, L, Wuhrer, M, Oscarson, S, De Greve, H, Bouckaert, J. | 登録日 | 2008-12-04 | 公開日 | 2009-12-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Sampling of Glycan Interaction Profiles Reveals Mucosal Receptors for Fimbrial Adhesins of Enterotoxigenic Escherichia coli. Biology (Basel), 2, 2013
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3FGM
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6C3P
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![BU of 6c3p by Molmil](/molmil-images/mine/6c3p) | Cryo-EM structure of human KATP bound to ATP and ADP in propeller form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | 著者 | Lee, K.P.K, Chen, J, MacKinnon, R. | 登録日 | 2018-01-10 | 公開日 | 2018-01-24 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | Molecular structure of human KATP in complex with ATP and ADP. Elife, 6, 2017
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3FH3
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![BU of 3fh3 by Molmil](/molmil-images/mine/3fh3) | Crystal structure of a putative ECF-type sigma factor negative effector from Bacillus anthracis str. Sterne | 分子名称: | NICKEL (II) ION, putative ECF-type sigma factor negative effector | 著者 | Nocek, B, Kim, Y, Joachimiak, G, Du, J, Gornicki, P, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2008-12-08 | 公開日 | 2009-01-06 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | 主引用文献 | Crystal structure of a putative ECF-type sigma factor negative effector from Bacillus anthracis str. Sterne To be Published
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3F4K
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![BU of 3f4k by Molmil](/molmil-images/mine/3f4k) | Crystal structure of a probable methyltransferase from Bacteroides thetaiotaomicron. Northeast Structural Genomics target BtR309. | 分子名称: | Putative methyltransferase | 著者 | Seetharaman, J, Lew, S, Wang, H, Janjua, H, Foote, E.L, Xiao, R, Nair, R, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-10-31 | 公開日 | 2008-11-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of a probable methyltransferase from Bacteroides thetaiotaomicron. Northeast Structural Genomics target BtR309. To be Published
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