8TGH
| VMAT1 dimer with amphetamine and reserpine | Descriptor: | (2S)-1-phenylpropan-2-amine, Chromaffin granule amine transporter, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGL
| VMAT1 dimer with norepinephrine and reserpine | Descriptor: | Chromaffin granule amine transporter, L-NOREPINEPHRINE, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGM
| VMAT1 dimer with reserpine | Descriptor: | VMAT1 dimer with reserpine, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TOB
| Acinetobacter GP16 Type IV pilus | Descriptor: | Fimbrial protein | Authors: | Meng, R, Xing, Z, Zhang, J. | Deposit date: | 2023-08-03 | Release date: | 2024-03-06 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Structural basis of Acinetobacter type IV pili targeting by an RNA virus. Nat Commun, 15, 2024
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8TGI
| VMAT1 dimer with dopamine and reserpine | Descriptor: | Chromaffin granule amine transporter, L-DOPAMINE, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGJ
| VMAT1 dimer in unbound form and with reserpine | Descriptor: | VMAT1 dimer in unbound form and with reserpine, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGK
| VMAT1 dimer with histamine and reserpine | Descriptor: | Chromaffin granule amine transporter, HISTAMINE, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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4WCZ
| Crystal structure of a putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans | Descriptor: | Enoyl-CoA hydratase/isomerase | Authors: | Tkaczuk, K.L, Cooper, D.R, Chapman, H.C, Niedzialkowska, E, Cymborowski, M.T, Hillerich, B.S, Stead, M, Ahmed, M, Hammonds, J, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2014-09-05 | Release date: | 2014-12-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Crystal structure of a putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans to be published
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8TQ9
| Crystal structure of Fab.S19.8 in complex with MHC-I (H2-Dd) | Descriptor: | Beta-2-microglobulin, Fab.S19.8 Heavy Chain, Fab.S19.8 Light Chain, ... | Authors: | Jiang, J, Boyd, L.F, Natarajan, K, Margulies, D.H. | Deposit date: | 2023-08-06 | Release date: | 2024-03-20 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Experimental Structures of Antibody/MHC-I Complexes Reveal Details of Epitopes Overlooked by Computational Prediction. J Immunol., 212, 2024
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4V6O
| Structural characterization of mRNA-tRNA translocation intermediates (class 4a of the six classes) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J. | Deposit date: | 2011-12-07 | Release date: | 2014-07-09 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (14.7 Å) | Cite: | Structural characterization of mRNA-tRNA translocation intermediates. Proc.Natl.Acad.Sci.USA, 109, 2012
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8TWC
| Acinetobacter phage AP205 T=3 VLP | Descriptor: | Coat protein | Authors: | Meng, R, Xing, Z, Zhang, J. | Deposit date: | 2023-08-20 | Release date: | 2024-03-06 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of Acinetobacter type IV pili targeting by an RNA virus. Nat Commun, 15, 2024
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8U8L
| X-ray crystal structure of TEBP-2 MCD3 with ds DNA | Descriptor: | CESIUM ION, DNA (5'-D(*CP*TP*GP*TP*TP*AP*GP*GP*CP*TP*TP*AP*GP*GP*CP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*GP*CP*CP*TP*AP*AP*GP*CP*CP*TP*AP*AP*CP*A)-3'), ... | Authors: | Nandakumar, J, Padmanaban, S. | Deposit date: | 2023-09-18 | Release date: | 2024-04-03 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Caenorhabditis elegans telomere-binding proteins TEBP-1 and TEBP-2 adapt the Myb module to dimerize and bind telomeric DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
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8U8M
| X-ray crystal structure of TEBP-1 MCD2 homodimer | Descriptor: | COBALT (II) ION, Double-strand telomeric DNA-binding proteins 1 | Authors: | Nandakumar, J, Padmanaban, S. | Deposit date: | 2023-09-18 | Release date: | 2024-04-03 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Caenorhabditis elegans telomere-binding proteins TEBP-1 and TEBP-2 adapt the Myb module to dimerize and bind telomeric DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
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2FQN
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2FSP
| NMR SOLUTION STRUCTURE OF BACILLUS SUBTILIS SPO0F PROTEIN, MINIMIZED AVERAGE STRUCTURE | Descriptor: | STAGE 0 SPORULATION PROTEIN F | Authors: | Feher, V.A, Skelton, N.J, Dahlquist, F.W, Cavanagh, J. | Deposit date: | 1997-06-06 | Release date: | 1997-12-10 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | High-resolution NMR structure and backbone dynamics of the Bacillus subtilis response regulator, Spo0F: implications for phosphorylation and molecular recognition. Biochemistry, 36, 1997
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7XB4
| Crystal structure of SARS-Cov-2 main protease D48N mutant in complex with PF07321332 | Descriptor: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, Replicase polyprotein 1a | Authors: | Hu, X.H, Li, J, Zhang, J. | Deposit date: | 2022-03-20 | Release date: | 2023-03-22 | Last modified: | 2024-10-02 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structural Basis for the Inhibition of SARS-CoV-2 M pro D48N Mutant by Shikonin and PF-07321332. Viruses, 16, 2023
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4V0B
| Escherichia coli FtsH hexameric N-domain | Descriptor: | ATP-DEPENDENT ZINC METALLOPROTEASE FTSH, SULFATE ION | Authors: | Serek-Heuberger, J, Martin, J, Lupas, A.N, Hartmann, M.D. | Deposit date: | 2014-09-13 | Release date: | 2015-01-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structure and Evolution of N-Domains in Aaa Metalloproteases. J.Mol.Biol., 427, 2015
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4V06
| Crystal structure of human tryptophan hydroxylase 2 (TPH2), catalytic domain | Descriptor: | FE (III) ION, IMIDAZOLE, TRYPTOPHAN 5-HYDROXYLASE 2 | Authors: | Kopec, J, Oberholzer, A, Fitzpatrick, F, Newman, J, Tallant, C, Kiyani, W, Shrestha, L, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W. | Deposit date: | 2014-09-11 | Release date: | 2014-10-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Crystal Structure of Human Tryptophane Hydroxylase 2 (Tph2), Catalytic Domain To be Published
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4V0Q
| Dengue Virus Full Length NS5 Complexed with SAH | Descriptor: | ACETATE ION, GLYCEROL, NS5 POLYMERASE, ... | Authors: | Zhao, Y, Soh, S, Zheng, J, Phoo, W.W, Swaminathan, K, Cornvik, T.C, Lim, S.P, Shi, P.-Y, Lescar, J, Vasudevan, S.G, Luo, D. | Deposit date: | 2014-09-18 | Release date: | 2015-01-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A Crystal Structure of the Dengue Virus Ns5 Protein Reveals a Novel Inter-Domain Interface Essential for Protein Flexibility and Virus Replication. Plos Pathog., 11, 2015
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2FV7
| Crystal structure of human ribokinase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ribokinase, ... | Authors: | Rabeh, W.M, Tempel, W, Nedyalkova, L, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2006-01-30 | Release date: | 2006-02-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of human ribokinase to be published
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2FZA
| Crystal structure of d(GCGGGAGC): the base-intercalated duplex | Descriptor: | 5'-D(*GP*(CBR)P*GP*GP*GP*AP*GP*C)-3', CALCIUM ION, SODIUM ION | Authors: | Kondo, J, Ciengshin, T, Juan, E.C.M, Mitomi, K, Takenaka, A. | Deposit date: | 2006-02-09 | Release date: | 2007-01-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Crystal structure of d(gcGXGAgc) with X=G: a mutation at X is possible to occur in a base-intercalated duplex for multiplex formation Nucleosides Nucleotides Nucleic Acids, 25, 2006
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2FS1
| solution structure of PSD-1 | Descriptor: | PSD-1 | Authors: | He, Y, Rozak, D.A, Sari, N, Chen, Y, Bryan, P, Orban, J. | Deposit date: | 2006-01-20 | Release date: | 2006-12-05 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure, dynamics, and stability variation in bacterial albumin binding modules: implications for species specificity. Biochemistry, 45, 2006
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4USD
| Human STK10 (LOK) with SB-633825 | Descriptor: | 4-{5-(6-methoxynaphthalen-2-yl)-1-methyl-2-[2-methyl-4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl}pyridine, SERINE/THREONINE-PROTEIN KINASE 10 | Authors: | Elkins, J.M, Salah, E, Szklarz, M, von Delft, F, Canning, P, Raynor, J, Bountra, C, Edwards, A.M, Knapp, S. | Deposit date: | 2014-07-07 | Release date: | 2015-07-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Comprehensive Characterization of the Published Kinase Inhibitor Set. Nat.Biotechnol., 34, 2016
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7XOF
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4WXB
| Crystal Structure of Serine Hydroxymethyltransferase from Streptococcus thermophilus | Descriptor: | CACODYLATE ION, CITRIC ACID, GLYCEROL, ... | Authors: | Hernandez, K, Zelen, I, Petrillo, G, Uson, I, Wandtke, C, Bujons, J, Joglar, J, Parella, T, Clapes, P. | Deposit date: | 2014-11-13 | Release date: | 2015-02-04 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Engineered L-Serine Hydroxymethyltransferase from Streptococcus thermophilus for the Synthesis of alpha , alpha-Dialkyl-alpha-Amino Acids. Angew.Chem.Int.Ed.Engl., 54, 2015
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