5XAU
| Crystal structure of integrin binding fragment of laminin-511 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Takizawa, M, Arimori, T, Kitago, Y, Takagi, J, Sekiguchi, K. | 登録日 | 2017-03-15 | 公開日 | 2017-09-20 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Mechanistic basis for the recognition of laminin-511 by alpha 6 beta 1 integrin. Sci Adv, 3, 2017
|
|
7WOX
| PPARgamma antagonist (MMT-160)- PPARgamma LBD complex | 分子名称: | N-[[5-(3-phenylprop-2-ynoylamino)-2-propoxy-phenyl]methyl]-4-pyrimidin-2-yl-benzamide, Peroxisome proliferator-activated receptor gamma | 著者 | Yoshizawa, M, Aoyama, T, Itoh, T, Miyachi, H. | 登録日 | 2022-01-22 | 公開日 | 2022-04-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Arylalkynyl amide-type peroxisome proliferator-activated receptor gamma (PPAR gamma )-selective antagonists covalently bind to the PPAR gamma ligand binding domain with a unique binding mode. Bioorg.Med.Chem.Lett., 64, 2022
|
|
5ZWI
| Interaction between Vitamin D receptor (VDR) and a ligand having a dienone group | 分子名称: | (2S)-2-[(1R,3aS,4E,7aR)-7a-methyl-4-[2-[(3R,5R)-4-methylidene-3,5-bis(oxidanyl)cyclohexylidene]ethylidene]-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]oct-4,6-diene-3-one, 13-meric peptide from DRIP205 NR2 BOX peptide, Vitamin D3 receptor | 著者 | Yoshizawa, M, Itoh, T, Anami, Y, Kato, A, Yoshimoto, N, Yamamoto, K. | 登録日 | 2018-05-15 | 公開日 | 2018-07-18 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Identification of the Histidine Residue in Vitamin D Receptor That Covalently Binds to Electrophilic Ligands J. Med. Chem., 61, 2018
|
|
5ZWH
| Covalent bond formation between histidine of Vitamin D receptor (VDR) and a full agonist having an ene-ynone group via conjugate addition reaction | 分子名称: | (2S)-2-[(1R,3aS,4E,7aR)-7a-methyl-4-[2-[(3R,5R)-4-methylidene-3,5-bis(oxidanyl)cyclohexylidene]ethylidene]-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]oct-4,6-diene-3-one, (E,2S)-2-[(1R,3aS,4E,7aR)-7a-methyl-4-[2-[(3R,5R)-4-methylidene-3,5-bis(oxidanyl)cyclohexylidene]ethylidene]-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]oct-6-en-4-yn-3-one, 13-meric peptide from DRIP205 NR2 BOX peptide, ... | 著者 | Yoshizawa, M, Itoh, T, Anami, Y, Kato, A, Yoshimoto, N, Yamamoto, K. | 登録日 | 2018-05-15 | 公開日 | 2018-07-18 | 最終更新日 | 2018-08-08 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Identification of the Histidine Residue in Vitamin D Receptor That Covalently Binds to Electrophilic Ligands J. Med. Chem., 61, 2018
|
|
5ZWE
| Covalent bond formation between histidine of Vitamin D receptor (VDR) and a full agonist having a vinyl ketone group via conjugate addition reaction | 分子名称: | (6R)-6-[(1R,3aS,4E,7aR)-7a-methyl-4-[2-[(3R,5R)-4-methylidene-3,5-bis(oxidanyl)cyclohexylidene]ethylidene]-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]hept-1-en-3-one, 13-meric peptide from DRIP205 NR2 BOX peptide, Vitamin D3 receptor | 著者 | Yoshizawa, M, Itoh, T, Anami, Y, Kato, A, Yoshimoto, N, Yamamoto, K. | 登録日 | 2018-05-15 | 公開日 | 2018-07-18 | 最終更新日 | 2018-08-08 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Identification of the Histidine Residue in Vitamin D Receptor That Covalently Binds to Electrophilic Ligands J. Med. Chem., 61, 2018
|
|
5ZWF
| Covalent bond formation between histidine of Vitamin D receptor (VDR) and a full agonist having a enone with a beta methyl group via conjugate addition reaction | 分子名称: | (E,7R)-7-[(1R,3aS,4E,7aR)-7a-methyl-4-[2-[(3R,5R)-4-methylidene-3,5-bis(oxidanyl)cyclohexylidene]ethylidene]-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]oct-2-en-4-one, 13-meric peptide from DRIP205 NR2 BOX peptide, Vitamin D3 receptor | 著者 | Yoshizawa, M, Itoh, T, Anami, Y, Kato, A, Yoshimoto, N, Yamamoto, K. | 登録日 | 2018-05-15 | 公開日 | 2018-07-18 | 最終更新日 | 2018-08-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Identification of the Histidine Residue in Vitamin D Receptor That Covalently Binds to Electrophilic Ligands J. Med. Chem., 61, 2018
|
|
9JBQ
| Structure of the complex between h1F3 Fab and PcrV fragment | 分子名称: | Heavy chain, PcrV, light chain | 著者 | Numata, S, Hara, T, Izawa, M, Okuno, Y, Sato, Y, Yamane, S, Maki, H, Sato, T, Yamano, Y. | 登録日 | 2024-08-27 | 公開日 | 2024-09-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Novel humanized anti-PcrV monoclonal antibody, COT-143, protects mice from lethal Pseudomonas aeruginosa infection via inhibition of toxin translocation by the type III secretion system To Be Published
|
|
7X9U
| Type-II KH motif of human mitochondrial RbfA | 分子名称: | Putative ribosome-binding factor A, mitochondrial | 著者 | Kuwasako, K, Suzuki, S, Furue, M, Takizawa, M, Takahashi, M, Tsuda, K, Nagata, T, Watanabe, S, Tanaka, A, Kobayashi, N, Kigawa, T, Guntert, P, Shirouzu, M, Yokoyama, S, Muto, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2022-03-16 | 公開日 | 2023-01-25 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | 1 H, 13 C, and 15 N resonance assignments and solution structures of the KH domain of human ribosome binding factor A, mtRbfA, involved in mitochondrial ribosome biogenesis. Biomol.Nmr Assign., 16, 2022
|
|
3BUZ
| Crystal structure of ia-bTAD-actin complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Tsuge, H, Nagahama, M, Oda, M, Iwamoto, S, Utsunomiya, H, Marquez, V.E, Katunuma, N, Nishizawa, M, Sakurai, J. | 登録日 | 2008-01-04 | 公開日 | 2008-05-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structural basis of actin recognition and arginine ADP-ribosylation by Clostridium perfringens iota-toxin Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
3C79
| Crystal structure of Aplysia californica AChBP in complex with the neonicotinoid imidacloprid | 分子名称: | (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine, ISOPROPYL ALCOHOL, Soluble acetylcholine receptor | 著者 | Talley, T.T, Harel, M, Hibbs, R.E, Tomizawa, M, Casida, J.E, Taylor, P.W. | 登録日 | 2008-02-06 | 公開日 | 2008-05-20 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore. Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
3C84
| Crystal structure of a complex of AChBP from aplysia californica and the neonicotinoid thiacloprid | 分子名称: | ISOPROPYL ALCOHOL, MAGNESIUM ION, Soluble acetylcholine receptor, ... | 著者 | Talley, T.T, Harel, M, Hibbs, R.E, Tomizawa, M, Casida, J.E, Taylor, P.W. | 登録日 | 2008-02-08 | 公開日 | 2008-05-20 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore. Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
7VH9
| Solution structure of the chimeric peptide of the first SURP domain of Human SF3A1 and the interacting region of SF1. | 分子名称: | Splicing factor 3A subunit 1,Splicing factor 1 | 著者 | Muto, Y, Kuwasako, K, Takizawa, M, Kobayashi, N, Sakamoto, T. | 登録日 | 2021-09-21 | 公開日 | 2022-09-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for the interaction between the first SURP domain of the SF3A1 subunit in U2 snRNP and the human splicing factor SF1. Protein Sci., 31, 2022
|
|