1AF3
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![BU of 1af3 by Molmil](/molmil-images/mine/1af3) | RAT BCL-XL AN APOPTOSIS INHIBITORY PROTEIN | Descriptor: | APOPTOSIS REGULATOR BCL-X | Authors: | Aritomi, M, Kunishima, N, Inohara, N, Ishibashi, Y, Ohta, S, Morikawa, K. | Deposit date: | 1997-03-21 | Release date: | 1997-07-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of rat Bcl-xL. Implications for the function of the Bcl-2 protein family. J.Biol.Chem., 272, 1997
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1CD9
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![BU of 1cd9 by Molmil](/molmil-images/mine/1cd9) | 2:2 COMPLEX OF G-CSF WITH ITS RECEPTOR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (G-CSF RECEPTOR), PROTEIN (GRANULOCYTE COLONY-STIMULATING FACTOR) | Authors: | Aritomi, M, Kunishima, N, Okamoto, T, Kuroki, R, Ota, Y, Morikawa, K. | Deposit date: | 1999-03-08 | Release date: | 2000-03-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Atomic structure of the GCSF-receptor complex showing a new cytokine-receptor recognition scheme. Nature, 401, 1999
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2JNJ
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![BU of 2jnj by Molmil](/molmil-images/mine/2jnj) | Solution structure of the p8 TFIIH subunit | Descriptor: | TFIIH basal transcription factor complex TTD-A subunit | Authors: | Vitorino, M, Atkinson, R.A, Moras, D, Poterszman, A, Kieffer, B, Structural Proteomics in Europe 2 (SPINE-2) | Deposit date: | 2007-01-26 | Release date: | 2007-04-10 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Solution Structure and Self-association Properties of the p8 TFIIH Subunit Responsible for Trichothiodystrophy J.Mol.Biol., 368, 2007
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1PGR
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![BU of 1pgr by Molmil](/molmil-images/mine/1pgr) | 2:2 COMPLEX OF G-CSF WITH ITS RECEPTOR | Descriptor: | PROTEIN (G-CSF RECEPTOR), PROTEIN (GRANULOCYTE COLONY-STIMULATING FACTOR) | Authors: | Aritomi, M, Kunishima, N, Okamoto, T, Kuroki, R, Ota, Y, Morikawa, K. | Deposit date: | 1999-03-08 | Release date: | 2000-03-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Atomic structure of the GCSF-receptor complex showing a new cytokine-receptor recognition scheme. Nature, 401, 1999
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1IT3
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![BU of 1it3 by Molmil](/molmil-images/mine/1it3) | Hagfish CO ligand hemoglobin | Descriptor: | CARBON MONOXIDE, PROTOPORPHYRIN IX CONTAINING FE, hemoglobin | Authors: | Mito, M, Chong, K.T, Park, S.-Y, Tame, J.R. | Deposit date: | 2002-01-05 | Release date: | 2002-01-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of deoxy- and carbonmonoxyhemoglobin F1 from the hagfish Eptatretus burgeri J.Biol.Chem., 277, 2002
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1IT2
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![BU of 1it2 by Molmil](/molmil-images/mine/1it2) | Hagfish deoxy hemoglobin | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, hemoglobin | Authors: | Mito, M, Chong, K.T, Park, S.-Y, Tame, J.R. | Deposit date: | 2002-01-05 | Release date: | 2002-01-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structures of deoxy- and carbonmonoxyhemoglobin F1 from the hagfish Eptatretus burgeri J.Biol.Chem., 277, 2002
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2E9L
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![BU of 2e9l by Molmil](/molmil-images/mine/2e9l) | Crystal Structure of human Cytosolic Neutral beta-Glycosylceramidase (Klotho-related Prote:KLrP) complex with Glucose and fatty acids | Descriptor: | Cytosolic beta-glucosidase, GLYCEROL, OLEIC ACID, ... | Authors: | Kakuta, Y, Hayashi, Y, Okino, N, Ito, M. | Deposit date: | 2007-01-25 | Release date: | 2007-09-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Klotho-related protein is a novel cytosolic neutral beta-glycosylceramidase. J.Biol.Chem., 282, 2007
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5MR6
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![BU of 5mr6 by Molmil](/molmil-images/mine/5mr6) | XiaF from Streptomyces sp. in complex with FADH2 and Glycerol | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, XiaF protein | Authors: | Kugel, S, Baunach, M, Baer, P, Ishida-Ito, M, Sundaram, S, Xu, Z, Groll, M, Hertweck, C. | Deposit date: | 2016-12-21 | Release date: | 2017-06-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Cryptic indole hydroxylation by a non-canonical terpenoid cyclase parallels bacterial xenobiotic detoxification. Nat Commun, 8, 2017
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5LVW
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![BU of 5lvw by Molmil](/molmil-images/mine/5lvw) | XiaF (FADH2) from Streptomyces sp. | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, INDOLE, SULFATE ION, ... | Authors: | Kugel, S, Baunach, M, Baer, P, Ishida-Ito, M, Sundaram, S, Xu, Z, Groll, M, Hertweck, C. | Deposit date: | 2016-09-14 | Release date: | 2017-06-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Cryptic indole hydroxylation by a non-canonical terpenoid cyclase parallels bacterial xenobiotic detoxification. Nat Commun, 8, 2017
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5LVU
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![BU of 5lvu by Molmil](/molmil-images/mine/5lvu) | XiaF (apo) from Streptomyces sp. | Descriptor: | SULFATE ION, XiaF protein | Authors: | Kugel, S, Baunach, M, Baer, P, Ishida-Ito, M, Sundaram, S, Xu, Z, Groll, M, Hertweck, C. | Deposit date: | 2016-09-14 | Release date: | 2017-06-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Cryptic indole hydroxylation by a non-canonical terpenoid cyclase parallels bacterial xenobiotic detoxification. Nat Commun, 8, 2017
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7F1D
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![BU of 7f1d by Molmil](/molmil-images/mine/7f1d) | Crystal Structure of BACE1 in complex with N-{3-[(4R,5R,6R)-2-amino-5-fluoro-4,6-dimethyl-5,6-dihydro-4H-1,3-thiazin-4-yl]-4-fluorophenyl}-2H,3H-[1,4]dioxino[2,3-c]pyridine-7-carboxamide | Descriptor: | Beta-secretase 1, IODIDE ION, N-[3-[(4R,5R,6R)-2-azanyl-5-fluoranyl-4,6-dimethyl-5,6-dihydro-1,3-thiazin-4-yl]-4-fluoranyl-phenyl]-2,3-dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxamide | Authors: | Ueno, T, Matsuoka, E, Asada, N, Yamamoto, S, Kanegawa, N, Ito, M, Ito, H, Moechars, D, Rombouts, F.J.R, Gijsen, H.J.M, Kusakabe, K.I. | Deposit date: | 2021-06-09 | Release date: | 2022-02-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Discovery of Extremely Selective Fused Pyridine-Derived beta-Site Amyloid Precursor Protein-Cleaving Enzyme (BACE1) Inhibitors with High In Vivo Efficacy through 10s Loop Interactions. J.Med.Chem., 64, 2021
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7F1G
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![BU of 7f1g by Molmil](/molmil-images/mine/7f1g) | BACE2 xaperone complex with N-{3-[(4R,5R,6R)-2-amino-5-fluoro-4,6-dimethyl-5,6-dihydro-4H-1,3-thiazin-4-yl]-4-fluorophenyl}-2H,3H-[1,4]dioxino[2,3-c]pyridine-7-carboxamide | Descriptor: | Beta-secretase 2, N-[3-[(4R,5R,6R)-2-azanyl-5-fluoranyl-4,6-dimethyl-5,6-dihydro-1,3-thiazin-4-yl]-4-fluoranyl-phenyl]-2,3-dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxamide, XAPERONE | Authors: | Ueno, T, Matsuoka, E, Asada, N, Yamamoto, S, Kanegawa, N, Ito, M, Ito, H, Moechars, D, Rombouts, F.J.R, Gijsen, H.J.M, Kusakabe, K.I. | Deposit date: | 2021-06-09 | Release date: | 2022-02-23 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Discovery of Extremely Selective Fused Pyridine-Derived beta-Site Amyloid Precursor Protein-Cleaving Enzyme (BACE1) Inhibitors with High In Vivo Efficacy through 10s Loop Interactions. J.Med.Chem., 64, 2021
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2E9M
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![BU of 2e9m by Molmil](/molmil-images/mine/2e9m) | Crystal Structure of human Cytosolic Neutral beta-Glycosylceramidase (Klotho-related Prote:KLrP) complex with Galactose and fatty acids | Descriptor: | Cytosolic beta-glucosidase, OLEIC ACID, PALMITIC ACID, ... | Authors: | Kakuta, Y, Hayashi, Y, Okino, N, Ito, M. | Deposit date: | 2007-01-25 | Release date: | 2007-09-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Klotho-related protein is a novel cytosolic neutral beta-glycosylceramidase. J.Biol.Chem., 282, 2007
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3GH4
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![BU of 3gh4 by Molmil](/molmil-images/mine/3gh4) | Crystal structure of beta-hexosaminidase from Paenibacillus sp. TS12 | Descriptor: | ACETIC ACID, SULFATE ION, beta-hexosaminidase | Authors: | Sumida, T, Ishii, R, Yanagisawa, T, Yokoyama, S, Ito, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2009-03-03 | Release date: | 2009-07-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular cloning and crystal structural analysis of a novel beta-N-acetylhexosaminidase from Paenibacillus sp. TS12 capable of degrading glycosphingolipids J.Mol.Biol., 392, 2009
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3GH5
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![BU of 3gh5 by Molmil](/molmil-images/mine/3gh5) | Crystal structure of beta-hexosaminidase from Paenibacillus sp. TS12 in complex with GlcNAc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, beta-hexosaminidase | Authors: | Sumida, T, Ishii, R, Yanagisawa, T, Yokoyama, S, Ito, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2009-03-03 | Release date: | 2009-07-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Molecular cloning and crystal structural analysis of a novel beta-N-acetylhexosaminidase from Paenibacillus sp. TS12 capable of degrading glycosphingolipids J.Mol.Biol., 392, 2009
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3GH7
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![BU of 3gh7 by Molmil](/molmil-images/mine/3gh7) | Crystal structure of beta-hexosaminidase from Paenibacillus sp. TS12 in complex with GalNAc | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, SULFATE ION, beta-hexosaminidase | Authors: | Sumida, T, Ishii, R, Yanagisawa, T, Yokoyama, S, Ito, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2009-03-03 | Release date: | 2009-07-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular cloning and crystal structural analysis of a novel beta-N-acetylhexosaminidase from Paenibacillus sp. TS12 capable of degrading glycosphingolipids J.Mol.Biol., 392, 2009
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2ZOX
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![BU of 2zox by Molmil](/molmil-images/mine/2zox) | Crystal Structure of the Covalent Intermediate of Human Cytosolic beta-Glucosidase | Descriptor: | 4-nitrophenyl alpha-D-glucopyranoside, Cytosolic beta-glucosidase, GLYCEROL, ... | Authors: | Noguchi, J, Hayashi, Y, Baba, Y, Okino, N, Kimura, M, Ito, M, Kakuta, Y. | Deposit date: | 2008-06-17 | Release date: | 2008-09-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the covalent intermediate of human cytosolic beta-glucosidase Biochem.Biophys.Res.Commun., 374, 2008
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2ZWI
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![BU of 2zwi by Molmil](/molmil-images/mine/2zwi) | Crystal structure of alpha/beta-Galactoside alpha-2,3-Sialyltransferase from a Luminous Marine Bacterium, Photobacterium phosphoreum | Descriptor: | Alpha-/beta-galactoside alpha-2,3-sialyltransferase, CHLORIDE ION, CYTIDINE-5'-MONOPHOSPHATE, ... | Authors: | Iwatani, T, Okino, N, Sakakura, M, Kajiwara, H, Ichikawa, M, Takakura, Y, Kimura, M, Ito, M, Yamamoto, T, Kakuta, Y. | Deposit date: | 2008-12-05 | Release date: | 2009-06-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystal structure of alpha/beta-galactoside alpha2,3-sialyltransferase from a luminous marine bacterium, Photobacterium phosphoreum Febs Lett., 583, 2009
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2Z4T
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![BU of 2z4t by Molmil](/molmil-images/mine/2z4t) | Crystal Structure of Vibrionaceae Photobacterium sp. JT-ISH-224 2,6-sialyltransferase in a Ternary Complex with Donor Product CMP and Accepter Substrate Lactose | Descriptor: | Beta-galactoside alpha-2,6-sialyltransferase, CYTIDINE-5'-MONOPHOSPHATE, GLYCEROL, ... | Authors: | Kakuta, Y, Okino, N, Kajiwara, H, Ichikawa, M, Takakura, Y, Ito, M, Yamamoto, T. | Deposit date: | 2007-06-25 | Release date: | 2008-04-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of Vibrionaceae Photobacterium sp. JT-ISH-224 alpha2,6-sialyltransferase in a ternary complex with donor product CMP and acceptor substrate lactose: catalytic mechanism and substrate recognition Glycobiology, 18, 2008
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2ZSC
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![BU of 2zsc by Molmil](/molmil-images/mine/2zsc) | Tamavidin2, Novel Avidin-like Biotin-Binding Proteins from an Edible Mushroom | Descriptor: | BIOTIN, GLYCEROL, MAGNESIUM ION, ... | Authors: | Kakuta, Y, Okino, N, Ito, M, Yamamoto, T, Takakura, Y. | Deposit date: | 2008-09-05 | Release date: | 2009-02-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Tamavidins--novel avidin-like biotin-binding proteins from the Tamogitake mushroom Febs J., 276, 2009
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2ZWS
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![BU of 2zws by Molmil](/molmil-images/mine/2zws) | Crystal Structure Analysis of neutral ceramidase from Pseudomonas aeruginosa | Descriptor: | FORMIC ACID, GLYCEROL, MAGNESIUM ION, ... | Authors: | Kakuta, Y, Okino, N, Inoue, T, Okano, H, Ito, M. | Deposit date: | 2008-12-17 | Release date: | 2009-03-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Mechanistic insights into the hydrolysis and synthesis of ceramide by neutral ceramidase. J.Biol.Chem., 284, 2009
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2ZXC
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![BU of 2zxc by Molmil](/molmil-images/mine/2zxc) | Ceramidase complexed with C2 | Descriptor: | DIMETHYL SULFOXIDE, FORMIC ACID, MAGNESIUM ION, ... | Authors: | Okano, H, Inoue, T, Okino, N, Kakuta, Y, Matsumura, H, Ito, M. | Deposit date: | 2008-12-22 | Release date: | 2009-02-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mechanistic insights into the hydrolysis and synthesis of ceramide by neutral ceramidase. J.Biol.Chem., 284, 2009
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3VKK
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![BU of 3vkk by Molmil](/molmil-images/mine/3vkk) | Crystal Structure Of The Covalent Intermediate Of Human Cytosolic Beta-Glucosidase-mannose complex | Descriptor: | CHLORIDE ION, Cytosolic beta-glucosidase, GLYCEROL, ... | Authors: | Noguchi, J, Hayashi, Y, Okino, N, Ito, M, Kimura, M, Kakuta, Y. | Deposit date: | 2011-11-17 | Release date: | 2012-11-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for inhibition mechanism of human cytosolic beta-glucosidase by monnoside To be Published
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1V8X
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![BU of 1v8x by Molmil](/molmil-images/mine/1v8x) | Crystal Structure of the Dioxygen-bound Heme Oxygenase from Corynebacterium diphtheriae | Descriptor: | Heme oxygenase, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Unno, M, Matsui, T, Chu, G.C, Couture, M, Yoshida, T, Rousseau, D.L, Olson, J.S, Ikeda-Saito, M. | Deposit date: | 2004-01-15 | Release date: | 2004-05-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal Structure of the Dioxygen-bound Heme Oxygenase from Corynebacterium diphtheriae: IMPLICATIONS FOR HEME OXYGENASE FUNCTION. J.Biol.Chem., 279, 2004
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1WZF
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![BU of 1wzf by Molmil](/molmil-images/mine/1wzf) | Crystal Structure Of An Artificial Metalloprotein: Fe(10-COOH-Salophen)/Wild Type Heme oxygenase | Descriptor: | GLYCEROL, Heme oxygenase, SULFATE ION, ... | Authors: | Unno, M, Yokoi, N, Ueno, T, Watanabe, Y, Ikeda-Saito, M. | Deposit date: | 2005-03-04 | Release date: | 2006-02-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Design of metal cofactors activated by a protein-protein electron transfer system. Proc.Natl.Acad.Sci.Usa, 103, 2006
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