5V1X
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![BU of 5v1x by Molmil](/molmil-images/mine/5v1x) | Carbon Sulfoxide lyase, Egt2 Y134F in complex with its substrate | Descriptor: | (1S)-2-{2-[(R)-(2R)-2-amino-2-carboxyethanesulfinyl]-1H-imidazol-4-yl}-1-carboxy-N,N,N-trimethylethan-1-aminium, FORMIC ACID, Hercynylcysteine sulfoxide lyase | Authors: | Irani, S, Zhang, Y. | Deposit date: | 2017-03-02 | Release date: | 2018-03-07 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.558 Å) | Cite: | Snapshots of C-S Cleavage in Egt2 Reveals Substrate Specificity and Reaction Mechanism. Cell Chem Biol, 25, 2018
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5UTS
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5V12
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![BU of 5v12 by Molmil](/molmil-images/mine/5v12) | Crystal structure of Carbon Sulfoxide lyase, Egt2 Y134F with sulfenic acid intermediate | Descriptor: | (1S)-1-carboxy-2-[2-(hydroxysulfanyl)-1H-imidazol-4-yl]-N,N,N-trimethylethan-1-aminium, FORMIC ACID, Hercynylcysteine sulfoxide lyase | Authors: | Irani, S, Zhang, Y. | Deposit date: | 2017-03-01 | Release date: | 2018-03-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.451 Å) | Cite: | Snapshots of C-S Cleavage in Egt2 Reveals Substrate Specificity and Reaction Mechanism. Cell Chem Biol, 25, 2018
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6NPW
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![BU of 6npw by Molmil](/molmil-images/mine/6npw) | SSu72/Sympk in complex with Ser2/Ser5 phosphorylated peptide | Descriptor: | PHOSPHATE ION, Ser2/Ser5 phosphorylated peptide, Ssu72 ortholog, ... | Authors: | Irani, S, Zhang, Y. | Deposit date: | 2019-01-18 | Release date: | 2019-04-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.486 Å) | Cite: | Structural determinants for accurate dephosphorylation of RNA polymerase II by its cognate C-terminal domain (CTD) phosphatase during eukaryotic transcription. J.Biol.Chem., 294, 2019
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6O6L
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![BU of 6o6l by Molmil](/molmil-images/mine/6o6l) | The Structure of EgtB(Cabther) in complex with Hercynine | Descriptor: | EgtB (Cabther), FE (III) ION, N,N,N-trimethyl-histidine | Authors: | Irani, S, Zhang, Y. | Deposit date: | 2019-03-07 | Release date: | 2019-07-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal Structure of the Ergothioneine Sulfoxide Synthase fromCandidatus Chloracidobacterium thermophilumand Structure-Guided Engineering To Modulate Its Substrate Selectivity. Acs Catalysis, 9, 2019
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6O6M
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![BU of 6o6m by Molmil](/molmil-images/mine/6o6m) | The Structure of EgtB (Cabther) | Descriptor: | EgtB (Cabther), FE (III) ION, GLYCEROL | Authors: | Irani, S, Zhang, Y. | Deposit date: | 2019-03-07 | Release date: | 2019-07-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.506 Å) | Cite: | Crystal Structure of the Ergothioneine Sulfoxide Synthase fromCandidatus Chloracidobacterium thermophilumand Structure-Guided Engineering To Modulate Its Substrate Selectivity. Acs Catalysis, 9, 2019
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5C2Y
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![BU of 5c2y by Molmil](/molmil-images/mine/5c2y) | Crystal structure of the Saccharomyces cerevisiae Rtr1 (regulator of transcription) | Descriptor: | GLYCEROL, RNA polymerase II subunit B1 CTD phosphatase RTR1, SULFATE ION, ... | Authors: | Yogesha, S.D, Irani, S, Zhang, Y.J. | Deposit date: | 2015-06-16 | Release date: | 2016-05-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of Saccharomyces cerevisiae Rtr1 reveals an active site for an atypical phosphatase. Sci.Signal., 9, 2016
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6DU3
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![BU of 6du3 by Molmil](/molmil-images/mine/6du3) | Structure of Scp1 D96N bound to REST-pS861/4 peptide | Descriptor: | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, REST-pS861 | Authors: | Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J. | Deposit date: | 2018-06-19 | Release date: | 2018-09-26 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST). J. Biol. Chem., 293, 2018
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6DU2
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![BU of 6du2 by Molmil](/molmil-images/mine/6du2) | Structure of Scp1 D96N bound to REST-pS861/4 peptide | Descriptor: | MAGNESIUM ION, REST-pS861/4, carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X2 | Authors: | Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J. | Deposit date: | 2018-06-19 | Release date: | 2018-09-26 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST). J. Biol. Chem., 293, 2018
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6OVG
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6NKO
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![BU of 6nko by Molmil](/molmil-images/mine/6nko) | Crystal structure of ForH | Descriptor: | ForH | Authors: | Zheng, J, Irani, S, Zhang, Y. | Deposit date: | 2019-01-07 | Release date: | 2019-04-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Identification of the Formycin A Biosynthetic Gene Cluster from Streptomyces kaniharaensis Illustrates the Interplay between Biological Pyrazolopyrimidine Formation and de Novo Purine Biosynthesis. J. Am. Chem. Soc., 141, 2019
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