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PDB: 356 results

8TVU
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BU of 8tvu by Molmil
In situ cryo-EM structure of bacteriophage P22 portal protein: head-to-tail protein complex at 3.0A resolution
Descriptor: Peptidoglycan hydrolase gp4, Portal protein
Authors:Iglesias, S.M, Cingolani, G, Feng-Hou, C.
Deposit date:2023-08-18
Release date:2023-11-29
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular Architecture of Salmonella Typhimurium Virus P22 Genome Ejection Machinery.
J.Mol.Biol., 435, 2023
8TVR
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BU of 8tvr by Molmil
In situ cryo-EM structure of bacteriophage P22 tail hub protein: tailspike protein complex at 2.8A resolution
Descriptor: Packaged DNA stabilization protein gp10, Tail spike protein
Authors:Iglesias, S, Cingolani, G, Feng-Hou, C.
Deposit date:2023-08-18
Release date:2023-11-29
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Molecular Architecture of Salmonella Typhimurium Virus P22 Genome Ejection Machinery.
J.Mol.Biol., 435, 2023
3L25
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BU of 3l25 by Molmil
Crystal structure of Zaire Ebola VP35 interferon inhibitory domain bound to 8 bp dsRNA
Descriptor: CHLORIDE ION, FORMIC ACID, GLYCEROL, ...
Authors:Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K.
Deposit date:2009-12-14
Release date:2010-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.
Nat.Struct.Mol.Biol., 17, 2010
6E4D
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BU of 6e4d by Molmil
Atomic structure of Mycobacterium tuberculosis DppA
Descriptor: Periplasmic dipeptide-binding lipoprotein DPPA, VAL-VAL-VAL-ALA
Authors:Ko, Y, Mitra, A, Niederweis, M, Cingolani, G.
Deposit date:2018-07-17
Release date:2019-09-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.252 Å)
Cite:Heme and hemoglobin utilization by Mycobacterium tuberculosis.
Nat Commun, 10, 2019
3L27
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BU of 3l27 by Molmil
Crystal structure of Zaire Ebola VP35 interferon inhibitory domain R312A mutant
Descriptor: CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ...
Authors:Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K.
Deposit date:2009-12-14
Release date:2010-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.
Nat.Struct.Mol.Biol., 17, 2010
1F4K
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BU of 1f4k by Molmil
CRYSTAL STRUCTURE OF THE REPLICATION TERMINATOR PROTEIN/B-SITE DNA COMPLEX
Descriptor: 5'-D(*CP*TP*AP*TP*GP*AP*AP*CP*AP*TP*AP*AP*TP*GP*TP*TP*CP*AP*TP*AP*G)-3', 5'-D(*CP*TP*AP*TP*GP*AP*AP*CP*AP*TP*TP*AP*TP*GP*TP*TP*CP*AP*TP*AP*G)-3', REPLICATION TERMINATION PROTEIN
Authors:Wilce, J.A, Vivian, J.P, Hastings, A.F, Otting, G, Folmer, R.H.A, Duggin, I.G, Wake, R.G, Wilce, M.C.J.
Deposit date:2000-06-08
Release date:2001-06-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the RTP-DNA complex and the mechanism of polar replication fork arrest
Nat.Struct.Biol., 8, 2001
4ZKP
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BU of 4zkp by Molmil
P22 Tail Needle Gp26 crystallized at pH 7.0
Descriptor: CALCIUM ION, CHLORIDE ION, Tail needle protein gp26
Authors:Sankhala, R.S, Cingolani, G.
Deposit date:2015-04-30
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions.
J.Biol.Chem., 291, 2016
3LQF
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BU of 3lqf by Molmil
Crystal structure of the short-chain dehydrogenase Galactitol-Dehydrogenase (GatDH) of Rhodobacter sphaeroides in complex with NAD and erythritol
Descriptor: Galactitol dehydrogenase, MAGNESIUM ION, MESO-ERYTHRITOL, ...
Authors:Carius, Y, Christian, H, Faust, A, Kornberger, P, Zander, U, Klink, B.U, Kohring, G.W, Giffhorn, F, Scheidig, A.J.
Deposit date:2010-02-09
Release date:2010-04-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insight into substrate differentiation of the sugar-metabolizing enzyme galactitol dehydrogenase from Rhodobacter sphaeroides D.
J.Biol.Chem., 285, 2010
8GCN
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BU of 8gcn by Molmil
CRYO-EM STRUCTURE OF IMPORTIN ALPHA1/BETA HETERODIMER
Descriptor: Importin subunit alpha-1, Importin subunit beta-1
Authors:Ko, Y, Cingolani, G.
Deposit date:2023-03-02
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:CRYO-EM STRUCTURE OF IMPORTIN ALPHA1/BETA HETERODIMER
To Be Published
7UKJ
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BU of 7ukj by Molmil
In situ cryo-EM structure of bacteriophage Sf6 portal:gp7 complex at 2.7A resolution
Descriptor: Gene 14 protein
Authors:Li, F, Cingolani, G, Hou, C.
Deposit date:2022-04-01
Release date:2022-12-21
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:High-resolution cryo-EM structure of the Shigella virus Sf6 genome delivery tail machine.
Sci Adv, 8, 2022
1LJY
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BU of 1ljy by Molmil
Crystal Structure of a Novel Regulatory 40 kDa Mammary Gland Protein (MGP-40) secreted during Involution
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MGP-40
Authors:Mohanty, A.K, Singh, G, Paramasivam, M, Saravanan, K, Jabeen, T, Sharma, S, Yadav, S, Kaur, P, Kumar, P, Srinivasan, A, Singh, T.P.
Deposit date:2002-04-23
Release date:2003-03-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of a Novel Regulatory 40 kDa Mammary Gland Protein (MGP-40) secreted during Involution
J.Biol.Chem., 278, 2003
3LWW
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BU of 3lww by Molmil
Structure of an open and closed conformation of Human Importin Beta bound to the Snurportin1 IBB-domain trapped in the same crystallographic asymmetric unit
Descriptor: Importin subunit beta-1, Snurportin-1
Authors:Bhardwaj, A, Cingolani, G.
Deposit date:2010-02-24
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Conformational selection in the recognition of the snurportin importin beta binding domain by importin beta.
Biochemistry, 49, 2010
7UMI
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BU of 7umi by Molmil
Importin a1 bound to Cp183-CTD
Descriptor: HBV-NLS, Importin subunit alpha-1
Authors:Yang, R, Cingolani, G.
Deposit date:2022-04-07
Release date:2023-10-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core.
Sci Adv, 10, 2024
1HY7
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BU of 1hy7 by Molmil
A CARBOXYLIC ACID BASED INHIBITOR IN COMPLEX WITH MMP3
Descriptor: CALCIUM ION, R-2-{[4'-METHOXY-(1,1'-BIPHENYL)-4-YL]-SULFONYL}-AMINO-6-METHOXY-HEX-4-YNOIC ACID, STROMELYSIN-1, ...
Authors:Natchus, M.G, Bookland, R.G, Laufersweiler, M.J, Pikul, S, Almstead, N.G, De, B, Janusz, M.J, Hsieh, L.C, Gu, F, Pokross, M.E, Patel, V.S, Garver, S.M, Peng, S.X, Branch, T.M, King, S.L, Baker, T.R, Foltz, D.J, Mieling, G.E.
Deposit date:2001-01-18
Release date:2002-01-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Development of new carboxylic acid-based MMP inhibitors derived from functionalized propargylglycines.
J.Med.Chem., 44, 2001
4ZKU
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BU of 4zku by Molmil
P22 Tail Needle Gp26 crystallized at pH 10.0
Descriptor: CALCIUM ION, CHLORIDE ION, Tail needle protein gp26
Authors:Sankhala, R.S, Cingolani, G.
Deposit date:2015-04-30
Release date:2015-06-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions.
J.Biol.Chem., 291, 2016
4ZXQ
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BU of 4zxq by Molmil
P22 Tail Needle Gp26 1-140 crystallized at pH 3.9
Descriptor: CALCIUM ION, CHLORIDE ION, Tail needle protein gp26
Authors:Sankhala, R.S, Cingolani, G.
Deposit date:2015-05-20
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions.
J.Biol.Chem., 291, 2016
5BU5
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BU of 5bu5 by Molmil
HK620 Tail Needle crystallized at pH 9 (crystal form I)
Descriptor: CALCIUM ION, CHLORIDE ION, DNA stabilization protein
Authors:Bhardwaj, A, Cingolani, G.
Deposit date:2015-06-03
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.952 Å)
Cite:Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions.
J.Biol.Chem., 291, 2016
4CDX
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BU of 4cdx by Molmil
Crystal structure of human Enterovirus 71 in complex with the uncoating inhibitor GPP12
Descriptor: 1-(5-((3'-METHYL-[1,1'-BIPHENYL]-4-YL)OXY)PENTYL)-3-(, SODIUM ION, VP1, ...
Authors:De Colibus, L, Wang, X, Spyrou, J.A.B, Kelly, J, Ren, J, Grimes, J, Puerstinger, G, Stonehouse, N, Walter, T.S, Hu, Z, Wang, J, Li, X, Peng, W, Rowlands, D, Fry, E.E, Rao, Z, Stuart, D.I.
Deposit date:2013-11-07
Release date:2014-02-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules.
Nat.Struct.Mol.Biol., 21, 2014
4CDW
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BU of 4cdw by Molmil
Crystal structure of human Enterovirus 71 in complex with the uncoating inhibitor GPP4
Descriptor: 1-[(3S)-5-(4-iodanylphenoxy)-3-methyl-pentyl]-3-pyridin-4-yl-imidazolidin-2-one, SODIUM ION, VP1, ...
Authors:De Colibus, L, Wang, X, Spyrou, J.A.B, Kelly, J, Ren, J, Grimes, J, Puerstinger, G, Stonehouse, N, Walter, T.S, Hu, Z, Wang, J, Li, X, Peng, W, Rowlands, D, Fry, E.E, Rao, Z, Stuart, D.I.
Deposit date:2013-11-06
Release date:2014-02-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules
Nat.Struct.Mol.Biol., 21, 2014
2YAK
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BU of 2yak by Molmil
Structure of death-associated protein Kinase 1 (dapk1) in complex with a ruthenium octasporine ligand (OSV)
Descriptor: DEATH-ASSOCIATED PROTEIN KINASE 1, RUTHENIUM OCTASPORINE 4
Authors:Feng, L, Geisselbrecht, Y, Blanck, S, Wilbuer, A, Atilla-Gokcumen, G.E, Filippakopoulos, P, Kraeling, K, Celik, M.A, Harms, K, Maksimoska, J, Marmorstein, R, Frenking, G, Knapp, S, Essen, L.-O, Meggers, E.
Deposit date:2011-02-23
Release date:2011-04-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors.
J.Am.Chem.Soc., 133, 2011
5BU8
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BU of 5bu8 by Molmil
HK620 Tail Needle crystallized at pH 7.5 and derivatized with Xenon
Descriptor: CALCIUM ION, DNA stabilization protein, XENON
Authors:Sankhala, R.S, Cingolani, G.
Deposit date:2015-06-03
Release date:2015-11-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions.
J.Biol.Chem., 291, 2016
8U1O
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BU of 8u1o by Molmil
In situ cryo-EM structure of bacteriophage P22 tailspike protein complex at 3.4A resolution
Descriptor: Tail spike protein
Authors:Iglesias, S.M, Feng-Hou, C, Cingolani, G.
Deposit date:2023-09-01
Release date:2023-11-29
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular Architecture of Salmonella Typhimurium Virus P22 Genome Ejection Machinery.
J.Mol.Biol., 435, 2023
1AHD
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BU of 1ahd by Molmil
DETERMINATION OF THE NMR SOLUTION STRUCTURE OF AN ANTENNAPEDIA HOMEODOMAIN-DNA COMPLEX
Descriptor: DNA (5'-D(*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*AP*GP*CP*CP*AP*TP*TP*AP*GP*AP*G)-3'), Homeotic protein antennapedia
Authors:Billeter, M, Qian, Y.Q, Otting, G, Muller, M, Gehring, W.J, Wuthrich, K.
Deposit date:1993-04-02
Release date:1993-10-31
Last modified:2024-04-10
Method:SOLUTION NMR
Cite:Determination of the nuclear magnetic resonance solution structure of an Antennapedia homeodomain-DNA complex.
J.Mol.Biol., 234, 1993
6V6T
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BU of 6v6t by Molmil
Solution structure of delta-theraphotoxin-Hm1b from Heteroscodra maculata
Descriptor: Delta-theraphotoxin-Hm1b
Authors:Chin, Y.K.Y, Chow, C.Y, King, G.F.
Deposit date:2019-12-05
Release date:2020-05-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A selective Na V 1.1 activator with potential for treatment of Dravet syndrome epilepsy.
Biochem Pharmacol, 181, 2020
7K5C
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BU of 7k5c by Molmil
Structure of T7 DNA ejectosome periplasmic tunnel
Descriptor: Internal virion protein gp15, Peptidoglycan transglycosylase gp16
Authors:Swanson, N, Cingolani, G, Pumroy, R.
Deposit date:2020-09-16
Release date:2021-07-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM structure of the periplasmic tunnel of T7 DNA-ejectosome at 2.7 angstrom resolution.
Mol.Cell, 81, 2021

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