5Y2O
 
 | | Structure of PPARgamma ligand binding domain-pioglitazone complex | | Descriptor: | (5S)-5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma | | Authors: | Im, Y.J, Lee, M. | | Deposit date: | 2017-07-26 | | Release date: | 2017-12-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.801 Å) | | Cite: | Structures of PPAR gamma complexed with lobeglitazone and pioglitazone reveal key determinants for the recognition of antidiabetic drugs
Sci Rep, 7, 2017
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5H2C
 | | Crystal structure of Saccharomyces cerevisiae Osh1 ANK - Nvj1 | | Descriptor: | Nucleus-vacuole junction protein 1, Oxysterol-binding protein homolog 1 | | Authors: | Im, Y.J, Manik, M.K, Yang, H.S, Tong, J.S. | | Deposit date: | 2016-10-14 | | Release date: | 2017-05-10 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.508 Å) | | Cite: | Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction
Structure, 25, 2017
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4R0Y
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5H2D
 | | Crystal structure of Osh1 ORD domain in complex with ergosterol | | Descriptor: | ERGOSTEROL, KLLA0C04147p, SULFATE ION | | Authors: | Im, Y.J, Manik, M.K, Yang, H.S, Tong, J.S. | | Deposit date: | 2016-10-14 | | Release date: | 2017-05-10 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction
Structure, 25, 2017
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5H2A
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5H28
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5YQJ
 | | Crystal structure of the first StARkin domain of Lam4 | | Descriptor: | Membrane-anchored lipid-binding protein LAM4 | | Authors: | Im, Y.J, Tong, J.S. | | Deposit date: | 2017-11-06 | | Release date: | 2018-01-31 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural basis of sterol recognition and nonvesicular transport by lipid transfer proteins anchored at membrane contact sites
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5WVR
 | | Crystal structure of Osh1 ORD domain in complex with cholesterol | | Descriptor: | CHOLESTEROL, KLLA0C04147p, SULFATE ION | | Authors: | Im, Y.J, Manik, M.K, Yang, H.S, Tong, J.S. | | Deposit date: | 2016-12-28 | | Release date: | 2017-05-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction
Structure, 25, 2017
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7DEI
 | | Structure of human ORP3 ORD domain in complex with PI(4)P | | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, Oxysterol-binding protein-related protein 3 | | Authors: | Tong, J, Tan, L, Im, Y.J. | | Deposit date: | 2020-11-04 | | Release date: | 2021-03-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of human ORP3 ORD reveals conservation of a key function and ligand specificity in OSBP-related proteins.
Plos One, 16, 2021
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7DEJ
 | | Structure of human ORP3 ORD in apo-form | | Descriptor: | Oxysterol-binding protein-related protein 3 | | Authors: | Tong, J, Tan, L, Im, Y.J. | | Deposit date: | 2020-11-04 | | Release date: | 2021-03-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure of human ORP3 ORD reveals conservation of a key function and ligand specificity in OSBP-related proteins.
Plos One, 16, 2021
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6WCW
 | | Structure of human Rubicon RH domain in complex with GTP-bound Rab7 | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-7a, ... | | Authors: | Bhargava, H.K, Byck, J.M, Farrell, D.P, Anishchenko, I, DiMaio, F, Im, Y.J, Hurley, J.H. | | Deposit date: | 2020-03-31 | | Release date: | 2020-07-01 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis for autophagy inhibition by the human Rubicon-Rab7 complex.
Proc.Natl.Acad.Sci.USA, 117, 2020
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5AYY
 | | CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE REACTANT QUINOLINATE | | Descriptor: | Nicotinate-nucleotide pyrophosphorylase [carboxylating], QUINOLINIC ACID | | Authors: | Youn, H.S, Kim, T.G, Kim, M.K, Kang, G.B, Kang, J.Y, Seo, Y.J, Lee, J.G, An, J.Y, Park, K.R, Lee, Y, Im, Y.J, Lee, J.H, Fukuoka, S.I, Eom, S.H. | | Deposit date: | 2015-09-14 | | Release date: | 2016-02-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.09 Å) | | Cite: | Structural Insights into the Quaternary Catalytic Mechanism of Hexameric Human Quinolinate Phosphoribosyltransferase, a Key Enzyme in de novo NAD Biosynthesis
Sci Rep, 6, 2016
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5AYZ
 | | CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE PRODUCT NICOTINATE MONONUCLEOTIDE | | Descriptor: | NICOTINATE MONONUCLEOTIDE, Nicotinate-nucleotide pyrophosphorylase [carboxylating] | | Authors: | Youn, H.S, Kim, T.G, Kim, M.K, Kang, G.B, Kang, J.Y, Seo, Y.J, Lee, J.G, An, J.Y, Park, K.R, Lee, Y, Im, Y.J, Lee, J.H, Fukuoka, S.I, Eom, S.H. | | Deposit date: | 2015-09-14 | | Release date: | 2016-02-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural Insights into the Quaternary Catalytic Mechanism of Hexameric Human Quinolinate Phosphoribosyltransferase, a Key Enzyme in de novo NAD Biosynthesis
Sci Rep, 6, 2016
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3G9H
 | | Crystal structure of the C-terminal mu homology domain of Syp1 | | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Suppressor of yeast profilin deletion | | Authors: | Reider, A, Barker, S, Mishra, S, Im, Y.J, Maldonado-Baez, L, Hurley, J, Traub, L, Wendland, B. | | Deposit date: | 2009-02-13 | | Release date: | 2009-09-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Syp1 is a conserved endocytic adaptor that contains domains involved in cargo selection and membrane tubulation.
Embo J., 28, 2009
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3G9G
 | | Crystal Structure of the N-terminal EFC/F-BAR domain of Syp1 | | Descriptor: | Suppressor of yeast profilin deletion | | Authors: | Reider, A, Barker, S, Mishra, S, Im, Y.J, Maldonado-Baez, L, Hurley, J, Traub, L, Wendland, B. | | Deposit date: | 2009-02-13 | | Release date: | 2009-09-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Syp1 is a conserved endocytic adaptor that contains domains involved in cargo selection and membrane tubulation.
Embo J., 28, 2009
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1G4B
 | | CRYSTAL STRUCTURES OF THE HSLVU PEPTIDASE-ATPASE COMPLEX REVEAL AN ATP-DEPENDENT PROTEOLYSIS MECHANISM | | Descriptor: | ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ATP-DEPENDENT PROTEASE HSLV | | Authors: | Wang, J, Song, J.J, Franklin, M.C, Kamtekar, S, Im, Y.J, Rho, S.H, Seong, I.S, Lee, C.S, Chung, C.H, Eom, S.H. | | Deposit date: | 2000-10-26 | | Release date: | 2001-02-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (7 Å) | | Cite: | Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism.
Structure, 9, 2001
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1G4A
 | | CRYSTAL STRUCTURES OF THE HSLVU PEPTIDASE-ATPASE COMPLEX REVEAL AN ATP-DEPENDENT PROTEOLYSIS MECHANISM | | Descriptor: | 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ATP-DEPENDENT PROTEASE HSLV | | Authors: | Wang, J, Song, J.J, Franklin, M.C, Kamtekar, S, Im, Y.J, Rho, S.H, Seong, I.S, Lee, C.S, Chung, C.H, Eom, S.H. | | Deposit date: | 2000-10-26 | | Release date: | 2001-02-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism.
Structure, 9, 2001
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4IAP
 | | Crystal structure of PH domain of Osh3 from Saccharomyces cerevisiae | | Descriptor: | Oxysterol-binding protein homolog 3,Endolysin,Oxysterol-binding protein homolog 3, SULFATE ION | | Authors: | Tong, J, Im, Y.J. | | Deposit date: | 2012-12-07 | | Release date: | 2013-07-31 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins
Structure, 21, 2013
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4INQ
 | | Crystal structure of Osh3 ORD in complex with PI(4)P from Saccharomyces cerevisiae | | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, Oxysterol-binding protein homolog 3 | | Authors: | Tong, J, Im, Y.J. | | Deposit date: | 2013-01-05 | | Release date: | 2013-07-31 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins
Structure, 21, 2013
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4IC4
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4J7P
 | | Crystal structure of Saccharomyces cerevisiae Sfh3 | | Descriptor: | Phosphatidylinositol transfer protein PDR16 | | Authors: | Yang, H, Im, Y.J. | | Deposit date: | 2013-02-14 | | Release date: | 2013-07-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural determinants for phosphatidylinositol recognition by Sfh3 and substrate-induced dimer-monomer transition during lipid transfer cycles.
Febs Lett., 587, 2013
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2IE8
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4J7Q
 | | Crystal structure of Saccharomyces cerevisiae Sfh3 complexed with phosphatidylinositol | | Descriptor: | (1R)-2-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Phosphatidylinositol transfer protein PDR16 | | Authors: | Yang, H, Im, Y.J. | | Deposit date: | 2013-02-14 | | Release date: | 2013-07-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural determinants for phosphatidylinositol recognition by Sfh3 and substrate-induced dimer-monomer transition during lipid transfer cycles.
Febs Lett., 587, 2013
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2B7Q
 | | Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori with nicotinate mononucleotide | | Descriptor: | NICOTINATE MONONUCLEOTIDE, Probable nicotinate-nucleotide pyrophosphorylase | | Authors: | Kim, M.K, Im, Y.J, Lee, J.H, Eom, S.H. | | Deposit date: | 2005-10-05 | | Release date: | 2006-02-21 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.31 Å) | | Cite: | Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori
Proteins, 63, 2006
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2B7P
 | | Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori with phthalic acid | | Descriptor: | PHTHALIC ACID, Probable nicotinate-nucleotide pyrophosphorylase, SULFATE ION | | Authors: | Kim, M.K, Im, Y.J, Lee, J.H, Eom, S.H. | | Deposit date: | 2005-10-05 | | Release date: | 2006-02-14 | | Last modified: | 2018-09-19 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori
Proteins, 63, 2006
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