1K1U
 
 | | Combining Mutations in HIV-1 Protease to Understand Mechanisms of Resistance | | Descriptor: | N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide, PROTEASE RETROPEPSIN | | Authors: | Mahalingam, B, Boross, P, Wang, Y.-F, Louis, J.M, Fischer, C, Tozser, J, W Harrison, R, Weber, I.T. | | Deposit date: | 2001-09-25 | | Release date: | 2002-07-10 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Combining mutations in HIV-1 protease to understand mechanisms of resistance.
Proteins, 48, 2002
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1SSF
 | | Solution structure of the mouse 53BP1 fragment (residues 1463-1617) | | Descriptor: | Transformation related protein 53 binding protein 1 | | Authors: | Charier, G, Couprie, J, Alpha-Bazin, B, Meyer, V, Quemeneur, E, Guerois, R, Callebaut, I, Gilquin, B, Zinn-Justin, S. | | Deposit date: | 2004-03-24 | | Release date: | 2004-09-14 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The Tudor Tandem of 53BP1; A New Structural Motif Involved in DNA and RG-Rich Peptide Binding
Structure, 12, 2004
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5Z0Z
 | | Crystal structure of shaft pilin spaD from Lactobacillus rhamnosus GG - D242A mutant | | Descriptor: | Pilus assembly protein | | Authors: | Chaurasia, P, Pratap, S, Palva, A, von Ossowski, I, Krishnan, V. | | Deposit date: | 2017-12-22 | | Release date: | 2018-06-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.47 Å) | | Cite: | Bent conformation of a backbone pilin N-terminal domain supports a three-stage pilus assembly mechanism.
Commun Biol, 1, 2018
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5DYR
 | | Structure of virulence-associated protein D (VapD) from Xylella fastidiosa | | Descriptor: | Virulence-associated protein D | | Authors: | Kochneva, M.V, dos Santos, M.L, dos Santos, C.A, de Souza, A.P, Polikarpov, I, Aparicio, R, Golubev, A.M. | | Deposit date: | 2015-09-25 | | Release date: | 2016-01-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of virulence-associated protein D (VapD) from Xylella fastidiosa
To Be Published
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5UKQ
 | | Structure of unliganded anti-gp120 CD4bs antibody DH522.2 Fab | | Descriptor: | DH522.2 Fab fragment heavy chain, DH522.2 Fab fragment light chain, GLYCEROL | | Authors: | Nicely, N.I. | | Deposit date: | 2017-01-23 | | Release date: | 2017-12-06 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations.
Nat Commun, 8, 2017
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2YDG
 | | Ascorbate co-crystallized HEWL. | | Descriptor: | ASCORBIC ACID, Lysozyme C, SODIUM ION | | Authors: | De la Mora, E, Carmichael, I, Garman, E.F. | | Deposit date: | 2011-03-19 | | Release date: | 2011-07-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Effective Scavenging at Cryotemperatures: Further Increasing the Dose Tolerance of Protein Crystals.
J.Synchrotron.Radiat., 18, 2011
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1JHR
 | | Three-dimensional Structure of CobT in Complex with Reaction Products of 2-hydroxypurine and NaMN | | Descriptor: | N7-(5'-PHOSPHO-ALPHA-RIBOSYL)-2-HYDROXYPURINE, NICOTINIC ACID, Nicotinate Mononucleotide:5,6-Dimethylbenzimidazole Phosphoribosyltransferase | | Authors: | Cheong, C.G, Escalante-Semerena, J, Rayment, I. | | Deposit date: | 2001-06-28 | | Release date: | 2001-10-18 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural investigation of the biosynthesis of alternative lower ligands for cobamides by nicotinate mononucleotide: 5,6-dimethylbenzimidazole phosphoribosyltransferase from Salmonella enterica.
J.Biol.Chem., 276, 2001
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2Y9Q
 | | Crystal structure of human ERK2 complexed with a MAPK docking peptide | | Descriptor: | MAP KINASE-INTERACTING SERINE/THREONINE-PROTEIN KINASE 1, MITOGEN-ACTIVATED PROTEIN KINASE 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Barkai, T, Garai, A, Toeroe, I, Remenyi, A. | | Deposit date: | 2011-02-16 | | Release date: | 2012-02-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Specificity of Linear Motifs that Bind to a Common Mitogen-Activated Protein Kinase Docking Groove.
Sci. Signal, 5, 2012
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2EX8
 | | Crystal structure of penicillin binding protein 4 (dacB) from Escherichia coli, complexed with penicillin-G | | Descriptor: | OPEN FORM - PENICILLIN G, Penicillin-binding protein 4 | | Authors: | Kishida, H, Unzai, S, Roper, D.I, Lloyd, A, Park, S.-Y, Tame, J.R.H. | | Deposit date: | 2005-11-08 | | Release date: | 2006-06-13 | | Last modified: | 2016-10-19 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structure of penicillin binding protein 4 (dacB) from Escherichia coli, both in the native form and covalently linked to various antibiotics
Biochemistry, 45, 2006
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1JT2
 | | STRUCTURAL BASIS FOR THE SUBSTRATE SPECIFICITY OF THE FERUL DOMAIN OF THE CELLULOSOMAL XYLANASE Z FROM C. THERMOCELLUM | | Descriptor: | 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, PROTEIN (ENDO-1,4-BETA-XYLANASE Z) | | Authors: | Schubot, F.D, Kataeva, I.A, Blum, D.L, Shah, A.K, Ljungdahl, L.G, Rose, J.P, Wang, B.-C. | | Deposit date: | 2001-08-20 | | Release date: | 2002-03-27 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for the substrate specificity of the feruloyl esterase domain of the cellulosomal xylanase Z from Clostridium thermocellum.
Biochemistry, 40, 2001
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1JT3
 | | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Histidine Tag AND LEU 73 REPLACED BY VAL (L73V) | | Descriptor: | SULFATE ION, acidic fibroblast growth factor | | Authors: | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | | Deposit date: | 2001-08-20 | | Release date: | 2001-12-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil.
Protein Sci., 10, 2001
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3HYD
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2EX9
 | | Crystal structure of penicillin binding protein 4 (dacB) from Escherichia coli, complexed with penicillin-V | | Descriptor: | (2R,4S)-5,5-dimethyl-2-{(1R)-2-oxo-1-[(phenoxyacetyl)amino]ethyl}-1,3-thiazolidine-4-carboxylic acid, GLYCEROL, Penicillin-binding protein 4 | | Authors: | Kishida, H, Unzai, S, Roper, D.I, Lloyd, A, Park, S.-Y, Tame, J.R.H. | | Deposit date: | 2005-11-08 | | Release date: | 2006-06-13 | | Last modified: | 2016-10-19 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystal structure of penicillin binding protein 4 (dacB) from Escherichia coli, both in the native form and covalently linked to various antibiotics
Biochemistry, 45, 2006
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2Y78
 | | Crystal structure of BPSS1823, a Mip-like chaperone from Burkholderia pseudomallei | | Descriptor: | CHLORIDE ION, GLYCEROL, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE, ... | | Authors: | Norville, I.H, O'Shea, K, Sarkar-Tyson, M, Harmer, N.J. | | Deposit date: | 2011-01-28 | | Release date: | 2011-05-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (0.91 Å) | | Cite: | The Structure of a Burkholderia Pseudomallei Immunophilin-Inhibitor Complex Reveals New Approaches to Antimicrobial Development
Biochem.J., 437, 2011
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1SWS
 | | CORE-STREPTAVIDIN MUTANT D128A AT PH 4.5 | | Descriptor: | PROTEIN (STREPTAVIDIN) | | Authors: | Freitag, S, Chu, V, Le Trong, I, Klumb, L.A, To, R, Stayton, P.S, Stenkamp, R.E. | | Deposit date: | 1998-10-22 | | Release date: | 1999-07-30 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A structural snapshot of an intermediate on the streptavidin-biotin dissociation pathway.
Proc.Natl.Acad.Sci.USA, 96, 1999
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1JQZ
 | | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag. | | Descriptor: | FORMIC ACID, acidic fibroblast growth factor | | Authors: | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | | Deposit date: | 2001-08-09 | | Release date: | 2001-12-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil.
Protein Sci., 10, 2001
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3LLT
 | | Crystal structure of PF14_0431, kinase domain. | | Descriptor: | ACETATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, ... | | Authors: | Wernimont, A.K, Tempel, W, Lin, Y.H, Loppnau, P, MacKenzie, F, Sullivan, H, Weadge, J, Kozieradzki, I, Cossar, D, Sinesterra, G, Vedadi, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Hui, R, Qiu, W, Hutchinson, A, Structural Genomics Consortium (SGC) | | Deposit date: | 2010-01-29 | | Release date: | 2010-08-04 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of PF14_0431, kinase domain.
TO BE PUBLISHED
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1JT9
 | | Structure of the mutant F174A T form of the Glucosamine-6-Phosphate deaminase from E.coli | | Descriptor: | Glucosamine-6-Phosphate deaminase | | Authors: | Bustos-Jaimes, I, Sosa-Peinado, A, Rudino-Pinera, E, Horjales, E, Calcagno, M.L. | | Deposit date: | 2001-08-20 | | Release date: | 2002-02-20 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | On the role of the conformational flexibility of the active-site lid on the allosteric kinetics of glucosamine-6-phosphate deaminase.
J.Mol.Biol., 319, 2002
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2F5F
 | | Bacillus subtilis manganese transport regulator (MNTR) bound to manganese, AC conformation, pH 8.5 | | Descriptor: | MANGANESE (II) ION, Transcriptional regulator mntR | | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | | Deposit date: | 2005-11-25 | | Release date: | 2006-03-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis.
Biochemistry, 45, 2006
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2PXC
 | | Crystal structure of the Murray Valley Encephalitis Virus NS5 2'-O Methyltransferase domain in complex with SAM and GTPA | | Descriptor: | GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], S-ADENOSYLMETHIONINE | | Authors: | Assenberg, R, Ren, J, Verma, A, Walter, T.S, Alderton, D, Hurrelbrink, R.J, Fuller, S.D, Owens, R.J, Stuart, D.I, Grimes, J.M, Oxford Protein Production Facility (OPPF) | | Deposit date: | 2007-05-14 | | Release date: | 2007-05-29 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues.
J.Gen.Virol., 88, 2007
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2YBN
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5V3R
 | | CHMP4C in complex with ALIX BRO1 | | Descriptor: | Charged multivesicular body protein 4c, Programmed cell death 6-interacting protein | | Authors: | Wenzel, D.M, Alam, S.L, Sundquist, W.I. | | Deposit date: | 2017-03-08 | | Release date: | 2018-09-12 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.906 Å) | | Cite: | A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5B0E
 | | Polyketide cyclase OAC from Cannabis sativa, V59M mutant | | Descriptor: | GLYCEROL, Olivetolic acid cyclase | | Authors: | Yang, X, Matsui, T, Mori, T, Abe, I, Morita, H. | | Deposit date: | 2015-10-28 | | Release date: | 2016-01-27 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.603 Å) | | Cite: | Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa
Febs J., 283, 2016
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1MXQ
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2Q0V
 | | Crystal structure of ubiquitin conjugating enzyme E2, putative, from Plasmodium falciparum | | Descriptor: | PHOSPHATE ION, Ubiquitin-conjugating enzyme E2, putative | | Authors: | Wernimont, A.K, Lew, J, Hassanali, A, Lin, L, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Brokx, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-05-22 | | Release date: | 2007-06-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of ubiquitin conjugating enzyme E2, putative, from Plasmodium falciparum.
To be Published
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