7TRP
| Human M4 muscarinic acetylcholine receptor complex with Gi1 and the agonist iperoxo and positive allosteric modulator LY2033298 | 分子名称: | 3-amino-5-chloro-N-cyclopropyl-6-methoxy-4-methylthieno[2,3-b]pyridine-2-carboxamide, 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium, Antibody fragment scFv16, ... | 著者 | Vuckovic, Z, Mobbs, J.I, Belousoff, M.J, Glukhova, A, Sexton, P.M, Danev, R, Thal, D.M. | 登録日 | 2022-01-30 | 公開日 | 2023-05-17 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural and dynamic mechanisms of allostery at the M4 muscarinic acetylcholine receptor Elife, 2023
|
|
7TRK
| Human M4 muscarinic acetylcholine receptor complex with Gi1 and the agonist iperoxo | 分子名称: | 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium, Antibody fragment scFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Vuckovic, Z, Mobbs, J.I, Belousoff, M.J, Glukhova, A, Sexton, P.M, Danev, R, Thal, D.M. | 登録日 | 2022-01-29 | 公開日 | 2023-05-17 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural and dynamic mechanisms of allostery at the M4 muscarinic acetylcholine receptor Elife, 2023
|
|
7TRQ
| Human M4 muscarinic acetylcholine receptor complex with Gi1 and the agonist iperoxo and positive allosteric modulator VU0467154 | 分子名称: | 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium, 5-amino-3,4-dimethyl-N-{[4-(trifluoromethanesulfonyl)phenyl]methyl}thieno[2,3-c]pyridazine-6-carboxamide, Antibody fragment scFv16, ... | 著者 | Vuckovic, Z, Mobbs, J.I, Belousoff, M.J, Glukhova, A, Sexton, P.M, Danev, R, Thal, D.M. | 登録日 | 2022-01-30 | 公開日 | 2023-05-17 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural and dynamic mechanisms of allostery at the M4 muscarinic acetylcholine receptor Elife, 2023
|
|
7TRS
| Human M4 muscarinic acetylcholine receptor complex with Gi1 and the endogenous agonist acetylcholine | 分子名称: | ACETYLCHOLINE, Antibody fragment scFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Vuckovic, Z, Mobbs, J.I, Belousoff, M.J, Glukhova, A, Sexton, P.M, Danev, R, Thal, D.M. | 登録日 | 2022-01-30 | 公開日 | 2023-05-17 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural and dynamic mechanisms of allostery at the M4 muscarinic acetylcholine receptor Elife, 2023
|
|
2MG9
| Truncated EGF-A | 分子名称: | CALCIUM ION, Low-density lipoprotein receptor | 著者 | Schroeder, C.I, Rosengren, K. | 登録日 | 2013-10-30 | 公開日 | 2014-04-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Design and Synthesis of Truncated EGF-A Peptides that Restore LDL-R Recycling in the Presence of PCSK9 In Vitro. Chem.Biol., 21, 2014
|
|
1DTQ
| CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH PETT-1 (PETT131A94) | 分子名称: | HIV-1 RT A-CHAIN, HIV-1 RT B-CHAIN, N-[[3-FLUORO-4-ETHOXY-PYRID-2-YL]ETHYL]-N'-[5-NITRILOMETHYL-PYRIDYL]-THIOUREA | 著者 | Ren, J, Diprose, J, Warren, J, Esnouf, R.M, Bird, L.E, Ikemizu, S, Slater, M, Milton, J, Balzarini, J, Stuart, D.I, Stammers, D.K. | 登録日 | 2000-01-13 | 公開日 | 2000-03-20 | 最終更新日 | 2014-11-12 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses. J.Biol.Chem., 275, 2000
|
|
8AYL
| Resting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and ligand JNJ-61432059 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 5-[2-(4-fluorophenyl)-7-(4-oxidanylpiperidin-1-yl)pyrazolo[1,5-c]pyrimidin-3-yl]-1,3-dihydroindol-2-one, ... | 著者 | Zhang, D, Lape, R, Shaikh, S, Kohegyi, B, Watson, J.F, Cais, O, Nakagawa, T, Greger, I. | 登録日 | 2022-09-02 | 公開日 | 2023-04-19 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Modulatory mechanisms of TARP gamma 8-selective AMPA receptor therapeutics. Nat Commun, 14, 2023
|
|
1N9U
| Differences and Similarities in Solution Structures of Angiotensin I & II: Implication for Structure-Function Relationship | 分子名称: | Angiotensin I | 著者 | Spyroulias, G.A, Nikolakopoulou, P, Tzakos, A, Gerothanassis, I.P, Magafa, V, Manessi-Zoupa, E, Cordopatis, P. | 登録日 | 2002-11-26 | 公開日 | 2003-07-29 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Comparison of the solution structures of angiotensin I & II. Implication for structure-function relationship. Eur.J.Biochem., 270, 2003
|
|
4Y5Y
| Diabody 330 complex with EpoR | 分子名称: | Erythropoietin receptor, GLYCEROL, diabody 330 VH domain, ... | 著者 | Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C. | 登録日 | 2015-02-12 | 公開日 | 2015-03-18 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands. Cell, 160, 2015
|
|
2JB6
| Fab fragment in complex with small molecule hapten, crystal form-2 | 分子名称: | 2-{(1E,3Z,5E,7E)-7-[3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-1,3-DIHYDRO-2H-INDOL-2-YLIDENE]-4-METHYLHEPTA-1,3,5-TRIEN-1-YL}-3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-3H-INDOLIUM, FAB FRAGMENT MOR03268 HEAVY CHAIN, FAB FRAGMENT MOR03268 LIGHT CHAIN | 著者 | Hillig, R.C, Baesler, S, Malawski, G, Badock, V, Bahr, I, Schirner, M, Licha, K. | 登録日 | 2006-12-03 | 公開日 | 2008-01-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Fab Mor03268 Triggers Absorption Shift of a Diagnostic Dye Via Packaging in a Solvent-Shielded Fab Dimer Interface J.Mol.Biol., 377, 2008
|
|
7MHA
| |
1YN6
| Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a peptide from the influenza A acid polymerase | 分子名称: | 10-mer peptide from RNA-directed RNA polymerase subunit P2, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Turner, S.J, Kedzierska, K, Komodromou, H, La Gruta, N.L, Dunstone, M.A, Webb, A.I, Webby, R, Walden, H, Xie, W, McCluskey, J, Purcell, A.W, Rossjohn, J, Doherty, P.C. | 登録日 | 2005-01-23 | 公開日 | 2005-06-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations Nat.Immunol., 6, 2005
|
|
4Y5X
| Diabody 305 complex with EpoR | 分子名称: | CITRATE ANION, DI(HYDROXYETHYL)ETHER, Erythropoietin receptor, ... | 著者 | Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C. | 登録日 | 2015-02-12 | 公開日 | 2015-03-18 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands. Cell, 160, 2015
|
|
1RJZ
| Mhc Class I Natural Mutant H-2Kbm8 Heavy Chain Complexed With beta-2 Microglobulin and Herpies Simplex Virus Mutant Glycoprotein B Peptide | 分子名称: | Beta-2-microglobulin, Glycoprotein B, H-2 class I histocompatibility antigen, ... | 著者 | Miley, M.J, Messaoudi, I, Nikolich-Zugich, J, Fremont, D.H. | 登録日 | 2003-11-20 | 公開日 | 2004-12-14 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Basis for the Restoration of TCR Recognition of an MHC Allelic Variant by Peptide Secondary Anchor Substitution J.Exp.Med., 200, 2004
|
|
8AKQ
| 180 A SynPspA rod after incubation with ATP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chloroplast membrane-associated 30 kD protein | 著者 | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | 登録日 | 2022-07-31 | 公開日 | 2024-02-14 | 最終更新日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural plasticity of bacterial ESCRT-III protein PspA in higher-order assemblies. Nat.Struct.Mol.Biol., 2024
|
|
8AKS
| 215 A SynPspA rod after incubation with ATP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chloroplast membrane-associated 30 kD protein | 著者 | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | 登録日 | 2022-07-31 | 公開日 | 2024-02-14 | 最終更新日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural plasticity of bacterial ESCRT-III protein PspA in higher-order assemblies. Nat.Struct.Mol.Biol., 2024
|
|
8AKR
| 200 A SynPspA rod after incubation with ATP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chloroplast membrane-associated 30 kD protein | 著者 | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | 登録日 | 2022-07-31 | 公開日 | 2024-02-14 | 最終更新日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural plasticity of bacterial ESCRT-III protein PspA in higher-order assemblies. Nat.Struct.Mol.Biol., 2024
|
|
8AKT
| 235 A SynPspA rod after incubation with ATP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chloroplast membrane-associated 30 kD protein | 著者 | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | 登録日 | 2022-07-31 | 公開日 | 2024-02-14 | 最終更新日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural plasticity of bacterial ESCRT-III protein PspA in higher-order assemblies. Nat.Struct.Mol.Biol., 2024
|
|
6EYU
| Crystal structure of the inward H(+) pump xenorhodopsin | 分子名称: | Bacteriorhodopsin, EICOSANE, RETINAL, ... | 著者 | Kovalev, K, Shevchenko, V, Polovinkin, V, Mager, T, Gushchin, I, Melnikov, I, Borshchevskiy, V, Popov, A, Alekseev, A, Gordeliy, V. | 登録日 | 2017-11-13 | 公開日 | 2017-12-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Inward H(+) pump xenorhodopsin: Mechanism and alternative optogenetic approach. Sci Adv, 3, 2017
|
|
2J6K
| N-TERMINAL SH3 DOMAIN OF CMS (CD2AP HUMAN HOMOLOG) | 分子名称: | CD2-ASSOCIATED PROTEIN, SODIUM ION | 著者 | Moncalian, G, Cardenes, N, Deribe, Y.L, Spinola-Amilibia, M, Dikic, I, Bravo, J. | 登録日 | 2006-09-29 | 公開日 | 2006-10-11 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | Atypical Polyproline Recognition by the Cms N- Terminal SH3 Domain. J.Biol.Chem., 281, 2006
|
|
7UIT
| |
7RRH
| Crystal structure of fast switching R66M/M159T mutant of fluorescent protein Dronpa (Dronpa2) | 分子名称: | Fluorescent protein Dronpa | 著者 | Lin, C.-Y, Romei, M.G, Mathews, I.I, Boxer, S.G. | 登録日 | 2021-08-09 | 公開日 | 2021-10-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.747 Å) | 主引用文献 | Energetic Basis and Design of Enzyme Function Demonstrated Using GFP, an Excited-State Enzyme. J.Am.Chem.Soc., 144, 2022
|
|
7RRK
| Crystal structure of fast switching M159E mutant of fluorescent protein Dronpa (Dronpa2) | 分子名称: | Fluorescent protein Dronpa | 著者 | Lin, C.-Y, Romei, M.G, Mathews, I.I, Boxer, S.G. | 登録日 | 2021-08-09 | 公開日 | 2021-10-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.929 Å) | 主引用文献 | Energetic Basis and Design of Enzyme Function Demonstrated Using GFP, an Excited-State Enzyme. J.Am.Chem.Soc., 144, 2022
|
|
3FOL
| Crystal structure of the Class I MHC Molecule H-2Kwm7 with a Single Self Peptide VNDIFERI | 分子名称: | 8 residue synthetic peptide, Beta-2-microglobulin, MHC | 著者 | Brims, D.R, Qian, J, Jarchum, I, Yamada, T, Mikesh, L, Palmieri, E, Lund, T, Hattori, M, Shabanowitz, J, Hunt, D.F, Ramagopal, U.A, Malashkevich, V.N, Almo, S.C, Nathenson, S.G, DiLorenzo, T.P. | 登録日 | 2008-12-30 | 公開日 | 2010-01-12 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect Int.Immunol., 22, 2010
|
|
1ICN
| ESCHERICHIA COLI-DERIVED RAT INTESTINAL FATTY ACID BINDING PROTEIN WITH BOUND MYRISTATE AT 1.5 A RESOLUTION AND I-FABPARG106-->GLN WITH BOUND OLEATE AT 1.74 A RESOLUTION | 分子名称: | INTESTINAL FATTY ACID BINDING PROTEIN, OLEIC ACID | 著者 | Eads, J.C, Sacchettini, J.C, Kromminga, A, Gordon, J.I. | 登録日 | 1993-09-20 | 公開日 | 1994-01-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Escherichia coli-derived rat intestinal fatty acid binding protein with bound myristate at 1.5 A resolution and I-FABPArg106-->Gln with bound oleate at 1.74 A resolution. J.Biol.Chem., 268, 1993
|
|