3RAF
| Quinazolinedione-DNA cleavage complex of type IV topoisomerase from S. pneumoniae | 分子名称: | 3-amino-7-{(3R)-3-[(1S)-1-aminoethyl]pyrrolidin-1-yl}-1-cyclopropyl-6-fluoro-8-methylquinazoline-2,4(1H,3H)-dione, 5'-D(*CP*AP*TP*GP*AP*AP*T)-3', 5'-D(*CP*GP*TP*GP*CP*AP*T)-3', ... | 著者 | Laponogov, I, Pan, X.-S, Veselkov, D.A, McAuley, K.E, Fisher, L.M, Sanderson, M.R. | 登録日 | 2011-03-28 | 公開日 | 2012-03-28 | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | 主引用文献 | Inhibitor-stabilised cleavage complexes of topoisomerase IIa: structural analysis of drug-dependent inter- and intramolecular interactions To be Published
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5FBQ
| PI4KB in complex with Rab11 and the MI358 Inhibitor | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... | 著者 | Chalupska, D, Mejdrova, I, Nencka, R, Boura, E. | 登録日 | 2015-12-14 | 公開日 | 2016-12-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.789 Å) | 主引用文献 | PI4KB in complex with Rab11 and the MI358 Inhibitor To Be Published
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1TUS
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1TTZ
| X-ray structure of Northeast Structural Genomics target protein XcR50 from X. campestris | 分子名称: | conserved hypothetical protein | 著者 | Kuzin, A.P, Vorobiev, S.M, Lee, I, Acton, T.B, Ho, C.K, Cooper, B, Ma, L.-C, Xiao, R, Montelione, G, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2004-06-23 | 公開日 | 2004-07-13 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | X-ray structure of Northeast Structural Genomics target protein XcR50 from X. campestris To be Published
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1TUW
| Structural and Functional Analysis of Tetracenomycin F2 Cyclase from Streptomyces glaucescens: A Type-II Polyketide Cyclase | 分子名称: | SULFATE ION, Tetracenomycin polyketide synthesis protein tcmI | 著者 | Thompson, T.B, Katayama, K, Watanabe, K, Hutchinson, C.R, Rayment, I. | 登録日 | 2004-06-25 | 公開日 | 2004-08-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and functional analysis of tetracenomycin F2 cyclase from Streptomyces glaucescens. A type II polyketide cyclase. J.Biol.Chem., 279, 2004
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6CMP
| Closed structure of inactive SHP2 mutant C459E | 分子名称: | Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Padua, R.A.P, Sun, Y, Marko, I, Pitsawong, W, Kern, D. | 登録日 | 2018-03-06 | 公開日 | 2018-11-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2. Nat Commun, 9, 2018
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6GS3
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4ALY
| Borrelia burgdorferi outer surface lipoprotein BBA64 | 分子名称: | P35 ANTIGEN, SULFATE ION | 著者 | Brangulis, K, Tars, K, Petrovskis, I, Kazaks, A, Ranka, R, Baumanis, V. | 登録日 | 2012-03-06 | 公開日 | 2013-04-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of an Outer Surface Lipoprotein Bba64 from the Lyme Disease Agent Borrelia Burgdorferi which is Critical to Ensure Infection After a Tick Bite Acta Crystallogr.,Sect.D, 69, 2013
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5FJ5
| Structure of the in vitro assembled bacteriophage phi6 polymerase complex | 分子名称: | MAJOR INNER PROTEIN P1 | 著者 | Ilca, S, Kotecha, A, Sun, X, Poranen, M.P, Stuart, D.I, Huiskonen, J.T. | 登録日 | 2015-10-06 | 公開日 | 2015-11-04 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Localized Reconstruction of Subunits from Electron Cryomicroscopy Images of Macromolecular Complexes. Nat.Commun., 6, 2015
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7X1K
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5FKZ
| Structure of E.coli Constitutive lysine decarboxylase | 分子名称: | LYSINE DECARBOXYLASE, CONSTITUTIVE | 著者 | Kandiah, E, Carriel, D, Perard, J, Malet, H, Bacia, M, Liu, K, Chan, S.W.S, Houry, W.A, Ollagnier de Choudens, S, Elsen, S, Gutsche, I. | 登録日 | 2015-10-20 | 公開日 | 2016-09-21 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | 主引用文献 | Structural Insights Into the Escherichia Coli Lysine Decarboxylases and Molecular Determinants of Interaction with the Aaa+ ATPase Rava. Sci.Rep., 6, 2016
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5FOJ
| Cryo electron microscopy structure of Grapevine Fanleaf Virus complex with Nanobody | 分子名称: | Nanobody, RNA2 polyprotein | 著者 | Orlov, I, Hemmer, C, Ackerer, L, Lorber, B, Ghannam, A, Poignavent, V, Hleibieh, K, Sauter, C, Schmitt-Keichinger, C, Belval, L, Hily, J.M, Marmonier, A, Komar, V, Gersch, S, Schellenberger, P, Bron, P, Vigne, E, Muyldermans, S, Lemaire, O, Demangeat, G, Ritzenthaler, C, Klaholz, B.P. | 登録日 | 2015-11-22 | 公開日 | 2016-01-20 | 最終更新日 | 2021-08-11 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis of nanobody recognition of grapevine fanleaf virus and of virus resistance loss. Proc.Natl.Acad.Sci.USA, 2020
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2WXF
| The crystal structure of the murine class IA PI 3-kinase p110delta in complex with PIK-39. | 分子名称: | 2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM | 著者 | Berndt, A, Miller, S, Williams, O, Lee, D.D, Houseman, B.T, Pacold, J.I, Gorrec, F, Hon, W.-C, Liu, Y, Rommel, C, Gaillard, P, Ruckle, T, Schwarz, M.K, Shokat, K.M, Shaw, J.P, Williams, R.L. | 登録日 | 2009-11-09 | 公開日 | 2010-01-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The P110D Structure: Mechanisms for Selectivity and Potency of New Pi(3)K Inhibitors Nat.Chem.Biol., 6, 2010
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5FPS
| Structure of hepatitis C virus (HCV) full-length NS3 complex with small-molecule ligand 3-aminobenzene-1,2-dicarboxylic acid (AT1246) in an alternate binding site. | 分子名称: | 3-AMINOBENZENE-1,2-DICARBOXYLIC ACID, HEPATITIS C VIRUS FULL-LENGTH NS3 COMPLEX | 著者 | Jhoti, H, Ludlow, R.F, Saini, H.K, Tickle, I.J, Verdonk, M, Williams, P.A. | 登録日 | 2015-12-02 | 公開日 | 2015-12-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Detection of Secondary Binding Sites in Proteins Using Fragment Screening. Proc.Natl.Acad.Sci.USA, 112, 2015
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2WXO
| The crystal structure of the murine class IA PI 3-kinase p110delta in complex with AS5. | 分子名称: | N-(3-{[(1Z)-3,5-DIMETHOXYCYCLOHEXA-2,4-DIEN-1-YLIDENE]AMINO}QUINOXALIN-2-YL)-4-FLUOROBENZENESULFONAMIDE, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM | 著者 | Berndt, A, Miller, S, Williams, O, Lee, D.D, Houseman, B.T, Pacold, J.I, Gorrec, F, Hon, W.-C, Liu, Y, Rommel, C, Gaillard, P, Ruckle, T, Schwarz, M.K, Shokat, K.M, Shaw, J.P, Williams, R.L. | 登録日 | 2009-11-09 | 公開日 | 2010-01-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | The P110D Structure: Mechanisms for Selectivity and Potency of New Pi(3)K Inhibitors Nat.Chem.Biol., 6, 2010
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1UAC
| Crystal Structure of HYHEL-10 FV MUTANT SFSF Complexed with TURKEY WHITE LYSOZYME | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | 著者 | Kumagai, I, Nishimiya, Y, Kondo, H, Tsumoto, K. | 登録日 | 2003-03-08 | 公開日 | 2004-03-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural consequences of target epitope-directed functional alteration of an antibody. The case of anti-hen lysozyme antibody, HyHEL-10 J.BIOL.CHEM., 278, 2003
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5FR0
| The details of glycolipid glycan hydrolysis by the structural analysis of a family 123 glycoside hydrolase from Clostridium perfringens | 分子名称: | 2-deoxy-2-[(difluoroacetyl)amino]-beta-D-galactopyranose, BETA-N-ACETYLGALACTOSAMINIDASE, PHOSPHATE ION | 著者 | Noach, I, Pluvinage, B, Laurie, C, Abe, K.T, Alteen, M, Vocadlo, D.J, Boraston, A.B. | 登録日 | 2015-12-14 | 公開日 | 2016-03-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | The Details of Glycolipid Glycan Hydrolysis by the Structural Analysis of a Family 123 Glycoside Hydrolase from Clostridium Perfringens J.Mol.Biol., 428, 2016
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5FQG
| The details of glycolipid glycan hydrolysis by the structural analysis of a family 123 glycoside hydrolase from Clostridium perfringens | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-beta-D-galactopyranose, BETA-N-ACETYLGALACTOSAMINIDASE, FORMIC ACID | 著者 | Noach, I, Pluvinage, B, Laurie, C, Abe, K.T, Alteen, M, Vocadlo, D.J, Boraston, A.B. | 登録日 | 2015-12-10 | 公開日 | 2016-03-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Details of Glycolipid Glycan Hydrolysis by the Structural Analysis of a Family 123 Glycoside Hydrolase from Clostridium Perfringens J.Mol.Biol., 428, 2016
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1UAK
| Crystal structure of tRNA(m1G37)methyltransferase: Insight into tRNA recognition | 分子名称: | S-ADENOSYLMETHIONINE, tRNA (Guanine-N(1)-)-methyltransferase | 著者 | Ahn, H.J, Kim, H.-W, Yoon, H.-J, Lee, B.I, Suh, S.W, Yang, J.K. | 登録日 | 2003-03-11 | 公開日 | 2003-06-17 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of tRNA(m(1)G37)methyltransferase: insights into tRNA recognition EMBO J., 22, 2003
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1UCA
| Crystal structure of the Ribonuclease MC1 from bitter gourd seeds complexed with 2'-UMP | 分子名称: | PHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER, Ribonuclease MC | 著者 | Suzuki, A, Yao, M, Tanaka, I, Numata, T, Kikukawa, S, Yamasaki, N, Kimura, M. | 登録日 | 2003-04-10 | 公開日 | 2003-04-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Crystal structures of the ribonuclease MC1 from bitter gourd seeds, complexed with 2'-UMP or 3'-UMP, reveal structural basis for uridine specificity Biochem.Biophys.Res.Commun., 275, 2000
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7X9R
| Crystal structure of the antirepressor GmaR | 分子名称: | Glycosyl transferase family 2 | 著者 | Cho, S.Y, Na, H.W, Oh, H.B, Kwak, Y.M, Song, W.S, Park, S.C, Yoon, S.I. | 登録日 | 2022-03-16 | 公開日 | 2022-11-09 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural basis of flagellar motility regulation by the MogR repressor and the GmaR antirepressor in Listeria monocytogenes. Nucleic Acids Res., 50, 2022
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3ES6
| Crystal structure of the novel complex formed between Zinc 2-glycoprotein (ZAG) and Prolactin inducible protein (PIP) from human seminal plasma | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, HEXAETHYLENE GLYCOL, ... | 著者 | Hassan, M.I, Bilgrami, S, Kumar, V, Singh, N, Yadav, S, Kaur, P, Singh, T.P. | 登録日 | 2008-10-04 | 公開日 | 2008-10-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.23 Å) | 主引用文献 | Crystal structure of the novel complex formed between zinc alpha2-glycoprotein (ZAG) and prolactin-inducible protein (PIP) from human seminal plasma J.Mol.Biol., 384, 2008
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5HJ1
| Crystal structure of PDZ domain of pullulanase C protein of type II secretion system from Klebsiella pneumoniae in complex with fatty acid | 分子名称: | Pullulanase C protein, VACCENIC ACID | 著者 | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-01-12 | 公開日 | 2016-02-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of PDZ domain of pullulanase C protein of type II secretion system from Klebsiella pneumoniae in complex with fatty acid To Be Published
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4A66
| Mutations in the neighbourhood of CotA-laccase trinuclear site: D116A mutant | 分子名称: | 1,2-ETHANEDIOL, COPPER (II) ION, PEROXIDE ION, ... | 著者 | Silva, C.S, Lindley, P.F, Bento, I. | 登録日 | 2011-10-31 | 公開日 | 2012-01-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The Role of Asp116 in the Reductive Cleavage of Dioxygen to Water in Cota Laccase: Assistance During the Proton Transfer Mechanism Acta Crystallogr.,Sect.D, 68, 2012
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1TVZ
| Crystal structure of 3-hydroxy-3-methylglutaryl-coenzyme A synthase from Staphylococcus aureus | 分子名称: | 3-hydroxy-3-methylglutaryl-CoA synthase, SULFATE ION | 著者 | Campobasso, N, Patel, M, Wilding, I.E, Kallender, H, Rosenberg, M, Gwynn, M. | 登録日 | 2004-06-30 | 公開日 | 2004-08-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase: crystal structure and mechanism J.Biol.Chem., 279, 2004
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