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PDB: 17822 件

6R66
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Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue
分子名称: 1-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]cyclopropane-1-carboxylic acid, Transthyretin
著者Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G.
登録日2019-03-26
公開日2019-09-11
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
4G32
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Crystal Structure of a Phospholipid-Lipoxygenase Complex from Pseudomonas aeruginosa at 1.75A (P21212)
分子名称: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradec-5-enoyloxy)propyl (11Z)-octadec-11-enoate, 15S-LIPOXYGENASE, FE (II) ION, ...
著者Carpena, X, Garreta, A, Val-Moraes, S.P, Garcia-Fernandez, Q, Fita, I.
登録日2012-07-13
公開日2013-11-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure and interaction with phospholipids of a prokaryotic lipoxygenase from Pseudomonas aeruginosa.
Faseb J., 27, 2013
5ULC
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BU of 5ulc by Molmil
PLASMODIUM FALCIPARUM BROMODOMAIN-CONTAINING PROTEIN PF10_0328
分子名称: Bromodomain protein 1
著者Wernimont, A.K, Amaya, M.F, Lam, A, Ali, A, Zhang, A.Z, Kenzina, L, Lin, Y.H, MacKenzie, F, Kozieradzki, I, Cossar, D, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Weigelt, J, Hui, R, Walker, J.R, Qiu, W, Brand, V, Structural Genomics Consortium (SGC)
登録日2017-01-24
公開日2017-02-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献PLASMODIUM FALCIPARUM BROMODOMAIN-CONTAINING PROTEIN PF10_0328
To be published
3BZO
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BU of 3bzo by Molmil
Crystal structural of native EscU C-terminal domain
分子名称: EscU, SULFATE ION
著者Zarivach, R, Deng, W, Vuckovic, M, Felise, H.B, Nguyen, H.V, Miller, S.I, Finlay, B.B, Strynadka, N.C.J.
登録日2008-01-18
公開日2008-04-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
3BZV
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BU of 3bzv by Molmil
Crystal structural of the mutated T264A EscU C-terminal domain
分子名称: EscU
著者Zarivach, R, Deng, W, Vuckovic, M, Felise, H.B, Nguyen, H.V, Miller, S.I, Finlay, B.B, Strynadka, N.C.J.
登録日2008-01-18
公開日2008-04-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
6JFG
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BU of 6jfg by Molmil
K1U bound crystal structure of class II peptide deformylase from methicillin resistant Staphylococcus aureus
分子名称: (3R)-3-benzyl-4-oxo-4-[(2-oxo-2-phenylethyl)sulfanyl]butanoic acid, NICKEL (II) ION, Peptide deformylase
著者Lee, I.H, Ho, T.H, Kang, L.W.
登録日2019-02-08
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献K1U bound crystal structure of class II peptide deformylase from methicillin resistant Staphylococcus aureus
To be published
4GY7
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Crystallographic structure analysis of urease from Jack bean (Canavalia ensiformis) at 1.49 A Resolution
分子名称: 1,2-ETHANEDIOL, ACETONE, BETA-MERCAPTOETHANOL, ...
著者Begum, A, Banumathi, S, Choudhary, M.I, Betzel, C.
登録日2012-09-05
公開日2012-11-07
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.492 Å)
主引用文献Crystallographic structure analysis of urease from Jack bean (Canavalia ensiformis) at 1.49 A Resolution
To be Published
4YZK
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BU of 4yzk by Molmil
Crystal structure of the indole prenyltransferase TleC apo structure
分子名称: Tryptophan dimethylallyltransferase
著者Mori, T, Morita, H, Abe, I.
登録日2015-03-25
公開日2016-03-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Manipulation of prenylation reactions by structure-based engineering of bacterial indolactam prenyltransferases.
Nat Commun, 7, 2016
5JX1
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BU of 5jx1 by Molmil
The neck-linker and alpha 7 helix of Mus musculus KIF3A fused to EB1
分子名称: Chimera protein of Kinesin-like protein KIF3A and Microtubule-associated protein RP/EB family member 1
著者Phillips, R.K, Rayment, I.
登録日2016-05-12
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil.
J.Biol.Chem., 291, 2016
6JEX
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K4U bound crystal peptide deformylase from Acinetobacter baumanii
分子名称: L-[(N-HYDROXYAMINO)CARBONYL]PHENYLALANINE, Peptide deformylase, ZINC ION
著者Lee, I.H, Ho, T.H, Kang, L.W.
登録日2019-02-07
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献K4U bound crystal peptide deformylase from Acinetobacter baumanii
To be published
4HFU
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BU of 4hfu by Molmil
Crystal structure of Fab 8M2 in complex with a H2N2 influenza virus hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 8M2 heavy chain, Fab 8M2 light chain, ...
著者Xu, R, Wilson, I.A.
登録日2012-10-05
公開日2013-02-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.106 Å)
主引用文献A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin.
Nat.Struct.Mol.Biol., 20, 2013
6JK7
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BU of 6jk7 by Molmil
Crystal structure of SpaE basal pilin from Lactobacillus rhamnosus GG - Trigonal form
分子名称: Pilus assembly protein
著者Megta, A.K, Mishra, A.K, Palva, A, von Ossowski, I, Krishnan, V.
登録日2019-02-27
公開日2019-06-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.204 Å)
主引用文献Crystal structure of basal pilin SpaE reveals the molecular basis of its incorporation in the lactobacillar SpaFED pilus.
J.Struct.Biol., 207, 2019
6T39
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BU of 6t39 by Molmil
Crystal structure of rsEGFP2 in its off-state determined by SFX
分子名称: Green fluorescent protein
著者Woodhouse, J, Coquelle, N, Adam, V, Barends, T.R.M, De La Mora, E, Bourgeois, D, Colletier, J.P, Schlichting, I, Weik, M.
登録日2019-10-10
公開日2020-02-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Photoswitching mechanism of a fluorescent protein revealed by time-resolved crystallography and transient absorption spectroscopy.
Nat Commun, 11, 2020
5K87
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BU of 5k87 by Molmil
crystal structure of malonate bound to methylaconitate isomerase PrpF from Shewanella oneidensis
分子名称: 2-methyl-aconitate isomerase, MALONATE ION
著者Rayment, I, Wetterhorn, K.
登録日2016-05-27
公開日2017-05-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.219 Å)
主引用文献The PrpF protein of Shewanella oneidensis MR-1 catalyzes the isomerization of 2-methyl-cis-aconitate during the catabolism of propionate via the AcnD-dependent 2-methylcitric acid cycle.
PLoS ONE, 12, 2017
4EB1
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BU of 4eb1 by Molmil
Hyperstable in-frame insertion variant of antithrombin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III
著者Martinez-Martinez, I, Johnson, D.J.D, Yamasaki, M, Corral, J, Huntington, J.A.
登録日2012-03-23
公開日2012-07-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Type II antithrombin deficiency caused by a large in-frame insertion: structural, functional and pathological relevance.
J.Thromb.Haemost., 10, 2012
5U04
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BU of 5u04 by Molmil
Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase
分子名称: PHOSPHATE ION, ZINC ION, Zika Virus NS5 RdRp
著者Godoy, A.S, Lima, G.M.A, Oliveira, K.I.Z, Torres, N.U, Maluf, F.V, Guido, R.V.C, Oliva, G.
登録日2016-11-22
公開日2017-02-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase.
Nat Commun, 8, 2017
4GXR
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BU of 4gxr by Molmil
Structure of ATP bound RpMatB-BxBclM chimera B3
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CARBONATE ION, GLYCEROL, ...
著者Rank, K.C, Crosby, H.A, Escalante-Semerena, J.C, Rayment, I.
登録日2012-09-04
公開日2012-10-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights into the Substrate Specificity of the Rhodopseudomonas palustris Protein Acetyltransferase RpPat: IDENTIFICATION OF A LOOP CRITICAL FOR RECOGNITION BY RpPat.
J.Biol.Chem., 287, 2012
4EW2
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BU of 4ew2 by Molmil
The structure of human glycinamide ribonucleotide transformylase in complex with 10S-methylthio-DDATHF.
分子名称: N-({4-[(1S)-4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-(methylsulfanyl)butyl]phenyl}carbonyl)-L-glutamic acid, PHOSPHATE ION, SULFATE ION, ...
著者Connelly, S, DeMartino, K, Boger, D.L, Wilson, I.A.
登録日2012-04-26
公開日2013-07-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.602 Å)
主引用文献Biological and Structural Evaluation of 10R- and 10S-Methylthio-DDACTHF Reveals a New Role for Sulfur in Inhibition of Glycinamide Ribonucleotide Transformylase.
Biochemistry, 52, 2013
4HDP
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BU of 4hdp by Molmil
Crystal Structure of HIV-1 protease mutants I50V complexed with inhibitor GRL-0519
分子名称: (3R,3aS,3bR,6aS,7aS)-octahydrodifuro[2,3-b:3',2'-d]furan-3-yl [(1S,2R)-1-benzyl-2-hydroxy-3-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}propyl]carbamate, CHLORIDE ION, HIV-1 Protease, ...
著者Shen, C.H, Zhang, H, Weber, I.T.
登録日2012-10-02
公開日2013-08-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Novel P2 tris-tetrahydrofuran group in antiviral compound 1 (GRL-0519) fills the S2 binding pocket of selected mutants of HIV-1 protease.
J.Med.Chem., 56, 2013
4IFF
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BU of 4iff by Molmil
Structural organization of FtsB, a transmembrane protein of the bacterial divisome
分子名称: Fusion of phage phi29 Gp7 protein and Cell division protein FtsB, GLYCEROL
著者LaPointe, L.M, Taylor, K.C, Subramaniam, S, Khadria, A, Rayment, I, Senes, A.
登録日2012-12-14
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Organization of FtsB, a Transmembrane Protein of the Bacterial Divisome.
Biochemistry, 52, 2013
5KHG
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BU of 5khg by Molmil
HCN2 CNBD in complex with cytidine-3', 5'-cyclic monophosphate (cCMP)
分子名称: 4-amino-1-[(2S,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]pyrimidin-2(1H)-one, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
著者Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A.
登録日2016-06-14
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.241 Å)
主引用文献Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening.
Structure, 24, 2016
3BER
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BU of 3ber by Molmil
Human DEAD-box RNA-helicase DDX47, conserved domain I in complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, Probable ATP-dependent RNA helicase DDX47, ...
著者Karlberg, T, Busam, R.D, Arrowsmith, C.H, Berglund, H, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kallas, A, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日2007-11-20
公開日2007-12-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5, 2010
3BF6
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BU of 3bf6 by Molmil
Thrombin:suramin complex
分子名称: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID, PHE-PRO-ARG, Thrombin, ...
著者Lima, L.M.T.R, Polikarpov, I, Monteiro, R.Q.
登録日2007-11-20
公開日2007-12-25
最終更新日2015-07-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and thermodynamic analysis of thrombin:suramin interaction in solution and crystal phases.
Biochim.Biophys.Acta, 1794, 2009
6H5Q
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BU of 6h5q by Molmil
Cryo-EM structure of in vitro assembled Measles virus N into nucleocapsid-like particles (NCLPs) bound to polyA RNA hexamers.
分子名称: Nucleocapsid, RNA (5'-R(*AP*AP*AP*AP*AP*A)-3')
著者Desfosses, A, Milles, S, Ringkjobing Jensen, M, Guseva, S, Colletier, J, Maurin, D, Schoehn, G, Gutsche, I, Ruigrok, R, Blackledge, M.
登録日2018-07-25
公開日2019-03-13
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Assembly and cryo-EM structures of RNA-specific measles virus nucleocapsids provide mechanistic insight into paramyxoviral replication.
Proc.Natl.Acad.Sci.USA, 116, 2019
6MOT
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BU of 6mot by Molmil
Bacteroides intestinalis feruloyl esterase, Bacint_01033
分子名称: 1,2-ETHANEDIOL, Isoamylase N-terminal domain protein
著者Koropatkin, N.M, Pereira, G.V, Cann, I.
登録日2018-10-04
公開日2019-10-16
最終更新日2021-01-27
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Degradation of complex arabinoxylans by human colonic Bacteroidetes
Nat Commun, 2021

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