3BF6
Thrombin:suramin complex
Summary for 3BF6
Entry DOI | 10.2210/pdb3bf6/pdb |
Related | 1PPB 2H9T |
Descriptor | Thrombin, LIGHT CHAIN, Thrombin, HEAVY CHAIN, PHE-PRO-ARG, ... (5 entities in total) |
Functional Keywords | thrombin, suramin, blood, coagulation, acute phase, blood coagulation, cleavage on pair of basic residues, disease mutation, gamma-carboxyglutamic acid, glycoprotein, hydrolase, kringle, protease, secreted, serine protease, zymogen |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 |
Total number of polymer chains | 3 |
Total formula weight | 35593.53 |
Authors | Lima, L.M.T.R.,Polikarpov, I.,Monteiro, R.Q. (deposition date: 2007-11-20, release date: 2007-12-25, Last modification date: 2015-07-15) |
Primary citation | Lima, L.M.,Becker, C.F.,Giesel, G.M.,Marques, A.F.,Cargnelutti, M.T.,de Oliveira Neto, M.,Queiroz Monteiro, R.,Verli, H.,Polikarpov, I. Structural and thermodynamic analysis of thrombin:suramin interaction in solution and crystal phases. Biochim.Biophys.Acta, 1794:873-881, 2009 Cited by PubMed: 19332154DOI: 10.1016/j.bbapap.2009.03.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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