1W3X
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![BU of 1w3x by Molmil](/molmil-images/mine/1w3x) | Isopenicillin N synthase d-(L-a-aminoadipoyl)-(3R)-methyl-L-cysteine D-a-hydroxyisovaleryl ester complex (Oxygen exposed 5 minutes 20 bar) | Descriptor: | FE (II) ION, ISOPENICILLIN N SYNTHETASE, N~6~-[(1R)-1-({[(1R,2R)-1-CARBOXY-3-HYDROXY-2-METHYLPROPYL]OXY}CARBONYL)-2-MERCAPTOPROP-2-EN-1-YL]-6-OXO-L-LYSINE | Authors: | Daruzzaman, A, Clifton, I.J, Rutledge, P.J. | Deposit date: | 2004-07-20 | Release date: | 2005-12-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Unexpected Oxidation of a Depsipeptide Substrate Analogue in Crystalline Isopenicillin N Synthase. Chembiochem, 7, 2006
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3JVW
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![BU of 3jvw by Molmil](/molmil-images/mine/3jvw) | HIV-1 Protease Mutant G86A with symmetric inhibitor DMP323 | Descriptor: | Gag-Pol polyprotein, [4-R-(-4-ALPHA,5-ALPHA,6-BETA,7-BETA)]-HEXAHYDRO-5,6-BIS(HYDROXY)-[1,3-BIS([4-HYDROXYMETHYL-PHENYL]METHYL)-4,7-BIS(PHEN YLMETHYL)]-2H-1,3-DIAZEPINONE | Authors: | Tie, Y, Weber, I.T. | Deposit date: | 2009-09-17 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Highly conserved glycine 86 and arginine 87 residues contribute differently to the structure and activity of the mature HIV-1 protease Proteins, 78, 2009
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3JW2
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![BU of 3jw2 by Molmil](/molmil-images/mine/3jw2) | HIV-1 Protease Mutant G86S with DARUNAVIR | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, Gag-Pol polyprotein, ... | Authors: | Tie, Y, Weber, I.T. | Deposit date: | 2009-09-17 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Highly conserved glycine 86 and arginine 87 residues contribute differently to the structure and activity of the mature HIV-1 protease Proteins, 78, 2009
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1KMG
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![BU of 1kmg by Molmil](/molmil-images/mine/1kmg) | The Solution Structure Of Monomeric Copper-free Superoxide Dismutase | Descriptor: | Superoxide Dismutase, ZINC ION | Authors: | Banci, L, Bertini, I, Cantini, F, D'Onofrio, M, Viezzoli, M.S. | Deposit date: | 2001-12-15 | Release date: | 2002-10-02 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Structure and dynamics of copper-free SOD: The protein before binding copper. Protein Sci., 11, 2002
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1KPP
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![BU of 1kpp by Molmil](/molmil-images/mine/1kpp) | Structure of the Tsg101 UEV domain | Descriptor: | Tumor susceptibility gene 101 protein | Authors: | Pornillos, O, Alam, S.L, Rich, R.L, Myszka, D.G, Davis, D.R, Sundquist, W.I. | Deposit date: | 2002-01-02 | Release date: | 2002-05-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure and functional interactions of the Tsg101 UEV domain. EMBO J., 21, 2002
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1PBI
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![BU of 1pbi by Molmil](/molmil-images/mine/1pbi) | |
1W04
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![BU of 1w04 by Molmil](/molmil-images/mine/1w04) | Isopenicillin N Synthase Aminoadipoyl-Cysteinyl-Glycine-Fe-NO Complex | Descriptor: | DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-GLYCINE, FE (II) ION, HYDROXYAMINE, ... | Authors: | Long, A.J, Clifton, I.J, Rutledge, P.J. | Deposit date: | 2004-06-01 | Release date: | 2005-05-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Structural Studies on the Reaction of Isopenicillin N Synthase with the Truncated Substrate Analogues Delta-(L-Alpha-Aminoadipoyl)-L-Cysteinyl-Glycine and Delta-(L-Alpha-Aminoadipoyl)-L-Cysteinyl-D- Alanine Biochemistry, 44, 2005
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1KV8
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![BU of 1kv8 by Molmil](/molmil-images/mine/1kv8) | Crystal Structure of 3-Keto-L-Gulonate 6-Phosphate Decarboxylase | Descriptor: | 3-Keto-L-Gulonate 6-Phosphate Decarboxylase, MAGNESIUM ION, PHOSPHATE ION | Authors: | Wise, E, Yew, W.S, Babbitt, P.C, Gerlt, J.A, Rayment, I. | Deposit date: | 2002-01-25 | Release date: | 2002-04-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Homologous (beta/alpha)8-barrel enzymes that catalyze unrelated reactions: orotidine 5'-monophosphate decarboxylase and 3-keto-L-gulonate 6-phosphate decarboxylase. Biochemistry, 41, 2002
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7JMO
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![BU of 7jmo by Molmil](/molmil-images/mine/7jmo) | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody COVA2-04 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA2-04 heavy chain, COVA2-04 light chain, ... | Authors: | Wu, N.C, Yuan, M, Liu, H, Zhu, X, Wilson, I.A. | Deposit date: | 2020-08-02 | Release date: | 2020-08-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.359 Å) | Cite: | An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain. Cell Rep, 33, 2020
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1KDQ
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![BU of 1kdq by Molmil](/molmil-images/mine/1kdq) | Crystal Structure Analysis of the Mutant S189D Rat Chymotrypsin | Descriptor: | CALCIUM ION, CHYMOTRYPSIN B, B CHAIN, ... | Authors: | Szabo, E, Bocskei, Z, Naray-Szabo, G, Graf, L, Venekei, I. | Deposit date: | 2001-11-13 | Release date: | 2003-06-10 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Three Dimensional Structures of S189D Chymotrypsin and D189S Trypsin Mutants: The Effect of Polarity at Site 189 on a Protease-specific Stabilization of
the Substrate-binding Site J.Mol.Biol., 331, 2003
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7JRQ
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![BU of 7jrq by Molmil](/molmil-images/mine/7jrq) | Crystallographically Characterized De Novo Designed Mn-Diphenylporphyrin Binding Protein | Descriptor: | CHLORIDE ION, GLYCEROL, MPP1, ... | Authors: | Mann, S.I, DeGrado, W.F. | Deposit date: | 2020-08-12 | Release date: | 2021-01-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | De Novo Design, Solution Characterization, and Crystallographic Structure of an Abiological Mn-Porphyrin-Binding Protein Capable of Stabilizing a Mn(V) Species. J.Am.Chem.Soc., 143, 2021
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3K21
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![BU of 3k21 by Molmil](/molmil-images/mine/3k21) | Crystal Structure of carboxy-terminus of PFC0420w. | Descriptor: | ACETATE ION, CALCIUM ION, Calcium-dependent protein kinase 3, ... | Authors: | Wernimont, A.K, Hutchinson, A, Artz, J.D, Mackenzie, F, Cossar, D, Kozieradzki, I, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Hui, R, Amani, M, Structural Genomics Consortium (SGC) | Deposit date: | 2009-09-29 | Release date: | 2010-01-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Structures of parasitic CDPK domains point to a common mechanism of activation. Proteins, 79, 2011
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1KFJ
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![BU of 1kfj by Molmil](/molmil-images/mine/1kfj) | CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH L-SERINE | Descriptor: | SODIUM ION, TRYPTOPHAN SYNTHASE ALPHA CHAIN, TRYPTOPHAN SYNTHASE BETA CHAIN, ... | Authors: | Kulik, V, Weyand, M, Seidel, R, Niks, D, Arac, D, Dunn, M.F, Schlichting, I. | Deposit date: | 2001-11-21 | Release date: | 2003-10-21 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | On the role of alphaThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase. J.Mol.Biol., 324, 2002
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7JUG
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![BU of 7jug by Molmil](/molmil-images/mine/7jug) | |
7JW3
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![BU of 7jw3 by Molmil](/molmil-images/mine/7jw3) | Crystal structure of Aedes aegypti Nibbler NTD domain | Descriptor: | Exonuclease mut-7 homolog | Authors: | Xie, W, Sowemimo, I, Hayashi, R, Wang, J, Brennecke, J, Ameres, S.L, Patel, D.J. | Deposit date: | 2020-08-24 | Release date: | 2021-01-20 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structure-function analysis of microRNA 3'-end trimming by Nibbler. Proc.Natl.Acad.Sci.USA, 117, 2020
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1KDX
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![BU of 1kdx by Molmil](/molmil-images/mine/1kdx) | KIX DOMAIN OF MOUSE CBP (CREB BINDING PROTEIN) IN COMPLEX WITH PHOSPHORYLATED KINASE INDUCIBLE DOMAIN (PKID) OF RAT CREB (CYCLIC AMP RESPONSE ELEMENT BINDING PROTEIN), NMR 17 STRUCTURES | Descriptor: | CBP, CREB | Authors: | Radhakrishnan, I, Perez-Alvarado, G.C, Dyson, H.J, Wright, P.E. | Deposit date: | 1997-09-16 | Release date: | 1998-11-25 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | Solution structure of the KIX domain of CBP bound to the transactivation domain of CREB: a model for activator:coactivator interactions. Cell(Cambridge,Mass.), 91, 1997
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1YOK
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![BU of 1yok by Molmil](/molmil-images/mine/1yok) | crystal structure of human LRH-1 bound with TIF-2 peptide and phosphatidylglycerol | Descriptor: | (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, Nuclear receptor coactivator 2, Orphan nuclear receptor NR5A2 | Authors: | Krylova, I.N, Sablin, E.P, Moore, J, Xu, R.X, Waitt, G.M, MacKay, J.A, Juzumiene, D, Bynum, J.M, Madauss, K, Montana, V, Lebedeva, L, Suzawa, M, Williams, J.D, Williams, S.P, Guy, R.K, Thornton, J.W, Fletterick, R.J, Willson, T.M, Ingraham, H.A. | Deposit date: | 2005-01-27 | Release date: | 2005-07-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1. Cell(Cambridge,Mass.), 120, 2005
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1KFK
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![BU of 1kfk by Molmil](/molmil-images/mine/1kfk) | Crystal structure of Tryptophan Synthase From Salmonella Typhimurium | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE ALPHA CHAIN, ... | Authors: | Kulik, V, Weyand, M, Seidel, R, Niks, D, Arac, D, Dunn, M.F, Schlichting, I. | Deposit date: | 2001-11-21 | Release date: | 2003-10-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | On the role of alphaThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase. J.Mol.Biol., 324, 2002
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1YUO
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![BU of 1yuo by Molmil](/molmil-images/mine/1yuo) | Optimisation of the surface electrostatics as a strategy for cold adaptation of uracil-DNA N-glycosylase (UNG)from atlantic cod (Gadus morhua) | Descriptor: | Uracil-DNA glycosylase | Authors: | Moe, E, Leiros, I, Riise, E.K, Olufsen, M, Lanes, O, Smalas, A.O, Willassen, N.P. | Deposit date: | 2005-02-14 | Release date: | 2005-03-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Optimisation of the surface electrostatics as a strategy for cold adaptation of uracil-DNA N-glycosylase (UNG) from Atlantic cod (Gadus morhua) J.Mol.Biol., 343, 2004
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1YMR
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![BU of 1ymr by Molmil](/molmil-images/mine/1ymr) | The study of reductive unfolding pathways of RNase A (Y92A mutant) | Descriptor: | Ribonuclease pancreatic | Authors: | Xu, G, Narayan, M, Kurinov, I, Ripoll, D.R, Welker, E, Khalili, M, Ealick, S.E, Scheraga, H.A. | Deposit date: | 2005-01-21 | Release date: | 2006-01-31 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A localized specific interaction alters the unfolding pathways of structural homologues. J.Am.Chem.Soc., 128, 2006
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1PK5
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![BU of 1pk5 by Molmil](/molmil-images/mine/1pk5) | |
7JUH
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![BU of 7juh by Molmil](/molmil-images/mine/7juh) | |
1YUR
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![BU of 1yur by Molmil](/molmil-images/mine/1yur) | Solution structure of apo-S100A13 (minimized mean structure) | Descriptor: | S100 calcium-binding protein A13 | Authors: | Arnesano, F, Banci, L, Bertini, I, Fantoni, A, Tenori, L, Viezzoli, M.S, Structural Proteomics in Europe (SPINE) | Deposit date: | 2005-02-14 | Release date: | 2005-10-18 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural Interplay between Calcium(II) and Copper(II) Binding to S100A13 Protein Angew.Chem.Int.Ed.Engl., 44, 2005
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1YRC
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![BU of 1yrc by Molmil](/molmil-images/mine/1yrc) | X-ray Crystal Structure of hydrogenated Cytochrome P450cam | Descriptor: | CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... | Authors: | Meilleur, F, Dauvergne, M.-T, Schlichting, I, Myles, D.A.A. | Deposit date: | 2005-02-03 | Release date: | 2005-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Production and X-ray crystallographic analysis of fully deuterated cytochrome P450cam. Acta Crystallogr.,Sect.D, 61, 2005
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3KJ6
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![BU of 3kj6 by Molmil](/molmil-images/mine/3kj6) | Crystal structure of a Methylated beta2 Adrenergic Receptor-Fab complex | Descriptor: | Beta-2 adrenergic receptor, Fab heavy chain, Fab light chain, ... | Authors: | Bokoch, M.P, Zou, Y, Rasmussen, S.G.F, Liu, C.W, Nygaard, R, Rosenbaum, D.M, Fung, J.J, Choi, H.-J, Thian, F.S, Kobilka, T.S, Puglisi, J.D, Weis, W.I, Pardo, L, Prosser, S, Mueller, L, Kobilka, B.K. | Deposit date: | 2009-11-02 | Release date: | 2010-02-16 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor. Nature, 463, 2010
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