4K43
 
 | | Crystal structure of actin in complex with synthetic AplC tail analogue GC04 [N-{(1E,4R,5R,7E,9S,10S,11S)-4,10-dimethoxy-11-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-5,9-dimethyl-6-oxododeca-1,7-dien-1-yl}-N-methylformamide] | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Pereira, J.H, Petchprayoon, C, Moriarty, N.W, Fink, S.J, Cecere, G, Paterson, I, Adams, P.D, Marriott, G. | | Deposit date: | 2013-04-11 | | Release date: | 2014-10-01 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural and biochemical studies of actin in complex with synthetic macrolide tail analogues.
Chemmedchem, 9, 2014
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6QNS
 | | Crystal structure of the binding domain of Botulinum Neurotoxin type B mutant I1248W/V1249W in complex with human synaptotagmin 1 and GD1a receptors | | Descriptor: | Botulinum neurotoxin type B, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Synaptotagmin-1 | | Authors: | Masuyer, G, Yin, L, Zhang, S, Miyashita, S.I, Dong, M, Stenmark, P. | | Deposit date: | 2019-02-12 | | Release date: | 2020-02-26 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy.
Plos Biol., 18, 2020
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3Q1S
 | | HIV-1 neutralizing antibody Z13e1 in complex with epitope display protein | | Descriptor: | GLYCEROL, ISOPROPYL ALCOHOL, Interleukin-22, ... | | Authors: | Stanfield, R.L, Julien, J.-P, Pejchal, R, Gach, J.S, Zwick, M.B, Wilson, I.A. | | Deposit date: | 2010-12-17 | | Release date: | 2011-11-02 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structure-Based Design of a Protein Immunogen that Displays an HIV-1 gp41 Neutralizing Epitope.
J.Mol.Biol., 414, 2011
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1C7N
 | | CRYSTAL STRUCTURE OF CYSTALYSIN FROM TREPONEMA DENTICOLA CONTAINS A PYRIDOXAL 5'-PHOSPHATE COFACTOR | | Descriptor: | CYSTALYSIN, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Krupka, H.I, Huber, R, Holt, S.C, Clausen, T. | | Deposit date: | 2000-03-16 | | Release date: | 2000-07-26 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of cystalysin from Treponema denticola: a pyridoxal 5'-phosphate-dependent protein acting as a haemolytic enzyme.
EMBO J., 19, 2000
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2UYE
 | | Double mutant Y110S,F111V DntR from Burkholderia sp. strain DNT in complex with thiocyanate | | Descriptor: | GLYCEROL, REGULATORY PROTEIN, THIOCYANATE ION | | Authors: | Lonneborg, R, Smirova, I, Dian, C, leonard, G.A, McSweeney, S, Brzezinski, P. | | Deposit date: | 2007-04-04 | | Release date: | 2007-08-21 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | In Vivo and in Vitro Investigation of Transcriptional Regulation by Dntr.
J.Mol.Biol., 372, 2007
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6Z26
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1CBU
 | | ADENOSYLCOBINAMIDE KINASE/ADENOSYLCOBINAMIDE PHOSPHATE GUANYLYLTRANSFERASE (COBU) FROM SALMONELLA TYPHIMURIUM | | Descriptor: | ADENOSYLCOBINAMIDE KINASE/ADENOSYLCOBINAMIDE PHOSPHATE GUANYLYLTRANSFERASE, SULFATE ION | | Authors: | Thompson, T.B, Thomas, M.G, Escalante-Semerena, J.C, Rayment, I. | | Deposit date: | 1998-03-12 | | Release date: | 1998-12-02 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Three-dimensional structure of adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase from Salmonella typhimurium determined to 2.3 A resolution,.
Biochemistry, 37, 1998
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7QTZ
 | | Crystal structure of Iripin-1 serpin from tick Ixodes ricinus | | Descriptor: | MAGNESIUM ION, Putative salivary serpin | | Authors: | Kascakova, B, Kuta Smatanova, I, Chmelar, J, Prudnikova, T. | | Deposit date: | 2022-01-17 | | Release date: | 2023-01-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Iripin-1, a new anti-inflammatory tick serpin, inhibits leukocyte recruitment in vivo while altering the levels of chemokines and adhesion molecules.
Front Immunol, 14, 2023
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8J82
 | | GaHNL-12gen (artificial S-hydroxynitrile lyase generated by GAOptimizer) | | Descriptor: | S-hydroxynitrile lyase | | Authors: | Ozawa, H, Unno, I, Sekine, R, Ito, S, Nakano, S. | | Deposit date: | 2023-04-29 | | Release date: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Development of evolutionary algorithm-based protein redesign method
Cell Rep Phys Sci, 5, 2024
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1C9K
 | | THE THREE DIMENSIONAL STRUCTURE OF ADENOSYLCOBINAMIDE KINASE/ ADENOSYLCOBINAMIDE PHOSPHATE GUALYLYLTRANSFERASE (COBU) COMPLEXED WITH GMP: EVIDENCE FOR A SUBSTRATE INDUCED TRANSFERASE ACTIVE SITE | | Descriptor: | ADENOSYLCOBINAMIDE KINASE, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Thompson, T.B, Thomas, M.G, Esclante-Semerena, J.C, Rayment, I. | | Deposit date: | 1999-08-02 | | Release date: | 1999-08-18 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Three-dimensional structure of adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase (CobU) complexed with GMP: evidence for a substrate-induced transferase active site.
Biochemistry, 38, 1999
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5DJF
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5DJI
 | | Structure of M. tuberculosis CysQ, a PAP phosphatase with AMP, PO4, and 2Mg bound | | Descriptor: | 3'-phosphoadenosine 5'-phosphate phosphatase, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Fisher, A.J, Erickson, A.I. | | Deposit date: | 2015-09-02 | | Release date: | 2015-11-11 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.659 Å) | | Cite: | Crystal Structures of Mycobacterium tuberculosis CysQ, with Substrate and Products Bound.
Biochemistry, 54, 2015
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6YWW
 | | MeCP2 is a microsatellite binding protein that protects CA repeats from nucleosome invasion | | Descriptor: | DNA (5'-D(*AP*TP*AP*TP*AP*AP*TP*TP*GP*TP*GP*TP*GP*TP*GP*TP*GP*CP*AP*G)-3'), DNA/RNA (5'-D(*TP*CP*TP*GP*CP*AP*CP*A)-R(P*(5HC))-D(P*AP*CP*AP*CP*AP*AP*TP*TP*AP*TP*A)-3'), Truncated methyl CpG binding protein 2 transcript 1 | | Authors: | Ibrahim, A, Papin, C, Mohideen-Abdul, K, Gras, S.L, Stoll, I, Bronner, C, Dimitrov, S, Klaholz, B.P, Hamiche, A. | | Deposit date: | 2020-04-30 | | Release date: | 2021-06-16 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.102 Å) | | Cite: | MeCP2 is a microsatellite binding protein that protects CA repeats from nucleosome invasion.
Science, 372, 2021
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8J5H
 | | Crystal structure of kinase AbmG in complex with 4'-hydroxy-4'-thiocytidine | | Descriptor: | 4-azanyl-1-[(2~{R},3~{R},4~{S},5~{S})-5-(hydroxymethyl)-3,4,5-tris(oxidanyl)thiolan-2-yl]pyrimidin-2-one, Deoxyadenosine/deoxycytidine kinase, NITRATE ION | | Authors: | Ushimaru, R, Mori, T, Liu, H.-w, Abe, I. | | Deposit date: | 2023-04-22 | | Release date: | 2024-04-24 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal structure of kinase AbmG in complex with 4'-hydroxy-4'-thiocytidine
To Be Published
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8J2O
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2V1R
 | | Yeast Pex13 SH3 domain complexed with a peptide from Pex14 at 2.1 A resolution | | Descriptor: | PEROXISOMAL MEMBRANE PROTEIN PAS20, PEX14 | | Authors: | Kursula, I, Kursula, P, Lehmann, F, Zou, P, Song, Y.H, Wilmanns, M. | | Deposit date: | 2007-05-29 | | Release date: | 2008-06-03 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Genomics of Yeast SH3 Domains
To be Published
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5DJG
 | | Structure of M. tuberculosis CysQ, a PAP phosphatase with PAP, Mg, and Li bound | | Descriptor: | 3'-phosphoadenosine 5'-phosphate phosphatase, ADENOSINE-3'-5'-DIPHOSPHATE, LITHIUM ION, ... | | Authors: | Fisher, A.J, Erickson, A.I. | | Deposit date: | 2015-09-02 | | Release date: | 2015-11-11 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.951 Å) | | Cite: | Crystal Structures of Mycobacterium tuberculosis CysQ, with Substrate and Products Bound.
Biochemistry, 54, 2015
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5DJH
 | | Structure of M. tuberculosis CysQ, a PAP phosphatase with AMP, PO4, and 3Mg bound | | Descriptor: | 3'-phosphoadenosine 5'-phosphate phosphatase, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Fisher, A.J, Erickson, A.I. | | Deposit date: | 2015-09-02 | | Release date: | 2015-11-11 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.451 Å) | | Cite: | Crystal Structures of Mycobacterium tuberculosis CysQ, with Substrate and Products Bound.
Biochemistry, 54, 2015
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2UXA
 | | Crystal structure of the GluR2-flip ligand binding domain, r/g unedited. | | Descriptor: | GLUTAMATE RECEPTOR SUBUNIT GLUR2-FLIP, GLUTAMIC ACID, ZINC ION | | Authors: | Greger, I.H, Akamine, P, Khatri, L, Ziff, E.B. | | Deposit date: | 2007-03-27 | | Release date: | 2007-04-10 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Developmentally Regulated, Combinatorial RNA Processing Modulates Ampa Receptor Biogenesis.
Neuron, 51, 2006
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4ZES
 | | Blood dendritic cell antigen 2 (BDCA-2) complexed with methyl-mannoside | | Descriptor: | C-type lectin domain family 4 member C, CALCIUM ION, MAGNESIUM ION, ... | | Authors: | Jegouzo, S.A.F, Feinberg, H, Dungarwalla, T, Drickamer, K, Weis, W.I, Taylor, M.E. | | Deposit date: | 2015-04-20 | | Release date: | 2015-05-27 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | A Novel Mechanism for Binding of Galactose-terminated Glycans by the C-type Carbohydrate Recognition Domain in Blood Dendritic Cell Antigen 2.
J.Biol.Chem., 290, 2015
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3LV8
 | | 1.8 Angstrom resolution crystal structure of a thymidylate kinase (tmk) from Vibrio cholerae O1 biovar eltor str. N16961 in complex with TMP, thymidine-5'-diphosphate and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Halavaty, A.S, Minasov, G, Dubrovska, I, Winsor, J, Shuvalova, L, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2010-02-19 | | Release date: | 2010-03-02 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | 1.8 Angstrom resolution crystal structure of a thymidylate kinase (tmk) from Vibrio cholerae O1 biovar eltor str. N16961 in complex with TMP, thymidine-5'-diphosphate and ADP
To be Published
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5DJJ
 | | Structure of M. tuberculosis CysQ, a PAP phosphatase with PO4 and 2Mg bound | | Descriptor: | 3'-phosphoadenosine 5'-phosphate phosphatase, MAGNESIUM ION, PHOSPHATE ION, ... | | Authors: | Fisher, A.J, Erickson, A.I. | | Deposit date: | 2015-09-02 | | Release date: | 2015-11-11 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.501 Å) | | Cite: | Crystal Structures of Mycobacterium tuberculosis CysQ, with Substrate and Products Bound.
Biochemistry, 54, 2015
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4ZGV
 | | The Crystal Structure of the Ferredoxin Receptor FusA from Pectobacterium atrosepticum SCRI1043 | | Descriptor: | Ferredoxin receptor, LAURYL DIMETHYLAMINE-N-OXIDE, octyl beta-D-glucopyranoside | | Authors: | Grinter, R, Josts, I, Roszak, A.W, Cogdell, R.J, Walker, D. | | Deposit date: | 2015-04-24 | | Release date: | 2016-08-31 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure of the bacterial plant-ferredoxin receptor FusA.
Nat Commun, 7, 2016
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4B2S
 | | Solution structure of CCP modules 11-12 of complement factor H | | Descriptor: | COMPLEMENT FACTOR H | | Authors: | Makou, E, Mertens, H.D, Maciejewski, M, Soares, D.C, Matis, I, Schmidt, C.Q, Herbert, A.P, Svergun, D.I, Barlow, P.N. | | Deposit date: | 2012-07-17 | | Release date: | 2012-10-17 | | Last modified: | 2013-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of Ccp Modules 10-12 Illuminates Functional Architecture of the Complement Regulator, Factor H.
J.Mol.Biol., 424, 2012
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5FAA
 | | Crystal structure of C-terminal domain of shaft pilin spaA from Lactobacillus rhamnosus GG, - I422 space group | | Descriptor: | 1,2-ETHANEDIOL, Cell surface protein SpaA | | Authors: | Chaurasia, P, Pratap, S, von Ossowski, I, Palva, A, Krishnan, V. | | Deposit date: | 2015-12-11 | | Release date: | 2016-07-20 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | New insights about pilus formation in gut-adapted Lactobacillus rhamnosus GG from the crystal structure of the SpaA backbone-pilin subunit
Sci Rep, 6, 2016
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