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PDB: 139 results

3E1R
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BU of 3e1r by Molmil
Midbody targeting of the ESCRT machinery by a non-canonical coiled-coil in CEP55
Descriptor: Centrosomal protein of 55 kDa, Programmed cell death 6-interacting protein
Authors:Lee, H.H, Elia, N, Ghirlando, R, Lippincott-Schwartz, J, Hurley, J.H.
Deposit date:2008-08-04
Release date:2008-11-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Midbody targeting of the ESCRT machinery by a noncanonical coiled coil in CEP55.
Science, 322, 2008
3EAB
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BU of 3eab by Molmil
Crystal structure of Spastin MIT in complex with ESCRT III
Descriptor: CHMP1b, Spastin
Authors:Yang, D, Rimanchi, N, Renvoise, B, Lippincott-Schwartz, J, Blackstone, C, Hurley, J.H.
Deposit date:2008-08-25
Release date:2008-11-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B.
Nat.Struct.Mol.Biol., 15, 2008
5C50
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BU of 5c50 by Molmil
Crystal structure of the complex of human Atg101-Atg13 HORMA domain
Descriptor: Autophagy-related protein 101, Autophagy-related protein 13, BENZAMIDINE
Authors:Qi, S, Hurley, J.H.
Deposit date:2015-06-19
Release date:2015-10-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structure of the Human Atg13-Atg101 HORMA Heterodimer: an Interaction Hub within the ULK1 Complex.
Structure, 23, 2015
5HM9
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BU of 5hm9 by Molmil
Crystal structure of MamO protease domain from Magnetospirillum magneticum (apo form)
Descriptor: MamO protease domain, poly(UNK)
Authors:Hershey, D.M, Ren, X, Hurley, J.H, Komeili, A.
Deposit date:2016-01-15
Release date:2016-03-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:MamO Is a Repurposed Serine Protease that Promotes Magnetite Biomineralization through Direct Transition Metal Binding in Magnetotactic Bacteria.
Plos Biol., 14, 2016
5HMA
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BU of 5hma by Molmil
Crystal structure of MamO protease domain from Magnetospirillum magneticum (Ni bound form)
Descriptor: CHLORIDE ION, NICKEL (II) ION, Trypsin-like serine protease, ...
Authors:Hershey, D.M, Ren, X, Hurley, J.H, Komeili, A.
Deposit date:2016-01-15
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:MamO Is a Repurposed Serine Protease that Promotes Magnetite Biomineralization through Direct Transition Metal Binding in Magnetotactic Bacteria.
Plos Biol., 14, 2016
1GRO
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BU of 1gro by Molmil
REGULATORY AND CATALYTIC MECHANISMS IN ESCHERICHIA COLI ISOCITRATE DEHYDROGENASE: MULTIPLE ROLES FOR N115
Descriptor: ISOCITRATE DEHYDROGENASE, ISOCITRIC ACID, MAGNESIUM ION
Authors:Grobler, J.A, Hurley, J.H.
Deposit date:1995-10-12
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Second-site suppression of regulatory phosphorylation in Escherichia coli isocitrate dehydrogenase.
Protein Sci., 5, 1996
1GRP
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BU of 1grp by Molmil
REGULATORY AND CATALYTIC MECHANISMS IN ESCHERICHIA COLI ISOCITRATE DEHYDROGENASE: MULTIPLE ROLES FOR N115
Descriptor: ISOCITRATE DEHYDROGENASE, ISOCITRIC ACID, MAGNESIUM ION
Authors:Grobler, J.A, Hurley, J.H.
Deposit date:1995-10-12
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Second-site suppression of regulatory phosphorylation in Escherichia coli isocitrate dehydrogenase.
Protein Sci., 5, 1996
3TOW
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BU of 3tow by Molmil
Crystal Structure of the MABP Domain of MVB12B of Human ESCRT-I Complex
Descriptor: Multivesicular body subunit 12B
Authors:Boura, E, Hurley, J.H.
Deposit date:2011-09-06
Release date:2012-01-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Structural basis for membrane targeting by the MVB12-associated beta-prism domain of the human ESCRT-I MVB12 subunit.
Proc.Natl.Acad.Sci.USA, 109, 2012
2F66
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BU of 2f66 by Molmil
Structure of the ESCRT-I endosomal trafficking complex
Descriptor: Protein SRN2, SULFATE ION, Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease, ...
Authors:Kostelansky, M.S, Lee, S, Kim, J, Hurley, J.H.
Deposit date:2005-11-28
Release date:2006-04-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and functional organization of the ESCRT-I trafficking complex.
Cell(Cambridge,Mass.), 125, 2006
2FIF
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BU of 2fif by Molmil
Crystal Structure of a Bovine Rabex-5 fragment complexed with ubiquitin
Descriptor: Rab5 GDP/GTP exchange factor, SULFATE ION, Ubiquitin, ...
Authors:Lee, S, Hurley, J.H.
Deposit date:2005-12-29
Release date:2006-02-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5
Nat.Struct.Mol.Biol., 13, 2006
2FID
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BU of 2fid by Molmil
Crystal Structure of a Bovine Rabex-5 fragment complexed with ubiquitin
Descriptor: Rab5 GDP/GTP exchange factor, Ubiquitin, ZINC ION
Authors:Lee, S, Hurley, J.H.
Deposit date:2005-12-29
Release date:2006-02-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5
Nat.Struct.Mol.Biol., 13, 2006
2PJW
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BU of 2pjw by Molmil
The Vps27/Hse1 complex is a GAT domain-based scaffold for ubiquitin-dependent sorting
Descriptor: Uncharacterized protein YHL002W, Vacuolar protein sorting-associated protein 27
Authors:Prag, G, Hurley, J.H.
Deposit date:2007-04-16
Release date:2007-06-05
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:The Vps27/Hse1 Complex Is a GAT Domain-Based Scaffold for Ubiquitin-Dependent Sorting.
Dev.Cell, 12, 2007
1SZI
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BU of 1szi by Molmil
Crystal Structure of the C-terminus of TIP47
Descriptor: mannose-6-phosphate receptor binding protein 1
Authors:Hickenbottom, S.J, Kimmel, A.R, Londos, C, Hurley, J.H.
Deposit date:2004-04-05
Release date:2004-07-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a Lipid Droplet Protein: The PAT Family Member TIP47
Structure, 12, 2004
1TLA
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BU of 1tla by Molmil
HYDROPHOBIC CORE REPACKING AND AROMATIC-AROMATIC INTERACTION IN THE THERMOSTABLE MUTANT OF T4 LYSOZYME SER 117 (RIGHT ARROW) PHE
Descriptor: CHLORIDE ION, PHOSPHATE ION, T4 LYSOZYME
Authors:Anderson, D.E, Hurley, J.H, Nicholson, H, Baase, W.A, Matthews, B.W.
Deposit date:1993-03-22
Release date:1993-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hydrophobic core repacking and aromatic-aromatic interaction in the thermostable mutant of T4 lysozyme Ser 117-->Phe.
Protein Sci., 2, 1993
1U5T
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BU of 1u5t by Molmil
Structure of the ESCRT-II endosomal trafficking complex
Descriptor: Defective in vacuolar protein sorting; Vps36p, Hypothetical 23.6 kDa protein in YUH1-URA8 intergenic region, appears to be functionally related to SNF7; Snf8p
Authors:Hierro, A, Sun, J, Rusnak, A.S, Kim, J, Prag, G, Emr, S.D, Hurley, J.H.
Deposit date:2004-07-28
Release date:2004-09-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure of ESCRT-II endosomal trafficking complex
Nature, 431, 2004
7JTL
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BU of 7jtl by Molmil
Structure of SARS-CoV-2 ORF8 accessory protein
Descriptor: ORF8 protein, SODIUM ION
Authors:Flower, T.G, Buffalo, C.Z, Hooy, R.M, Allaire, M, Ren, X, Hurley, J.H.
Deposit date:2020-08-18
Release date:2020-08-26
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structure of SARS-CoV-2 ORF8, a rapidly evolving immune evasion protein.
Proc.Natl.Acad.Sci.USA, 118, 2021
1TZD
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BU of 1tzd by Molmil
CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF INOSITOL 1,4,5-TRISPHOSPHATE 3-KINASE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Inositol-trisphosphate 3-kinase A, MAGNESIUM ION
Authors:Miller, G.J, Hurley, J.H.
Deposit date:2004-07-09
Release date:2004-09-21
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the catalytic core of inositol 1,4,5-trisphosphate 3-kinase
Mol.Cell, 15, 2004
3OBU
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BU of 3obu by Molmil
Crystal structure of the Tsg101 UEV domain in complex with a HIV-1 PTAP peptide
Descriptor: Gag polyprotein, Tumor susceptibility gene 101 protein
Authors:Im, Y.J, Hurley, J.H.
Deposit date:2010-08-09
Release date:2010-12-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic and Functional Analysis of the ESCRT-I /HIV-1 Gag PTAP Interaction.
Structure, 18, 2010
3PFQ
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BU of 3pfq by Molmil
Crystal Structure and Allosteric Activation of Protein Kinase C beta II
Descriptor: CALCIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein kinase C beta type, ...
Authors:Leonard, T.A, Rozycki, B, Saidi, L.F, Hummer, G, Hurley, J.H.
Deposit date:2010-10-28
Release date:2011-02-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal Structure and Allosteric Activation of Protein Kinase C beta II
Cell(Cambridge,Mass.), 144, 2011
1P3Q
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BU of 1p3q by Molmil
Mechanism of Ubiquitin Recognition by the CUE Domain of VPS9
Descriptor: Ubiquitin, Vacuolar protein sorting-associated protein VPS9
Authors:Prag, G, Misra, S, Jones, E.A, Ghirlando, R, Davies, B.A, Horazdovsky, B.F, Hurley, J.H.
Deposit date:2003-04-18
Release date:2003-06-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanism of Ubiquitin Recognition by the CUE Domain of Vps9p.
Cell(Cambridge,Mass.), 113, 2003
3R42
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BU of 3r42 by Molmil
Crystal structure of the yeast vps23 UEV domain in complex with a vps27 PSDP peptide
Descriptor: Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease, Vacuolar protein sorting-associated protein 27
Authors:Ren, X, Hurley, J.H.
Deposit date:2011-03-17
Release date:2011-05-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.866 Å)
Cite:Structural basis for endosomal recruitment of ESCRT-I by ESCRT-0 in yeast.
Embo J., 30, 2011
1AB8
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BU of 1ab8 by Molmil
RAT TYPE II ADENYLYL CYCLASE C2 DOMAIN/FORSKOLIN COMPLEX
Descriptor: ADENYLYL CYCLASE, FORSKOLIN
Authors:Zhang, G, Hurley, J.H.
Deposit date:1997-02-04
Release date:1997-05-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the adenylyl cyclase catalytic core.
Nature, 386, 1997
3R3Q
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BU of 3r3q by Molmil
Crystal structure of the yeast Vps23 UEV domain
Descriptor: ACETATE ION, CHLORIDE ION, IMIDAZOLE, ...
Authors:Ren, X, Hurley, J.H.
Deposit date:2011-03-16
Release date:2011-05-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural basis for endosomal recruitment of ESCRT-I by ESCRT-0 in yeast.
Embo J., 30, 2011
1BO1
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BU of 1bo1 by Molmil
PHOSPHATIDYLINOSITOL PHOSPHATE KINASE TYPE II BETA
Descriptor: PROTEIN (PHOSPHATIDYLINOSITOL PHOSPHATE KINASE IIBETA)
Authors:Rao, V.D, Misra, S, Boronenkov, I.V, Anderson, R.A, Hurley, J.H.
Deposit date:1998-08-02
Release date:1998-10-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of type IIbeta phosphatidylinositol phosphate kinase: a protein kinase fold flattened for interfacial phosphorylation.
Cell(Cambridge,Mass.), 94, 1998
3OBQ
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BU of 3obq by Molmil
Crystal Structure of the Tsg101 UEV domain in complex with a human HRS PSAP peptide
Descriptor: Hepatocyte growth factor-regulated tyrosine kinase substrate, Tumor susceptibility gene 101 protein
Authors:Im, Y.J, Hurley, J.H.
Deposit date:2010-08-09
Release date:2010-12-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystallographic and Functional Analysis of the ESCRT-I /HIV-1 Gag PTAP Interaction.
Structure, 18, 2010

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