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PDB: 83 件

3HFB
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Crystal structure of human tryoptophan hydroxylase type 1 with LP-534193
分子名称: 4-(5-{[(2'-methylbiphenyl-2-yl)methyl]amino}pyrazin-2-yl)-L-phenylalanine, FE (III) ION, Tryptophan 5-hydroxylase 1
著者Tari, L.W, Swanson, R.V, Hunter, M.J.
登録日2009-05-11
公開日2010-04-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Mechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic Analysis.
Curr Chem Genomics, 4, 2010
3HF6
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Crystal structure of human tryptophan hydroxylase type 1 with bound LP-521834 and FE
分子名称: 4-(4-amino-6-{[(1R)-1-naphthalen-2-ylethyl]amino}-1,3,5-triazin-2-yl)-L-phenylalanine, FE (III) ION, Tryptophan 5-hydroxylase 1
著者Tari, L.W, Swanson, R.V, Hunter, M.J.
登録日2009-05-11
公開日2009-11-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic Analysis
Curr Chem Genomics, 4, 2010
3HF8
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Crystal structure of human tryoptophan hydroxylase type 1 with bound LP-533401 and Fe
分子名称: 4-{2-amino-6-[(1R)-2,2,2-trifluoro-1-(3'-fluorobiphenyl-4-yl)ethoxy]pyrimidin-4-yl}-L-phenylalanine, FE (III) ION, Tryptophan 5-hydroxylase 1
著者Tari, L.W, Swanson, R.V, Hunter, M.J.
登録日2009-05-11
公開日2010-04-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Mechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic Analysis.
Curr Chem Genomics, 4, 2010
1ADX
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FIFTH EGF-LIKE DOMAIN OF THROMBOMODULIN (TMEGF5), NMR, 14 STRUCTURES
分子名称: THROMBOMODULIN
著者Sampoli-Benitez, B.A, Hunter, M.J, Meininger, D.P, Komives, E.A.
登録日1997-02-18
公開日1997-12-24
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Structure of the fifth EGF-like domain of thrombomodulin: An EGF-like domain with a novel disulfide-bonding pattern.
J.Mol.Biol., 273, 1997
2ADX
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FIFTH EGF-LIKE DOMAIN OF THROMBOMODULIN (TMEGF5), NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: THROMBOMODULIN
著者Sampoli-Benitez, B.A, Hunter, M.J, Meininger, D.P, Komives, E.A.
登録日1997-02-18
公開日1997-12-24
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Structure of the fifth EGF-like domain of thrombomodulin: An EGF-like domain with a novel disulfide-bonding pattern.
J.Mol.Biol., 273, 1997
2Q5G
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BU of 2q5g by Molmil
Ligand binding domain of PPAR delta receptor in complex with a partial agonist
分子名称: Peroxisome proliferator-activated receptor delta, [(7-{[2-(3-MORPHOLIN-4-YLPROP-1-YN-1-YL)-6-{[4-(TRIFLUOROMETHYL)PHENYL]ETHYNYL}PYRIDIN-4-YL]THIO}-2,3-DIHYDRO-1H-INDEN- 4-YL)OXY]ACETIC ACID
著者Pettersson, I, Sauerberg, P, Johansson, E, Hoffman, I, Tari, L.W, Hunter, M.J, Nix, J.
登録日2007-06-01
公開日2008-06-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Design of a partial PPARdelta agonist.
Bioorg.Med.Chem.Lett., 17, 2007
1G27
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CRYSTAL STRUCTURE OF E.COLI POLYPEPTIDE DEFORMYLASE COMPLEXED WITH THE INHIBITOR BB-3497
分子名称: 2-[(FORMYL-HYDROXY-AMINO)-METHYL]-HEXANOIC ACID (1-DIMETHYLCARBAMOYL-2,2-DIMETHYL-PROPYL)-AMIDE, NICKEL (II) ION, POLYPEPTIDE DEFORMYLASE
著者Clements, J.M, Beckett, P, Brown, A, Catlin, C, Lobell, M, Palan, S, Thomas, W, Whittaker, M, Baker, P.J, Rodgers, H.F, Barynin, V, Rice, D.W, Hunter, M.G.
登録日2000-10-17
公開日2001-10-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Antibiotic activity and characterization of BB-3497, a novel peptide deformylase inhibitor.
Antimicrob.Agents Chemother., 45, 2001
1G2A
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THE CRYSTAL STRUCTURE OF E.COLI PEPTIDE DEFORMYLASE COMPLEXED WITH ACTINONIN
分子名称: ACTINONIN, NICKEL (II) ION, POLYPEPTIDE DEFORMYLASE
著者Clements, J.M, Beckett, P, Brown, A, Catlin, C, Lobell, M, Palan, S, Thomas, W, Whittaker, M, Baker, P.J, Rodgers, H.F, Barynin, V, Rice, D.W, Hunter, M.G.
登録日2000-10-18
公開日2001-10-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Antibiotic activity and characterization of BB-3497, a novel peptide deformylase inhibitor.
Antimicrob.Agents Chemother., 45, 2001
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