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PDB: 735 件

4CH2
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BU of 4ch2 by Molmil
Low-salt crystal structure of a thrombin-GpIbalpha peptide complex
分子名称: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, GLYCEROL, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, ...
著者Lechtenberg, B.C, Freund, S.M.V, Huntington, J.A.
登録日2013-11-28
公開日2013-12-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Gpibalpha Interacts Exclusively with Exosite II of Thrombin
J.Mol.Biol., 426, 2014
2OL2
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High Resolution Structure of Native PCI in Space Group P21
分子名称: GLYCEROL, Plasma serine protease inhibitor
著者Li, W, Huntington, J.A.
登録日2007-01-18
公開日2007-03-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of native protein C inhibitor provides insight into its multiple functions.
J.Biol.Chem., 282, 2007
1R1L
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BU of 1r1l by Molmil
Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous tripeptide (formyl-norleucine-LF)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin P14-P9 peptide, Antithrombin-III, ...
著者Zhou, A, Huntington, J.A, Lomas, D.A, Stein, P.E, Carrell, R.W.
登録日2003-09-24
公開日2004-10-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Serpins and the design of peptides to block intermolecular beta-linkages
To be Published
1JMO
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Crystal Structure of the Heparin Cofactor II-S195A Thrombin Complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Baglin, T.P, Carrell, R.W, Esmon, C.T, Huntington, J.A.
登録日2001-07-19
公開日2002-08-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism.
Proc.Natl.Acad.Sci.USA, 99, 2002
3HZG
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BU of 3hzg by Molmil
Crystal structure of mycobacterium tuberculosis thymidylate synthase X bound with FAD
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, PHOSPHATE ION, ...
著者Staker, B.L, Rathod, P, Hunter, J, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-06-23
公開日2009-07-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
1JMJ
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BU of 1jmj by Molmil
Crystal Structure of Native Heparin Cofactor II
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HEPARIN COFACTOR II, ...
著者Baglin, T.P, Carrell, R.W, Church, F.C, Huntington, J.A.
登録日2001-07-18
公開日2002-08-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism.
Proc.Natl.Acad.Sci.USA, 99, 2002
3GIS
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BU of 3gis by Molmil
Crystal Structure of Na-free Thrombin in Complex with Thrombomodulin
分子名称: CALCIUM ION, Prothrombin, SULFATE ION, ...
著者Adams, T.E, Huntington, J.A.
登録日2009-03-06
公開日2009-08-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis of thrombomodulin activation of slow thrombin
J.Thromb.Haemost., 7, 2009
2HIJ
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Crystal Structure of P14 Alanine Variant of Antithrombin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, ...
著者Luis, S.A, Bock, S.C, Huntington, J.A.
登録日2006-06-29
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of P14 Alanine Variant of Antithrombin
To be Published
3K65
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Crystal Structure of Prethombin-2/Fragment-2 Complex
分子名称: 1,4-BUTANEDIOL, Prothrombin
著者Adams, T.E, Huntington, J.A.
登録日2009-10-08
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural transitions during prothrombin activation: On the importance of fragment 2.
Biochimie, 122, 2016
3DY0
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BU of 3dy0 by Molmil
Crystal Structure of Cleaved PCI Bound to Heparin
分子名称: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, C-terminus Plasma serine protease inhibitor, GLYCEROL, ...
著者Li, W, Huntington, J.A.
登録日2008-07-25
公開日2008-10-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The heparin binding site of protein C inhibitor is protease-dependent.
J.Biol.Chem., 283, 2008

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件を2024-07-17に公開中

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