1U9M
 
 | | Crystal structure of F58W mutant of cytochrome b5 | | 分子名称: | Cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Shan, L, Lu, J.-X, Gan, J.-H, Wang, Y.-H, Huang, Z.-X, Xia, Z.-X. | | 登録日 | 2004-08-10 | | 公開日 | 2005-02-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of the F58W mutant of cytochrome b5: the mutation leads to multiple conformations and weakens stacking interactions.
Acta Crystallogr.,Sect.D, 61, 2005
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1M2M
 | | Crystal structure of E44A/E48A/E56A/D60A mutant of cytochrome b5 | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, cytochrome b5 | | 著者 | Wu, J, Wang, Y.-H, Gan, J.-H, Wang, W.-H, Sun, B.-Y, Huang, Z.-X, Xia, Z.-X. | | 登録日 | 2002-06-24 | | 公開日 | 2003-03-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of Cytochrome b5 Mutated at the Charged Surface-Residues and Their Interactions with Cytochrome c
Chin.J.Chem., 20, 2002
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3KQ8
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2R7Y
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3HGA
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3IFI
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3IKI
 | | 5-SMe-dU containing DNA octamer | | 分子名称: | 5'-D(*GP*(UMS)P*GP*(US2)P*AP*CP*AP*C)-3', MAGNESIUM ION | | 著者 | Sheng, J, Hassan, A.E.A, Zhang, W, Gan, J, Huang, Z. | | 登録日 | 2009-08-05 | | 公開日 | 2010-03-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Hydrogen bond formation between the naturally modified nucleobase and phosphate backbone.
Nucleic Acids Res., 40, 2012
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3LTR
 | | 5-OMe-dU containing DNA 8mer | | 分子名称: | 5'-D(*GP*(UMS)P*GP*(T5O)P*AP*CP*AP*C)-3', MAGNESIUM ION | | 著者 | Sheng, J, Hassan, A.E.A, Zhang, W, Gan, J, Huang, Z. | | 登録日 | 2010-02-16 | | 公開日 | 2010-03-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Hydrogen bond formation between the naturally modified nucleobase and phosphate backbone.
Nucleic Acids Res., 40, 2012
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6NUD
 | | Small conformation of ssRNA-bound CRISPR_Csm complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms protein Csm2, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ... | | 著者 | Zhang, K, Pintilie, G, Li, S, Zhu, Y, Chiu, W, Huang, Z. | | 登録日 | 2019-01-31 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry.
Cell Res., 29, 2019
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6NUE
 | | Small conformation of apo CRISPR_Csm complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms protein Csm2, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ... | | 著者 | Zhang, K, Pintilie, G, Li, S, Zhu, Y, Chiu, W, Huang, Z. | | 登録日 | 2019-01-31 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry.
Cell Res., 29, 2019
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3IJN
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8ILD
 | | The crystal structure of native dGTP:DNApre-I:Pol X substrate ternary complex | | 分子名称: | DNA (5'-D(*CP*AP*GP*GP*AP*TP*CP*CP*T)-3'), GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... | | 著者 | Qin, T, Chen, Y.Q, Gan, J.H, Huang, Z. | | 登録日 | 2023-03-03 | | 公開日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom.
Int J Mol Sci, 24, 2023
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8ILG
 | | The crystal structure of dG-DNA:Pol X product binary complex | | 分子名称: | DNA (5'-D(*CP*GP*GP*AP*TP*CP*CP*G)-3'), FORMIC ACID, MANGANESE (II) ION, ... | | 著者 | Qin, T, Gan, J.H, Huang, Z. | | 登録日 | 2023-03-03 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.805 Å) | | 主引用文献 | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom.
Int J Mol Sci, 24, 2023
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8ILE
 | | The crystal structure of dGTPalphaSe-Rp:DNApre-II:Pol X substrate ternary complex | | 分子名称: | DNA (5'-D(*CP*TP*GP*GP*AP*TP*CP*CP*A)-3'), MANGANESE (II) ION, Repair DNA polymerase X, ... | | 著者 | Qin, T, Gan, J.H, Huang, Z. | | 登録日 | 2023-03-03 | | 公開日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom.
Int J Mol Sci, 24, 2023
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8ILF
 | | The crystal structure of dGTPalphaSe-Sp:DNApre-II:Pol X substrate ternary complex | | 分子名称: | DNA (5'-D(*CP*TP*GP*GP*AP*TP*CP*CP*A)-3'), MANGANESE (II) ION, Repair DNA polymerase X, ... | | 著者 | Qin, T, Zhao, Q.W, Gan, J.H, Huang, Z. | | 登録日 | 2023-03-03 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom.
Int J Mol Sci, 24, 2023
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3K18
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4RHD
 | | DNA Duplex with Novel ZP Base Pair | | 分子名称: | DNA 9mer novel P nucleobase, DNA 9mer novel Z nucleobase, MAGNESIUM ION | | 著者 | Zhang, W, Zhang, L, Benner, S, Huang, Z. | | 登録日 | 2014-10-01 | | 公開日 | 2015-07-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Evolution of functional six-nucleotide DNA.
J.Am.Chem.Soc., 137, 2015
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5TSL
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5TSK
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2DLJ
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2NWN
 | | New Pharmacophore for Serine Protease Inhibition Revealed by Crystal Structure of Human Urokinase-type Plasminogen Activator Complexed with a Cyclic Peptidyl Inhibitor, upain-1 | | 分子名称: | Plasminogen activator, urokinase, upain-1 | | 著者 | Zhao, G, Yuan, C, Wind, T, Andreasen, P.A, Huang, Z, Huang, M, Structural Genomics Consortium (SGC) | | 登録日 | 2006-11-16 | | 公開日 | 2007-10-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural basis of specificity of a peptidyl urokinase inhibitor, upain-1
J.Struct.Biol., 160, 2007
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2O8U
 | | Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors | | 分子名称: | BENZAMIDINE, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | | 著者 | Zhao, G, Yuan, C, Jiang, L, Huang, Z, Huang, M. | | 登録日 | 2006-12-12 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors
To be Published
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2O8T
 | | Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q) in complex with Inhibitors | | 分子名称: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, SULFATE ION, ... | | 著者 | Zhao, G, Yuan, C, Jiang, L, Huang, Z, Huang, M. | | 登録日 | 2006-12-12 | | 公開日 | 2007-12-25 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors
To be Published
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2O8W
 | | Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors | | 分子名称: | 1-phenylguanidine, SULFATE ION, TETRAETHYLENE GLYCOL, ... | | 著者 | Zhao, G, Yuan, C, Jiang, L, Huang, Z, Huang, M. | | 登録日 | 2006-12-12 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors
To be Published
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3HG8
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