5YYU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yyu by Molmil](/molmil-images/mine/5yyu) | |
7L1E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7l1e by Molmil](/molmil-images/mine/7l1e) | The Crystal Structure of Bromide-Bound GtACR1 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Anion channelrhodopsin-1, BROMIDE ION, ... | Authors: | Li, H, Huang, C.Y, Wang, M, Spudich, J.L, Zheng, L. | Deposit date: | 2020-12-14 | Release date: | 2021-05-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The crystal structure of bromide-bound Gt ACR1 reveals a pre-activated state in the transmembrane anion tunnel. Elife, 10, 2021
|
|
5YKD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ykd by Molmil](/molmil-images/mine/5ykd) | |
7VUM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vum by Molmil](/molmil-images/mine/7vum) | Crystal structure of SSB complexed with que | Descriptor: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, Single-stranded DNA-binding protein | Authors: | Lin, E.S, Huang, Y.H, Huang, C.Y. | Deposit date: | 2021-11-03 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.319 Å) | Cite: | A Complexed Crystal Structure of a Single-Stranded DNA-Binding Protein with Quercetin and the Structural Basis of Flavonol Inhibition Specificity. Int J Mol Sci, 23, 2022
|
|
5XGT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xgt by Molmil](/molmil-images/mine/5xgt) | |
5YNZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ynz by Molmil](/molmil-images/mine/5ynz) | Crystal structure of the dihydroorotase domain (K1556A) of human CAD | Descriptor: | CAD protein, ZINC ION | Authors: | Huang, Y.H, Chen, K.L, Cheng, J.H, Huang, C.Y. | Deposit date: | 2017-10-26 | Release date: | 2018-10-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.774 Å) | Cite: | Crystal structures of monometallic dihydropyrimidinase and the human dihydroorotase domain K1556A mutant reveal no lysine carbamylation within the active site Biochem. Biophys. Res. Commun., 505, 2018
|
|
5YUO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yuo by Molmil](/molmil-images/mine/5yuo) | |
6I59
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6i59 by Molmil](/molmil-images/mine/6i59) | Long wavelength native-SAD phasing of Sen1 helicase | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Basu, S, Olieric, V, Matsugaki, N, Kawano, Y, Takashi, T, Huang, C.Y, Leonarski, F, Yamada, Y, Vera, L, Olieric, N, Basquin, J, Wojdyla, J.A, Diederichs, K, Yamamoto, M, Bunk, O, Wang, M. | Deposit date: | 2018-11-13 | Release date: | 2019-03-13 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Long-wavelength native-SAD phasing: opportunities and challenges. Iucrj, 6, 2019
|
|
5YUN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yun by Molmil](/molmil-images/mine/5yun) | Crystal structure of SSB complexed with myc | Descriptor: | 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, Single-stranded DNA-binding protein | Authors: | Huang, Y.H, Huang, C.Y. | Deposit date: | 2017-11-22 | Release date: | 2018-10-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Crystal structure of SSB complexed with inhibitor myricetin. Biochem. Biophys. Res. Commun., 504, 2018
|
|
6JDG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jdg by Molmil](/molmil-images/mine/6jdg) | Complexed crystal structure of PaSSB with ssDNA dT20 at 2.39 angstrom resolution | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Single-stranded DNA-binding protein | Authors: | Huang, Y.H, Huang, C.Y. | Deposit date: | 2019-02-01 | Release date: | 2019-12-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.388 Å) | Cite: | Complexed crystal structure of SSB reveals a novel single-stranded DNA binding mode (SSB)3:1: Phe60 is not crucial for defining binding paths. Biochem.Biophys.Res.Commun., 520, 2019
|
|
6IRQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6irq by Molmil](/molmil-images/mine/6irq) | |
6KLK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6klk by Molmil](/molmil-images/mine/6klk) | |
6L0I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6l0i by Molmil](/molmil-images/mine/6l0i) | Crystal structure of dihydroorotase in complex with malate at pH6.5 from Saccharomyces cerevisiae | Descriptor: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | Authors: | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | Deposit date: | 2019-09-26 | Release date: | 2020-12-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
|
|
6L0F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6l0f by Molmil](/molmil-images/mine/6l0f) | Crystal structure of dihydroorotase in complex with 5-Aminouracil from Saccharomyces cerevisiae | Descriptor: | 5-AMINO-1H-PYRIMIDINE-2,4-DIONE, Dihydroorotase, ZINC ION | Authors: | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | Deposit date: | 2019-09-26 | Release date: | 2020-12-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.26 Å) | Cite: | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
|
|
6L0K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6l0k by Molmil](/molmil-images/mine/6l0k) | Crystal structure of dihydroorotase in complex with malate at pH9 from Saccharomyces cerevisiae | Descriptor: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | Authors: | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | Deposit date: | 2019-09-26 | Release date: | 2020-12-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
|
|
6I5C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6i5c by Molmil](/molmil-images/mine/6i5c) | Long wavelength native-SAD phasing of Tubulin-Stathmin-TTL complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Basu, S, Olieric, V, Matsugaki, N, Kawano, Y, Takashi, T, Huang, C.Y, Leonarski, F, Yamada, Y, Vera, L, Olieric, N, Basquin, J, Wojdyla, J.A, Diederichs, K, Yamamoto, M, Bunk, O, Wang, M. | Deposit date: | 2018-11-13 | Release date: | 2019-03-13 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Long-wavelength native-SAD phasing: opportunities and challenges. Iucrj, 6, 2019
|
|
7CA0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ca0 by Molmil](/molmil-images/mine/7ca0) | Crystal structure of dihydroorotase in complex with 5-fluoroorotic acid from Saccharomyces cerevisiae | Descriptor: | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, ZINC ION | Authors: | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | Deposit date: | 2020-06-08 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Complexed Crystal Structure of Saccharomyces cerevisiae Dihydroorotase with Inhibitor 5-Fluoroorotate Reveals a New Binding Mode. Bioinorg Chem Appl, 2021, 2021
|
|
7CA1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ca1 by Molmil](/molmil-images/mine/7ca1) | Crystal structure of dihydroorotase in complex with plumbagin from Saccharomyces cerevisiae | Descriptor: | (2S)-2-hydroxybutanedioic acid, 5-hydroxy-2-methylnaphthalene-1,4-dione, Dihydroorotase, ... | Authors: | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | Deposit date: | 2020-06-08 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Plumbagin, a Natural Product with Potent Anticancer Activities, Binds to and Inhibits Dihydroorotase, a Key Enzyme in Pyrimidine Biosynthesis. Int J Mol Sci, 22, 2021
|
|
7F25
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7f25 by Molmil](/molmil-images/mine/7f25) | |
7F2N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7f2n by Molmil](/molmil-images/mine/7f2n) | |
7E3U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e3u by Molmil](/molmil-images/mine/7e3u) | Crystal structure of the Pseudomonas aeruginosa dihydropyrimidinase complexed with 5-AU | Descriptor: | 5-AMINO-1H-PYRIMIDINE-2,4-DIONE, D-hydantoinase/dihydropyrimidinase, ZINC ION | Authors: | Yang, Y.C, Luo, R.H, Huang, Y.H, Huang, C.Y, Lin, E.S. | Deposit date: | 2021-02-09 | Release date: | 2022-02-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.159 Å) | Cite: | Molecular Insights into How the Dimetal Center in Dihydropyrimidinase Can Bind the Thymine Antagonist 5-Aminouracil: A Different Binding Mode from the Anticancer Drug 5-Fluorouracil. Bioinorg Chem Appl, 2022, 2022
|
|
7DEP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dep by Molmil](/molmil-images/mine/7dep) | S. aureus SsbB with 5-FU | Descriptor: | 5-FLUOROURACIL, Single-stranded DNA-binding protein | Authors: | Lin, E.S, Huang, Y.H, Huang, C.Y. | Deposit date: | 2020-11-04 | Release date: | 2020-12-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.094 Å) | Cite: | Crystal structure of the single-stranded DNA-binding protein SsbB in complex with the anticancer drug 5-fluorouracil: Extension of the 5-fluorouracil interactome to include the oligonucleotide/oligosaccharide-binding fold protein Biochem.Biophys.Res.Commun., 534, 2020
|
|
7D8J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7d8j by Molmil](/molmil-images/mine/7d8j) | S. aureus SsbB with 5-FU | Descriptor: | 5-FLUOROURACIL, Single-stranded DNA-binding protein | Authors: | Lin, E.S, Huang, Y.H, Huang, C.Y. | Deposit date: | 2020-10-08 | Release date: | 2020-12-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Crystal structure of the single-stranded DNA-binding protein SsbB in complex with the anticancer drug 5-fluorouracil: Extension of the 5-fluorouracil interactome to include the oligonucleotide/oligosaccharide-binding fold protein Biochem.Biophys.Res.Commun., 534, 2020
|
|
7F2V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7f2v by Molmil](/molmil-images/mine/7f2v) | Urate oxidase from Thermobispora bispora in apo form | Descriptor: | DIMETHYL SULFOXIDE, SULFATE ION, Uricase | Authors: | Chiu, Y.C, Hsu, T.S, Huang, C.Y, Hsu, C.H. | Deposit date: | 2021-06-14 | Release date: | 2022-05-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural and biochemical insights into a hyperthermostable urate oxidase from Thermobispora bispora for hyperuricemia and gout therapy. Int.J.Biol.Macromol., 188, 2021
|
|
7F2W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7f2w by Molmil](/molmil-images/mine/7f2w) | TbUox in complex with uric acid | Descriptor: | URIC ACID, Uricase | Authors: | Chiu, Y.C, Hsu, T.S, Huang, C.Y, Hsu, C.H. | Deposit date: | 2021-06-14 | Release date: | 2022-05-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Structural and biochemical insights into a hyperthermostable urate oxidase from Thermobispora bispora for hyperuricemia and gout therapy. Int.J.Biol.Macromol., 188, 2021
|
|