6AEQ
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5YUN
| Crystal structure of SSB complexed with myc | 分子名称: | 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, Single-stranded DNA-binding protein | 著者 | Huang, Y.H, Huang, C.Y. | 登録日 | 2017-11-22 | 公開日 | 2018-10-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Crystal structure of SSB complexed with inhibitor myricetin. Biochem. Biophys. Res. Commun., 504, 2018
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7VUM
| Crystal structure of SSB complexed with que | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, Single-stranded DNA-binding protein | 著者 | Lin, E.S, Huang, Y.H, Huang, C.Y. | 登録日 | 2021-11-03 | 公開日 | 2022-03-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.319 Å) | 主引用文献 | A Complexed Crystal Structure of a Single-Stranded DNA-Binding Protein with Quercetin and the Structural Basis of Flavonol Inhibition Specificity. Int J Mol Sci, 23, 2022
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7L1E
| The Crystal Structure of Bromide-Bound GtACR1 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Anion channelrhodopsin-1, BROMIDE ION, ... | 著者 | Li, H, Huang, C.Y, Wang, M, Spudich, J.L, Zheng, L. | 登録日 | 2020-12-14 | 公開日 | 2021-05-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The crystal structure of bromide-bound Gt ACR1 reveals a pre-activated state in the transmembrane anion tunnel. Elife, 10, 2021
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6JDG
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6KLK
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6L0I
| Crystal structure of dihydroorotase in complex with malate at pH6.5 from Saccharomyces cerevisiae | 分子名称: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | 登録日 | 2019-09-26 | 公開日 | 2020-12-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
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6L0F
| Crystal structure of dihydroorotase in complex with 5-Aminouracil from Saccharomyces cerevisiae | 分子名称: | 5-AMINO-1H-PYRIMIDINE-2,4-DIONE, Dihydroorotase, ZINC ION | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | 登録日 | 2019-09-26 | 公開日 | 2020-12-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.26 Å) | 主引用文献 | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
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6L0K
| Crystal structure of dihydroorotase in complex with malate at pH9 from Saccharomyces cerevisiae | 分子名称: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | 登録日 | 2019-09-26 | 公開日 | 2020-12-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
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6L0J
| Crystal structure of Dihydroorotase in complex with malate at pH7.5 from Saccharomyces cerevisiae | 分子名称: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | 登録日 | 2019-09-26 | 公開日 | 2020-12-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.933 Å) | 主引用文献 | Structural Analysis of Saccharomyces cerevisiae Dihydroorotase Reveals Molecular Insights into the Tetramerization Mechanism Molecules, 2021
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6L0H
| Crystal structure of dihydroorotase in complex with malate at pH7 from Saccharomyces cerevisiae | 分子名称: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | 登録日 | 2019-09-26 | 公開日 | 2020-12-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.054 Å) | 主引用文献 | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
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6L0B
| Crystal structure of dihydroorotase in complex with fluorouracil from Saccharomyces cerevisiae | 分子名称: | 5-FLUOROURACIL, Dihydroorotase, ZINC ION | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | 登録日 | 2019-09-26 | 公開日 | 2020-12-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
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6L0G
| Crystal structure of dihydroorotase in complex with malate at pH6 from Saccharomyces cerevisiae | 分子名称: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | 登録日 | 2019-09-26 | 公開日 | 2020-12-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.053 Å) | 主引用文献 | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
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6L0A
| Crystal structure of dihydroorotase in complex with malate at pH7 from Saccharomyces cerevisiae | 分子名称: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | 登録日 | 2019-09-26 | 公開日 | 2020-12-02 | 最終更新日 | 2021-12-15 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Structural Analysis of Saccharomyces cerevisiae Dihydroorotase Reveals Molecular Insights into the Tetramerization Mechanism Molecules, 2021
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7CA0
| Crystal structure of dihydroorotase in complex with 5-fluoroorotic acid from Saccharomyces cerevisiae | 分子名称: | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, ZINC ION | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | 登録日 | 2020-06-08 | 公開日 | 2021-06-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Complexed Crystal Structure of Saccharomyces cerevisiae Dihydroorotase with Inhibitor 5-Fluoroorotate Reveals a New Binding Mode. Bioinorg Chem Appl, 2021, 2021
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7CA1
| Crystal structure of dihydroorotase in complex with plumbagin from Saccharomyces cerevisiae | 分子名称: | (2S)-2-hydroxybutanedioic acid, 5-hydroxy-2-methylnaphthalene-1,4-dione, Dihydroorotase, ... | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | 登録日 | 2020-06-08 | 公開日 | 2021-06-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Plumbagin, a Natural Product with Potent Anticancer Activities, Binds to and Inhibits Dihydroorotase, a Key Enzyme in Pyrimidine Biosynthesis. Int J Mol Sci, 22, 2021
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7F2N
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7DEP
| S. aureus SsbB with 5-FU | 分子名称: | 5-FLUOROURACIL, Single-stranded DNA-binding protein | 著者 | Lin, E.S, Huang, Y.H, Huang, C.Y. | 登録日 | 2020-11-04 | 公開日 | 2020-12-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.094 Å) | 主引用文献 | Crystal structure of the single-stranded DNA-binding protein SsbB in complex with the anticancer drug 5-fluorouracil: Extension of the 5-fluorouracil interactome to include the oligonucleotide/oligosaccharide-binding fold protein Biochem.Biophys.Res.Commun., 534, 2020
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7E3U
| Crystal structure of the Pseudomonas aeruginosa dihydropyrimidinase complexed with 5-AU | 分子名称: | 5-AMINO-1H-PYRIMIDINE-2,4-DIONE, D-hydantoinase/dihydropyrimidinase, ZINC ION | 著者 | Yang, Y.C, Luo, R.H, Huang, Y.H, Huang, C.Y, Lin, E.S. | 登録日 | 2021-02-09 | 公開日 | 2022-02-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.159 Å) | 主引用文献 | Molecular Insights into How the Dimetal Center in Dihydropyrimidinase Can Bind the Thymine Antagonist 5-Aminouracil: A Different Binding Mode from the Anticancer Drug 5-Fluorouracil. Bioinorg Chem Appl, 2022, 2022
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7D8J
| S. aureus SsbB with 5-FU | 分子名称: | 5-FLUOROURACIL, Single-stranded DNA-binding protein | 著者 | Lin, E.S, Huang, Y.H, Huang, C.Y. | 登録日 | 2020-10-08 | 公開日 | 2020-12-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | Crystal structure of the single-stranded DNA-binding protein SsbB in complex with the anticancer drug 5-fluorouracil: Extension of the 5-fluorouracil interactome to include the oligonucleotide/oligosaccharide-binding fold protein Biochem.Biophys.Res.Commun., 534, 2020
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7BET
| Structure of Ribonucleotide reductase R2 from Escherichia coli collected by femtosecond serial crystallography on a COC membrane | 分子名称: | FE (III) ION, Ribonucleoside-diphosphate reductase 1 subunit beta | 著者 | Aurelius, O, John, J, Martiel, I, Marsh, M, Vera, L, Huang, C.Y, Olieric, V, Leonarski, P, Nass, K, Padeste, C, Karpik, A, Hogbom, M, Wang, M, Pedrini, B. | 登録日 | 2020-12-24 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Commissioning results from the SwissMX instrument for fixed target macromolecular crystallography at SwissFEL To Be Published
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6J0I
| Structure of [Co2+-(Chromomycin A3)2]-d(TTGGCGAA)2 complex | 分子名称: | 1,2-HYDRO-1-OXY-3,4-HYDRO-3-(1-METHOXY-2-OXY-3,4-DIHYDROXYPENTYL)-8,9-DIHYROXY-7-METHYLANTHRACENE, 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose-(1-3)-(2R,3R,6R)-6-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate, 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol, ... | 著者 | Satange, R.B, Chuang, C.Y, Hou, M.H. | 登録日 | 2018-12-24 | 公開日 | 2019-07-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Polymorphic G:G mismatches act as hotspots for inducing right-handed Z DNA by DNA intercalation. Nucleic Acids Res., 47, 2019
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