1LGD
 
 | | Crystal Structure Analysis of HCA II Mutant T199P in Complex with Bicarbonate | | Descriptor: | BICARBONATE ION, Carbonic anhydrase II, ZINC ION | | Authors: | Huang, S, Sjoblom, B, Sauer-Eriksson, A.E, Jonsson, B.-H. | | Deposit date: | 2002-04-15 | | Release date: | 2002-07-24 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Organization of an efficient carbonic anhydrase: implications for the mechanism based on structure-function studies of a T199P/C206S mutant.
Biochemistry, 41, 2002
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8JPT
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8JOH
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1LG5
 | | Crystal Structure Analysis of the HCA II Mutant T199P in complex with beta-mercaptoethanol | | Descriptor: | BETA-MERCAPTOETHANOL, Carbonic anhydrase II, ZINC ION | | Authors: | Huang, S, Sjoblom, B, Sauer-Eriksson, A.E, Jonsson, B.-H. | | Deposit date: | 2002-04-15 | | Release date: | 2002-07-24 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Organization of an efficient carbonic anhydrase: implications for the mechanism based on structure-function studies of a T199P/C206S mutant.
Biochemistry, 41, 2002
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1LG6
 | | Crystal Structure Analysis of HCA II Mutant T199P in Complex with Thiocyanate | | Descriptor: | Carbonic anhydrase II, THIOCYANATE ION, ZINC ION | | Authors: | Huang, S, Sjoblom, B, Sauer-Eriksson, A.E, Jonsson, B.-H. | | Deposit date: | 2002-04-15 | | Release date: | 2002-07-24 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Organization of an efficient carbonic anhydrase: implications for the mechanism based on structure-function studies of a T199P/C206S mutant.
Biochemistry, 41, 2002
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8UX1
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8JPU
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8W7W
 | | Crystal structure of d(CGTATACG)2 with acridine complex | | Descriptor: | DNA (5'-D(P*CP*GP*TP*AP*TP*AP*CP*G)-3'), MAGNESIUM ION, ~{N},~{N}'-di(acridin-9-yl)pentane-1,5-diamine | | Authors: | Huang, S.C, Satange, R.B, Hou, M.H. | | Deposit date: | 2023-08-31 | | Release date: | 2024-08-07 | | Last modified: | 2024-09-11 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Targeting DNA junction sites by bis-intercalators induces topological changes with potent antitumor effects.
Nucleic Acids Res., 52, 2024
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8WQ7
 | | Crystal structure of d(CGTATACG)2 with a four-carbon linker containing diacridine compound | | Descriptor: | DNA (5'-D(P*CP*GP*TP*AP*TP*AP*CP*G)-3'), MANGANESE (II) ION, N,N'-di(acridin-9-yl)butane-1,4-diamine | | Authors: | Huang, S.C, Satange, R.B, Hou, M.H. | | Deposit date: | 2023-10-11 | | Release date: | 2024-08-07 | | Last modified: | 2024-09-11 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Targeting DNA junction sites by bis-intercalators induces topological changes with potent antitumor effects.
Nucleic Acids Res., 52, 2024
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2MVW
 | | Solution structure of the TRIM19 B-box1 (B1) of human promyelocytic leukemia (PML) | | Descriptor: | Protein PML, ZINC ION | | Authors: | Huang, S, Naik, M.T, Fan, P, Wang, Y, Chang, C, Huang, T. | | Deposit date: | 2014-10-17 | | Release date: | 2014-11-12 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The B-box 1 dimer of human promyelocytic leukemia protein.
J.Biomol.Nmr, 60, 2014
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3UCO
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3UCN
 | | Coccomyxa beta-carbonic anhydrase in complex with azide | | Descriptor: | AZIDE ION, CHLORIDE ION, Carbonic anhydrase, ... | | Authors: | Huang, S, Hainzl, T, Sauer-Eriksson, A.E. | | Deposit date: | 2011-10-27 | | Release date: | 2011-11-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural studies of [beta]-carbonic anhydrase from the green alga Coccomyxa: inhibitor complexes with anions and acetazolamide.
Plos One, 6, 2011
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7YHE
 | | Crystal structure of the triple mutant CmnC-L136Q,S138G,D249Y in complex with alpha-KG | | Descriptor: | 2-OXOGLUTARIC ACID, CmnC, FE (III) ION, ... | | Authors: | Huang, S.J, Hsiao, Y.H, Lin, E.C, Hsiao, P.Y, Chang, C.Y. | | Deposit date: | 2022-07-13 | | Release date: | 2023-07-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
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7YW9
 | | Crystal structure of the triple mutant CmnC-L136Q,S138G,D249Y in complex with alpha-KG | | Descriptor: | ACETATE ION, CmnC, D-ARGININE, ... | | Authors: | Huang, S.J, Hsiao, Y.H, Lin, E.C, Hsiao, P.Y, Chang, C.Y. | | Deposit date: | 2022-08-22 | | Release date: | 2023-08-30 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
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1KOQ
 | | NEISSERIA GONORRHOEAE CARBONIC ANHYDRASE | | Descriptor: | CARBONIC ANHYDRASE, ZINC ION | | Authors: | Huang, S, Xue, Y, Chirica, L, Lindskog, S, Jonsson, B.-H. | | Deposit date: | 1998-03-22 | | Release date: | 1998-12-09 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of carbonic anhydrase from Neisseria gonorrhoeae and its complex with the inhibitor acetazolamide.
J.Mol.Biol., 283, 1998
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3UCJ
 | | Coccomyxa beta-carbonic anhydrase in complex with acetazolamide | | Descriptor: | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, CHLORIDE ION, Carbonic anhydrase, ... | | Authors: | Huang, S, Hainzl, T, Sauer-Eriksson, A.E. | | Deposit date: | 2011-10-27 | | Release date: | 2011-11-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural studies of [beta]-carbonic anhydrase from the green alga Coccomyxa: inhibitor complexes with anions and acetazolamide.
Plos One, 6, 2011
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3UCK
 | | Coccomyxa beta-carbonic anhydrase in complex with phosphate | | Descriptor: | CHLORIDE ION, Carbonic anhydrase, PHOSPHATE ION, ... | | Authors: | Huang, S, Hainzl, T, Sauer-Eriksson, A.E. | | Deposit date: | 2011-10-27 | | Release date: | 2011-11-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural studies of [beta]-carbonic anhydrase from the green alga Coccomyxa: inhibitor complexes with anions and acetazolamide.
Plos One, 6, 2011
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2MWX
 | | The RING Domain of human Promyelocytic Leukemia Protein (PML) | | Descriptor: | Protein PML, ZINC ION | | Authors: | Huang, S.Y, Chang, C.F, Fan, P.J, Guntert, P, Shih, H.M, Huang, T.H. | | Deposit date: | 2014-12-02 | | Release date: | 2015-02-11 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The RING domain of human promyelocytic leukemia protein (PML).
J.Biomol.Nmr, 61, 2015
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4ESX
 | | Crystal structure of C. albicans Thi5 complexed with PLP | | Descriptor: | Pyrimidine biosynthesis enzyme THI13 | | Authors: | Huang, S, Fenwick, M.K, Zhang, Y, Lai, R, Hazra, A, Rajashankar, K, Philmus, B, Kinsland, C, Sanders, J, Begley, T.P, Ealick, S.E. | | Deposit date: | 2012-04-23 | | Release date: | 2012-09-19 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate.
J.Am.Chem.Soc., 134, 2012
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5GPE
 | | Crystal structure of the transcription regulator PbrR691 from Ralstonia metallidurans CH34 in complex with Lead(II) | | Descriptor: | LEAD (II) ION, Transcriptional regulator, MerR-family | | Authors: | Huang, S.Q, Chen, W.Z, Wang, D, Hu, Q.Y, Liu, X.C, Gan, J.H, Chen, H. | | Deposit date: | 2016-08-01 | | Release date: | 2016-12-28 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Structural Basis for the Selective Pb(II) Recognition of Metalloregulatory Protein PbrR691
Inorg Chem, 55, 2016
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1KOP
 | | NEISSERIA GONORRHOEAE CARBONIC ANHYDRASE | | Descriptor: | AZIDE ION, BETA-MERCAPTOETHANOL, CARBONIC ANHYDRASE, ... | | Authors: | Huang, S, Xue, Y, Chirica, L, Lindskog, S, Jonsson, B.-H. | | Deposit date: | 1998-03-22 | | Release date: | 1998-12-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of carbonic anhydrase from Neisseria gonorrhoeae and its complex with the inhibitor acetazolamide.
J.Mol.Biol., 283, 1998
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8IA9
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3UCM
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1M3W
 | | Crystal Structure of a Molecular Maquette Scaffold | | Descriptor: | H10H24, MERCURY (II) ION | | Authors: | Huang, S.S, Gibney, B.R, Stayrook, S.E, Dutton, P.L, Lewis, M. | | Deposit date: | 2002-07-01 | | Release date: | 2003-02-18 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | X-ray Structure of a Maquette Scaffold
J.Mol.Biol., 326, 2003
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4GIL
 | | Crystal Structure of Pseudouridine Monophosphate Glycosidase/Linear Pseudouridine 5'-Phosphate Adduct | | Descriptor: | MANGANESE (II) ION, Pseudouridine-5'-phosphate glycosidase, pseudouridine 5'-phosphate, ... | | Authors: | Huang, S, Mahanta, N, Begley, T.P, Ealick, S.E. | | Deposit date: | 2012-08-08 | | Release date: | 2012-10-31 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.539 Å) | | Cite: | Pseudouridine monophosphate glycosidase: a new glycosidase mechanism.
Biochemistry, 51, 2012
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