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PDB: 200 件

8H34
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Cryo-EM Structure of the KBTBD2-Cul3-Rbx1 hexameric complex
分子名称: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch repeat and BTB domain-containing protein 2, ...
著者Hu, Y, Mao, Q, Chen, Z, Sun, L.
登録日2022-10-07
公開日2023-10-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7.99 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
8H33
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Cryo-EM Structure of the KBTBD2-Cul3-Rbx1 tetrameric complex
分子名称: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch repeat and BTB domain-containing protein 2, ...
著者Hu, Y, Mao, Q, Chen, Z, Sun, L.
登録日2022-10-07
公開日2023-10-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7.86 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
8H3Q
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Cryo-EM Structure of the CAND1-Cul3-Rbx1 complex
分子名称: Cullin-3, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
著者Hu, Y, Mao, Q, Chen, Z, Sun, L.
登録日2022-10-09
公開日2023-10-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
8H3A
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Cryo-EM Structure of the KBTBD2-CRL3~N8(removed)-CSN complex
分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
著者Hu, Y, Mao, Q, Chen, Z, Sun, L.
登録日2022-10-08
公開日2023-10-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7.51 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
8H3F
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Cryo-EM Structure of the KBTBD2-CRL3-CSN complex
分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
著者Hu, Y, Mao, Q, Chen, Z, Sun, L.
登録日2022-10-08
公開日2023-10-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (6.73 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
6KQW
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Crystal structure of Yijc from B. subtilis
分子名称: CITRIC ACID, Uncharacterized UDP-glucosyltransferase YjiC
著者Hu, Y.M, Dai, L.H, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T.
登録日2019-08-20
公開日2020-09-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structural dissection of unnatural ginsenoside-biosynthetic UDP-glycosyltransferase Bs-YjiC from Bacillus subtilis for substrate promiscuity.
Biochem.Biophys.Res.Commun., 534, 2021
6LW3
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Crystal structure of RuvC from Pseudomonas aeruginosa
分子名称: Crossover junction endodeoxyribonuclease RuvC
著者Hu, Y, He, Y, Lin, Z.
登録日2020-02-07
公開日2020-02-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Biochemical and structural characterization of the Holliday junction resolvase RuvC from Pseudomonas aeruginosa.
Biochem.Biophys.Res.Commun., 525, 2020
2VHA
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DEBP
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLUTAMIC ACID, PERIPLASMIC BINDING TRANSPORT PROTEIN
著者Hu, Y.L, Fan, C.-P, Fu, G.S, Zhu, D.Y, Jin, Q, Wang, D.-C.
登録日2007-11-20
公開日2008-07-08
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Crystal Structure of a Glutamate/Aspartate Binding Protein Complexed with a Glutamate Molecule: Structural Basis of Ligand Specificity at Atomic Resolution.
J.Mol.Biol., 382, 2008
4XLY
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The complex structure of KS-D75C with substrate CPP
分子名称: (2E)-3-methyl-5-[(1R,4aR,8aR)-5,5,8a-trimethyl-2-methylidenedecahydronaphthalen-1-yl]pent-2-en-1-yl trihydrogen diphosphate, Uncharacterized protein blr2150
著者Hu, Y, Zheng, Y, Ko, T.P, Liu, W, Guo, R.T.
登録日2015-01-14
公開日2015-02-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum.
Sci Rep, 4, 2014
4XLX
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Crystal structure of BjKS from Bradyrhizobium japonicum
分子名称: Uncharacterized protein blr2150
著者Hu, Y, Zheng, Y, Ko, T.P, Liu, W, Guo, R.T.
登録日2015-01-14
公開日2015-02-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum.
Sci Rep, 4, 2014
4W98
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Acinetobacter baumannii SDF NDK
分子名称: Nucleoside diphosphate kinase
著者Hu, Y, Feng, F, Liang, H, Liu, Y.
登録日2014-08-27
公開日2015-06-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Structural and Functional Characterization of Acinetobacter baumannii Nucleoside Diphosphate Kinase
Prog.Biochem.Biophys., 42, 2015
4TQM
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Structural basis of specific recognition of non-reducing terminal N-acetylglucosamine by an Agrocybe aegerita lection
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lectin 2
著者Hu, Y.L, Ren, X.M, Li, D.F, Jiang, S, Lan, X.Q, Sun, H, Wang, D.C.
登録日2014-06-11
公開日2015-06-03
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis of Specific Recognition of Non-Reducing Terminal N-Acetylglucosamine by an Agrocybe aegerita Lectin.
Plos One, 10, 2015
4WBF
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Acinetobacter baumannii SDF NDK
分子名称: Nucleoside diphosphate kinase
著者Hu, Y, Liu, Y.
登録日2014-09-03
公開日2015-06-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structural and Functional Characterization of Acinetobacter baumannii Nucleoside Diphosphate Kinase
Prog.Biochem.Biophys., 42, 2015
8DZH
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BU of 8dzh by Molmil
Structure of SARS-CoV-2 Omicron BA.1.1.529 Spike trimer with two RBDs down in complex with the Fab fragment of human neutralizing antibody MB.02
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Hu, Y, Xiong, Y.
登録日2022-08-07
公開日2022-08-31
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Function and Cryo-EM structures of broadly potent bispecific antibodies against multiple SARS-CoV-2 Omicron sublineages.
Signal Transduct Target Ther, 8, 2023
8DZI
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Structure of SARS-CoV-2 Omicron BA.1.1.529 Spike trimer with one RBD down in complex with the Fab fragment of human neutralizing antibody MB.02
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Hu, Y, Xiong, Y.
登録日2022-08-07
公開日2022-08-31
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Function and Cryo-EM structures of broadly potent bispecific antibodies against multiple SARS-CoV-2 Omicron sublineages.
Signal Transduct Target Ther, 8, 2023
1NLM
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BU of 1nlm by Molmil
CRYSTAL STRUCTURE OF MURG:GLCNAC COMPLEX
分子名称: GLYCEROL, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
著者Hu, Y, Chen, L, Ha, S, Gross, B, Falcone, B, Walker, D, Mokhtarzadeh, M, Walker, S.
登録日2003-01-07
公開日2003-02-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of MurG:UDP-GlcNAc complex reveals common structural principles of a superfamily of glycosyltransferases
Proc.Natl.Acad.Sci.USA, 100, 2003
1ZLG
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BU of 1zlg by Molmil
Solution structure of the extracellular matrix protein anosmin-1
分子名称: Anosmin 1
著者Hu, Y, Sun, Z, Eaton, J.T, Bouloux, P.M, Perkins, S.J.
登録日2005-05-06
公開日2006-05-09
最終更新日2024-05-22
実験手法SOLUTION SCATTERING
主引用文献Extended and Flexible Domain Solution Structure of the Extracellular Matrix Protein Anosmin-1 by X-ray Scattering, Analytical Ultracentrifugation and Constrained Modelling.
J.Mol.Biol., 350, 2005
1WOD
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CRYSTAL STRUCTURE OF MODA, A MOLYBDATE PROTEIN, COMPLEXED WITH TUNGSTATE
分子名称: MODA, TUNGSTATE(VI)ION
著者Hu, Y, Rech, S, Gunsalus, R.P, Rees, D.C.
登録日1997-06-17
公開日1997-12-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of the molybdate binding protein ModA.
Nat.Struct.Biol., 4, 1997
7MW3
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Structure of the SARS-CoV-2 Spike trimer with two RBDs down in complex with the Fab fragment of human neutralizing antibody clone 6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hu, Y, Xiong, Y.
登録日2021-05-15
公開日2022-03-16
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617.
Nat Commun, 13, 2022
7MW4
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Structure of the SARS-CoV-2 Spike trimer with one RBD down in complex with the Fab fragment of human neutralizing antibody clone 6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hu, Y, Xiong, Y.
登録日2021-05-15
公開日2022-03-16
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617.
Nat Commun, 13, 2022
7MW6
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Structure of the SARS-CoV-2 Spike trimer with three RBDs up in complex with the Fab fragment of human neutralizing antibody clone 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hu, Y, Xiong, Y.
登録日2021-05-15
公開日2022-03-16
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617.
Nat Commun, 13, 2022
7MW5
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BU of 7mw5 by Molmil
Structure of the SARS-CoV-2 Spike trimer with one RBD down in complex with the Fab fragment of human neutralizing antibody clone 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab of antibody clone 2, ...
著者Hu, Y, Xiong, Y.
登録日2021-05-15
公開日2022-03-16
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617.
Nat Commun, 13, 2022
7MW2
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Structure of the SARS-CoV-2 Spike trimer with all RBDs down in complex with the Fab fragment of human neutralizing antibody clone 6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab of antibody clone 6, ...
著者Hu, Y, Xiong, Y.
登録日2021-05-15
公開日2022-03-16
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617.
Nat Commun, 13, 2022
8H38
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Cryo-EM Structure of the KBTBD2-CRL3~N8-CSN(mutate) complex
分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
著者Hu, Y, Mao, Q, Chen, Z, Sun, L.
登録日2022-10-08
公開日2023-10-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
8H37
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Cryo-EM Structure of the KBTBD2-CUL3-Rbx1-p85a tetrameric complex
分子名称: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch repeat and BTB domain-containing protein 2, ...
著者Hu, Y, Mao, Q, Chen, Z, Sun, L.
登録日2022-10-08
公開日2023-10-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7.52 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024

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