7F63
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![BU of 7f63 by Molmil](/molmil-images/mine/7f63) | Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody chAb-45 (Focused refinement of S-RBD and chAb-45 region) | Descriptor: | RBD-chAb45, Heavy chain, Light chain, ... | Authors: | Yang, T.J, Yu, P.Y, Wu, H.C, Hsu, S.T.D. | Deposit date: | 2021-06-24 | Release date: | 2021-08-04 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure-guided antibody cocktail for prevention and treatment of COVID-19. Plos Pathog., 17, 2021
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7F62
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![BU of 7f62 by Molmil](/molmil-images/mine/7f62) | Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody chAb-25 (Focused refinement of S-RBD and chAb-25 region) | Descriptor: | RBD-chAb-25, Heavy chain, Light chain, ... | Authors: | Yang, T.J, Yu, P.Y, Wu, H.C, Hsu, S.T.D. | Deposit date: | 2021-06-24 | Release date: | 2021-08-04 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure-guided antibody cocktail for prevention and treatment of COVID-19. Plos Pathog., 17, 2021
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7VPW
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![BU of 7vpw by Molmil](/molmil-images/mine/7vpw) | |
7EDJ
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![BU of 7edj by Molmil](/molmil-images/mine/7edj) | Cryo-EM structure of SARS-CoV-2 S-UK variant (B.1.1.7) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2 (ACE2) ectodomain, ... | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Wu, H.C, Hsu, S.T.D. | Deposit date: | 2021-03-16 | Release date: | 2021-09-01 | Last modified: | 2022-01-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Effect of SARS-CoV-2 B.1.1.7 mutations on spike protein structure and function. Nat.Struct.Mol.Biol., 28, 2021
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7EDI
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![BU of 7edi by Molmil](/molmil-images/mine/7edi) | Cryo-EM structure of SARS-CoV-2 S-UK variant (B.1.1.7), two RBD-up conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Wu, H.C, Hsu, S.T.D. | Deposit date: | 2021-03-16 | Release date: | 2021-09-01 | Last modified: | 2022-01-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Effect of SARS-CoV-2 B.1.1.7 mutations on spike protein structure and function. Nat.Struct.Mol.Biol., 28, 2021
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7EDH
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![BU of 7edh by Molmil](/molmil-images/mine/7edh) | Cryo-EM structure of SARS-CoV-2 S-UK variant (B.1.1.7), one RBD-up conformation 3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Wu, H.C, Hsu, S.T.D. | Deposit date: | 2021-03-16 | Release date: | 2021-09-01 | Last modified: | 2022-01-05 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Effect of SARS-CoV-2 B.1.1.7 mutations on spike protein structure and function. Nat.Struct.Mol.Biol., 28, 2021
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7EDF
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![BU of 7edf by Molmil](/molmil-images/mine/7edf) | Cryo-EM structure of SARS-CoV-2 S-UK variant (B.1.1.7), one RBD-up conformation 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Wu, H.C, Hsu, S.T.D. | Deposit date: | 2021-03-16 | Release date: | 2021-09-01 | Last modified: | 2022-01-05 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Effect of SARS-CoV-2 B.1.1.7 mutations on spike protein structure and function. Nat.Struct.Mol.Biol., 28, 2021
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7EDG
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![BU of 7edg by Molmil](/molmil-images/mine/7edg) | Cryo-EM structure of SARS-CoV-2 S-UK variant (B.1.1.7), one RBD-up conformation 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Wu, H.C, Hsu, S.T.D. | Deposit date: | 2021-03-16 | Release date: | 2021-09-01 | Last modified: | 2022-01-05 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Effect of SARS-CoV-2 B.1.1.7 mutations on spike protein structure and function. Nat.Struct.Mol.Biol., 28, 2021
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7EH5
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![BU of 7eh5 by Molmil](/molmil-images/mine/7eh5) | Cryo-EM structure of SARS-CoV-2 S-D614G variant in complex with neutralizing antibodies, RBD-chAb15 and RBD-chAb45 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RBD-chAb15, ... | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Wu, H.C, Hsu, S.T.D. | Deposit date: | 2021-03-28 | Release date: | 2021-09-01 | Last modified: | 2022-01-05 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Effect of SARS-CoV-2 B.1.1.7 mutations on spike protein structure and function. Nat.Struct.Mol.Biol., 28, 2021
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7EB0
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![BU of 7eb0 by Molmil](/molmil-images/mine/7eb0) | Cryo-EM structure of SARS-CoV-2 Spike D614G variant, one RBD-up conformation 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D. | Deposit date: | 2021-03-08 | Release date: | 2021-06-23 | Last modified: | 2022-01-05 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | D614G mutation in the SARS-CoV-2 spike protein enhances viral fitness by desensitizing it to temperature-dependent denaturation. J.Biol.Chem., 297, 2021
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7EAZ
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![BU of 7eaz by Molmil](/molmil-images/mine/7eaz) | Cryo-EM structure of SARS-CoV-2 Spike D614G variant, one RBD-up conformation 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D. | Deposit date: | 2021-03-08 | Release date: | 2021-06-23 | Last modified: | 2022-01-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | D614G mutation in the SARS-CoV-2 spike protein enhances viral fitness by desensitizing it to temperature-dependent denaturation. J.Biol.Chem., 297, 2021
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7EB5
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![BU of 7eb5 by Molmil](/molmil-images/mine/7eb5) | Cryo-EM structure of SARS-CoV-2 Spike D614G variant, two RBD-up conformation 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D. | Deposit date: | 2021-03-08 | Release date: | 2021-06-23 | Last modified: | 2022-01-05 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | D614G mutation in the SARS-CoV-2 spike protein enhances viral fitness by desensitizing it to temperature-dependent denaturation. J.Biol.Chem., 297, 2021
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7EB3
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![BU of 7eb3 by Molmil](/molmil-images/mine/7eb3) | Cryo-EM structure of SARS-CoV-2 Spike D614G variant, one RBD-up conformation 3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D. | Deposit date: | 2021-03-08 | Release date: | 2021-06-23 | Last modified: | 2022-01-05 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | D614G mutation in the SARS-CoV-2 spike protein enhances viral fitness by desensitizing it to temperature-dependent denaturation. J.Biol.Chem., 297, 2021
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7EB4
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![BU of 7eb4 by Molmil](/molmil-images/mine/7eb4) | Cryo-EM structure of SARS-CoV-2 Spike D614G variant, two RBD-up conformation 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D. | Deposit date: | 2021-03-08 | Release date: | 2021-06-23 | Last modified: | 2022-01-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | D614G mutation in the SARS-CoV-2 spike protein enhances viral fitness by desensitizing it to temperature-dependent denaturation. J.Biol.Chem., 297, 2021
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7F5N
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![BU of 7f5n by Molmil](/molmil-images/mine/7f5n) | Crystal structure of TCPTP catalytic domain | Descriptor: | Tyrosine-protein phosphatase non-receptor type 2 | Authors: | Singh, J.P, Lin, M.-J, Hsu, S.-F, Lee, C.-C, Meng, T.-C. | Deposit date: | 2021-06-22 | Release date: | 2021-12-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Crystal Structure of TCPTP Unravels an Allosteric Regulatory Role of Helix alpha 7 in Phosphatase Activity. Biochemistry, 60, 2021
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7F5O
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![BU of 7f5o by Molmil](/molmil-images/mine/7f5o) | Crystal structure of PTPN2 catalytic domain | Descriptor: | IODIDE ION, Tyrosine-protein phosphatase non-receptor type 2 | Authors: | Singh, J.P, Lin, M.-J, Hsu, S.-F, Lee, C.-C, Meng, T.-C. | Deposit date: | 2021-06-22 | Release date: | 2021-12-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of TCPTP Unravels an Allosteric Regulatory Role of Helix alpha 7 in Phosphatase Activity. Biochemistry, 60, 2021
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7V7J
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![BU of 7v7j by Molmil](/molmil-images/mine/7v7j) | Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), dimer of S trimer conformation 3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D. | Deposit date: | 2021-08-21 | Release date: | 2021-10-06 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), dimer of S trimer conformation 3 To Be Published
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7V7H
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![BU of 7v7h by Molmil](/molmil-images/mine/7v7h) | Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), dimer of S trimer conformation 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D. | Deposit date: | 2021-08-21 | Release date: | 2021-10-06 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), dimer of S trimer conformation 1 To Be Published
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7V7I
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![BU of 7v7i by Molmil](/molmil-images/mine/7v7i) | Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), dimer of S trimer conformation 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D. | Deposit date: | 2021-08-21 | Release date: | 2021-10-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), dimer of S trimer conformation 2 To Be Published
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7CXS
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![BU of 7cxs by Molmil](/molmil-images/mine/7cxs) | |
7CXV
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![BU of 7cxv by Molmil](/molmil-images/mine/7cxv) | Crystal structure of CmnK | Descriptor: | CmnK | Authors: | Chang, C.Y, Hsu, S.H. | Deposit date: | 2020-09-02 | Release date: | 2021-07-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Characterization of Enzymes Catalyzing the Formation of the Nonproteinogenic Amino Acid l-Dap in Capreomycin Biosynthesis. Biochemistry, 60, 2021
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7CXU
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![BU of 7cxu by Molmil](/molmil-images/mine/7cxu) | Crystal structure of CmnK in complex with NAD+ | Descriptor: | CmnK, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Chang, C.Y, Hsu, S.H. | Deposit date: | 2020-09-02 | Release date: | 2021-07-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Characterization of Enzymes Catalyzing the Formation of the Nonproteinogenic Amino Acid l-Dap in Capreomycin Biosynthesis. Biochemistry, 60, 2021
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7V76
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![BU of 7v76 by Molmil](/molmil-images/mine/7v76) | Cryo-EM structure of SARS-CoV-2 S-Beta variant (B.1.351), uncleavable form, one RBD-up conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D. | Deposit date: | 2021-08-21 | Release date: | 2021-10-06 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of SARS-CoV-2 S-Beta variant (B.1.351), uncleavable form, one RBD-up conformation To Be Published
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7V7T
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![BU of 7v7t by Molmil](/molmil-images/mine/7v7t) | Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), two RBD-up conformation 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D. | Deposit date: | 2021-08-21 | Release date: | 2021-10-06 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), two RBD-up conformation 1 To Be Published
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7V7Z
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![BU of 7v7z by Molmil](/molmil-images/mine/7v7z) | Cryo-EM structure of SARS-CoV-2 S-Beta variant (B.1.351) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2,Green fluorescent protein, ... | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D. | Deposit date: | 2021-08-22 | Release date: | 2021-10-06 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structure of SARS-CoV-2 S-Beta variant (B.1.351) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form To Be Published
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