7F63

Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody chAb-45 (Focused refinement of S-RBD and chAb-45 region)

Summary for 7F63

• Entry DOI: 10.2210/pdb7f63/pdb
• Related: 7EJ5
• EMDB information: 30670 31471
• Descriptor: Spike glycoprotein, RBD-chAb45, Heavy chain, RBD-chAb45, Light chain (3 entities in total)
• Functional Keywords: sars-cov-2, spike protein, neutralizing antibody, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 3
• Total formula weight: 215170.65

Authors

Yang, T.J.,Yu, P.Y.,Wu, H.C.,Hsu, S.T.D. (deposition date: 2021-06-24, release date: 2021-08-04, Last modification date: 2022-02-16)

• Primary citation: Su, S.C.,Yang, T.J.,Yu, P.Y.,Liang, K.H.,Chen, W.Y.,Yang, C.W.,Lin, H.T.,Wang, M.J.,Lu, R.M.,Tso, H.C.,Chung, M.J.,Hsieh, T.Y.,Chang, Y.L.,Lin, S.C.,Hsu, F.Y.,Ke, F.Y.,Wu, Y.H.,Hwang, Y.C.,Liu, I.J.,Liang, J.J.,Liao, C.C.,Ko, H.Y.,Sun, C.P.,Wu, P.Y.,Jan, J.T.,Chang, Y.C.,Lin, Y.L.,Tao, M.H.,Hsu, S.D.,Wu, H.C.; Structure-guided antibody cocktail for prevention and treatment of COVID-19.; Plos Pathog., 17:e1009704-e1009704, 2021; PubMed: 34673836; DOI: 10.1371/journal.ppat.1009704

Experimental method

ELECTRON MICROSCOPY (3.9 Å)