6IXJ
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![BU of 6ixj by Molmil](/molmil-images/mine/6ixj) | The crystal structure of sulfoacetaldehyde reductase from Klebsiella oxytoca | 分子名称: | 2-hydroxyethylsulfonic acid, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Sulfoacetaldehyde reductase | 著者 | Zhou, Y, Xu, T, Lin, L, Zhang, Y, Yuchi, Z. | 登録日 | 2018-12-10 | 公開日 | 2019-02-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Biochemical and structural investigation of sulfoacetaldehyde reductase fromKlebsiella oxytoca. Biochem. J., 476, 2019
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2K74
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![BU of 2k74 by Molmil](/molmil-images/mine/2k74) | Solution NMR structure of DsbB-ubiquinone complex | 分子名称: | Disulfide bond formation protein B, UBIQUINONE-2 | 著者 | Zhou, Y, Cierpicki, T, Flores Jimenez, R.H, Lukasik, S.M, Ellena, J.F, Cafiso, D.S, Kadokura, H, Beckwith, J, Bushweller, J.H. | 登録日 | 2008-08-01 | 公開日 | 2008-10-07 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation. Mol.Cell, 31, 2008
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3RIG
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![BU of 3rig by Molmil](/molmil-images/mine/3rig) | |
2HVJ
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![BU of 2hvj by Molmil](/molmil-images/mine/2hvj) | Crystal structure of KcsA-Fab-TBA complex in low K+ | 分子名称: | (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, NONAN-1-OL, POTASSIUM ION, ... | 著者 | Zhou, Y. | 登録日 | 2006-07-28 | 公開日 | 2007-02-20 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel. J.Mol.Biol., 366, 2007
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2HVK
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![BU of 2hvk by Molmil](/molmil-images/mine/2hvk) | crystal structure of the KcsA-Fab-TBA complex in high K+ | 分子名称: | (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, Antibody Fab heavy chain, Antibody Fab light chain, ... | 著者 | Zhou, Y. | 登録日 | 2006-07-28 | 公開日 | 2007-02-20 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel. J.Mol.Biol., 366, 2007
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3RIY
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![BU of 3riy by Molmil](/molmil-images/mine/3riy) | |
2K73
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![BU of 2k73 by Molmil](/molmil-images/mine/2k73) | Solution NMR structure of integral membrane protein DsbB | 分子名称: | Disulfide bond formation protein B | 著者 | Zhou, Y, Cierpicki, T, Flores Jimenez, R.H, Lukasik, S.M, Ellena, J.F, Cafiso, D.S, Kadokura, H, Beckwith, J, Bushweller, J.H. | 登録日 | 2008-08-01 | 公開日 | 2008-10-07 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation. Mol.Cell, 31, 2008
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3U3D
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![BU of 3u3d by Molmil](/molmil-images/mine/3u3d) | |
3U31
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![BU of 3u31 by Molmil](/molmil-images/mine/3u31) | |
6KIM
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![BU of 6kim by Molmil](/molmil-images/mine/6kim) | |
6IQL
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![BU of 6iql by Molmil](/molmil-images/mine/6iql) | Crystal structure of dopamine receptor D4 bound to the subtype-selective ligand, L745870 | 分子名称: | 3-{[4-(4-chlorophenyl)piperazin-1-yl]methyl}-1H-pyrrolo[2,3-b]pyridine, D(4) dopamine receptor,Soluble cytochrome b562,D(4) dopamine receptor | 著者 | Zhou, Y, Cao, C, Zhang, X.C. | 登録日 | 2018-11-08 | 公開日 | 2019-12-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal structure of dopamine receptor D4 bound to the subtype selective ligand, L745870. Elife, 8, 2019
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1K4C
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![BU of 1k4c by Molmil](/molmil-images/mine/1k4c) | Potassium Channel KcsA-Fab complex in high concentration of K+ | 分子名称: | DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ... | 著者 | Zhou, Y, Morais-Cabral, J.H, Kaufman, A, MacKinnon, R. | 登録日 | 2001-10-07 | 公開日 | 2001-11-14 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution. Nature, 414, 2001
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1K4D
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![BU of 1k4d by Molmil](/molmil-images/mine/1k4d) | Potassium Channel KcsA-Fab complex in low concentration of K+ | 分子名称: | DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ... | 著者 | Zhou, Y, Morais-Cabral, J.H, Kaufman, A, MacKinnon, R. | 登録日 | 2001-10-07 | 公開日 | 2001-11-14 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution. Nature, 414, 2001
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1R3J
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![BU of 1r3j by Molmil](/molmil-images/mine/1r3j) | potassium channel KcsA-Fab complex in high concentration of Tl+ | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ... | 著者 | Zhou, Y, MacKinnon, R. | 登録日 | 2003-10-02 | 公開日 | 2003-11-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates J.Mol.Biol., 333, 2003
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1R3I
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![BU of 1r3i by Molmil](/molmil-images/mine/1r3i) | potassium channel KcsA-Fab complex in Rb+ | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ... | 著者 | Zhou, Y, MacKinnon, R. | 登録日 | 2003-10-02 | 公開日 | 2003-11-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates J.Mol.Biol., 333, 2003
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1R3L
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![BU of 1r3l by Molmil](/molmil-images/mine/1r3l) | potassium channel KcsA-Fab complex in Cs+ | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, CESIUM ION, ... | 著者 | Zhou, Y, MacKinnon, R. | 登録日 | 2003-10-02 | 公開日 | 2003-11-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates J.Mol.Biol., 333, 2003
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1R3K
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![BU of 1r3k by Molmil](/molmil-images/mine/1r3k) | potassium channel KcsA-Fab complex in low concentration of Tl+ | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ... | 著者 | Zhou, Y, MacKinnon, R. | 登録日 | 2003-10-02 | 公開日 | 2003-11-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates J.Mol.Biol., 333, 2003
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6XRZ
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![BU of 6xrz by Molmil](/molmil-images/mine/6xrz) | The 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome | 分子名称: | Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome | 著者 | Zhang, K, Zheludev, I, Hagey, R, Wu, M, Haslecker, R, Hou, Y, Kretsch, R, Pintilie, G, Rangan, R, Kladwang, W, Li, S, Pham, E, Souibgui, C, Baric, R, Sheahan, T, Souza, V, Glenn, J, Chiu, W, Das, R. | 登録日 | 2020-07-14 | 公開日 | 2020-08-19 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | 主引用文献 | Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome. Biorxiv, 2020
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8W07
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![BU of 8w07 by Molmil](/molmil-images/mine/8w07) | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-402 | 分子名称: | (1R,2S,4R)-N-cyclohexyl-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, (1S,2R,4S)-N-cyclohexyl-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.K, Nettles, K.W. | 登録日 | 2024-02-13 | 公開日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VYX
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![BU of 8vyx by Molmil](/molmil-images/mine/8vyx) | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-410 | 分子名称: | 4,4'-[(1S,4S,5R)-5-(3,4-dihydroquinoline-1(2H)-sulfonyl)-7-oxabicyclo[2.2.1]hept-2-ene-2,3-diyl]diphenol, Estrogen receptor | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2024-02-09 | 公開日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proc.Natl.Acad.Sci.USA, 121, 2024
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8W03
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![BU of 8w03 by Molmil](/molmil-images/mine/8w03) | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-1154 | 分子名称: | (1S,2R,4S)-N-(4-chlorophenyl)-5,6-bis(4-hydroxyphenyl)-N-(2,2,2-trifluoroethyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2024-02-13 | 公開日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VZ0
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![BU of 8vz0 by Molmil](/molmil-images/mine/8vz0) | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-400 | 分子名称: | (1S,2R,4S)-N-(cyclopropylmethyl)-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2024-02-09 | 公開日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VZP
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![BU of 8vzp by Molmil](/molmil-images/mine/8vzp) | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-403 | 分子名称: | (1S,2R,4S)-N-(2-hydroxyethyl)-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2024-02-12 | 公開日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VYT
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![BU of 8vyt by Molmil](/molmil-images/mine/8vyt) | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-411 | 分子名称: | 4,4'-[(1R,4R,5S)-5-(2,3-dihydro-1H-indole-1-sulfonyl)-7-oxabicyclo[2.2.1]hept-2-ene-2,3-diyl]diphenol, Estrogen receptor | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2024-02-09 | 公開日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VZ1
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![BU of 8vz1 by Molmil](/molmil-images/mine/8vz1) | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-409 | 分子名称: | 4,4'-[(1S,4S,5R)-5-(6-methoxy-3,4-dihydroquinoline-1(2H)-sulfonyl)-7-oxabicyclo[2.2.1]hept-2-ene-2,3-diyl]diphenol, Estrogen receptor | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2024-02-09 | 公開日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proc.Natl.Acad.Sci.USA, 121, 2024
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