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PDB: 437 件

6LUJ
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Crystal structure of the SAMD1 SAM domain
分子名称: Atherin, SULFATE ION
著者Cao, Y, Zhou, Y, Wang, Z.
登録日2020-01-29
公開日2021-02-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands.
Sci Adv, 7, 2021
3S96
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Crystal structure of 3B5H10
分子名称: 3B5H10 FAB heavy chain, 3B5H10 FAB light chain
著者Weisgraber, K, Peters-Libeu, C, Rutenber, E, Newhouse, Y, Finkbeiner, S.
登録日2011-05-31
公開日2012-02-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure.
J.Mol.Biol., 421, 2012
6LUK
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Crystal structure of the SAMD1 SAM domain in another crystal form
分子名称: Atherin, SULFATE ION
著者Cao, Y, Zhou, Y, Wang, Z.
登録日2020-01-29
公開日2021-02-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.054 Å)
主引用文献The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands.
Sci Adv, 7, 2021
8C9M
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HERV-K Gag immature lattice
分子名称: Gag protein
著者Krebs, A.-S, Liu, H.-F, Zhou, Y, Rey, J.S, Levintov, L, Perilla, J.R, Bartesaghi, A, Zhang, P.
登録日2023-01-23
公開日2023-02-01
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Molecular architecture and conservation of an immature human endogenous retrovirus.
Biorxiv, 2023
1JVM
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KCSA POTASSIUM CHANNEL WITH TBA (TETRABUTYLAMMONIUM) AND RUBIDIUM
分子名称: RUBIDIUM ION, TETRABUTYLAMMONIUM ION, Voltage-gated potassium channel
著者Morais-Cabral, J.H, Zhou, Y, MacKinnon, R.
登録日2001-08-30
公開日2001-12-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Energetic optimization of ion conduction rate by the K+ selectivity filter.
Nature, 414, 2001
3WKZ
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Crystal Structure of the Ostrinia furnacalis Group I Chitinase catalytic domain E148Q mutant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase
著者Chen, L, Liu, T, Zhou, Y, Chen, Q, Shen, X, Yang, Q.
登録日2013-11-05
公開日2014-04-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural characteristics of an insect group I chitinase, an enzyme indispensable to moulting.
Acta Crystallogr.,Sect.D, 70, 2014
3X21
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Crystal structure of Escherichia coli nitroreductase NfsB mutant T41L/N71S/F124W
分子名称: FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase
著者Bai, J, Yang, J, Zhou, Y, Yang, Q.
登録日2014-12-06
公開日2015-05-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.002 Å)
主引用文献Altering the regioselectivity of a nitroreductase in the synthesis of arylhydroxylamines by structure-based engineering.
Chembiochem, 16, 2015
3X22
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Crystal structure of Escherichia coli nitroreductase NfsB mutant N71S/F123A/F124W
分子名称: FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase
著者Bai, J, Yang, J, Zhou, Y, Yang, Q.
登録日2014-12-06
公開日2015-11-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural basis of Escherichia coli nitroreductase NfsB triple mutants engineered for improved activity and regioselectivity toward the prodrug CB1954
PROCESS BIOCHEM, 50, 2015
3W4R
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Crystal structure of an insect chitinase from the Asian corn borer, Ostrinia furnacalis
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase
著者Chen, L, Liu, T, Zhou, Y, Shen, X, Yang, Q.
登録日2013-01-10
公開日2014-02-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural characteristics of an insect group I chitinase, an enzyme indispensable to moulting
Acta Crystallogr.,Sect.D, 70, 2014
3WL0
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Crystal structure of Ostrinia furnacalis Group I chitinase catalytic domain E148A mutant in complex with a(GlcNAc)2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase
著者Chen, L, Liu, T, Zhou, Y, Chen, Q, Shen, X, Yang, Q.
登録日2013-11-05
公開日2014-04-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Structural characteristics of an insect group I chitinase, an enzyme indispensable to moulting.
Acta Crystallogr.,Sect.D, 70, 2014
3WL1
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Crystal structure of Ostrinia furnacalis Group I chitinase catalytic domain in complex with reaction products (GlcNAc)2,3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chen, L, Liu, T, Zhou, Y, Chen, Q, Shen, X, Yang, Q.
登録日2013-11-05
公開日2014-04-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.772 Å)
主引用文献Structural characteristics of an insect group I chitinase, an enzyme indispensable to moulting.
Acta Crystallogr.,Sect.D, 70, 2014
1CXV
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STRUCTURE OF RECOMBINANT MOUSE COLLAGENASE-3 (MMP-13)
分子名称: 2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO-PYRAN-4-YL}-N-HYDROXY-ACETAMIDE, CALCIUM ION, PROTEIN (COLLAGENASE-3), ...
著者Botos, I, Meyer, E, Swanson, S.M, Lemaitre, V, Eeckhout, Y, Meyer, E.F.
登録日1999-08-30
公開日2000-08-30
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of recombinant mouse collagenase-3 (MMP-13).
J.Mol.Biol., 292, 1999
2DGN
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Mouse Muscle Adenylosuccinate Synthetase partially ligated complex with GTP, 2'-deoxy-IMP
分子名称: 9-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-6-(PHOSPHONOOXY)-9H-PURINE, Adenylosuccinate synthetase isozyme 1, GUANOSINE-5'-DIPHOSPHATE, ...
著者Iancu, C.V, Zhou, Y, Borza, T, Fromm, H.J, Honzatko, R.B.
登録日2006-03-15
公開日2006-09-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Cavitation as a mechanism of substrate discrimination by adenylosuccinate synthetases.
Biochemistry, 45, 2006
3VTR
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Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 E328A complexed with TMG-chitotriomycin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-2-(trimethylammonio)-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetylglucosaminidase
著者Liu, T, Zhou, Y, Chen, L, Chen, W, Liu, L, Shen, X, Yang, Q.
登録日2012-06-02
公開日2013-01-16
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into cellulolytic and chitinolytic enzymes revealing crucial residues of insect beta-N-acetyl-D-hexosaminidase
Plos One, 7, 2012
3WZF
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Crystal structure of human cytoplasmic aspartate aminotransferase
分子名称: Aspartate aminotransferase, cytoplasmic
著者Jiang, X, Chang, H, Zhou, Y, Chen, L, Yang, Q.
登録日2014-09-24
公開日2015-10-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.991 Å)
主引用文献Recombinant expression, purification and Preliminary crystallographic studies of human cytoplasmic aspartate aminotransferase
To be Published
2GCQ
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Fully ligated E.Coli Adenylosuccinate Synthetase with GTP, 2'-deoxy-IMP and Hadacidin
分子名称: 9-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-6-(PHOSPHONOOXY)-9H-PURINE, Adenylosuccinate Synthetase, GUANOSINE-5'-DIPHOSPHATE, ...
著者Honzatko, R.B, Zhou, Y.
登録日2006-03-14
公開日2007-04-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cavitation as a mechanism of substrate discrimination by adenylosuccinate synthetases
Biochemistry, 45, 2006
3IS1
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Crystal structure of functional region of UafA from Staphylococcus saprophyticus in C2 form at 2.45 angstrom resolution
分子名称: GLYCEROL, Uro-adherence factor A
著者Tanaka, Y, Matsuoka, E, Shouji, Y, Kuroda, M, Tanaka, I, Yao, M.
登録日2009-08-24
公開日2010-09-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure of the functional region of Uro-adherence factor A from Staphylococcus saprophyticus reveals participation of the B domain in ligand binding
Protein Sci., 20, 2011
3IS0
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Crystal structure of functional region of UafA from Staphylococcus saprophyticus in the presence of cholesterol
分子名称: GLYCEROL, Uro-adherence factor A
著者Tanaka, Y, Shouji, Y, Matsuoka, E, Kuroda, M, Tanaka, I, Yao, M.
登録日2009-08-24
公開日2010-09-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of Functional Region of UafA from Staphylococcus saprophyticus
To be Published
3IRP
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Crystal structure of functional region of UafA from Staphylococcus saprophyticus at 1.50 angstrom resolution
分子名称: GLYCEROL, POTASSIUM ION, Uro-adherence factor A
著者Tanaka, Y, Shouji, Y, Matsuoka, E, Kuroda, M, Tanaka, I, Yao, M.
登録日2009-08-24
公開日2010-09-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the functional region of Uro-adherence factor A from Staphylococcus saprophyticus reveals participation of the B domain in ligand binding
Protein Sci., 20, 2011
3IRZ
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Crystal structure of functional region of UafA from Staphylococcus saprophyticus in P212121 form
分子名称: GLYCEROL, Uro-adherence factor A
著者Tanaka, Y, Shouji, Y, Matsuoka, E, Kuroda, M, Tanaka, I, Yao, M.
登録日2009-08-24
公開日2010-09-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the functional region of Uro-adherence factor A from Staphylococcus saprophyticus reveals participation of the B domain in ligand binding
Protein Sci., 20, 2011
1M8S
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Crystal Structures of Cadmium-binding Acidic Phospholipase A2 from the Venom of Agkistrodon halys pallas at 1.9 Resolution (crystal grown at pH 5.9)
分子名称: 1,4-BUTANEDIOL, CADMIUM ION, phospholipase a2
著者Xu, S, Gu, L, Zhou, Y, Lin, Z.
登録日2002-07-25
公開日2003-02-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of cadmium-binding acidic phospholipase A(2) from the venom of Agkistrodon halys Pallas at 1.9A resolutio
Biochem.Biophys.Res.Commun., 300, 2003
6FCE
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NMR ensemble of Macrocyclic Peptidomimetic Containing Constrained a,a-dialkylated Amino Acids with Potent and Selective Activity at Human Melanocortin Receptors
分子名称: ACP-HIS-DPHE-ARG-TRP-ASP-NH2
著者Brancaccio, D, Carotenuto, A, Grieco, P, Merlino, F, Zhou, Y, Cai, M, Yousif, A.M, Di Maro, S, Novellino, E, Hruby, V.J.
登録日2017-12-20
公開日2018-04-25
最終更新日2024-10-16
実験手法SOLUTION NMR
主引用文献Development of Macrocyclic Peptidomimetics Containing Constrained alpha , alpha-Dialkylated Amino Acids with Potent and Selective Activity at Human Melanocortin Receptors.
J. Med. Chem., 61, 2018
6IW7
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structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease
分子名称: (2S)-2-benzamido-4-methyl-pentanoic acid, 4-[(4-fluoro-2-methyl-3H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline, ATP-dependent Clp protease proteolytic subunit 1, ...
著者Bao, R, Luo, Y.F, Zhu, Y.B, Yang, Y, Zhou, Y.Z.
登録日2018-12-04
公開日2020-01-01
最終更新日2024-10-02
実験手法X-RAY DIFFRACTION (2.692121 Å)
主引用文献structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease
To Be Published
6S47
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Saccharomyces cerevisiae 80S ribosome bound with ABCF protein New1
分子名称: 18S rRNA (1707-MER), 28S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Kasari, V, Pochopien, A.A, Margus, T, Murina, V, Turnbull, K, Zhou, Y, Nissan, T, Graf, M, Novacek, J, Atkinson, G.C, Johansson, M.J.O, Wilson, D.N, Hauryliuk, V.
登録日2019-06-26
公開日2019-07-24
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献A role for the Saccharomyces cerevisiae ABCF protein New1 in translation termination/recycling.
Nucleic Acids Res., 47, 2019
3WMC
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Crystal structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with naphthalimide derivative Q2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(dimethylamino)-2-(2-{[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]amino}ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione, Beta-hexosaminidase
著者Chen, L, Zhou, Y, Chen, L, Yang, Q.
登録日2013-11-16
公開日2014-11-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.095 Å)
主引用文献A crystal structure-guided rational design switching non-carbohydrate inhibitors' specificity between two beta-GlcNAcase homologs
Sci Rep, 4, 2014

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