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PDB: 145 件
6INE
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BU of 6ine by Molmil
Crystal Structure of human ASH1L-MRG15 complex
分子名称: GLYCEROL, Histone-lysine N-methyltransferase ASH1L, Mortality factor 4-like protein 1, ...
著者Hou, P, Huang, C, Liu, C.P, Yu, T, Yin, Y, Zhu, B, Xu, R.M.
登録日2018-10-25
公開日2019-03-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding.
Structure, 27, 2019
8UKU
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BU of 8uku by Molmil
RNA polymerase II elongation complex with Fapy-dG lesion with CMP added
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Hou, P, Oh, J, Wang, D.
登録日2023-10-15
公開日2024-04-24
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG.
J.Am.Chem.Soc., 146, 2024
8UKQ
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BU of 8ukq by Molmil
RNA polymerase II elongation complex with Fapy-dG lesion in apo state
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Hou, P, Oh, J, Wang, D.
登録日2023-10-15
公開日2024-04-24
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG.
J.Am.Chem.Soc., 146, 2024
8UKR
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BU of 8ukr by Molmil
RNA polymerase II elongation complex with Fapy-dG lesion soaking with ATP before chemistry
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
著者Hou, P, Oh, J, Wang, D.
登録日2023-10-15
公開日2024-04-24
実験手法X-RAY DIFFRACTION (3.78 Å)
主引用文献Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG.
J.Am.Chem.Soc., 146, 2024
8UKS
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BU of 8uks by Molmil
RNA polymerase II elongation complex with Fapy-dG lesion soaking with CTP before chemistry
分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
著者Hou, P, Oh, J, Wang, D.
登録日2023-10-15
公開日2024-04-24
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG.
J.Am.Chem.Soc., 146, 2024
8UKT
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BU of 8ukt by Molmil
RNA polymerase II elongation complex with Fapy-dG lesion with AMP added
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Hou, P, Oh, J, Wang, D.
登録日2023-10-15
公開日2024-04-24
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG.
J.Am.Chem.Soc., 146, 2024
7FEX
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BU of 7fex by Molmil
Crystal structure of Sus scrofa Schlafen11 N-terminal domain (2.69 A)
分子名称: SLFN11
著者Hou, P, Hao, W, Cui, S.
登録日2021-07-22
公開日2023-06-07
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Structural and biochemical characterization of Schlafen11 N-terminal domain.
Nucleic Acids Res., 2023
7OX8
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BU of 7ox8 by Molmil
Target-bound SpCas9 complex with TRAC full RNA guide
分子名称: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ...
著者Donohoue, P, Pacesa, M, Lau, E, Vidal, B, Irby, M.J, Nyer, D.B, Rotstein, T, Banh, L, Toh, M.T, Gibson, J, Kohrs, B, Baek, K, Owen, A.L.G, Slorach, E.M, van Overbeek, M, Fuller, C.K, May, A.P, Jinek, M, Cameron, P.
登録日2021-06-22
公開日2021-09-15
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells.
Mol.Cell, 81, 2021
7OXA
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BU of 7oxa by Molmil
Target-bound SpCas9 complex with AAVS1 chimeric RNA-DNA guide
分子名称: AAVS1 non-target DNA strand, AAVS1 target DNA strand, CRISPR-associated endonuclease Cas9/Csn1, ...
著者Donohoue, P, Pacesa, M, Lau, E, Vidal, B, Irby, M.J, Nyer, D.B, Rotstein, T, Banh, L, Toh, M.T, Gibson, J, Kohrs, B, Baek, K, Owen, A.L.G, Slorach, E.M, van Overbeek, M, Fuller, C.K, May, A.P, Jinek, M, Cameron, P.
登録日2021-06-22
公開日2021-09-15
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells.
Mol.Cell, 81, 2021
7OX7
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BU of 7ox7 by Molmil
Target-bound SpCas9 complex with TRAC chimeric RNA-DNA guide
分子名称: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ...
著者Donohoue, P, Pacesa, M, Lau, E, Vidal, B, Irby, M.J, Nyer, D.B, Rotstein, T, Banh, L, Toh, M.T, Gibson, J, Kohrs, B, Baek, K, Owen, A.L.G, Slorach, E.M, van Overbeek, M, Fuller, C.K, May, A.P, Jinek, M, Cameron, P.
登録日2021-06-22
公開日2021-09-15
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells.
Mol.Cell, 81, 2021
5XYJ
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BU of 5xyj by Molmil
Purification,crystallization and structural analysis of cytoplastic acetoacetyl-CoA thiolase from Saccharomyces cerevisiae
分子名称: Acetyl-CoA acetyltransferase, GLYCEROL
著者Zhou, P.F.
登録日2017-07-08
公開日2018-07-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Purification,crystallization and structural analysis of cytoplastic acetoacetyl-CoA thiolase from Saccharomyces cerevisiae
To Be Published
3VM7
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BU of 3vm7 by Molmil
Structure of an Alpha-Amylase from Malbranchea cinnamomea
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-amylase, ...
著者Zhou, P, Hu, S.Q, Zhou, Y, Han, P, Yang, S.Q, Jiang, Z.Q.
登録日2011-12-09
公開日2013-05-29
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献A Novel Multifunctional alpha-Amylase from the Thermophilic Fungus Malbranchea cinnamomea: Biochemical Characterization and Three-Dimensional Structure.
Appl Biochem Biotechnol., 170, 2013
5XZ5
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BU of 5xz5 by Molmil
Purification,crystallization and structural analysis of cytoplastic acetoacetyl-CoA thiolase from Saccharomyces cerevisiae
分子名称: Acetyl-CoA acetyltransferase
著者Zhou, P.F, Zhu, Z.L.
登録日2017-07-11
公開日2018-07-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Purification,crystallization and structural analysis of cytoplastic acetoacetyl-CoA thiolase from Saccharomyces cerevisiae
To Be Published
1IBX
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BU of 1ibx by Molmil
NMR STRUCTURE OF DFF40 AND DFF45 N-TERMINAL DOMAIN COMPLEX
分子名称: CHIMERA OF IGG BINDING PROTEIN G AND DNA FRAGMENTATION FACTOR 45, DNA FRAGMENTATION FACTOR 40
著者Zhou, P, Lugovskoy, A.A, McCarty, J.S, Li, P, Wagner, G.
登録日2001-03-29
公開日2001-05-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of DFF40 and DFF45 N-terminal domain complex and mutual chaperone activity of DFF40 and DFF45.
Proc.Natl.Acad.Sci.USA, 98, 2001
1C15
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BU of 1c15 by Molmil
SOLUTION STRUCTURE OF APAF-1 CARD
分子名称: APOPTOTIC PROTEASE ACTIVATING FACTOR 1
著者Zhou, P, Chou, J, Olea, R.S, Yuan, J, Wagner, G.
登録日1999-07-20
公開日1999-09-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: a structural basis for specific adaptor/caspase interaction.
Proc.Natl.Acad.Sci.USA, 96, 1999
2I5O
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BU of 2i5o by Molmil
Solution Structure of the Ubiquitin-Binding Zinc Finger (UBZ) Domain of the Human DNA Y-Polymerase Eta
分子名称: DNA polymerase eta, ZINC ION
著者Zhou, P, Bomar, M.G.
登録日2006-08-25
公開日2007-03-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the ubiquitin-binding zinc finger domain of human DNA Y-polymerase eta.
Embo Rep., 8, 2007
1A66
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BU of 1a66 by Molmil
SOLUTION NMR STRUCTURE OF THE CORE NFATC1/DNA COMPLEX, 18 STRUCTURES
分子名称: CORE NFATC1, DNA (5'-D(*CP*AP*AP*TP*TP*TP*TP*CP*CP*TP*CP*G)-3'), DNA (5'-D(*CP*GP*AP*GP*GP*AP*AP*AP*AP*TP*TP*G)-3')
著者Zhou, P, Sun, L.J, Doetsch, V, Wagner, G, Verdine, G.L.
登録日1998-03-06
公開日1998-06-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the core NFATC1/DNA complex.
Cell(Cambridge,Mass.), 92, 1998
4REE
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BU of 4ree by Molmil
Crystal Structure of TR3 LBD in complex with Molecule 6
分子名称: 1-(2,3,4-trihydroxyphenyl)nonan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1
著者Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Wang, W.J, Yuan, W, Hou, P.P, Wu, Q, Lin, T.W.
登録日2014-09-22
公開日2015-09-09
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity
Chem.Biol., 22, 2015
4REF
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BU of 4ref by Molmil
Crystal Structure of TR3 LBD_L449W in complex with Molecule 2
分子名称: 1-(3,4,5-trihydroxyphenyl)hexan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1
著者Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Wang, W.J, Yuan, W, Hou, P.P, Wu, Q, Lin, T.W.
登録日2014-09-22
公開日2015-09-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity
Chem.Biol., 22, 2015
4WHG
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BU of 4whg by Molmil
Crystal Structure of TR3 LBD in complex with Molecule 3
分子名称: 1-(3,4,5-trihydroxyphenyl)octan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1
著者Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Wang, W.J, Wang, Y, Hou, P.P, Wu, Q, Lin, T.W.
登録日2014-09-22
公開日2015-09-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity
Chem.Biol., 22, 2015
4WHF
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BU of 4whf by Molmil
Crystal Structure of TR3 LBD in complex with 1-(3,4,5-trihydroxyphenyl)decan-1-one
分子名称: 1-(3,4,5-trihydroxyphenyl)decan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1
著者Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Wang, W.J, Wang, Y, Hou, P.P, Wu, Q, Lin, T.W.
登録日2014-09-22
公開日2015-09-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity
Chem.Biol., 22, 2015
4RE8
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BU of 4re8 by Molmil
Crystal Structure of TR3 LBD in complex with Molecule 5
分子名称: 1-(3,4,5-trihydroxyphenyl)dodecan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1
著者Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Weijia, W, Yuan, W, Hou, P.P, Wu, Q, Lin, T.W.
登録日2014-09-22
公開日2015-09-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity
Chem.Biol., 22, 2015
7WYL
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BU of 7wyl by Molmil
Structure of the EV71 3Cpro with 337 inhibitor
分子名称: 3C protein, N-methyl-N-[[4-(trifluoromethyl)-1,3-thiazol-2-yl]methyl]prop-2-enamide
著者Qin, B, Hou, P, Gao, X, Cui, S.
登録日2022-02-16
公開日2022-06-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Acrylamide fragment inhibitors that induce unprecedented conformational distortions in enterovirus 71 3C and SARS-CoV-2 main protease.
Acta Pharm Sin B, 12, 2022
7WYO
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BU of 7wyo by Molmil
Structure of the EV71 3Cpro with 338 inhibitor
分子名称: 3C protein, N-methyl-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-ylmethyl)prop-2-enamide
著者Qin, B, Hou, P, Gao, X, Cui, S.
登録日2022-02-16
公開日2022-06-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.402 Å)
主引用文献Acrylamide fragment inhibitors that induce unprecedented conformational distortions in enterovirus 71 3C and SARS-CoV-2 main protease.
Acta Pharm Sin B, 12, 2022
7WYP
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BU of 7wyp by Molmil
Structure of the SARS-COV-2 main protease with EN102 inhibitor
分子名称: 3C-like proteinase, N-(1,3-benzothiazol-2-ylmethyl)-N-cyclopropyl-prop-2-enamide
著者Qin, B, Hou, P, Gao, X, Cui, S.
登録日2022-02-16
公開日2022-06-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Acrylamide fragment inhibitors that induce unprecedented conformational distortions in enterovirus 71 3C and SARS-CoV-2 main protease.
Acta Pharm Sin B, 12, 2022

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