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PDB: 230 results

6VG8
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BU of 6vg8 by Molmil
Crystal structure of the DNA binding domains of human FLI1 and Runx2 in complex with 16-mer DNA CAGAGGATGTGGCTTC
Descriptor: DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), Friend leukemia integration 1 transcription factor, ...
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2020-01-07
Release date:2020-11-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.31 Å)
Cite:Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins.
Structure, 29, 2021
5W35
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BU of 5w35 by Molmil
Crystal structure of the RNA polymerase domain (RPD) of Mycobacterium tuberculosis primase DnaG in complex with a double-stranded DNA oligomer with a 1-nucleotide overhang
Descriptor: DNA primase, synthetic DNA oligomer 5'-CCACTTCCGGTC, synthetic DNA oligomer 5'-TGACCGGAAGTGG
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2017-06-07
Release date:2018-03-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Structures of the Catalytic Domain of Bacterial Primase DnaG in Complexes with DNA Provide Insight into Key Priming Events.
Biochemistry, 57, 2018
5W33
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BU of 5w33 by Molmil
Crystal structure of the RNA polymerase domain (RPD) of Mycobacterium tuberculosis primase DnaG
Descriptor: DNA primase, SULFATE ION
Authors:Hou, C, Biswas, T, Tsodikov, O.V.
Deposit date:2017-06-07
Release date:2018-03-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structures of the Catalytic Domain of Bacterial Primase DnaG in Complexes with DNA Provide Insight into Key Priming Events.
Biochemistry, 57, 2018
5W36
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BU of 5w36 by Molmil
Crystal structure of the RNA polymerase domain (RPD) of Mycobacterium tuberculosis primase DnaG in complex with a double-stranded DNA oligomer with a 6-nucleotide overhang
Descriptor: DNA primase, STRONTIUM ION, synthetic DNA 5'-TATCGTCCCGCCTC
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2017-06-07
Release date:2018-03-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structures of the Catalytic Domain of Bacterial Primase DnaG in Complexes with DNA Provide Insight into Key Priming Events.
Biochemistry, 57, 2018
5EAY
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BU of 5eay by Molmil
Crystal structure of a Dna2 peptide in complex with Rpa 70N
Descriptor: DNA replication ATP-dependent helicase/nuclease DNA2, Replication protein A 70 kDa DNA-binding subunit
Authors:Zhou, C, Pourmal, S, Pavletich, N.P.
Deposit date:2015-10-17
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Dna2 nuclease-helicase structure, mechanism and regulation by Rpa.
Elife, 4, 2015
5EAN
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BU of 5ean by Molmil
Crystal structure of Dna2 in complex with a 5' overhang DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*AP*CP*TP*CP*TP*GP*CP*CP*AP*AP*GP*AP*GP*GP*A)-3'), ...
Authors:Zhou, C, Pourmal, S, Pavletich, N.P.
Deposit date:2015-10-16
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Dna2 nuclease-helicase structure, mechanism and regulation by Rpa.
Elife, 4, 2015
5EAX
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BU of 5eax by Molmil
Crystal structure of Dna2 in complex with an ssDNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA replication ATP-dependent helicase/nuclease DNA2, ...
Authors:Zhou, C, Pourmal, S, Pavletich, N.P.
Deposit date:2015-10-17
Release date:2015-11-18
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Dna2 nuclease-helicase structure, mechanism and regulation by Rpa.
Elife, 4, 2015
5EAW
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BU of 5eaw by Molmil
Crystal structure of Dna2 nuclease-helicase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA replication ATP-dependent helicase/nuclease DNA2, IRON/SULFUR CLUSTER
Authors:Zhou, C, Pourmal, S, Pavletich, N.P.
Deposit date:2015-10-17
Release date:2015-11-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Dna2 nuclease-helicase structure, mechanism and regulation by Rpa.
Elife, 4, 2015
6S3W
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BU of 6s3w by Molmil
Solution NMR Structure of TolAIII Bound to a Peptide Derived from the N-terminus of TolB
Descriptor: Cell envelope integrity/translocation protein TolA, TolBp
Authors:Kleanthous, C, Redfield, C, Rajasekar, K, Holmes, P.
Deposit date:2019-06-26
Release date:2020-03-25
Last modified:2024-07-03
Method:SOLUTION NMR
Cite:The lipoprotein Pal stabilises the bacterial outer membrane during constriction by a mobilisation-and-capture mechanism.
Nat Commun, 11, 2020
7CH7
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BU of 7ch7 by Molmil
Cryo-EM structure of E.coli MlaFEB
Descriptor: Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, Phospholipid ABC transporter ATP-binding protein MlaF
Authors:Zhou, C, Shi, H, Huang, Y.
Deposit date:2020-07-05
Release date:2021-05-19
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa.
J.Mol.Biol., 433, 2021
7CHA
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BU of 7cha by Molmil
Cryo-EM structure of P.aeruginosa MlaFEBD with AMPPNP
Descriptor: 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, MlaD domain-containing protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Zhou, C, Shi, H, Zhang, M, Huang, Y.
Deposit date:2020-07-05
Release date:2021-05-19
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa.
J.Mol.Biol., 433, 2021
7CH6
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BU of 7ch6 by Molmil
Cryo-EM structure of E.coli MlaFEB with AMPPNP
Descriptor: Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Zhou, C, Shi, H, Zhang, M, Huang, Y.
Deposit date:2020-07-05
Release date:2021-08-04
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa.
J.Mol.Biol., 433, 2021
7CH8
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BU of 7ch8 by Molmil
Cryo-EM structure of P.aeruginosa MlaFEBD with ADP-V
Descriptor: 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, ADP METAVANADATE, MAGNESIUM ION, ...
Authors:Zhou, C, Shi, H, Zhang, M, Huang, Y.
Deposit date:2020-07-05
Release date:2021-10-06
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa.
J.Mol.Biol., 433, 2021
7CH9
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BU of 7ch9 by Molmil
Cryo-EM structure of P.aeruginosa MlaFEBD
Descriptor: 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, MlaD domain-containing protein, Probable ATP-binding component of ABC transporter, ...
Authors:Zhou, C, Shi, H, Zhang, M, Huang, Y.
Deposit date:2020-07-05
Release date:2021-10-06
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa.
J.Mol.Biol., 433, 2021
8J2P
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BU of 8j2p by Molmil
Crystal structure of PML B-box2
Descriptor: Maltose/maltodextrin-binding periplasmic protein,Protein PML, ZINC ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Zhou, C, Zang, N, Zhang, J.
Deposit date:2023-04-15
Release date:2023-09-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural Basis of PML-RARA Oncoprotein Targeting by Arsenic Unravels a Cysteine Rheostat Controlling PML Body Assembly and Function.
Cancer Discov, 13, 2023
8J25
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BU of 8j25 by Molmil
Crystal structure of PML B-box2 mutant
Descriptor: Maltose/maltodextrin-binding periplasmic protein,Protein PML, ZINC ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Zhou, C, Zang, N, Zhang, J.
Deposit date:2023-04-14
Release date:2023-09-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis of PML-RARA Oncoprotein Targeting by Arsenic Unravels a Cysteine Rheostat Controlling PML Body Assembly and Function.
Cancer Discov, 13, 2023
2LGW
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BU of 2lgw by Molmil
Solution Structure of the J Domain of HSJ1a
Descriptor: DnaJ homolog subfamily B member 2
Authors:Zhou, C, Gao, X, Cao, C, Hu, H.
Deposit date:2011-08-02
Release date:2012-01-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The C-terminal helices of heat shock protein 70 are essential for J-domain binding and ATPase activation.
J.Biol.Chem., 287, 2012
2KLZ
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BU of 2klz by Molmil
Solution Structure of the Tandem UIM Domain of Ataxin-3 Complexed with Ubiquitin
Descriptor: Ataxin-3
Authors:Zhou, C, Song, A, Lin, D, Hu, H.
Deposit date:2009-07-12
Release date:2010-07-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution Structure of the Tandem UIM Domain of Ataxin-3 Complexed with Ubiquitin
To be Published
2JNH
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BU of 2jnh by Molmil
Solution Structure of the UBA Domain from Cbl-b
Descriptor: E3 ubiquitin-protein ligase CBL-B
Authors:Zhou, C, Zhou, Z, Lin, D, Hu, H.
Deposit date:2007-01-24
Release date:2008-02-05
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Differential ubiquitin binding of the UBA domains from human c-Cbl and Cbl-b: NMR structural and biochemical insights
Protein Sci., 17, 2008
2JWQ
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BU of 2jwq by Molmil
G-quadruplex recognition by quinacridines: a SAR, NMR and Biological study
Descriptor: DNA (5'-D(*DTP*DTP*DAP*DGP*DGP*DGP*DT)-3'), N,N'-(dibenzo[b,j][1,7]phenanthroline-2,10-diyldimethanediyl)dipropan-1-amine
Authors:Hounsou, C, Guittat, L, Monchaud, D, Jourdan, M, Saettel, N, Mergny, J.L, Teulade-Fichou, M.
Deposit date:2007-10-23
Release date:2008-03-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:G-Quadruplex Recognition by Quinacridines: a SAR, NMR, and Biological Study
ChemMedChem, 2, 2007
2LMG
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BU of 2lmg by Molmil
Solution Structure of The C-terminal Domain (537-610) of Human Heat Shock Protein 70
Descriptor: Heat shock 70 kDa protein 1A/1B
Authors:Zhou, C, Gao, X, Wu, M, Hu, H.
Deposit date:2011-12-01
Release date:2012-01-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The C-terminal helices of heat shock protein 70 are essential for J-domain binding and ATPase activation.
J.Biol.Chem., 287, 2012
7XT2
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BU of 7xt2 by Molmil
Crystal structure of TRIM72
Descriptor: Tripartite motif-containing protein 72, ZINC ION
Authors:Zhou, C, Ma, Y.M, Ding, L.
Deposit date:2022-05-15
Release date:2023-03-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for TRIM72 oligomerization during membrane damage repair.
Nat Commun, 14, 2023
7XKS
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BU of 7xks by Molmil
Crystal structure of an alkaline pectate lyase from Bacillus clausii
Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, Pectate lyase
Authors:Zhou, C, Zheng, Y.Y, Liu, W.D, Ma, Y.
Deposit date:2022-04-20
Release date:2023-03-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure of an Alkaline Pectate Lyase and Rational Engineering with Improved Thermo-Alkaline Stability for Efficient Ramie Degumming.
Int J Mol Sci, 24, 2022
7SG7
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BU of 7sg7 by Molmil
In situ cryo-EM structure of bacteriophage Sf6 gp8:gp14N complex at 2.8 A resolution
Descriptor: Gene 14 protein, Gene 8 protein
Authors:Li, F, Cingolani, G, Hou, C.
Deposit date:2021-10-05
Release date:2022-11-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:High-resolution cryo-EM structure of the Shigella virus Sf6 genome delivery tail machine.
Sci Adv, 8, 2022
5EBV
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BU of 5ebv by Molmil
Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor 11c and CoA
Descriptor: 5-(4-chlorophenyl)-~{N}-[3-(3,4-dihydro-1~{H}-isoquinolin-2-yl)propyl]-4-methyl-1,1-bis(oxidanylidene)-1,2-thiazol-3-amine, CHLORIDE ION, COENZYME A, ...
Authors:Gajadeera, C.S, Hou, C, Garneau-Tsodikova, S, Tsodikov, O.V.
Deposit date:2015-10-19
Release date:2016-03-30
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Potent Inhibitors of Acetyltransferase Eis Overcome Kanamycin Resistance in Mycobacterium tuberculosis.
Acs Chem.Biol., 11, 2016

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数据于2024-11-13公开中

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