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PDB: 227 件
7NG8
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Trimeric efflux pump Klebsiella TolC in complex with KlebC
分子名称: Klebicin C activity, Outer membrane channel protein
著者Webby, M.N, Housden, N.G, Kleanthous, C.
登録日2021-02-08
公開日2021-06-30
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Toxin import through the antibiotic efflux channel TolC.
Nat Commun, 12, 2021
7NNA
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Toxin Import Through the Antibiotic Efflux Channel TolC
分子名称: Klebicin C activity
著者Lowe, E.D, Kleanthous, C, Housden, N.G.
登録日2021-02-24
公開日2021-07-07
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Toxin import through the antibiotic efflux channel TolC.
Nat Commun, 12, 2021
4XS3
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Crystal structure of a metabolic reductase with (E)-1-benzyl-5-((1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)pyridin-2(1H)-one
分子名称: (E)-1-benzyl-5-((1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)pyridin-2(1H)-one, Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zheng, B, Wu, F, Jiang, H, Kogiso, M, Yao, Y, Zhou, C, Li, X, Song, Y.
登録日2015-01-21
公開日2016-07-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.291 Å)
主引用文献Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds.
J.Med.Chem., 58, 2015
4XRX
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Crystal structure of a metabolic reductase with (E)-5-((1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)pyridin-2(1H)-one
分子名称: 5-[(E)-(1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl]pyridin-2(1H)-one, Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zheng, B, Wu, F, Jiang, H, Kogiso, M, Yao, Y, Zhou, C, Li, X, Song, Y.
登録日2015-01-21
公開日2015-12-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds.
J.Med.Chem., 58, 2015
8JZV
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RPA70N-ETAA1 fusion
分子名称: Ewing's tumor-associated antigen 1, Replication protein A 70 kDa DNA-binding subunit
著者Fu, W.M, Wu, Y.Y, Zhou, C.
登録日2023-07-06
公開日2023-09-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
8JZY
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RPA70N-RAD9 fusion
分子名称: Cell cycle checkpoint control protein RAD9A, Replication protein A 70 kDa DNA-binding subunit
著者Fu, W.M, Wu, Y.Y, Zhou, C.
登録日2023-07-06
公開日2023-09-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
8K00
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RPA70N-MRE11 fusion
分子名称: Double-strand break repair protein MRE11, Replication protein A 70 kDa DNA-binding subunit
著者Fu, W.M, Wu, Y.Y, Zhou, C.
登録日2023-07-07
公開日2023-09-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
6THK
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BU of 6thk by Molmil
Structural mechanism of pyocin S5 import into Pseudomonas aeruginosa
分子名称: GLYCEROL, Pyocin S5, ZINC ION
著者Behrens, H.M, Kleanthous, C, Lowe, E.D.
登録日2019-11-20
公開日2020-03-04
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Pyocin S5 Import into Pseudomonas aeruginosa Reveals a Generic Mode of Bacteriocin Transport.
Mbio, 11, 2020
7XV4
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BU of 7xv4 by Molmil
Crystal structure of RPA70N-ATRIP fusion
分子名称: ATR-interacting protein, Replication protein A 70 kDa DNA-binding subunit
著者Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C.
登録日2022-05-20
公開日2023-06-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
7XV1
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Crystal structure of RPA70N-HelB fusion
分子名称: DNA helicase B, Replication protein A 70 kDa DNA-binding subunit
著者Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C.
登録日2022-05-20
公開日2023-06-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
7XUT
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Crystal structure of RPA70N-WRN fusion
分子名称: fusion protein of Replication protein A 70 kDa DNA-binding subunit and Werner syndrome ATP-dependent helicase
著者Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C.
登録日2022-05-19
公開日2023-06-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
7XV0
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Crystal structure of RPA70N-BLMp1 fusion
分子名称: Bloom syndrome protein, Replication protein A 70 kDa DNA-binding subunit
著者Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C.
登録日2022-05-20
公開日2023-06-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
7XUV
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Crystal structure of RPA70N-RMI1 fusion
分子名称: RecQ-mediated genome instability protein 1, Replication protein A 70 kDa DNA-binding subunit
著者Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C.
登録日2022-05-20
公開日2023-06-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
7XUW
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BU of 7xuw by Molmil
Crystal structure of RPA70N-BLMp2 fusion
分子名称: fusion protein of Replication protein A 70 kDa DNA-binding subunit and Bloom syndrome protein
著者Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C.
登録日2022-05-20
公開日2023-06-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
7NST
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BU of 7nst by Molmil
ColicinE9 partial translocation complex
分子名称: Colicin-E9, Outer membrane protein F, Tol-Pal system protein TolB
著者Webby, M.N, Kleanthous, C, Lukoyanova, N, Housden, N.G.
登録日2021-03-08
公開日2021-08-11
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Porin threading drives receptor disengagement and establishes active colicin transport through Escherichia coli OmpF.
Embo J., 40, 2021
7NSU
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ColicinE9 intact translocation complex
分子名称: Colicin-E9, Outer membrane protein F, Tol-Pal system protein TolB, ...
著者Webby, M.N, Kleanthous, C, Lukoyanova, N, Housden, N.G.
登録日2021-03-08
公開日2021-08-11
最終更新日2021-11-17
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Porin threading drives receptor disengagement and establishes active colicin transport through Escherichia coli OmpF.
Embo J., 40, 2021
7W0V
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BU of 7w0v by Molmil
C4'-SCF3-DT modifeid DNA-DNA duplex
分子名称: DNA (5'-D(*CP*CP*AP*TP*(DSW)P*AP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*TP*GP*G)-3')
著者Li, Q, Trajkovski, M, Fan, C, Chen, J, Zhou, Y, Lu, K, Li, H, Su, X, Xi, Z, Plavec, J, Zhou, C.
登録日2021-11-18
公開日2022-11-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献4'-SCF 3 -Labeling Constitutes a Sensitive 19 F NMR Probe for Characterization of Interactions in the Minor Groove of DNA.
Angew.Chem.Int.Ed.Engl., 61, 2022
3JWJ
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BU of 3jwj by Molmil
Crystal structure analysis of the methyltransferase domain of bacterial-AvHen1-CN
分子名称: Hen1
著者Huang, R.H, Chan, C.M, Zhou, C, Brunzelle, J.S.
登録日2009-09-18
公開日2009-10-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and biochemical insights into 2'-O-methylation at the 3'-terminal nucleotide of RNA by Hen1.
Proc.Natl.Acad.Sci.USA, 106, 2009
3JWG
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Crystal structure analysis of the methyltransferase domain of bacterial-CtHen1-C
分子名称: MAGNESIUM ION, Methyltransferase type 12
著者Huang, R.H, Chan, C.M, Zhou, C, Brunzelle, J.S.
登録日2009-09-18
公開日2009-10-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and biochemical insights into 2'-O-methylation at the 3'-terminal nucleotide of RNA by Hen1.
Proc.Natl.Acad.Sci.USA, 106, 2009
3JWI
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Crystal structure analysis of the methyltransferase domain of bacterial-CtHen1-CN
分子名称: Methyltransferase type 12
著者Huang, R.H, Chan, C.M, Zhou, C, Brunzelle, J.S.
登録日2009-09-18
公開日2009-10-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and biochemical insights into 2'-O-methylation at the 3'-terminal nucleotide of RNA by Hen1.
Proc.Natl.Acad.Sci.USA, 106, 2009
3JWH
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BU of 3jwh by Molmil
Crystal structure analysis of the methyltransferase domain of bacterial-AvHen1-C
分子名称: Hen1, S-ADENOSYL-L-HOMOCYSTEINE
著者Huang, R.H, Chan, C.M, Zhou, C, Brunzelle, J.S.
登録日2009-09-18
公開日2009-10-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and biochemical insights into 2'-O-methylation at the 3'-terminal nucleotide of RNA by Hen1.
Proc.Natl.Acad.Sci.USA, 106, 2009
4IXL
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Crystal structure of endo-beta-1,4-xylanase from the alkaliphilic Bacillus sp. SN5
分子名称: SULFATE ION, xylanase
著者Bai, W.Q, Xue, Y.F, Huang, J.X, Zhou, C, Guo, R.T, Ma, Y.H.
登録日2013-01-26
公開日2014-02-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Structure Analysis of Alkaline xylanase from Alkaliphilic Bacillus sp. SN5 Implications for pH-dependent enzyme activity
To be Published
8ODT
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BU of 8odt by Molmil
Structure of TolQR complex from E.coli
分子名称: Tol-Pal system protein TolQ, Tol-Pal system protein TolR
著者Webby, M.N, Kleanthous, C, Press, C.E.
登録日2023-03-09
公開日2023-11-01
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Tunable force transduction through the Escherichia coli cell envelope.
Proc.Natl.Acad.Sci.USA, 120, 2023
8HSY
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BU of 8hsy by Molmil
Acyl-ACP Synthetase structure
分子名称: Acyl-acyl carrier protein synthetase
著者Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y.
登録日2022-12-20
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (2.53 Å)
主引用文献Acyl-ACP Synthetase structure
To Be Published
4L6R
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Structure of the class B human glucagon G protein coupled receptor
分子名称: DI(HYDROXYETHYL)ETHER, Soluble cytochrome b562 and Glucagon receptor chimera
著者Siu, F.Y, He, M, de Graaf, C, Han, G.W, Yang, D, Zhang, Z, Zhou, C, Xu, Q, Wacker, D, Joseph, J.S, Liu, W, Lau, J, Cherezov, V, Katritch, V, Wang, M.W, Stevens, R.C, GPCR Network (GPCR)
登録日2013-06-12
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of the human glucagon class B G-protein-coupled receptor.
Nature, 499, 2013

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