1TX3
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![BU of 1tx3 by Molmil](/molmil-images/mine/1tx3) | HINCII BOUND TO COGNATE DNA | 分子名称: | 5'-D(*GP*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*G)-3', SODIUM ION, Type II restriction enzyme HindII | 著者 | Horton, N.C, Dorner, L.F, Perona, J.J. | 登録日 | 2004-07-01 | 公開日 | 2005-02-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Ca2+ binding in the active site of HincII: implications for the catalytic mechanism Biochemistry, 43, 2004
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1KC6
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![BU of 1kc6 by Molmil](/molmil-images/mine/1kc6) | HincII Bound to Cognate DNA | 分子名称: | 5'-D(P*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*G)-3', SODIUM ION, TYPE II RESTRICTION ENZYME HINCII | 著者 | Horton, N.C, Dorner, L.F, Perona, J.J. | 登録日 | 2001-11-07 | 公開日 | 2001-12-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Sequence selectivity and degeneracy of a restriction endonuclease mediated by DNA intercalation. Nat.Struct.Biol., 9, 2002
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2GIH
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![BU of 2gih by Molmil](/molmil-images/mine/2gih) | Q138F HincII bound to cognate DNA GTCGAC and Ca2+ | 分子名称: | 5'-D(*GP*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*GP*C)-3', CALCIUM ION, Type II restriction enzyme HincII | 著者 | Horton, N.C, Joshi, H.K, Etzkorn, C, Chatwell, L, Bitinaite, J. | 登録日 | 2006-03-28 | 公開日 | 2006-07-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism. J.Biol.Chem., 281, 2006
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2GIJ
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![BU of 2gij by Molmil](/molmil-images/mine/2gij) | Q138F HincII bound to cognate DNA GTTAAC and Ca2+ | 分子名称: | 5'-D(*GP*CP*CP*GP*GP*TP*TP*AP*AP*CP*CP*GP*GP*C)-3', CALCIUM ION, SODIUM ION, ... | 著者 | Horton, N.C, Joshi, H.K. | 登録日 | 2006-03-28 | 公開日 | 2006-07-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism. J.Biol.Chem., 281, 2006
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2GIG
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![BU of 2gig by Molmil](/molmil-images/mine/2gig) | Alteration of sequence specificity of the type II restriction endonuclease HINCII through an indirect readout mechanism | 分子名称: | 5'-D(*GP*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*GP*C)-3', SODIUM ION, Type II restriction enzyme HincII | 著者 | Horton, N.C, Joshi, H.K, Etzkorn, C, Chatwell, L, Bitinaite, J. | 登録日 | 2006-03-28 | 公開日 | 2006-07-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism. J.Biol.Chem., 281, 2006
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2GII
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![BU of 2gii by Molmil](/molmil-images/mine/2gii) | Q138F HincII bound to cognate DNA GTTAAC | 分子名称: | 5'-D(*GP*CP*CP*GP*GP*TP*TP*AP*AP*CP*CP*GP*GP*C)-3', Type II restriction enzyme HincII | 著者 | Horton, N.C, Joshi, H.K. | 登録日 | 2006-03-28 | 公開日 | 2006-07-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism. J.Biol.Chem., 281, 2006
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2GIE
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![BU of 2gie by Molmil](/molmil-images/mine/2gie) | HincII bound to cognate DNA GTTAAC | 分子名称: | 5'-D(*GP*CP*CP*GP*GP*TP*TP*AP*AP*CP*CP*GP*G)-3', SODIUM ION, Type II restriction enzyme HincII | 著者 | Horton, N.C, Joshi, H.K, Etzkorn, C, Chatwell, L, Bitinaite, J. | 登録日 | 2006-03-28 | 公開日 | 2006-07-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism. J.Biol.Chem., 281, 2006
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3N78
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![BU of 3n78 by Molmil](/molmil-images/mine/3n78) | SgrAI bound to Secondary Site DNA and Mg(II) | 分子名称: | DNA (5'-D(*AP*GP*TP*CP*CP*AP*CP*CP*GP*GP*GP*GP*GP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*CP*CP*CP*CP*CP*GP*GP*TP*GP*GP*AP*CP*T)-3'), MAGNESIUM ION, ... | 著者 | Horton, N.C, Little, E.J, Dunten, P.W. | 登録日 | 2010-05-26 | 公開日 | 2010-11-24 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | New clues in the allosteric activation of DNA cleavage by SgrAI: structures of SgrAI bound to cleaved primary-site DNA and uncleaved secondary-site DNA. Acta Crystallogr.,Sect.D, 67, 2011
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3N7B
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![BU of 3n7b by Molmil](/molmil-images/mine/3n7b) | SgrAI bound to secondary site DNA and Ca(II) | 分子名称: | CALCIUM ION, DNA (5'-D(*AP*GP*TP*CP*CP*AP*CP*CP*GP*GP*GP*GP*GP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*CP*CP*CP*CP*CP*GP*GP*TP*GP*GP*AP*CP*T)-3'), ... | 著者 | Horton, N.C, Little, E.J, Dunten, P.W. | 登録日 | 2010-05-26 | 公開日 | 2010-11-24 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | New clues in the allosteric activation of DNA cleavage by SgrAI: structures of SgrAI bound to cleaved primary-site DNA and uncleaved secondary-site DNA. Acta Crystallogr.,Sect.D, 67, 2011
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2AUD
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![BU of 2aud by Molmil](/molmil-images/mine/2aud) | Unliganded HincII | 分子名称: | Type II restriction enzyme HincII | 著者 | Horton, N.C, Little, E.J. | 登録日 | 2005-08-27 | 公開日 | 2005-10-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | DNA-induced conformational changes in Type II restriction endonucleases: The structure of unliganded HincII J.Mol.Biol., 351, 2005
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1STX
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![BU of 1stx by Molmil](/molmil-images/mine/1stx) | |
1RV5
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![BU of 1rv5 by Molmil](/molmil-images/mine/1rv5) | COMPLEX OF ECORV ENDONUCLEASE WITH D(AAAGAT)/D(ATCTT) | 分子名称: | 5'-D(*AP*AP*AP*GP*AP*T*AP*TP*CP*TP*T)-3', ECORV ENDONUCLEASE | 著者 | Horton, N.C, Perona, J.J. | 登録日 | 1998-06-01 | 公開日 | 1998-11-11 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Role of protein-induced bending in the specificity of DNA recognition: crystal structure of EcoRV endonuclease complexed with d(AAAGAT) + d(ATCTT). J.Mol.Biol., 277, 1998
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1SX8
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![BU of 1sx8 by Molmil](/molmil-images/mine/1sx8) | EcoRV bound to cognate DNA and Mn2+ | 分子名称: | 5'-D(*C*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3', MANGANESE (II) ION, Type II restriction enzyme EcoRV | 著者 | Horton, N.C, Perona, J.J. | 登録日 | 2004-03-30 | 公開日 | 2004-04-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | DNA Cleavage by EcoRV Endonuclease: Two Metal Ions in Three Metal Ion Binding Sites Biochemistry, 43, 2004
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1SUZ
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![BU of 1suz by Molmil](/molmil-images/mine/1suz) | |
1SX5
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![BU of 1sx5 by Molmil](/molmil-images/mine/1sx5) | |
2I13
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![BU of 2i13 by Molmil](/molmil-images/mine/2i13) | Aart, a six finger zinc finger designed to recognize ANN triplets | 分子名称: | 5'-D(*CP*AP*GP*AP*TP*GP*TP*AP*GP*GP*GP*AP*AP*AP*AP*GP*CP*CP*CP*GP*GP*G)-3', 5'-D(*GP*CP*CP*CP*GP*GP*GP*CP*TP*TP*TP*TP*CP*CP*CP*TP*AP*CP*AP*TP*CP*T)-3', Aart, ... | 著者 | Horton, N.C, Segal, D.J, Bhakta, M, Crotty, J.W, Barbas III, C.F. | 登録日 | 2006-08-12 | 公開日 | 2006-10-03 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structure of Aart, a Designed Six-finger Zinc Finger Peptide, Bound to DNA. J.Mol.Biol., 363, 2006
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3E44
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![BU of 3e44 by Molmil](/molmil-images/mine/3e44) | Q138F HincII bound to cleaved DNA (GTT | AAC) and Mn2+ | 分子名称: | 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DT)-3', 5'-D(P*DAP*DAP*DCP*DCP*DGP*DGP*DC)-3', MANGANESE (II) ION, ... | 著者 | Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M. | 登録日 | 2008-08-08 | 公開日 | 2008-08-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | DNA distortion and specificity in a sequence-specific endonuclease. J.Mol.Biol., 383, 2008
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3E41
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![BU of 3e41 by Molmil](/molmil-images/mine/3e41) | Q138F HincII bound to GTCGAC and 5 mM Ca2+ | 分子名称: | 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DCP*DGP*DAP*DCP*DCP*DGP*DGP*DC)-3', CALCIUM ION, SODIUM ION, ... | 著者 | Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M. | 登録日 | 2008-08-08 | 公開日 | 2008-08-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | DNA distortion and specificity in a sequence-specific endonuclease. J.Mol.Biol., 383, 2008
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3E3Y
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![BU of 3e3y by Molmil](/molmil-images/mine/3e3y) | Q138F HincII bound to GTTAAC and cocrystallized with 5 mM Ca2+ | 分子名称: | 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DTP*DAP*DAP*DCP*DCP*DGP*DGP*DC)-3', CALCIUM ION, SODIUM ION, ... | 著者 | Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M. | 登録日 | 2008-08-08 | 公開日 | 2008-08-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | DNA distortion and specificity in a sequence-specific endonuclease. J.Mol.Biol., 383, 2008
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3E43
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![BU of 3e43 by Molmil](/molmil-images/mine/3e43) | Q138F HincII bound to GTTAAC and cocrystallized with 2.5 mM MgCl2 | 分子名称: | 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DTP*DAP*DAP*DCP*DCP*DGP*DGP*DC)-3', Type-2 restriction enzyme HindII, UNKNOWN ATOM OR ION | 著者 | Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M. | 登録日 | 2008-08-08 | 公開日 | 2008-08-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | DNA distortion and specificity in a sequence-specific endonuclease. J.Mol.Biol., 383, 2008
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3E45
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![BU of 3e45 by Molmil](/molmil-images/mine/3e45) | Q138F HincII bound to Noncognate DNA (GTGCAC) and Ca2+ | 分子名称: | 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DGP*DCP*DAP*DCP*DCP*DGP*DGP*DC)-3', CALCIUM ION, SODIUM ION, ... | 著者 | Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M. | 登録日 | 2008-08-08 | 公開日 | 2008-08-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | DNA distortion and specificity in a sequence-specific endonuclease. J.Mol.Biol., 383, 2008
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3E42
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![BU of 3e42 by Molmil](/molmil-images/mine/3e42) | Q138F HincII bound to GTCGAC and Ca2+ (cocrystallized) | 分子名称: | 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DCP*DGP*DAP*DCP*DCP*DGP*DGP*DC)-3', CALCIUM ION, SODIUM ION, ... | 著者 | Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M. | 登録日 | 2008-08-08 | 公開日 | 2008-08-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | DNA distortion and specificity in a sequence-specific endonuclease. J.Mol.Biol., 383, 2008
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3E40
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![BU of 3e40 by Molmil](/molmil-images/mine/3e40) | Q138F HincII bound to GTTAAC and cocrystallized with 5 mM Ca2+ | 分子名称: | 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DP*DAP*DAP*DCP*DCP*DGP*DGP*DC)-3'), CALCIUM ION, SODIUM ION, ... | 著者 | Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M. | 登録日 | 2008-08-08 | 公開日 | 2008-08-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | DNA distortion and specificity in a sequence-specific endonuclease. J.Mol.Biol., 383, 2008
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1EON
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![BU of 1eon by Molmil](/molmil-images/mine/1eon) | ECORV BOUND TO 3'-S-PHOSPHOROTHIOLATE DNA AND CA2+ | 分子名称: | ACETIC ACID, CHLORIDE ION, DNA (5'-D(*AP*AP*AP*GP*AP*(TSP)P*AP*TP*CP*TP*T)-3'), ... | 著者 | Horton, N.C, Connolly, B.A, Perona, J.J. | 登録日 | 2000-03-23 | 公開日 | 2000-04-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Inhibition of EcoRV Endonuclease by Deoxyribo-3'-S-phosphorothiolates: A High-Resolution X-ray Crystallographic Study J.Am.Chem.Soc., 122, 2000
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1EO3
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![BU of 1eo3 by Molmil](/molmil-images/mine/1eo3) | INHIBITION OF ECORV ENDONUCLEASE BY DEOXYRIBO-3'-S-PHOSPHOROTHIOLATES: A HIGH RESOLUTION X-RAY CRYSTALLOGRAPHIC STUDY | 分子名称: | ACETIC ACID, DNA (5'-D(*CP*AP*AP*GP*AP*(TSP)P*AP*TP*CP*TP*T)-3'), MAGNESIUM ION, ... | 著者 | Horton, N.C, Connolly, B.A, Perona, J.J. | 登録日 | 2000-03-21 | 公開日 | 2000-04-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Inhibition of EcoRV Endonuclease by Deoxyribo-3'-S-phosphorothiolates: A High-Resolution X-ray Crystallographic Study J.Am.Chem.Soc., 122, 2000
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