6BK3
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![BU of 6bk3 by Molmil](/molmil-images/mine/6bk3) | Crystal structure of Os79 from O. sativa in complex with UDP and deoxynivalenol-3-glucoside (glucose moitey not resolved) | 分子名称: | (3alpha,7alpha)-3,7,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one, UDP-glycosyltransferase 79, URIDINE-5'-DIPHOSPHATE | 著者 | Wetterhorn, K, Gabardi, K, Rayment, I. | 登録日 | 2017-11-07 | 公開日 | 2017-11-29 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Determinants and Expansion of Specificity in a Trichothecene UDP-Glucosyltransferase from Oryza sativa. Biochemistry, 56, 2017
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6BK0
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6BK1
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6BK2
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5TME
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![BU of 5tme by Molmil](/molmil-images/mine/5tme) | Crystal structure of Os79 from O. sativa in complex with UDP. | 分子名称: | Glycosyltransferase, Os79, URIDINE-5'-DIPHOSPHATE | 著者 | Wetterhorn, K.M, Newmister, S.A, Caniza, R.K, Busman, M, McCormick, S.P, Berthiller, F, Adam, G, Rayment, I. | 登録日 | 2016-10-12 | 公開日 | 2016-11-02 | 最終更新日 | 2022-03-16 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Crystal Structure of Os79 (Os04g0206600) from Oryza sativa: A UDP-glucosyltransferase Involved in the Detoxification of Deoxynivalenol. Biochemistry, 55, 2016
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5TMB
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![BU of 5tmb by Molmil](/molmil-images/mine/5tmb) | Crystal structure of Os79 from O. sativa in complex with UDP. | 分子名称: | Glycosyltransferase, Os79, URIDINE-5'-DIPHOSPHATE | 著者 | Wetterhorn, K.M, Newmister, S.A, Caniza, R.K, Busman, M, McCormick, S.P, Berthiller, F, Adam, G, Rayment, I. | 登録日 | 2016-10-12 | 公開日 | 2016-11-02 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Crystal Structure of Os79 (Os04g0206600) from Oryza sativa: A UDP-glucosyltransferase Involved in the Detoxification of Deoxynivalenol. Biochemistry, 55, 2016
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5TMD
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![BU of 5tmd by Molmil](/molmil-images/mine/5tmd) | Crystal structure of Os79 from O. sativa in complex with U2F and trichothecene. | 分子名称: | Glycosyltransferase, Os79, URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE, ... | 著者 | Wetterhorn, K, Newmister, S.A, Caniza, R.K, Busman, M, McCormick, S.P, Berthiller, F, Adam, G, Rayment, I. | 登録日 | 2016-10-12 | 公開日 | 2016-11-02 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Crystal Structure of Os79 (Os04g0206600) from Oryza sativa: A UDP-glucosyltransferase Involved in the Detoxification of Deoxynivalenol. Biochemistry, 55, 2016
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6OUX
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![BU of 6oux by Molmil](/molmil-images/mine/6oux) | Structure of SMUL_1544, a decarboxylase from Sulfurospirillum multivorans | 分子名称: | Threonine phosphate decarboxylase-like enzyme | 著者 | Wetterhorn, K.M, Rayment, I, Vecellio, A, Seeger, M, Keller, S, Schubert, T. | 登録日 | 2019-05-05 | 公開日 | 2019-06-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Structural and functional analysis of an l-serine O-phosphate decarboxylase involved in norcobamide biosynthesis. Febs Lett., 593, 2019
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3NUL
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![BU of 3nul by Molmil](/molmil-images/mine/3nul) | Profilin I from Arabidopsis thaliana | 分子名称: | GLYCEROL, PROFILIN I, SULFATE ION | 著者 | Thorn, K, Christensen, H.E.M, Shigeta, R, Huddler, D, Chua, N.-H, Shalaby, L, Lindberg, U, Schutt, C.E. | 登録日 | 1996-11-27 | 公開日 | 1997-12-03 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The crystal structure of a major allergen from plants. Structure, 5, 1997
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3SKK
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![BU of 3skk by Molmil](/molmil-images/mine/3skk) | Crystal structure of human arginase I in complex with the inhibitor FABH, Resolution 1.70 A, twinned structure | 分子名称: | Arginase-1, MANGANESE (II) ION, [(5S)-5-amino-5-carboxy-6,6-difluorohexyl](trihydroxy)borate(1-) | 著者 | Thorn, K.J, Di Costanzo, L, Christianson, D.W. | 登録日 | 2011-06-22 | 公開日 | 2011-07-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | 主引用文献 | Binding of alpha , alpha-disubstituted amino acids to arginase suggests new avenues for inhibitor design. J.Med.Chem., 54, 2011
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1GHU
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![BU of 1ghu by Molmil](/molmil-images/mine/1ghu) | NMR solution structure of growth factor receptor-bound protein 2 (GRB2) SH2 domain, 24 structures | 分子名称: | GRB2 | 著者 | Thornton, K.H, Mueller, W.T, Mcconnell, P, Zhu, G, Saltiel, A.R, Thanabal, V. | 登録日 | 1996-08-05 | 公開日 | 1997-01-27 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Nuclear magnetic resonance solution structure of the growth factor receptor-bound protein 2 Src homology 2 domain. Biochemistry, 35, 1996
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8EG5
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![BU of 8eg5 by Molmil](/molmil-images/mine/8eg5) | huCaspase-6 in complex with inhibitor 3a | 分子名称: | (3R,5S)-1-(ethanesulfonyl)-5-phenyl-N-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxamide (bound form), 1,2-ETHANEDIOL, Caspase-6 subunit p11, ... | 著者 | Zhao, Y, Fan, P, Liu, J, Wang, Y, Van Horn, K, Wang, D, Medina-Cleghorn, D, Lee, P, Bryant, C, Altobelli, C, Jaishankar, P, Ng, R.A, Ambrose, A.J, Tang, Y, Arkin, M.R, Renslo, A.R. | 登録日 | 2022-09-11 | 公開日 | 2023-05-10 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Engaging a Non-catalytic Cysteine Residue Drives Potent and Selective Inhibition of Caspase-6. J.Am.Chem.Soc., 145, 2023
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8EG6
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![BU of 8eg6 by Molmil](/molmil-images/mine/8eg6) | huCaspase-6 in complex with inhibitor 2a | 分子名称: | (3R)-1-(ethanesulfonyl)-N-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxamide, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | Zhao, Y, Fan, P, Liu, J, Wang, Y, Van Horn, K, Wang, D, Medina-Cleghorn, D, Lee, P, Bryant, C, Altobelli, C, Jaishankar, P, Ng, R.A, Ambrose, A.J, Tang, Y, Arkin, M.R, Renslo, A.R. | 登録日 | 2022-09-11 | 公開日 | 2023-05-10 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Engaging a Non-catalytic Cysteine Residue Drives Potent and Selective Inhibition of Caspase-6. J.Am.Chem.Soc., 145, 2023
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6HIX
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![BU of 6hix by Molmil](/molmil-images/mine/6hix) | Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the large mitoribosomal subunit | 分子名称: | 12S rRNA, 50S ribosomal protein L13, putative, ... | 著者 | Ramrath, D.J.F, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, K, Leitner, A, Boehringer, D, Schneider, A, Ban, N. | 登録日 | 2018-08-31 | 公開日 | 2018-09-26 | 最終更新日 | 2019-02-06 | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | 主引用文献 | Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes. Science, 362, 2018
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4M17
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![BU of 4m17 by Molmil](/molmil-images/mine/4m17) | Crystal Structure of Surfactant Protein-D D325A/R343V mutant | 分子名称: | CALCIUM ION, Pulmonary surfactant-associated protein D | 著者 | Goh, B.C, Rynkiewicz, M.J, Cafarella, T.R, White, M.R, Hartshorn, K.L, Allen, K, Crouch, E.C, Calin, O, Seeberger, P.H, Schulten, K, Seaton, B.A. | 登録日 | 2013-08-02 | 公開日 | 2013-12-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.096 Å) | 主引用文献 | Molecular mechanisms of inhibition of influenza by surfactant protein d revealed by large-scale molecular dynamics simulation. Biochemistry, 52, 2013
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4M18
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![BU of 4m18 by Molmil](/molmil-images/mine/4m18) | Crystal Structure of Surfactant Protein-D D325A/R343V mutant in complex with trimannose (Man-a1,2Man-a1,2Man) | 分子名称: | CALCIUM ION, Pulmonary surfactant-associated protein D, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, ... | 著者 | Goh, B.C, Rynkiewicz, M.J, Cafarella, T.R, White, M.R, Hartshorn, K.L, Allen, K, Crouch, E.C, Calin, O, Seeberger, P.H, Schulten, K, Seaton, B.A. | 登録日 | 2013-08-02 | 公開日 | 2013-12-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.203 Å) | 主引用文献 | Molecular mechanisms of inhibition of influenza by surfactant protein d revealed by large-scale molecular dynamics simulation. Biochemistry, 52, 2013
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6BBD
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![BU of 6bbd by Molmil](/molmil-images/mine/6bbd) | Structure of N-glycosylated porcine surfactant protein-D complexed with glycerol | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | 著者 | van Eijk, M, Rynkiewicz, M.J, Khatri, K, Leymarie, N, Zaia, J, White, M.R, Hartshorn, K.L, Cafarella, T.R, van Die, I, Hessing, M, Seaton, B.A, Haagsman, H.P. | 登録日 | 2017-10-18 | 公開日 | 2018-05-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.898 Å) | 主引用文献 | Lectin-mediated binding and sialoglycans of porcine surfactant protein D synergistically neutralize influenza A virus. J. Biol. Chem., 293, 2018
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6BBE
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![BU of 6bbe by Molmil](/molmil-images/mine/6bbe) | Structure of N-glycosylated porcine surfactant protein-D | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | van Eijk, M, Rynkiewicz, M.J, Khatri, K, Leymarie, N, Zaia, J, White, M.R, Hartshorn, K.L, Cafarella, T.R, van Die, I, Hessing, M, Seaton, B.A, Haagsman, H.P. | 登録日 | 2017-10-18 | 公開日 | 2018-05-23 | 最終更新日 | 2021-03-24 | 実験手法 | X-RAY DIFFRACTION (1.898 Å) | 主引用文献 | Lectin-mediated binding and sialoglycans of porcine surfactant protein D synergistically neutralize influenza A virus. J. Biol. Chem., 293, 2018
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4L52
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![BU of 4l52 by Molmil](/molmil-images/mine/4l52) | Crystal Structure of 1-(4-{4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)furo[2,3-c]pyridin-4-yl]-1H-pyrazol-1-yl}piperidin-1-yl)ethan-1-one bound to TAK1-TAB1 | 分子名称: | 1-(4-{4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)furo[2,3-c]pyridin-4-yl]-1H-pyrazol-1-yl}piperidin-1-yl)ethanone, Mitogen-activated protein kinase kinase kinase 7, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera | 著者 | Wang, J, Hornberger, K.R, Crew, A.P, Jestel, A, Maskos, K, Moertl, M. | 登録日 | 2013-06-10 | 公開日 | 2013-07-03 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Discovery and optimization of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1. Bioorg.Med.Chem.Lett., 23, 2013
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4L3P
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![BU of 4l3p by Molmil](/molmil-images/mine/4l3p) | Crystal Structure of 2-(1-benzothiophen-7-yl)-4-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[2,3-c]pyridin-7-amine bound to TAK1-TAB1 | 分子名称: | 2-(1-benzothiophen-7-yl)-4-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[2,3-c]pyridin-7-amine, Mitogen-activated protein kinase kinase kinase 7, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera | 著者 | Wang, J, Hornberger, K.R, Crew, A.P, Steinbacher, S, Maskos, K, Moertl, M. | 登録日 | 2013-06-06 | 公開日 | 2013-06-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Discovery and optimization of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1. Bioorg.Med.Chem.Lett., 23, 2013
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5N41
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![BU of 5n41 by Molmil](/molmil-images/mine/5n41) | Archaeal DNA polymerase holoenzyme - SSO6202 at 1.35 Ang resolution | 分子名称: | 1,2-ETHANEDIOL, PolB1 Binding Protein 2 | 著者 | Yan, J, Beattie, T.R, Rojas, A.L, Schermerhorn, K, Gristwood, T, Trinidad, J.C, Albers, S.V, Roversi, P, Gardner, A.F, Abrescia, N.G.A, Bell, S.D. | 登録日 | 2017-02-09 | 公開日 | 2017-05-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.351 Å) | 主引用文献 | Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme. Nat Commun, 8, 2017
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5NR6
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5NR5
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5N35
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![BU of 5n35 by Molmil](/molmil-images/mine/5n35) | Gadolinium phased PBP2 (SSO6202) at 2.2 Ang | 分子名称: | GADOLINIUM ATOM, GLYCEROL, NITRATE ION, ... | 著者 | Yan, J, Beattie, T.R, Rojas, A.L, Schermerhorn, K, Gristwood, T, Trinidad, J.C, Albers, S.V, Roversi, P, Gardner, A.F, Abrescia, N.G.A, Bell, S.D. | 登録日 | 2017-02-08 | 公開日 | 2017-05-17 | 最終更新日 | 2017-12-06 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme. Nat Commun, 8, 2017
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5K87
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