6G7E
 
 | |
6GPG
 | | Structure of the RIG-I Singleton-Merten syndrome variant C268F | | Descriptor: | MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*CP*G)-3'), ... | | Authors: | Laessig, C, Lammens, K, Hopfner, K.-P. | | Deposit date: | 2018-06-05 | | Release date: | 2018-08-08 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.894 Å) | | Cite: | Unified mechanisms for self-RNA recognition by RIG-I Singleton-Merten syndrome variants.
Elife, 7, 2018
|
|
4YVZ
 | | Structure of Thermotoga maritima DisA in complex with 3'-dATP/Mn2+ | | Descriptor: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, DNA integrity scanning protein DisA, MANGANESE (II) ION | | Authors: | Mueller, M, Deimling, T, Hopfner, K.-P, Witte, G. | | Deposit date: | 2015-03-20 | | Release date: | 2015-06-03 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.495 Å) | | Cite: | Structural analysis of the diadenylate cyclase reaction of DNA-integrity scanning protein A (DisA) and its inhibition by 3'-dATP.
Biochem.J., 469, 2015
|
|
4YXM
 | | Structure of Thermotoga maritima DisA D75N mutant with reaction product c-di-AMP | | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, (4S)-2-METHYL-2,4-PENTANEDIOL, DNA integrity scanning protein DisA | | Authors: | Mueller, M, Deimling, T, Hopfner, K.-P, Witte, G. | | Deposit date: | 2015-03-23 | | Release date: | 2015-06-03 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural analysis of the diadenylate cyclase reaction of DNA-integrity scanning protein A (DisA) and its inhibition by 3'-dATP.
Biochem.J., 469, 2015
|
|
4YXJ
 | | Structure of Thermotoga maritima DisA in complex with ApCpp | | Descriptor: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA integrity scanning protein DisA | | Authors: | Mueller, M, Deimling, T, Hopfner, K.-P, Witte, G. | | Deposit date: | 2015-03-23 | | Release date: | 2015-06-03 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structural analysis of the diadenylate cyclase reaction of DNA-integrity scanning protein A (DisA) and its inhibition by 3'-dATP.
Biochem.J., 469, 2015
|
|
5EOG
 | |
5EOM
 | | Structure of full-length human MAB21L1 with bound CTP | | Descriptor: | CITRIC ACID, CYTIDINE-5'-TRIPHOSPHATE, Protein mab-21-like 1, ... | | Authors: | de Oliveira Mann, C.C, Witte, G, Hopfner, K.-P. | | Deposit date: | 2015-11-10 | | Release date: | 2016-06-01 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structural and biochemical characterization of the cell fate determining nucleotidyltransferase fold protein MAB21L1.
Sci Rep, 6, 2016
|
|
5DA9
 | | ATP-gamma-S bound Rad50 from Chaetomium thermophilum in complex with the Rad50-binding domain of Mre11 | | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Putative double-strand break protein, ... | | Authors: | Seifert, F.U, Lammens, K, Stoehr, G, Kessler, B, Hopfner, K.-P. | | Deposit date: | 2015-08-19 | | Release date: | 2016-03-02 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural mechanism of ATP-dependent DNA binding and DNA end bridging by eukaryotic Rad50.
Embo J., 35, 2016
|
|
5DAC
 | | ATP-gamma-S bound Rad50 from Chaetomium thermophilum in complex with DNA | | Descriptor: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), ... | | Authors: | Seifert, F.U, Lammens, K, Stoehr, G, Kessler, B, Hopfner, K.-P. | | Deposit date: | 2015-08-19 | | Release date: | 2016-03-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.503 Å) | | Cite: | Structural mechanism of ATP-dependent DNA binding and DNA end bridging by eukaryotic Rad50.
Embo J., 35, 2016
|
|
4YKE
 | |
4WK1
 | | Crystal structure of Staphylococcus aureus PstA in complex with c-di-AMP | | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, CALCIUM ION, PstA | | Authors: | Mueller, M, Hopfner, K.-P, Witte, G. | | Deposit date: | 2014-10-01 | | Release date: | 2014-11-26 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | c-di-AMP recognition by Staphylococcus aureus PstA.
Febs Lett., 589, 2015
|
|
4WK3
 | |
4WW4
 | |
4WZS
 | |
3OC3
 | | Crystal structure of the Mot1 N-terminal domain in complex with TBP | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HELICASE MOT1, TRANSCRIPTION INITIATION FACTOR TFIID (TFIID-1) | | Authors: | Wollmann, P, Cui, S, Viswanathan, R, Berninghausen, O, Wells, M.N, Moldt, M, Witte, G, Butryn, A, Wendler, P, Beckmann, R, Auble, D.T, Hopfner, K.-P. | | Deposit date: | 2010-08-09 | | Release date: | 2011-07-13 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP.
Nature, 475, 2011
|
|
3OCI
 | | Crystal structure of TBP (TATA box binding protein) | | Descriptor: | 1,2-ETHANEDIOL, TRANSCRIPTION INITIATION FACTOR TFIID (TFIID-1) | | Authors: | Cui, S, Wollmann, P, Moldt, M, Hopfner, K.-P. | | Deposit date: | 2010-08-10 | | Release date: | 2011-07-13 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.899 Å) | | Cite: | Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP.
Nature, 475, 2011
|
|
4IMK
 | | Uncrossed Fab binding to human Angiopoietin 2 | | Descriptor: | GLYCEROL, Heavy Chain, Light Chain, ... | | Authors: | Fenn, S, Schiller, C, Griese, J.J, Hopfner, K.-P, Kettenberger, H. | | Deposit date: | 2013-01-03 | | Release date: | 2013-04-17 | | Last modified: | 2013-05-22 | | Method: | X-RAY DIFFRACTION (2.202 Å) | | Cite: | Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.
Plos One, 8, 2013
|
|
4IML
 | | CrossFab binding to human Angiopoietin 2 | | Descriptor: | Crossed heavy chain (VH-Ckappa), Crossed light chain (VL-CH1), GLYCEROL | | Authors: | Fenn, S, Schiller, C, Griese, J, Hopfner, K.-P, Kettenberger, H. | | Deposit date: | 2013-01-03 | | Release date: | 2013-04-17 | | Last modified: | 2013-05-22 | | Method: | X-RAY DIFFRACTION (2.931 Å) | | Cite: | Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.
Plos One, 8, 2013
|
|
4KB6
 | |
7Z8S
 | | Mot1:TBP:DNA - post hydrolysis state | | Descriptor: | DNA (36-MER), Helicase-like protein, Putative tata-box binding protein | | Authors: | Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. | | Deposit date: | 2022-03-18 | | Release date: | 2023-03-29 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1.
Nat.Struct.Mol.Biol., 30, 2023
|
|
7Z7N
 | | Mot1E1434Q:TBP:DNA - substrate recognition state | | Descriptor: | DNA (36-MER), Helicase-like protein, Putative tata-box binding protein | | Authors: | Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. | | Deposit date: | 2022-03-16 | | Release date: | 2023-03-29 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (5.1 Å) | | Cite: | Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1.
Nat.Struct.Mol.Biol., 30, 2023
|
|
7ZB5
 | | Mot1(1-1836):TBP:DNA - post-hydrolysis complex dimer | | Descriptor: | DNA (36-MER), Helicase-like protein, Putative tata-box binding protein | | Authors: | Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. | | Deposit date: | 2022-03-23 | | Release date: | 2023-04-05 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1.
Nat.Struct.Mol.Biol., 30, 2023
|
|
7ZKE
 | | Mot1:TBP:DNA - pre-hydrolysis state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (36-MER), ... | | Authors: | Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. | | Deposit date: | 2022-04-12 | | Release date: | 2023-04-26 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1.
Nat.Struct.Mol.Biol., 30, 2023
|
|
