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PDB: 116 results

1XBS
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Crystal structure of human dim2: a dim1-like protein
Descriptor: Dim1-like protein
Authors:Simeoni, F, Arvai, A, Hopfner, K.-P, Bello, P, Gondeau, C, Heitz, F, Tainer, J, Divita, G.
Deposit date:2004-08-31
Release date:2005-08-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biochemical Characterization and Crystal Structure of a Dim1 Family Associated Protein: Dim2
Biochemistry, 44, 2005
1XEX
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Structural biochemistry of ATP-driven dimerization and DNA stimulated activation of SMC ATPases.
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SMC protein
Authors:Lammens, A, Schele, A, Hopfner, K.-P.
Deposit date:2004-09-13
Release date:2004-12-07
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural biochemistry of ATP-driven dimerization and DNA-stimulated activation of SMC ATPases
Curr.Biol., 14, 2004
1Z5Z
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Sulfolobus solfataricus SWI2/SNF2 ATPase C-terminal domain
Descriptor: Helicase of the snf2/rad54 family
Authors:Duerr, H, Koerner, C, Mueller, M, Hickmann, V, Hopfner, K.P.
Deposit date:2005-03-21
Release date:2005-05-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structures of the Sulfolobus solfataricus SWI2/SNF2 ATPase core and its complex with DNA
Cell(Cambridge,Mass.), 121, 2005
4I1S
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Melanoma differentiation associated protein-5 Helicase domain complex with inhibitor Non-structural protein V
Descriptor: Melanoma differentiation associated protein-5, Non-structural protein V, ZINC ION
Authors:Motz, C, Witte, G, Hopfner, K.P.
Deposit date:2012-11-21
Release date:2013-01-30
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.293 Å)
Cite:Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling.
Science, 339, 2013
1Z63
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Sulfolobus solfataricus SWI2/SNF2 ATPase core in complex with dsDNA
Descriptor: 5'-D(*AP*AP*AP*AP*AP*A*AP*TP*TP*GP*CP*CP*GP*AP*AP*GP*AP*CP*GP*AP*AP*AP*AP*AP*A)-3', 5'-D(*TP*TP*TP*TP*TP*TP*TP*CP*GP*TP*CP*TP*TP*CP*GP*GP*CP*AP*AP*TP*TP*TP*TP*TP*T)-3', Helicase of the snf2/rad54 family
Authors:Duerr, H, Koerner, C, Mueller, M, Hickmann, V, Hopfner, K.P.
Deposit date:2005-03-21
Release date:2005-05-17
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray structures of the Sulfolobus solfataricus SWI2/SNF2 ATPase core and its complex with DNA.
Cell(Cambridge,Mass.), 121, 2005
3BK7
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Structure of the complete ABCE1/RNAase-L Inhibitor protein from Pyrococcus abysii
Descriptor: ABC transporter ATP-binding protein, ADENOSINE-5'-DIPHOSPHATE, IRON/SULFUR CLUSTER, ...
Authors:Karcher, A, Hopfner, K.P.
Deposit date:2007-12-06
Release date:2007-12-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray Structure of the Complete ABC Enzyme ABCE1 from Pyrococcus abyssi
J.Biol.Chem., 283, 2008
4I1P
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Human MALT1 (caspase-IG3) in complex with activity based-probe
Descriptor: ACETATE ION, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, tetrapeptide
Authors:Schlauderer, F, Lammens, K, Hopfner, K.P.
Deposit date:2012-11-21
Release date:2014-07-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.403 Å)
Cite:Activity-Based Probes for Detection of Active MALT1 Paracaspase in Immune Cells and Lymphomas.
Chem.Biol., 22, 2015
4IML
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CrossFab binding to human Angiopoietin 2
Descriptor: Crossed heavy chain (VH-Ckappa), Crossed light chain (VL-CH1), GLYCEROL
Authors:Fenn, S, Schiller, C, Griese, J, Hopfner, K.-P, Kettenberger, H.
Deposit date:2013-01-03
Release date:2013-04-17
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2.931 Å)
Cite:Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.
Plos One, 8, 2013
4KB6
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Structure of porcine cyclic GMP AMP synthase (CGAS) in complex with DNA, ATP and GTP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*GP*AP*CP*GP*CP*TP*AP*GP*CP*GP*TP*CP*G)-3'), GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Deimling, T, Hopfner, K.-P.
Deposit date:2013-04-23
Release date:2013-06-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.0754 Å)
Cite:Structural mechanism of cytosolic DNA sensing by cGAS.
Nature, 498, 2013
3M85
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Archaeoglobus fulgidus exosome y70a with RNA bound to the active site
Descriptor: 5'-R(*CP*UP*CP*CP*CP*C)-3', Probable exosome complex exonuclease 1, Probable exosome complex exonuclease 2, ...
Authors:Hartung, S, Hopfner, K.-P.
Deposit date:2010-03-17
Release date:2010-04-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Quantitative analysis of processive RNA degradation by the archaeal RNA exosome
Nucleic Acids Res., 38, 2010
4I1R
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Human MALT1 (caspase-IG3) in complex with thioridazine
Descriptor: 10-{2-[(2S)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, Mucosa-associated lymphoid tissue lymphoma translocation protein 1
Authors:Schlauderer, F, Lammens, K, Hopfner, K.P.
Deposit date:2012-11-21
Release date:2013-08-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Analysis of Phenothiazine Derivatives as Allosteric Inhibitors of the MALT1 Paracaspase.
Angew.Chem.Int.Ed.Engl., 52, 2013
3QB0
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Crystal structure of Actin-related protein Arp4 from S. cerevisiae complexed with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 4, CALCIUM ION
Authors:Fenn, S, Breitsprecher, D, Gerhold, C.B, Witte, G, Faix, J, Hopfner, K.P.
Deposit date:2011-01-12
Release date:2011-05-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.404 Å)
Cite:Structural biochemistry of nuclear actin-related proteins 4 and 8 reveals their interaction with actin.
Embo J., 30, 2011
3NWC
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Crystal Structure of the Pyrococcus furiosus SMC Protein Hinge Domain
Descriptor: SMC protein
Authors:Griese, J.J, Hopfner, K.P.
Deposit date:2010-07-09
Release date:2010-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6961 Å)
Cite:Structure and DNA-binding activity of the Pyrococcus furiosus SMC protein hinge domain
Proteins, 79, 2011
4JC5
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Immune activator bound to receptor
Descriptor: (9-oxoacridin-10(9H)-yl)acetic acid, Transmembrane protein 173
Authors:Deimling, T, Hopfner, K.P.
Deposit date:2013-02-21
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Species-specific detection of the antiviral small-molecule compound CMA by STING.
Embo J., 32, 2013
4JLZ
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Structure of porcine cGAS in complex with bound UTP
Descriptor: MAGNESIUM ION, URIDINE 5'-TRIPHOSPHATE, Uncharacterized protein, ...
Authors:Civril, F, Hopfner, K.P.
Deposit date:2013-03-13
Release date:2013-06-12
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural mechanism of cytosolic DNA sensing by cGAS
Nature, 498, 2013
4JLX
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Structure of porcine cyclic GMP-AMP synthase (cGAS)
Descriptor: GLYCEROL, MALONATE ION, TETRAETHYLENE GLYCOL, ...
Authors:Civril, F, Hopfner, K.P.
Deposit date:2013-03-13
Release date:2013-06-12
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Structural mechanism of cytosolic DNA sensing by cGAS
Nature, 498, 2013

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